Clinical trials: Spastic Diplegic Cerebral Palsy
IVF Treatment, Human Epididymal Secretory Protein E4
Serum Biomarker HE4 During IVF Treatment
Human epididymal secretory protein 4 (HE4) is a new biomarker for ovarian cancer. The effect of IVF stimulation will be evaluated in order to see whether severe hormonal changes in the gonadotrophin and steroid status affect the…
- Trial name
- FHE4 (NCT01576744)
- Where
- Finland
- Volunteers
- 20 people
- Sponsor
- Turku University Hospital
ADHD
Little Flower Yoga for Kids: Evaluation of a Yoga and Mindfulness Program for Children With Increased Levels of Emotion Dysregulation and Inattention
An initial evaluation of Little Flower Yoga for Kids will be conducted in a small sample of 18-30 Kindergarten and First Grade students (3-5 per class) enrolled in Girls Preparatory Charter School of the Bronx.
- Trial name
- NCT02829528
- Testing
- Little Flower Yoga For Kids
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- New York University
Ischemic Stroke, Physical Activity
Physical Activity Immediately After Acute Cerebral Ischemia
Stroke is the leading cause of adult disability in Europe and United States and the second leading cause of death worldwide and affects more than 10,000 Danes each year.
- Trial name
- NCT01560520
- Testing
- Physical activity
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Hillerod Hospital, Denmark
Cerebral Palsy (CP), Spastic Diplegia Cerebral Palsy
Dynamic Surface Exercise Training and Static Surface Exercise Training in Cerebral Palsy Children
This randomized clinical trial aims to compare the effects of Dynamic Surface Exercise Training (DSET) and Static Surface Exercise Training (SSET) on balance and gross motor function in children with spastic diplegic cerebral…
- Conditions
- Cerebral Palsy (CP), Spastic Diplegia Cerebral Palsy, Gross Motor Functions, Balance
- Trial name
- NCT07129785
- Testing
- Dynamic Surface Exercise Training (DSET), Static Surface Exercise Training (SSET)
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- University of Lahore
Cerebral Palsy
Effect of Different Stretching Techniques
The aim of this study is to investigate the effect of proprioceptive neuromuscular facilitation (PNF) and static stretching techniques on the balance and functional capabilities of children diagnosed with diplegic cerebral palsy…
- Trial name
- NCT06608693
- Testing
- PNF stretching, Static stretching group
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Gazi University
Little Cigars and Cigarillos (LCC) Use
Little Cigar and Cigarillo Warnings for Youth
This study explores the effect of the little cigars and cigarillos (LCC) warnings on youth who currently use, have ever used, or are susceptible to using LCCs.
- Trial name
- NCT06413797
- Testing
- FDA warnings + Image, FDA Warnings Text-Only, Surgeon General Text-Only Warnings
- Where
- United States
- Volunteers
- 928 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Cerebral Palsy
Effect of Virtual Reality in Spider Cage on Gross Motor Performance and Balance in Children With Spastic Diplegia
This study will detect the effect of virtual reality in spider cage on gross motor performance and balance in children with spastic diplegia.
- Trial name
- NCT05740020
- Testing
- virtual reality glasses, The traditional exercise program
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Amr Mohsen Mohamed Abo Khatwa
Cerebral Palsy, Balance; Distorted
Investigation of the Effect of Hippotherapy Simulator in Children With Spastic Diplegia and Cerebral Palsy
The aim of the study is to examine the effect of hippotherapy simulator on trunk control, balance and gait in children with spastic diplegia cerebral palsy and its relationship with quality of life.
- Conditions
- Cerebral Palsy, Balance; Distorted, Walking, Difficulty
- Trial name
- NCT06003868
- Testing
- traditional physiotherapy, hippotherapy-assisted physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Uskudar University
Diplegic Cerebral Palsy
Diplegic Cerebral Palsy and Action Observation Training
In this study, video-based action observation training and live action observation training in children with spastic diplegic cerebral palsy; It was aimed to examine the effect on motor function, activity participation and…
- Trial name
- NCT05209282
- Testing
- Video Based Action Observation, Live Action Observation, Conventional physiotherapy program
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Inonu University
Diplegia, Spastic
The Effect of Fine Motor Skills Training Through Telerehabilitation in Children With Diplegic Cerebral Palsy
The aim of this study is to compare the effect of occupational therapy intervention through two-way video call, versus occupational therapy home program in written form; on handwriting skills, occupational performance, fine motor…
- Trial name
- NCT05169294
- Testing
- Telerehabilitation Program, Written Home Program
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ekin Akpınar
Spastic Diplegia
Cortical Plasticity in Spastic Diplegia After Selective Dorsal Rhizotomy
The purpose of this study is to characterize the cortical connectivity changes in the brain of spastic diplegic children after Selective Dorsal Rhizotomy.
- Trial name
- NCT02535936
- Testing
- 3Tesla MRI with DTI-MRI and rsfcMRI under general anesthesia
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- The University of Texas Health Science Center, Houston
Spastic Diplegic Cerebral Palsy, Hemiplegic Cerebral Palsy
Strength Training in Children With Spastic Diplegic and Hemiplegic Cerebral Palsy Receiving Botulinum Toxin
To estimate the effectiveness of strength training after administration of botulinum toxin in children with spastic diplegic cerebral palsy and hemiplegic cerebral palsy on muscle volume and gross motor function.
- Trial name
- NCT04177186
- Testing
- Strength training, Strength training with botulinum toxin
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Asir John Samuel
Cerebral Palsy (CP), Spastic Diplegia Cerebral Palsy
Effect of Reactive Functional Motor Challenge Training on Dynamic Balance and Functional Mobility in Children With Spastic Diplegic Cerebral Palsy: A Randomized Comparative Trial.
To investigate the effect of Reactive Functional Motor Challenge Training on dynamic balance and functional mobility in children with spastic diplegic cerebral palsy.
- Trial name
- NCT07732881
- Testing
- Reactive Functional Motor Challenge Training, Conventional Physical Therapy Program
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Badr University
Major Depressive Disorder
IM and IV SPL026 Drug Product in Healthy Participants
The goal of this clinical trial is to test SPL026 given via injection into a muscle in healthy volunteers.
- Trial name
- NCT05644093
- Testing
- SPL026 IV, SPL026 IM
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Small Pharma Ltd
Cerebral Palsy
Effects of Shockwave Therapy on Crouched Gait Due to Hamstring Flexibility in Cerebral Palsy Children
Randomized controlled trial will be conducted on thirty-two cerebral palsy children in Punjab Special School. Spastic Diplegic CP children with GMFCs level III, IV, V with age range of 6 to 12.
- Trial name
- NCT06460714
- Testing
- Shock wave therapy, stretching and orthosis, Stretching, strengthening and orthosis
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Difficult Airway, Difficult Airway Intubation
SEALion: Study on Supplemental Oxygenation Via Nasal Cannula for Young Children During Intubation
Tracheal intubation in neonates can be technically challenging, even for experienced pediatric anesthesiologists, with a high first-attempt success rate crucial to ensure safety.
- Conditions
- Difficult Airway, Difficult Airway Intubation, Neonate
- Trial name
- SEALION (NCT06683599)
- Testing
- Apneic oxygenation
- Where
- 4 sites in Australia, Brazil and 2 more
- Volunteers
- 240 people
- Sponsor
- Vinícius C Quintão, MD, MSc, PhD
Cerebral Palsy, Spastic, Diplegic
Stretching and Strength Training for Improved Gait Function in Children With Spastic Cerebral Palsy
The purpose of this randomized and controlled intervention study is to explore the effect of a physiotherapy intervention targeting contract and spastic hamstring muscles in children having bilateral spastic cerebral palsy (CP)…
- Trial name
- NCT02917330
- Testing
- Stretching and progressive strength training
- Where
- Norway
- Volunteers
- 34 people
- Sponsor
- Oslo University Hospital
Diplegic Cerebral Palsy
Scooter Board Activities Versus Core Stability Exercises
Children with diplegic cerebral palsy (CP) often experience impaired trunk control and balance, which limits functional mobility. Core stability exercises are commonly used in pediatric physical therapy to improve trunk control.
- Trial name
- CP (NCT07132138)
- Testing
- Scooter Board Activities, Core Stability Exercises
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Badr University
Acute Pain, Procedural Anxiety
Little NIRVANA for Pediatric Pain and Anxiety
The aim of this study is to test the feasibility of using Little NIRVANA (augmented reality (AR)) for managing anxiety and pain for children 2-8 years old during hospital emergency peripheral intravenous (PIV) insertions.
- Conditions
- Acute Pain, Procedural Anxiety, Pediatric ALL, Emergency Medicine
- Trial name
- NCT06795126
- Testing
- Little NIRVANA
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Nationwide Children's Hospital
Cerebral Palsy Spastic Diplegia
Effect of Botulinum Toxin on Selective Motor Control and Pain in Diplegic Cerebral Palsy
The aim of this study is to investigate the effects of Botulinum Neurotoxin-A (BoNT-A) injection applied to spastic muscles on pain sensation and Selective Motor Control (SMC) in cases diagnosed with diplegic spastic Cerebral…
- Trial name
- NCT06583343
- Testing
- OnabotulinumtoxinA, Conventional Physical Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital