Clinical trials: Spasticity as Sequela of Stroke
Spasticity as Sequela of Stroke, Stroke
Prevalence of Postural Patterns of Upper Extremity.
A high number of patient with stroke develops spasticity of the upper extremity, this clinical sign of damage of 1 motoneuro (MN), causes postures and patterns of abnormal movement, due to the hyperexcitability of the MN and the…
- Conditions
- Spasticity as Sequela of Stroke, Stroke, Upper Extremity Paresis
- Trial name
- Patterns (NCT03588832)
- Testing
- Evaluation Upper Extremity patterns.
- Where
- Chile
- Volunteers
- 600 people
- Sponsor
- Universidad de La Frontera
Spasticity as Sequela of Stroke
Home Based Electrical Stimulation on Post-stroke Lower Limb Tightness.
Spasticity is a common complication post stroke. Post-stroke spasticity along with weakness and lack of coordination result in gait abnormalities and functional limitations.
- Trial name
- NCT04932668
- Testing
- Feasibility and Impact of Home-based Electrical Stimulation Program
- Where
- Malaysia
- Volunteers
- 20 people
- Sponsor
- University of Malaya
Spasticity as Sequela of Stroke, Nerve Transfers
Nerve Transfers in Post-stroke Spasticity
Stroke is nowadays a leading cause of disability with devastating sequelae. Upper limb spasticity is one of them. Nevertheless, not all the muscles are equally affected, as some may turn spastic or paretic and other remain…
- Trial name
- NCT04437056
- Testing
- Cognitive nerve transfers to spastic upper extremity muscles in stroke patients
- Where
- Austria
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Stroke, Cerebrovascular Accident (CVA)
The Role of Trans-spinal Direct Current Stimulation (tsDCS) in Treating Patients With Hand Spasticity After Stroke
The purpose of this study is to evaluate if 5 consecutive sessions of PathMaker anodal DoubleStim treatment, which combines non-invasive stimulation of the spinal cord (tsDCS- trans-spinal direct current stimulation) and of the…
- Conditions
- Stroke, Cerebrovascular Accident (CVA), Hemiparesis, Spasticity as Sequela of Stroke
- Trial name
- NCT03080454
- Testing
- anodal Doublestim
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Northwell Health
Aromatherapy, Spasticity as Sequela of Stroke
Aromatherapy on Upper Limb Spasticity on Stroke Survivors
This study employed a double-arm, pre- and post-test design. Stroke survivors aged 65 or above with post-stroke upper limbs spasticity were recruited from two RCHEs in Hong Kong between February and June 2025, and were divided…
- Trial name
- NCT07286825
- Testing
- massage oil with a mixture of sweet marjoram essential oil and fractionated coconut organic carrier oil, plain fractionated coconut organic carrier oil
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- Hong Kong Metropolitan University
Stroke, Hemiplegia Following Ischemic Stroke
Improving STEP in Stroke Patients
Stroke is the leading cause of acquired disability in adults. Stroke causes death in 10% of patients, disability and functional handicap in 60% of cases.
- Conditions
- Stroke, Hemiplegia Following Ischemic Stroke, Disability Physical, Spasticity as Sequela of Stroke
- Trial name
- I-STEP (NCT07403149)
- Testing
- REMARCHE® shoes
- Volunteers
- 58 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Spasticity as Sequela of Stroke, Spastic Cerebral Palsy
Radiosurgery Treatment for Spasticity Associated With Stroke, SCI & Cerebral Palsy
A scientific study is being done to test a special treatment for people who have spasticity or tight muscles. This treatment is called "stereotactic radiosurgery dorsal rhizotomy." It uses very accurate beams of radiation to…
- Conditions
- Spasticity as Sequela of Stroke, Spastic Cerebral Palsy, Spasticity, Muscle
- Trial name
- SPASM (NCT06070233)
- Testing
- stereotactic radiosurgery (SRS) dorsal root rhizotomy radiomodulation
- Where
- 2 sites in United States
- Volunteers
- 22 people
- Sponsor
- Ohio State University
Spasticity as Sequela of Stroke
Anti-Spastic Splint With Focal Muscle Vibration for Stroke Hand Spasticity
Title: The Effect of Vibrating Splint on Hand Function After Stroke Summary: This study aims to investigate the effectiveness of a vibrating splint in improving hand function and reducing spasticity among individuals who have…
- Trial name
- NCT06358976
- Testing
- Vibration plus anti-spastic hand splint, Anti-spastic hand splint, Vibration
- Where
- Palestinian Territories
- Volunteers
- 48 people
- Sponsor
- Arab American University (Palestine)
Stroke, Hemiplegia
H-reflex Measurement in Hemiplegic Stroke Patients
As human beings live longer, geriatric disease develop, one of which was stroke whose prevalence elevated by aging. Increased spasticity is a common symptom after stroke and may hinder patient from rehabilitation.
- Conditions
- Stroke, Hemiplegia, Spasticity as Sequela of Stroke
- Trial name
- NCT04977531
- Volunteers
- 60 people
- Sponsor
- Heng-Yi, Shen
Muscle Spasticity, Stroke Sequelae
Comparison of Two Botox Injection Techniques to Improve Gait
According to our hypothesis, the use of HD-EMG shall allow an accurate localization of the innervations zones of the muscles, offering a better complement to the methodology applied so far to define the botulinum neurotoxin…
- Conditions
- Muscle Spasticity, Stroke Sequelae, Spasticity as Sequela of Stroke, Gait Disorders, Neurologic
- Trial name
- NCT07124806
- Testing
- Botulinum toxin guided by ultrasonography and anatomical references, Botulinum neurotoxin guided by ultrasonography and in vivo location of innervation zones guided by high-density electromyography
- Where
- 2 sites in Chile
- Volunteers
- 18 people
- Sponsor
- Universidad de los Andes, Chile
Spasticity as Sequela of Stroke
Cryoneurolysis for Spasticity Treatment: Long-term Clinical Outcomes and Mechanisms in the Central Nervous System
Spasticity can make regular daily activities difficult or impossible. Cryoneurolysis is a new technique to treat spasticity that is currently being tested.
- Trial name
- NCT06958289
- Testing
- Cryoneurolysis
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Sue Peters
Spasticity as Sequela of Stroke
Dose-response Relationship of Botullinum Toxin (DWP 450) for Finger Flexor Spasticity
Study Design: Randomized Single Blind Study Objective: To determine the dose relationship of DWP 450 for finger flexor spasticity Subjects: 78 patients with upper extremity spasticity after CVA Inclusion criteria: Patient who…
- Trial name
- NCT03517319
- Testing
- Normal Saline 0.9% 1.2 ml, Clostridium Botulinum Toxin Type A (Nabota, DWP 450) 15 U, Clostridium Botulinum Toxin Type A (Nabota, DWP 450) 30 U
- Where
- South Korea
- Volunteers
- 78 people
- Sponsor
- Seoul National University Hospital
Chronic Pain, Spasticity as Sequela of Stroke
Closed Loop Spinal Cord Stimulation for Neuromodulation of Upper Motor Neuron Lesion Spasticity
Spasticity is characterized by increased muscle tension and is a classic consequence of upper motor neuron (UMN) damage in the central nervous system, such as from stroke or trauma.
- Conditions
- Chronic Pain, Spasticity as Sequela of Stroke, Upper Motor Neuron Lesion
- Trial name
- CLONUS (NCT06384170)
- Testing
- Spinal Cord Stimulation- Closed loop
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Spasticity as Sequela of Stroke
Repetitive Transcranial Magnetic Stimulation in Post Stroke Upper Limb Spasticity
The reticulospinal pathway (RSP) is at the center of spasticity mechanism. The RSP indirectly synapses with motor neurons via interneurons in the ventromedial intermediate zone in both halves of the spinal cord, and directly…
- Trial name
- NCT04063995
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people
- Sponsor
- Izmir Katip Celebi University
Spasticity as Sequela of Stroke
EXOPULSE Mollii Suit, Motor Function & Stroke (EXOSTROKE)
Spasticity is a common and debilitating complication in neurological conditions such as multiple sclerosis, cerebral palsy, and stroke.
- Trial name
- EXOSTROKE (NCT06702163)
- Testing
- EXOPULSE MOLLII SUIT (active)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Institut De La Colonne Vertebrale Et Des Neurosciences
Spasticity as Sequela of Stroke, Gait, Hemiplegic
Motor Imagery Technique on Lower Limb Function Among Stroke Patients.
To determine the effects of motor imagery technique on lower limb function among stroke patient. To determine the effects of motor imagery technique on lower limb spasticity among stroke patients.
- Conditions
- Spasticity as Sequela of Stroke, Gait, Hemiplegic, Quality of Life
- Trial name
- NCT04707755
- Testing
- Motor imagery technique, Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Stroke, Spasticity as Sequela of Stroke
Effect of ESWT Applied After Botulinum Toxin Injection on Ankle Spasticity in Stroke Patients.
Stroke is the second most common cause of death and the third most important cause of disability worldwide, with an annual death rate of 5.5 million.
- Trial name
- NCT06126523
- Testing
- Radial Extracorporeal Shock Wave Therapy ONCE, Radial Extracorporeal Shock Wave Therapy TWİCE
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Saglik Bilimleri Universitesi
Stroke, Spasticity as Sequela of Stroke
Robotic Hand Rehabilitation
The performance of activities of daily living (ADL) depends to a large extent on the functionality of the upper limb and hand. Stroke is the leading cause of disability worldwide, with a significant individual, family and…
- Conditions
- Stroke, Spasticity as Sequela of Stroke, Upper Limb
- Trial name
- RoHa-S (NCT05983822)
- Testing
- Technological Group, Conventional Treatment
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Stroke, Hemiparesis
Recovery of Motor Skills With the Use of Artificial Intelligence and Computer Vision
To investigate the impact of algorithms utilizing artificial intelligence technology and computer vision on the recovery of motor functions within the context of rehabilitation practice for patients who have experienced a…
- Conditions
- Stroke, Hemiparesis, Spasticity as Sequela of Stroke, Dysmetria
- Trial name
- NCT06183970
- Testing
- AssistI patients, Habilect patients
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Federal Center of Cerebrovascular Pathology and Stroke, Russian Federation Ministry of Health
Brain Injuries, Disorder of Consciousness
Long Term Effects of Soft Splints on Stroke Patients and Patients With Disorders of Consciousness
The purpose of this study is to assess the effects on upper limb spasticity of soft splints worn during three weeks three hours a day by patients with stroke or disorders of consciousness.
- Conditions
- Brain Injuries, Disorder of Consciousness, Stroke, Spasticity as Sequela of Stroke
- Trial name
- NCT03008486
- Testing
- Real soft splint (6 cm)
- Where
- Belgium
- Volunteers
- 12 people
- Sponsor
- Géraldine Martens