Clinical trials: Spastic Gait
Spinal Cord Injuries (SCI), Paralysis, Lower Limbs
Epidural Electrical Stimulation to Restore Standing and Walking in Patients With Chronic Paralysis Due to Spinal Cord Injury: A Study on Motor Recovery, Spasticity Reduction, and Quality of Life Improvement Through Neuromodulation and Intensive Rehabilitation
Spinal cord injury (SCI) is a major cause of morbidity and disability worldwide, significantly impacting patients' quality of life and functional independence.
- Trial name
- EPISTIM-SCI (NCT06847295)
- Testing
- Epidural Electrical Stimulation (EES) using an implanted paddle lead and pulse generator combined with a 12-month intensive rehabilitation program.
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- University of Sao Paulo General Hospital
Stroke, Spasticity
Effects of Low-level Laser Therapy on Spasticity and Gait Parameters in Chronic Stroke Patients With Spastic Plantar Flexors
Stroke is one of the leading causes of long-term disability worldwide. Many patients who survive a stroke experience muscle stiffness (called spasticity), especially in the ankle and foot muscles, which makes walking difficult…
- Conditions
- Stroke, Spasticity, Plantar Flexors
- Trial name
- LLLT-STROKE (NCT07273591)
- Testing
- Low Level Laser Therapy, conventional physical therapy
- Where
- Pakistan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Montiha Azeem
Cerebral Palsy
Effects of Treadmill Training and Whole-body Vibration in Children With Cerebral Palsy
Whole-body vibration (WBV) and treadmill training (TT) are commonly-utilized rehabilitation interventions for children with neuromotor disorders.
- Trial name
- NCT04630392
- Testing
- Treadmill Training, Whole Body Vibration & Treadmill Training
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Georgia State University
Spastic Diplegia
Action Observation Therapy in Children With Spastic Diplegia
The aim of this study is to compare the effect of live versus video action observation training (AOT) on balance and gait in children with spastic diplegia.
- Trial name
- AOT/CP (NCT07651111)
- Testing
- A selected physical therapy program, Live action observation training (AOT), Video action observation training (AOT)
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Cairo University
Hemiplegia, Gait, Hemiplegic
The Effect of Robot-assisted Walking Training on Hemiplegic Individuals
The aim of this study is to compare the effects of robotic rehabilitation on balance, body control, mobility, spasticity, motor function and depression compared to traditional therapy in individuals with chronic stroke.
- Conditions
- Hemiplegia, Gait, Hemiplegic, Motor Function, Balance; Distorted
- Trial name
- NCT05492097
- Testing
- Exercise Therapy, Exercise Therapy and Robotic Walking Training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Medipol University
Stroke, Muscle Spasticity
The Effectiveness of Early Botulinum Toxin A Injection for Lower Limbs Spasticity in Subacute Stroke Adults
Botulinum toxin A (BoNT-A) injections are widely used to treat spasticity after stroke. Although this treatment is effective on muscle tone improvement, its effect on gait and ability of daily living on early stage of stroke…
- Trial name
- NCT02505802
- Testing
- BoNT-A injection
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sir Run Run Shaw Hospital
Neurologic Disorder, Spastic Hemiplegia
Proximal Lower Limb Intramuscular Block : Effects on Hemiparetic Gait
To assess feasability, tolerance of anesthesic intramuscular motor block. To study immediate effects on differents muscles : gluteus maximus, rectus femoris in a hemiparetic population (over 15 days) To precise the role of the…
- Conditions
- Neurologic Disorder, Spastic Hemiplegia, Gait, Hemiplegic, Block
- Trial name
- ProxiBlock (NCT05519592)
- Testing
- Ropivacaine injection, Sodium Chloride Injection
- Volunteers
- 30 people
- Sponsor
- Henri Mondor University Hospital
Spastic Gait, Fall Due to Failure of Support
Short Effects of a Rehabilitation Session on Gait in Patients With CNS
The aim of the study is to evaluate the short effects of a two rehabilitation session commonly performed in physical therapy, 1. muscle strengthening of the lower limbs and 2.
- Conditions
- Spastic Gait, Fall Due to Failure of Support, Fatigue
- Trial name
- NCT01807247
- Testing
- Intensive lower limbs muscles strengthening
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre d'Investigation Clinique et Technologique 805
Cerebral Palsy, Spastic
Whole Body Vibration in Children With Cerebral Palsy
Some positive effects of whole body vibration applications in reducing spasticity, improving walking ability, and increasing walking speed have been reported in children with CP, but the evidence is not strong enough.
- Trial name
- CP (NCT05636241)
- Testing
- conventional physiotherapy program, whole body vibration training program
- Where
- Turkey (Türkiye)
- Volunteers
- 13 people
- Sponsor
- Kutahya Health Sciences University
Neurodevelopmental Disorders, Neurodevelopmental Disorders (NDD)
Intensive Multimodal Neurorehabilitation Targeting Neuroplasticity in Pediatric Neurodevelopmental and Chromosomal Disorders
This observational study evaluates functional and developmental outcomes in pediatric participants undergoing a two week intensive multimodal neurorehabilitation program.
- Conditions
- Neurodevelopmental Disorders, Neurodevelopmental Disorders (NDD), Neurodevelopmental Disorders and Developmental Abnormalities, Developmental Delay (Disorder)
- Trial name
- GEN-HOPE (NCT07493096)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Healing Hope International
Hereditary Spastic Paraplegia
Robot-assisted Walking Treatment in Hereditary Spastic Paraplegia (HSP)
Patients will undergo a combined rehabilitation treatment consisting of 15 sessions on Lokomat and 15 sessions of physical therapy over three weeks for a total of 30 sessions. Two sessions/day for 5 days a week.
- Trial name
- NCT06728787
- Testing
- Robot-Assisted Gait Training
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- IRCCS Eugenio Medea
Neuromuscular Diseases, Obesity (Disorder)
Gait Analysis Parameter and Upper Limb Evaluation in Adult Patients With Neurological or Metabolic Pathology
The ActiLiège-Adult study is a prospective, longitudinal, observational study designed to collect natural history data on adult patients with neurological or metabolic diseases affecting movement.
- Conditions
- Neuromuscular Diseases, Obesity (Disorder), Myotonic Dystrophy 1, Myasthenic Syndrome
- Trial name
- Acti-Adult (NCT07136844)
- Testing
- Syde, Dynamometric measurements of muscle strength, The 6-minute walk test (6MWT)
- Where
- Belgium
- Volunteers
- 300 people
- Sponsor
- Centre Hospitalier Universitaire de Liege
Cerebral Palsy, Spastic Diplegia
Walking Inclined Plane
The adaptations in kinematics and muscle activity, investigated by 3D gait analysis and dynamic electromyography recordings, will be studied in children with bilateral spastic cerebral palsy during level walking, and before and…
- Trial name
- NCT02988557
- Testing
- walking on a treadmill with a sloped surface, treadmill
- Where
- France
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Spinal Cord Injuries, Stroke
Muscle-tendon Interaction in the Spastic Sural Triceps During Gait
This project aims to study the mechanical behavior of the muscle-tendon unit (MTU) of the gastrocnemius medialis (GM) and the Achilles tendon (AT) in post-stroke and spinal cord injured (SCI) patients compared to a healthy…
- Trial name
- GEcho (NCT06474117)
- Testing
- Gait analysis coupled with ultrasound, Isokinetic dynamometer with simultaneous ultrasound
- Where
- France
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Spastic Diplegia Cerebral Palsy
Effect of Spring Gravity Bar on Gait Pattern in Children With Spastic Diplegia
The purpose of the study is to determine the effect of spring gravity bar on gait pattern in children with spastic diplegia
- Trial name
- NCT04628247
- Testing
- Spring gravity bar
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Cerebral Palsy, Diplegia, Spastic
Validity of the Kinematic Classification of Gait in Diplegic Children With Cerebral Palsy (CP)
In recent years Ferrari et al. proposed a new classification of gait in diplegic children with spastic diplegia that describes four different patterns of gait by analyzing the strategies that each children adopts to need his/her…
- Trial name
- NCT01158833
- Testing
- classification of gait in diplegic children with CP
- Where
- Italy
- Volunteers
- 86 people
- Sponsor
- University of Modena and Reggio Emilia
Gait Disorders in Children, Cerebral Palsy Spastic Diplegia
Comparison of Walking Parameters Between Idiopathic Toe Walking and Independent Walking Diparetic Cerebral Palsy
The aim of the observational study is to compare static, kinematic and kinetic parameters with normal gait parameters in cases with Idiopathic toe walking (ITW) and Diparetic Cerebral Palsy (DCP) who have Gross Motor Function…
- Trial name
- NCT06142721
- Testing
- 3D Gait Analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Biruni University
Cerebral Palsy
A Pilot Study of the Effect of Botulinum Toxin Type a (Dysport®, Abobotulinum Toxin A) Injection on Changes in Musculotendinous Length and Dynamics of Hamstring Muscles During Gait in Children With Spastic Cerebral Palsy Walking With Excessive Knee Flexion
This is a longitudinal, prospective, and open-label interventional study in a single center. We will investigate the effect of single injection in each patient.
- Trial name
- NCT02917967
- Testing
- Botulinum toxin injection
- Where
- South Korea
- Volunteers
- 31 people
- Sponsor
- Yonsei University
Cerebral Palsy, Spastic, Gait Disorders, Neurologic
Reliability of a Body-worn Sensor System for Gait Analysis in Children With CP
Cerebral palsy (CP) is caused by a non-progressive injury in the developing brain, which leads to problems in functional mobility, posture, neuro musculoskeletal functions and gait.
- Trial name
- NCT04240275
- Testing
- Reliability of the G-Walk device in children with Cerebral Palsy
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Gazi University
Stroke, Spasticity, Muscle
Impact of Muscular Fatigability on Spastic Co-contractions After Stroke Patients
This study evaluates the effects of an isokinetic fatigue protocol of the quadriceps on the amount of co-contractions of this last with the hamstrings during a maximal isometric flexion movement in hemiparetic stroke patients.
- Conditions
- Stroke, Spasticity, Muscle, Muscle Fatigue, Gait, Hemiplegic
- Trial name
- COCON (NCT03342820)
- Testing
- Muscle fatigue
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Lille