Clinical trials: Spastic Diplegic Cerebral Palsy
Diplegic Cerebral Palsy
Action Observation in Children With Diplegic Cerebral Palsy
A new rehabilitative approach, called AOT, based on the discovery of mirror neuron system (MNS), has been used with promising results on the Upper Limb (UL) function in some studies in children with Cerebral Palsy (CP).
- Trial name
- NCT05223257
- Testing
- AOT
- Where
- 3 sites in Italy
- Volunteers
- 54 people
- Sponsor
- IRCCS Fondazione Stella Maris
Spastic Diplegia, Cerebral Palsy
Effect of Core Stability Training on Segmental Trunk Control and Quality of Life in Children with Cerebral Palsy
Spastic diplegia is a common shape of cerebral palsy that significantly affects trunk control and quality of life in children. Core stability training (CST) has been utilized as a potential intervention to improve the trunk…
- Trial name
- NCT06822296
- Testing
- Physical Therapy, Designed rehabilitation program
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Cerebral Palsy, Spastic, Cerebral Palsy
The Validity and Reliability of the Turkish Version of TASC and the Relationship Between SMC and Motor Functions
Selective motor control (SMC) impairment in children with cerebral palsy (CP) includes movement patterns dominated by flexor or extensor synergy affecting functional movements.
- Conditions
- Cerebral Palsy, Spastic, Cerebral Palsy, Cerebral Palsy Spastic Diplegia, Cerebral Palsy Quadriplegic
- Trial name
- NCT04231227
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Gazi University
Burns
James EMBAR® Light Therapy in the Treatment of Burn Wounds of Intermediate Depth
This will be a prospective, randomized, single blinded, controlled study in a single center setting to assess the effect of either phototherapy with the Embar® light therapy or sham irradiation.
- Trial name
- NCT00329654
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- University Hospital, Ghent
Thrombotic Thrombocytopenic Purpura (TTP)
A Study of TAK-755 (rADAMTS13) With Little to No Plasma Exchange (PEX) Treatment in Adults With Immune-mediated Thrombotic Thrombocytopenic Purpura (iTTP)
This is a study of TAK-755 in adults with immune-mediated thrombotic thrombocytopenic purpura (iTTP). The main aim of this study is to determine the percentage of participants with a clinical (Part 1) or platelet (Part 2)…
- Trial name
- NCT05714969
- Testing
- TAK-755
- Where
- 22 sites in United States, Austria and 4 more
- Volunteers
- 29 people
- Sponsor
- Takeda
Autism Spectrum Disorder
Assessment of the Usability/acceptability of the Little Journey App by Parents/guardians/legal Representatives and Children Aged Between 3-12 Years Old Who Have a Diagnosis of Autism Spectrum Disorder (ASD).
Assessment of the usability/ acceptability of the Little Journey app with children aged between 3-12 years old with a diagnosis of autism spectrum disorder (ASD) and experience of attending hospital for a procedure, and their…
- Trial name
- NCT06598358
- Where
- United Kingdom
- Volunteers
- 7 people
- Sponsor
- Little Journey
Smoking (Tobacco) Addiction
Addiction Potential of Very Low Nicotine Filtered Little Cigars
The goal of this clinical trial is to learn how reducing the nicotine content in filtered little cigars can affect the the use of these cigars and lung health in current adult filtered little cigar users.
- Trial name
- LOWFLC (NCT06630728)
- Testing
- Reduced Nicotine Content Cigars, Normal nicotine content cigar, Usual brand cigar
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Spastic Diplegia
Role of Dynamic Movement Intervention in Children with Spastic Diplegia
The study aims to investigate the effect of dynamic movement intervention approach on static and dynamic balance, quality of step length and cadence of walking pattern of children with spastic diplegic cerebral palsy.
- Trial name
- NCT06270550
- Testing
- Dynamic Movement Intervention
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Obesity, Insulin Resistance
Diabetes Prevention Program for Obese Latino Youth
The purpose of this study is to examine the effects of 12 week lifestyle intervention on diabetes risk in obese Latino adolescents.
- Conditions
- Obesity, Insulin Resistance, Diabetes
- Trial name
- ELSC (NCT02039141)
- Testing
- Every Little Step Counts Intervention
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Parental Support, Emotion Regulation
Little ACF (Lilla ABC): Evaluation of a Parental Support Program for Parents of Children Aged 1-2 Years
Society can promote children's mental health at an early stage by creating good conditions with, for example, general parental support programs that are offered to all parents.
- Conditions
- Parental Support, Emotion Regulation, Coping Behavior, Stress, Emotional
- Trial name
- NCT05445141
- Testing
- Little ACF [in Swedish: Lilla ABC], Lectures
- Where
- Sweden
- Volunteers
- 732 people
- Sponsor
- Karolinska Institutet
Tobacco Use
Little Cigar and Cigarillo Warnings Among US Adults Who Use LCCs
The goal of this research is to assess whether little Cigars and cigarillos (LCC) warnings developed by the study team are more effective than the current warnings proposed by FDA for LCC products.
- Trial name
- NCT05849051
- Testing
- Newly developed warnings with images at 30% size, FDA proposed text-only warnings at 30% size
- Where
- United States
- Volunteers
- 1,029 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Spastic Diplegic Cerebral Palsy
Effects of Transcranial Direct Current Stimulation Combined With Virtual Reality on Gait and Self-Esteem in Children With Spastic Cerebral Palsy
Cerebral palsy can affect walking ability, muscle control, functional mobility, and psychosocial well-being in children. Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique that may…
- Trial name
- NCT07829796
- Testing
- Active Transcranial Direct Current Stimulation, Virtual Reality Rehabilitation, Conventional Physical Therapy
- Where
- 2 sites in Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Depression, Multiple Chronic Conditions
An Approach to "Move a Little & Often" With Health Conditions
People with long term conditions such as diabetes and arthritis, and who also have depression spend a lot of time sedentary during the day. This is because they face many barriers to being active, such as pain and fatigue.
- Trial name
- NCT03537053
- Testing
- A plan to Move a Little and Often
- Where
- 2 sites in United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Manchester
Cerebral Palsy
Effects of Routine Physical Therapy With and Without Neurodevelopmental Technique on GMF, Spasticity and HRQOL in Diplegic CP
The aim of this study is to investigate the effects of routine physical therapy with and without neurodevelopmental technique on gross motor function, spasticity and health related quality of life in diplegic cerebral palsy.
- Trial name
- NCT06444230
- Testing
- Routine Physical therapy with Neurodevelopmental technique, Routine Physical therapy
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- University of Lahore
Cerebral Palsy, Diplegic Cerebral Palsy
Effects of Lower Extremities Cycling Functional Electrıcal Stimulation Training in Cerebral Palsy
The aim of this study was to investigate the effects of cycling functional electrical stimulation applied to the lower extremities of children with spastic diplegic cerebral palsy (CP) on the gait parameters and daily living…
- Trial name
- NCT03600012
- Testing
- Cycling Functional Electrical Stimulation, Physiotherapy
- Volunteers
- 20 people
- Sponsor
- Hacettepe University
Cerebral Palsy, Spastic
The Effectiveness of Repetitive Transcranial Magnetic Stimulation for Spastic Diplegia Cerebral Palsy
Cerebral palsy describes a group of permanent disorders of the development of movement and posture, causing activity limitation that are attributed to non-progressive disturbances that occurred in the developing fetal or infant…
- Trial name
- NCT05198921
- Testing
- repetitive Transcranial Magnetic Stimulation
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universitat de Lleida
Cerebral Palsy, Spastic Diplegia
Pelvic Alignment in Relation to Standing Balance and Selective Motor Control in Children With Spastic Diplegia
This study will be conducted to identify the relation between pelvic alignment and standing balance and also the relation between pelvic alignment and selective motor control in children with spastic diplegic cerebral palsy.
- Trial name
- NCT05014451
- Volunteers
- 40 people
- Sponsor
- Cairo University
Spastic Diplegic Cerebral Palsy, Cerebral Palsy
Therapeutic Listening for Balance and Trunk Control in Children With Cerebral Palsy
This study evaluates whether adding Therapeutic Listening to a structured physiotherapy program can improve balance, trunk control, and reaction time in children with spastic diplegic cerebral palsy.
- Trial name
- TL-CSB-CP (NCT07808437)
- Testing
- Conventional Training, Therapeutic Listening
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- MTI University
Prediabetes, Diabetes
Pilot Study of "Bottarga" Supplementation: A Little-known, Sustainable "Blue" Food
This pilot study aims to explore the potential benefits of consuming Greek bottarga (grey mullet fish roe) in individuals with at least one metabolic abnormality (low HDL cholesterol, high LDL cholesterol, high triglycerides…
- Conditions
- Prediabetes, Diabetes, High Cholesterol/Hyperlipidemia, Obesity & Overweight
- Trial name
- NCT06988462
- Testing
- Bottarga, Comparator
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cambridge Health Alliance
Spastic Diplegia Cerebral Palsy, Spastic Hemiplegia
Spinal Mobility in Children With Cerebral Palsy: NDT-Bobath and Exergaming
The purpose of this study is to evaluate changes in spinal mobility in the cervical, thoracic, and lumbar regions in children with cerebral palsy aged 10-15 years.
- Trial name
- NCT07421505
- Testing
- NDT-Bobath Therapy, Sitting Exergaming, Standing Exergaming
- Where
- 2 sites in Poland
- Volunteers
- 42 people
- Sponsor
- Wroclaw University of Health and Sport Sciences