Clinical trials: Specificity
Sickle Cell Anemia
The Montreal Cognitive Assessment.Test in Adults With Sickle Cell Disease
This study will assess the performances of the Montreal Cognitive Assessment (MoCA) to screen for cognitive impairment in adults with sickle cell anemia.
- Trial name
- EvaCAD (NCT05347043)
- Testing
- Montreal cognitive assessment
- Where
- France
- Volunteers
- 65 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Asthma
A Comparative Bronchial Provocation Study With Mannitol and Methacolinie in a Korean Population
Asthmatic patients and non-asthmatic controls were recruited prospectively from four referral hospitals in Korea. Participants were challenged with each of methacholine and mannitol inhalation on different days.
- Trial name
- NCT02104284
- Testing
- methacholine and mannitol bronchial challenge tests
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- BL&H Co., Ltd
Lichen Planus
Cellular and Molecular Biomarkers in Patients With Lichen Planus
Lichen planus (LP) is a chronic inflammatory disease of unknown aetiology, affecting the skin and mucous membranes, characterised by a CD8+ cytotoxic T-cell infiltrate, associated with epithelial cell death and disruption of the…
- Trial name
- HELP (NCT06451744)
- Testing
- Blood samples collection, Skin or mucous membrane brushing, Skin or mucous membrane biopsy
- Where
- 6 sites in France
- Volunteers
- 70 people
- Sponsor
- Institut Pasteur
MCI
Accexible Speech Analysis for MCI Detection and Monitoring in Colombia
Mild Cognitive Impairment (MCI) is frequently underdiagnosed due to its subtle clinical presentation. This study evaluates the diagnostic performance of AcceXible, a speech analysis-based machine learning platform, compared to…
- Trial name
- NCT07553117
- Testing
- Accexible
- Where
- Colombia
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Accexible
Tuberculosis, Psoriasis
Sensitivity and Specificity of QuantiFeron -TB Gold Test (QFT-G)in Patients With Psoriasis
The purpose of this study is to determine the level of agreement between QuantiFeron -TB Gold test (QFT-G)and Tubeculin skin test (TST)for screening of latent tuberculosis in patients suffering from psoriasis.
- Trial name
- NCT01223976
- Testing
- Tuberculin skin test and Quantiferon -TB Gold test
- Where
- Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Chronic Osteomyelitis
Detection of Osteomyelitis Using High Resolution Ultrasound
The purpose of this study is to establish the sensitivity of HRUS as compared to MRI for the diagnosis of osteomyelitis in chronic wound patients; and to determine the specificity of HRUS as compared to pathologic and…
- Trial name
- NCT02198755
- Testing
- Hitachi-Aloka Noblus ultrasound scanner, Magnetic Resonance Imaging (MRI)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Calvary Hospital, Bronx, NY
Dementia, Memory Disorders
Identifying Patients With Dementia in Primary Care
Veterans who completed GEMS-Phase 1 will be asked to participate in GEMS-Phase 2 to determine the accuracy of methods used to assess mild memory problems.
- Trial name
- GEMS (NCT00289471)
- Testing
- No intervention delivered.
- Where
- United States
- Volunteers
- 630 people
- Sponsor
- US Department of Veterans Affairs
Acute Appendicitis
Sensitivity and Specificity of the Alvarado Score for the Timely Differential Diagnosis of Acute Appendicitis in Samoa
Retrospective clinical data review design of all patients admitted to the Tupua Tamasese Meaole Hospital Surgical Unit for AA from January 2015 to December 2016.
- Trial name
- NCT05168410
- Testing
- Alvarado Score
- Volunteers
- 225 people
- Sponsor
- Dr Annette Kaspar
Solid Tumor, Adult
NeoTIL in Advanced Solid Tumors
Single center, single arm pilot trial to test the feasibility, safety and efficacy of NeoTIL-ACT combined with low-dose irradiation (LDI) in patients with advanced, recurrent or metastatic solid tumors.
- Trial name
- NCT04643574
- Testing
- NeoTIL, Cyclophosphamide, Fludarabine
- Where
- Switzerland
- Volunteers
- 42 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Syphilis Infection, Syphilis
Evaluation of the Sensitivity, Specificity, and Utility of the Reveal® TP (Syphilis) Antibody POCT
This study is to test the Reveal® TP (Syphilis) antibody POCT (MedMira, Inc., Halifax, Nova Scotia) for its performance in an urban STI clinic in Vancouver, British Columbia and compare its performance in parallel with the usual…
- Conditions
- Syphilis Infection, Syphilis, Early Syphilis, Symptomatic
- Trial name
- NCT05831098
- Testing
- Reveal TP (Syphilis) Antibody Test
- Where
- Canada
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- MedMira Laboratories Inc.
Hepatitis B, Hepatitis B Infection
A Study to Evaluate Diagnostic Sensitivity and Specificity of iStatis HBsAg Test at the Point-Of-Care Sites
A prospective cross-sectional study in which surgically non-invasive sample-taking is done only for the purpose of the study. Capillary (fingerstick) whole blood and EDTA venipuncture whole blood are collected by a healthcare…
- Trial name
- NCT06368466
- Testing
- iStatis HBsAg Test
- Where
- Australia
- Volunteers
- 175 people
- Sponsor
- bioLytical Laboratories
Tuberculosis
Specificity Trial of the Recombinant Tuberculosis Allergen in BCG Vaccinated Healthy Volunteers
The aim of this study is to test the recombinant tuberculosis skin test in the previously BCG vaccinated healthy adults with low risk of TB development, to determine the test specificity.
- Trial name
- NCT05203068
- Testing
- Recombinant tuberculosis allergen (RTA)
- Where
- Russia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Medical Research Center of Phthisiopulmonology and Infectious Diseases
Allergy, Hypersensitivity, Immediate
Head-to-Head Comparison Study Between Different FDA Registered Allergy Skin Test Applicators
This clinical study, titled "Head-to-Head Comparison Study between Different FDA Registered Allergy Skin Test Applicators," aims to compare the reliability and clinical performance of three skin prick test (SPT) devices…
- Conditions
- Allergy, Hypersensitivity, Immediate, Ig-E Mediated Food
- Trial name
- NCT07400718
- Testing
- AllerTest-10 Multi-Head Skin Test Device, Skintestor OMNI Multi-Head Skin Test Device, Multi-Test II Multi-Head Skin Test Device
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- QHSLab, Inc.
African Trypanosomiasis, African; Trypanosomiasis, West
Diagnostic Tools for Human African Trypanosomiasis Elimination and Clinical Trials: Early Test-of-cure
The study validates the diagnostic performance of cerebrospinal fluid neopterin quantification and of blood and cerebrospinal fluid trypanosomal spliced leader RNA detection for assessing outcome after treatment of human African…
- Conditions
- African Trypanosomiasis, African; Trypanosomiasis, West, Sleeping Sickness; West African, Trypanosoma Brucei Gambiense; Infection
- Trial name
- DiTECT-WP4 (NCT03112655)
- Testing
- RNA and neopterin detection
- Where
- Democratic Republic of the Congo
- Volunteers
- 88 people
- Sponsor
- Institut de Recherche pour le Developpement
Lung Cancer, Breast Cancer
Non Invasive Detection of Lung and Breast Cancer by Odor Signature
The investigators have developed an early detection solution for lung and breast cancer. A system which can distinguish between different medical odors based on biosensors.
- Trial name
- NCT02195076
- Testing
- non-invasive detection of cancer odor
- Where
- Israel
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- BioSense Medical LTD
Mild Dysplasia of Esophagus, Moderate Dysplasia of Esophagus
Performance of White Light, NBI and Iodine Staining Endoscopy in the Diagnosis of Esophageal Lesions
The investigators aim to evaluate the performance of Narrow Band Imaging (NBI) endoscopy in Esophageal Squamous Cell Carcinoma (ESCC) screening, as compared to the currently used White Light Endoscopy (WLE) and Lugol's Iodine…
- Conditions
- Mild Dysplasia of Esophagus, Moderate Dysplasia of Esophagus, Severe Dysplasia of Esophagus, Carcinoma in Situ of Esophagus
- Trial name
- NCT04170257
- Testing
- Endoscopic examination using white light, NBI and iodine staining
- Where
- 5 sites in China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Peking University Cancer Hospital & Institute
Allergy, Allergic Asthma
abioSCOPE IgE Assay to Aid in the Diagnosis of Allergies
This is a multicenter, prospective, observational study designed to determine the clinical sensitivity and specificity of the Abionic IVD CAPSULE Allergic Asthma panel performed on Abionic's abioSCOPE device using K3-EDTA…
- Conditions
- Allergy, Allergic Asthma, Allergy to Cats, Allergy to House Dust
- Trial name
- NCT04442932
- Testing
- Blood Collection
- Where
- 5 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Abionic SA
Blood Pressure
Validation of Pulse Waveform Analysis-based Continuous Noninvasive Blood Pressure Measurement Sensor
The study aims to define the sensitivity and specificity of a novel continuous noninvasive blood pressure monitor.
- Trial name
- NCT02357511
- Testing
- Study Monitor used
- Where
- Finland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
Spinal Deformity, Spinal Fractures
Posterior Ligament Complex Assessment Without Magnetic Resonance Image in Thoracolumbar Fractures
The objective of this investigation is to confirm the results obtained in a pilot study showing that certain radiological parameters based on computed tomography (CT) scans seem to reliably detect posterior ligament complex (PLC)…
- Conditions
- Spinal Deformity, Spinal Fractures, Spinal Injuries, Kyphosis
- Trial name
- PAM (NCT02950532)
- Testing
- Retrospective radiological evaluation
- Where
- 5 sites in China, Egypt and 3 more
- Volunteers
- 60 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Phobia, Social
Dysfunctional Attention Processes in Fear of Blushing: Specificity and Changeability
Blushing is associated with a heightened self-focused attention. In our study we are interested if this self-focused attention can be shown experimentally and if it can be changed by therapy and training.
- Trial name
- NCT00751465
- Testing
- Task Concentration Training, Standard CBT
- Where
- Germany
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Technische Universität Dresden