Clinical trials: Specificity
Psychotic Disorders, Schizophrenia
The Topical Niacin Skin Flush Test in First Episode Psychosis
The purpose of this study is to gather normative data from healthy adults and to determine a sensitive and specific cut-off value for responders and non-responders to the Niacin Skin Flush Test in a sample of first episode…
- Trial name
- NCT01324297
- Testing
- skin test
- Where
- Canada
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Tuberculosis
Sensitivity and Specificity of Xpert MTB/RIF Ultra
To estimate diagnostic accuracy of Xpert Ultra and Xpert MTB/RIF for extrapulmonary tuberculosis and rifampicin resistance in adults suspected to be infected with mycobacterium tuberculosis.
- Trial name
- NCT06058065
- Volunteers
- 200 people
- Sponsor
- Assiut University
Sepsis
Sensitivity and Specificity of Leucocytes Profiling Versus Platelet Indices in Prediction of Clinical Outcome for Candidates With Sepsis. A Bi-centric Observational Clinical Trial
Leucocyte subpopulation and platelet indices analysis can predict clinical outcome
- Trial name
- NCT06612307
- Where
- Egypt
- Volunteers
- 422 people
- Sponsor
- Minia University
Head And Neck Cancer, Oropharynx Cancer
OraTest in Combination With Visual Examination and Visual Examination Alone
Primary Objectives: 1. To assess the ratio in sensitivities of OraTest® in combination with visual examination versus visual examination alone in the detection of serious pathology defined as severe dysplasia, CIS, or cancer of…
- Trial name
- NCT00537199
- Testing
- Visual Examination, OraTest
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Healthy
In-Vivo Bleeding Volume Test for Platelet-Aspirin Interaction
Purpose of the present research project is to study a new in-vivo test for abnormal platelet function and to study the effect of certain drugs on clinical bleeding.
- Trial name
- Aspirin-BVT (NCT01047722)
- Testing
- Aspirin ingestion followed by doing a Bleeding Volume Test
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Klein, Jeffrey A., M.D.
Pediatric Ankle Fracture
Point-of-Care Ultrasonography for Pediatric Ankle Fracture Detection
This prospective observational study evaluated the diagnostic accuracy of point-of-care ultrasonography (POCUS) for detecting ankle fractures in children presenting to the emergency department with acute isolated ankle trauma.
- Trial name
- NCT07872124
- Testing
- Point-of-Care Ultrasonography (POCUS)
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Obesity and Overweight
Exploring the Role of Baduanjin on Lumbar and Hip Mobility Index in Obese People Based on Infrared Thermography and Meridian Point Specificity
This study aimed to explore whether Baduanjin, a traditional fitness practice, can improve waist and hip mobility in obese individuals.
- Trial name
- NCT07035639
- Testing
- The Baduanjin intervention was designed following traditional Chinese health preservation principles and conducted under the guidance of certified instructors. The training sessions were led by nation
- Where
- China
- Volunteers
- 58 people
- Sponsor
- Chengdu Sport University
Fibromyalgia
Using the Chinese Indigenization FS Scale in the Diagnosis of Fibromyalgia： Specificity and Sensitivity in Clinical Practice
This study aimed to evaluate the specificity and sensitivity of the diagnostic criteria for fibromyalgia after conducting local validation in China.
- Trial name
- NCT06533410
- Testing
- The FM Diagnosis and Assessment Scale will be filled out, and there will be no other interventions beyond that
- Where
- China
- Volunteers
- 59 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Visual Learning, Healthy Volunteers
Generalization and Specificity of Visual Learning During Sleep
A growing body of evidence suggests that sleep facilitates and is beneficial to perceptual learning. However, the underlying mechanism of this facilitatory action is largely unknown.
- Trial name
- Visuallearning (NCT07015840)
- Testing
- Visual perceptual learning
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Brown University
Severe Sleep Apnea, Severe Insomnia
Mainstream Sleep Tracking Devices vs Polysomnography
The purpose of this study is to compare two popular portable sleep monitoring devices-the Fitbit Charge®, Jawbone UP®, and SleepTime smartphone app-to the "gold standard" Polysomnography (PSG).
- Conditions
- Severe Sleep Apnea, Severe Insomnia, Epileptiform Activity
- Trial name
- NCT02744235
- Testing
- Polysomnography Data, Jawbone UP®, Fitbit Charge ®
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- NYU Langone Health
Pheochromocytoma, Paraganglioma
Specificity of Elevated Plasma EM66 Levels in Pheochromocytoma
Pheochromocytoma or paraganglioma are tumors generating hypertension as a symptom. Different biological tests are currently available to diagnose these tumors.
- Conditions
- Pheochromocytoma, Paraganglioma, Essential Hypertension
- Trial name
- PHEO (NCT01022515)
- Testing
- plasma EM66 & CgA levels assessment, usual follow up with regular EM66 & Cga levels assessment
- Where
- 8 sites in France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Rouen
CAR T-Cell Therapy
An Evaluation Trial About Anti-claudin18.2 the Specificity of Chimeric Antigen Receptor T Cells in the Advanced Gastric / Esophagogastric Junction Adenocarcinoma and Pancreatic Cancer Subjects
An Evaluation Trial About Anti-claudin18.2 the Specificity of Chimeric Antigen Receptor T Cells in the Advanced Gastric / Esophagogastric Junction Adenocarcinoma and Pancreatic Cancer Subjects.
- Trial name
- NCT05277987
- Testing
- HEC-016(0.5×10^6 CAR-T Cells), HEC-016(0.5×10^6.5 CAR-T Cells), HEC-016(0.5×10^7 CAR-T Cells)
- Where
- China
- Volunteers
- 18 people
- Sponsor
- Shenzhen Fifth People's Hospital
HIV Infections, HIV Seronegativity
Studies of HIV-1 Infection in Newly Infected Individuals in Southern Africa
The main goal of this study is to find out how the immune system responds to a specific type of HIV infection, known as C HIV-1, in order to develop a vaccine against this type of infection.
- Trial name
- NCT00006298
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Alzheimer Disease, Mild Cognitive Impairment
Validation of the Montreal Cognitive Assessment in Patients With Mild and Major Neurocognitive Disorder
The primary aim of our study is to investigate the specificity, the sensitivity, and the overall diagnostic accuracy of the MoCA for mild and major NCD in a German-speaking population.
- Trial name
- MoCA-Valid (NCT03581643)
- Where
- Switzerland
- Volunteers
- 430 people
- Sponsor
- Andreas Monsch
Syphilis Infection
Evaluation of the Diagnostic Sensitivity and Specificity of the Determine™ Syphilis Advanced Test.
This is a prospective, multi-centre study which will evaluate the diagnostic sensitivity and specificity of the Determine™ Syphilis Advanced test.
- Trial name
- NCT06584214
- Testing
- Diagnostic test: Determine™ Syphilis Advanced test
- Where
- Uganda
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Abbott Rapid Dx
Pleural Effusion, Heart Failure
Comparing the Diagnostic Sensitivity and Specificity of Pleural Fluid N-Terminal Pro B-type Natriuretic Peptide (NT-proBNP) and Other Biochemical Gradient Criteria in Distinguishing Heart Failure and Non-heart Failure Related Pleural Effusions (CENTRE Study)
To assess the discriminative properties of pleural fluid (PF) N-terminal-proB-type-natriuretic-peptide (NTproBNP) levels in identifying heart failure (HF)-associated pleural effusions (PE).
- Conditions
- Pleural Effusion, Heart Failure, Malignant Neoplasm, Fluid Overload
- Trial name
- NCT05797649
- Where
- Hong Kong
- Volunteers
- 160 people
- Sponsor
- Chinese University of Hong Kong
Multiple Sclerosis
Motor Evoked Potentials With Modified Facilitation Technique
Investigating the change in Test- Retest- reliability in healthy individuals when applying a modified easy to use facilitation technique compared to standard facilitation technique and analyzing sensitivity and specificity in…
- Trial name
- EP-F (NCT03646929)
- Testing
- MEP using standard facilitation technique, MEP using modified facilitation technique
- Where
- Switzerland
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Chronic Disease, Goals
Effectiveness of a Personalized Health Profile on Specificity of Self-Management Goals
With a growing number of people living with chronic diseases, the need to empower people for self-management is rising. A key element in self-management is goal setting but the extent to which meaningful actionable goals (i.e.…
- Trial name
- NCT04175795
- Testing
- My Personal Brain Health Dashboard
- Where
- Canada
- Volunteers
- 420 people
- Sponsor
- McGill University
Acute Lymphoid Leukemia
Study of the Infusion of ARI-0001 Cells in Patients With CD19 + Acute Lymphoid Leukemia Resistant or Refractory to Therapy
To assess the efficacy (in terms of response rate and duration) of the infusion of ARI-0001 cells (Adult differentiated autologous T-cells from peripheral blood, expanded and transducted with a lentivirus to express a chimeric…
- Trial name
- CART19-BE-02 (NCT04778579)
- Testing
- ARI-0001 cells
- Where
- 9 sites in Spain
- Volunteers
- 50 people
- Sponsor
- Sara V. Latorre
Atherosclerosis
Study to Investigate the Sensitivity and Specificity of 3.0 Tesla MRI for Carotid Artery Plaque
The aim of this study is to develop non-invasive MRI, and MRS approaches that will quantify the plaque composition and lipid content of plaques and will have the potential for repeated in vivo measurements.
- Trial name
- NCT01632254
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)