Clinical trials: Specificity
Cancer, Malignancy
Non-Invasive Neurosensory Testing For Chemotherapy-Induced Peripheral Neuropathy
Problem: A significant proportion of patients with cancer experience symptoms of sensory, motor or autonomic nerve damage from chemotherapy known as chemotherapy-induced peripheral neuropathy (CIPN).
- Conditions
- Cancer, Malignancy, Malignant Neoplasm, Neuropathy
- Trial name
- NCT03909464
- Testing
- Neurosensory testing with Pressure-Specified Sensory Device
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Azotemia, Renal Insufficiency, Chronic
Sensitivity and Specificity of NGAL in an Emergency Room Population
Hypothesis: In patients that present to an urban emergency room, a single urine neutrophil gelatinase-associated lipocalin (NGAL) measurement can classify their kidney disease as stable chronic kidney disease, acute tubular…
- Conditions
- Azotemia, Renal Insufficiency, Chronic, Renal Failure, Acute, Hydronephrosis
- Trial name
- NCT00786708
- Where
- 3 sites in United States, Germany
- Volunteers
- 2,304 people
- Sponsor
- Columbia University
Post-natal Cytogenetics
Method Comparison and Clinical Specificity Study: Evaluation of the Infinium HD Cytogenetic Abnormality Test
The study will determine the performance of the Infinium HD Test. The primary objective of the study is to assess the performance of the Infinium HD Test using banked DNA samples extracted from whole blood patient samples derived…
- Trial name
- NCT01426308
- Where
- 3 sites in United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Illumina, Inc.
Sleep Apnea, Metabolic Syndrome
Improving the STOP-Bang Screening Questionnaire for Patients With Sleep Apnea
The study is being conducted to test the ability of a simple questionnaire to detect mild, moderate or severe obstructive sleep apnea.
- Trial name
- NCT01610648
- Where
- United States
- Volunteers
- 258 people
- Sponsor
- Tufts Medical Center
PREMATURE RUPTURE OF MEMBRANES
AL-SENSE 1-Step - Determination of Product Specificity
Clinical diagnosis of amniotic fluid leak will be determined, according the hospital standard procedure, using pooling test and/or sterile speculum examination and /or pH test, and AmniSure, N-Dia, Inc.
- Trial name
- ROM (NCT01804348)
- Testing
- AL-SENSE 1-Step
- Where
- Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Common Sense
Dry Eye
RPS InflammaDry Detector™ to Determine MMP-9 Levels in Tears
The RPS InflammaDry Detector™ is intended to detect elevated MMP-9 in human tears to aid in the diagnosis of patients with signs or symptoms of dry eye disease, in conjunction with other methods of clinical evaluation.
- Trial name
- NCT01313351
- Testing
- RPS InflammaDry Detector™
- Where
- 8 sites in United States
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- Rapid Pathogen Screening
Chest Trauma
Senstivity and Specificity of Lung Ultrasound for Early Detection of ARDS in Patients With Chest Trauma
The aim of this study is to evaluate the accuracy, sensitivity and specificity of lung ultrasound in early detection of ARDS and Pneumonia in comparison to CT chest in patients with chest trauma.
- Trial name
- NCT06078254
- Testing
- ULTRASOUND
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Electroencephalography, Refractory Epilepsy
Clinical Utility of Automated Electric Source Imaging in Presurgical Evaluation
Electrical source imaging is part of the presurgical evaluation of patients with drug-resistant focal epilepsy. The software packages that will be used in this study have Declaration of Conformity within the European Economic…
- Conditions
- Electroencephalography, Refractory Epilepsy, Brain Imaging, Surgery
- Trial name
- PROMAESIS (NCT04218812)
- Testing
- No electrical source imaging (ESI), Automated electrical source imaging (ESI)
- Where
- 12 sites in Austria, Czechia and 6 more
- Volunteers
- 250 people
- Sponsor
- Sándor Beniczky
Peripheral Nerve Block
Determination of the Sensitivity, Specificity & Receiver Operating Characteristic of Nerve Stimulation Receptor as a Decision-making Tool During US Guided PNB
Although the superiority of ultrasound guidance over neurostimulation (NS) has been demonstrated, it has its limits, namely when used for a deeper block (device limits) or if used by a less experienced operator (ability to…
- Trial name
- NCT05190302
- Where
- Canada
- Volunteers
- 115 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Immune Thrombocytopenic Purpura
A Safety Study of Intravenous Immunoglobulin in Patients With Chronic Immune Thrombocytopenic Purpura (ITP)
It is known that intravenous immunoglobulins can induce hemolysis, but the mechanism is not known in detail. The primary objective of this study was to investigate the specificity of antigens on red blood cells in patients with…
- Trial name
- NCT01390649
- Testing
- IgPro10
- Where
- 17 sites in Bulgaria, Romania and 1 more
- Volunteers
- 57 people
- Sponsor
- CSL Behring
To Evaluate the Sensitivity and Specificity of a Test Kit in Hong Kong
The Diagnostic Accuracy of Using Faecal-DNA Test (COLOSAFE) for Colorectal Cancer Screening
To evaluate the sensitivity and specificity of the test kit "COLOSAFE' in Hong Kong
- Trial name
- NCT04030637
- Where
- Hong Kong
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Syphilis, Treponema Pallidum
A Cross-sectional Investigational Study to Evaluate the Sensitivity, Specificity, and Utility of the MedMira Inc. Multiplo® Complete Syphilis (TP/nTP) Antibody Test (POCT) to Diagnose Infectious Syphilis in Participants Attending the Sexual Health Clinic in Ottawa, Ontario.
Due to the recent resurgence of infectious syphilis in Canada and the changing epidemiology of the disease to involve heterosexuals and females of child bearing age leading to a record number of congenital syphilis cases and…
- Trial name
- NCT06586905
- Testing
- Medical Device
- Where
- Canada
- Volunteers
- 1,300 people, healthy volunteers welcome
- Sponsor
- MedMira Laboratories Inc.
Medication Review
APHID- Primary Care Accuracy Study
We are studying patients' abilities to correctly identify the prescription medications they are taking. We are interested in understanding what tools will help patients correctly identify their medications.
- Trial name
- NCT02135731
- Testing
- Medication review software with pictures
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Blake Lesselroth
Parkinson Disease
The Sensitivity and Specificity of Canine Detection of Parkinson's Disease
People sometimes report that their relatives who have been diagnosed with Parkinson's disease (PD) have a unique smell. A previous study has demonstrated that PD patients do have smell that is different from that of healthy…
- Trial name
- NCT04613531
- Where
- China
- Volunteers
- 1,198 people
- Sponsor
- Central South University
Parkinson's Disease
Characterizing the Specificity and Stability of Local Field Potentials in the Globus Pallidus Internus of Patients Undergoing Deep Brain Stimulation for Parkinson's Disease
Deep brain stimulation for Parkinson's disease is a well established therapy. Current practice requires tedious adjustment of stimulation settings based on frequent patient assessments.
- Trial name
- NCT02438033
- Testing
- Medtronic Activa PC+S Sensing Deep Brain Stimulator Generator
- Sponsor
- Nader Pouratian
Myocardial Infarction, Acute
Biomarkers in Patients Hospitalized With Suspected Acute Myocardial Infarction
The concentration of troponins in plasma is used for diagnosing acute myocardial infarction. Different types of heart-specific troponins can be measured and with different analytical methods.
- Trial name
- BIOMAC (NCT04167904)
- Where
- Norway
- Volunteers
- 4,446 people
- Sponsor
- St. Olavs Hospital
Intervertebral Disc Displacement, Intervertebral Disc Degeneration
Lumbar Disc Space Height in Young Disc Herniation and Degeneration Patients
As low back pain (LBP) imposes a heavy socioeconomic burden, early detection of pathologic intervertebral disc change in young adults holds high clinical relevance as a common structural cause of LBP.
- Conditions
- Intervertebral Disc Displacement, Intervertebral Disc Degeneration, Low Back Pain
- Trial name
- NCT02351206
- Testing
- x-ray, MRI
- Volunteers
- 389 people, healthy volunteers welcome
- Sponsor
- Jaseng Hospital of Korean Medicine
Septic Shock, Fluid Reponsiveness
This Study Compares Two Noninvasive Dynamic Tools: Lung Ultrasound and Transthoracic Echocardiography Using LVOT VTI. It Aims to Measure the Sensitivity and Specificity of LUS in Guiding Fluid Resuscitation and Early Detection of Fluid Responsiveness and to Prevent Volume Overload
Reliability of the LVOT-VTI versus lung ultrasonography for early detection of fluid intolerance during fluid resuscitation of septic patients.
- Trial name
- lvotvti (NCT07797751)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Appendicitis, Child
CT Scan Using IV Contrast Alone for Pediatric Appendicitis
Computed tomography (CT) scan using intravenous contrast (CT IV) as the sole type of contrast material, was studied as one method of evaluating children with suspected appendicitis.
- Conditions
- Appendicitis, Child, Contrast Media
- Trial name
- NCT00716703
- Testing
- CT Scan using IV contrast alone
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Rochester
Metabolic Acidosis
A Study on Bedside Formate Assay as a Diagnostic Tool in Methanol Poisoning
Methanol poisoning is a serious issue, particularly in low- and middle-income countries (LMICs), where outbreaks can devastate communities.
- Trial name
- NCT06881641
- Where
- 6 sites in Bangladesh, India
- Volunteers
- 6,120 people
- Sponsor
- University of Edinburgh