Clinical trials: Spastic Diplegic Cerebral Palsy
Smoking
Nicotine Metabolism and Little Cigars
This study examines the effects of smoking little cigars in different groups of smokers. The investigators are focusing on differences in how smokers' bodies break down and eliminate nicotine from their systems.
- Trial name
- NCT01898559
- Testing
- Switch to smoking only little cigars
- Where
- United States
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Cerebral Palsy, Spastic, Cerebral Palsy
The Validity and Reliability of the Turkish Version of TASC and the Relationship Between SMC and Motor Functions
Selective motor control (SMC) impairment in children with cerebral palsy (CP) includes movement patterns dominated by flexor or extensor synergy affecting functional movements.
- Conditions
- Cerebral Palsy, Spastic, Cerebral Palsy, Cerebral Palsy Spastic Diplegia, Cerebral Palsy Quadriplegic
- Trial name
- NCT04231227
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Gazi University
Acute Ischemic Stroke
Physical Activity Immediately After Acute Cerebral Ischemia 3
Stroke is the leading cause of adult disability in Europe and United States and the second leading cause of death worldwide and affects more than 10,000 Danes each year.
- Trial name
- NCT01712282
- Testing
- physical activity, 2 x 30 minutes/day
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Hillerod Hospital, Denmark
Hyperekplexia, CTNNB1 Gene Mutation
Hyperekplexia in Patients With CTNNB1 Mutation
A few years ago, a new genetic disorder (OMIM # 615075) has been associated with loss-of-function variations in the CTNNB1 gene.
- Trial name
- CTNNB1 (NCT05168969)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Child, Only
Effects of Dynamic Surface Exercise Training in Children With Diplegic Cerebral Palsy
Data will be collected after the approval of synopsis a total of 14 children with diplegic cerebral palsy of age between 6 and 8 years of both genders with Gross Motor Function Classification System of level III and IV will be…
- Trial name
- NCT07244159
- Testing
- Dynamic surface exercise training, Standard physiotherapy Training
- Where
- Pakistan
- Volunteers
- 14 people
- Sponsor
- Riphah International University
Cerebral Palsy Spastic Diplegia
Effect of Eye Movement Exercise on Gait Spatial and Temporal Parameters in Cerebral Palsy Spastic Diplegic Children
The purpose of this study is to determine if there is an effect of eye movement training exercises on gait kinetic variables in cerebral palsy spastic diplegic children.
- Trial name
- NCT07000422
- Testing
- Selected gait training program, Eye movement exercise
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Spastic Diplegia Cerebral Palsy
Loaded and Task Specific Training in Spastic Diaplegic CP to Improve Gait and Functional Mobility.
Cerebral Palsy is a non-progressive condition caused by early brain injury that affects movement, posture, and muscle tone. Spastic diplegia mainly involves the lower limbs, leading to stiffness, weakness, and abnormal gait…
- Trial name
- ELTTS-GFM-SDCP (NCT07474818)
- Testing
- Loaded Treadmill Training, Task specific Training
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Cerebral Palsy Spastic Diplegia
Effect of Electrical Stimulation With Functional Task Training on Balance and Motor Abilities in Children With Diplegia
The aims of the study are to: 1. Investigate the combined effect of functional task training with electrical stimulation of bilateral hip abductor muscles on balance in children with diplegia. 2.
- Trial name
- NCT06234215
- Testing
- functional electrical stimulation, functional task training
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Cerebral Palsy, Spastic Diplegia
Gait Rehabilitation in Diplegic Children
Background: Standing and walking serve an individual's basic need to move from place to place, and both are the most common activities that people do on a daily basis.
- Trial name
- NCT05294874
- Testing
- gait training
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Cairo University
Cerebral Palsy
Effect of Designed Physical Training After Selective Dorsal Rhizotomy on Motor Function of Ambulant Children With Spastic Diplegia
The management of cerebral palsy is complex and requires a multidisciplinary approach. Selective dorsal rhizotomy is a neurosurgical technique that aims to reduce spasticity in the lower limbs and improve motor function.
- Trial name
- NCT04997044
- Testing
- Concomitant physical rehabilitation, Standard Orthotic Management, selective dorsal rhizotomy
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Cairo University
Hypoxic Brain Damage, Hypoxic Ischaemic Encephalopathy (HIE)
Intranasal AAV9-PHP.eB Gene Therapy in Cerebral Palsy (CP) & Hypoxic Ischemic Encephalopathy (HIE)
This international study, organized by Healing Hope International, is an observational registry designed to collect real-world data on participants living with chronic hypoxic ischemic encephalopathy (HIE) who receive an emerging…
- Conditions
- Hypoxic Brain Damage, Hypoxic Ischaemic Encephalopathy (HIE), Hypoxic Ischaemic Encephalopathy Due to Cardiac Arrest, Hypoxic Ischemic Encephalopathy of Newborn
- Trial name
- GEN-HOPE (NCT07264166)
- Where
- Mexico
- Volunteers
- 25 people
- Sponsor
- Healing Hope International
Diplegic Cerebral Palsy
Scooter Board Activities Versus Core Stability Exercises
Children with diplegic cerebral palsy (CP) often experience impaired trunk control and balance, which limits functional mobility. Core stability exercises are commonly used in pediatric physical therapy to improve trunk control.
- Trial name
- CP (NCT07132138)
- Testing
- Scooter Board Activities, Core Stability Exercises
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Badr University
Cerebral Palsy Spastic Diplegia
Virtual Reality Training With Sensory Integration On The Gross Motor Functions Of Lower Limb
The objectives of this study are To determine the effect of virtual reality on balance and gross motor functions of the lower limb in spastic diplegic cerebral palsy.
- Trial name
- NCT04467385
- Testing
- VR training + Sensory Integration therapy + conventional therapy, VR training + conventional therapy
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Cerebral Palsy, Diplegia, Spastic
Validity of the Kinematic Classification of Gait in Diplegic Children With Cerebral Palsy (CP)
In recent years Ferrari et al. proposed a new classification of gait in diplegic children with spastic diplegia that describes four different patterns of gait by analyzing the strategies that each children adopts to need his/her…
- Trial name
- NCT01158833
- Testing
- classification of gait in diplegic children with CP
- Where
- Italy
- Volunteers
- 86 people
- Sponsor
- University of Modena and Reggio Emilia
Major Depressive Disorder
IM and IV SPL026 Drug Product in Healthy Participants
The goal of this clinical trial is to test SPL026 given via injection into a muscle in healthy volunteers.
- Trial name
- NCT05644093
- Testing
- SPL026 IV, SPL026 IM
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Small Pharma Ltd
Acute Ischemic Stroke, Physical Activity
Physical Activity Immediately After Acute Cerebral Ischemia
Stroke is the leading cause of adult disability in Europe and United States and the second leading cause of death worldwide and affects more than 10,000 Danes each year.
- Conditions
- Acute Ischemic Stroke, Physical Activity, Accelerometer
- Trial name
- NCT01594190
- Testing
- physical activity 15 minutes/day, physical activity, 2 x 30 minutes/day
- Where
- Denmark
- Volunteers
- 250 people
- Sponsor
- Hillerod Hospital, Denmark
Septic Shock, Sepsis
Stress Doses of Hydrocortisone on Coagulation Dysfunction in Patients With Septic Shock
The purpose of this study is to find out whether stress doses of hydrocortisone attenuate coagulation dysfunction in patients with septic shock.
- Trial name
- NCT02266589
- Testing
- Hydrocortisone
- Volunteers
- 84 people
- Sponsor
- Nanjing PLA General Hospital
Cerebral Palsy, Spastic Diplegia
Effect of Physical Activity Intervention Children With Spastic Diplegia After Resistance Training
The purpose of this study is to investigate the effects of a 6-month physical activity intervention program on mobility and participation after the termination of a 6-week functional strengthening program for school-age children…
- Trial name
- NCT01367340
- Testing
- Loaded sit-to-stand resistance exercise, Physical activity intervention
- Where
- Taiwan
- Volunteers
- 32 people
- Sponsor
- National Taiwan University Hospital
Diplegic Cerebral Palsy
Individualized Comprehensive Home-Centred Activity Based Therapy for Children With Diplegic Cerebral Palsy
Activity based therapy is gaining interest for rehabilitation of children with cerebral palsy (CP). A home-based comprehensive programme structured on the principles of activity based therapy seems to hold promise in the field of…
- Trial name
- NCT02412007
- Testing
- Individualized comprehensive home centred activity based programme
- Where
- India
- Volunteers
- 59 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Diplegic Spastic Cerebral Palsy
Relationship Between Hip Extensor Strength and Gait Speed in Diplegic Cerebral Palsy
The hip extensors are essential for upright posture and forward propulsion during gait. Children with diplegic CP often demonstrate reduced muscle strength, which impacts their gait speed and overall mobility.
- Trial name
- NCT06913114
- Testing
- Lafayette
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University