Clinical trials: Specificity
Lateral Ankle Sprain
Mulligan Mobilization With Movement for Acute Lateral Ankle Sprains
This randomized controlled trial evaluates the effects and clinical specificity of Mulligan Mobilization With Movement (MWM) in adults with grade I or II lateral ankle sprains occurring less than 6 weeks before enrollment.
- Trial name
- NCT07849374
- Testing
- Mulligan Mobilization With Movement, Usual-Care Rehabilitation for Lateral Ankle Sprain
- Where
- Belgium
- Volunteers
- 110 people
- Sponsor
- Université Catholique de Louvain
Tuberculosis
A Trial of the C-Tb Skin Test, When Given Intradermally to Healthy Volunteers Previously Vaccinated With BCG
A new, more specific skin test to detect tuberculosis has been developed by Statens Serum Institut in Denmark. The new skin test is named C-Tb and like the current Tuberculin a positive test result will show as redness and/or…
- Trial name
- TESEC-03 (NCT01242475)
- Testing
- C-Tb, 2 TU Tuberculin PPD RT 23 SSI
- Where
- United Kingdom
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Statens Serum Institut
Asthma
Ability of Aridol to Detect Bronchial Hyperresponsiveness in Suspected Asthmatics
This is a Phase 3 study to determine the sensitivity and specificity of the Aridol bronchial challenge test to detect bronchial hyperresponsiveness in patients with suspected asthma.
- Trial name
- NCT00252291
- Testing
- Aridol, Methacholine, Exercise challenge
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Syntara
Seasonal Allergic Rhinitis, Healthy Subjects
A Pilot Monocenter Study to Assess Cellular and Soluble Biomarkers in Nasal Secretions
Allergic Rhinitis is an inflammatory disease which causes an influx of inflammatory cells and cytokines into the nasal mucosa. These biomarkers can also be found in the nasal secretions.
- Trial name
- NCT00297843
- Testing
- allergen challenge (grass pollen), nasal lavage
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fraunhofer-Institute of Toxicology and Experimental Medicine
Spinal Cord Injuries
Task-specificity for Locomotor Recovery Following SCI
The primary goal of the proposed study is to identify the contributions of the amount of task-specific practice on locomotor (i.e., walking) recovery in patients with chronic (> 1 yr) motor incomplete spinal cord injury (iSCI).
- Trial name
- NCT03144388
- Testing
- Variable Stepping Training, Variable Non-specific Training
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Indiana University
Down Syndrome, Edwards Syndrome
Expanded Noninvasive Genomic Medical Assessment: The Enigma Study
In January 2007, the American Congress of Obstetricians and Gynecologists (ACOG) revised its guidelines that now recommend physicians are ethically obligated to fully inform all pregnant women that screening for fetal chromosomal…
- Conditions
- Down Syndrome, Edwards Syndrome, Patau Syndrome, Klinefelter Syndrome
- Trial name
- NCT02787486
- Testing
- Blood sampling for Laboratory Developed Test (LDT) analysis
- Where
- 8 sites in United States
- Volunteers
- 760 people
- Sponsor
- Progenity, Inc.
Child, Only, Narration
Effects of a Group EMDR Intervention on Narrative Complexity and Specificity of Autobiographical Memories: the Hug the Child Study (HTC)
Background and study aims: The Eye Movement Desensitization and Reprocessing Group Protocol with Children (EMDR-GP/C) was first developed by Korkmazlar following the Marmara earthquake in Turkey in 1999 and can be adapted for…
- Conditions
- Child, Only, Narration, Memory Dysfunction, Distress, Emotional
- Trial name
- HTC (NCT05319002)
- Testing
- Group EMDR
- Where
- Italy
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Pisa
Allergy Skin Prick Test Reading
Digital Device Reading Skin Prick Test
Skin prick tests (SPTs), or intraepidermal tests, are the first diagnostic approach for people with a suspected allergy. SPTs are very simple, safe and quick.
- Trial name
- NCT06743737
- Testing
- Digital skin test reading device
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Healthy
In Vivo Specificity of KUC 7483 CL Co-administered With Bisoprolol, Propranolol, and Acipimox in Healthy Male Subjects
Study to compare the metabolic and electrolyte effects of a single oral dose of 320 mg ritobegron administered alone or with a pre- and comedication with bisoprolol, propranolol and acipimox.
- Trial name
- NCT02256722
- Testing
- KUC 7483 CL, Bisoprolol, Propranolol
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Peritonitis, Sepsis
The Value of PSP in Predicting Outcome in ICU Surgical Peritonitis Patients
The purpose of this study is to determine the diagnostic accuracy of Pancreatic Stone Protein (PSP) in predicting patient outcomes with suspected peritonitis in the Intensive Care Unit after abdominal surgery and compare PPS with…
- Conditions
- Peritonitis, Sepsis, Multiple Organ Failure, Death
- Trial name
- NCT01465711
- Testing
- All abdominal surgical procedures, Intubation, Imaging
- Where
- Germany
- Volunteers
- 137 people
- Sponsor
- University of Magdeburg
Major Depressive Disorder, Depressive Symptoms
A Randomised Controlled Clinical Trial of Memory Specificity Training (MEST) for Depression
Depression involves the tendency to recall overgeneral personal memories, a phenomenon which has been linked to numerous adverse psychological outcomes.
- Trial name
- MEST (NCT01882452)
- Testing
- Memory Specificity Training, Education and Support
- Where
- Australia
- Volunteers
- 60 people
- Sponsor
- Medical Research Council
Sub Acute Low Back Pain With Radiating Symptoms
Algo K Specific Manual Therapy for Sub Acute Low Back Pain With Radicular Symptoms
This study evaluates the effectiveness of a specific manual therapy approach based on the Algo-K decision algorithm in patients with subacute low back pain radiating to the lower limb.
- Trial name
- ALGO-K (NCT07118033)
- Testing
- Specific Manual Therapy, Non specific Manual Therapy
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Carcinoma, Renal Cell
Glycosaminoglycan Scores as Monitoring Biomarkers in Confined Renal Cell Carcinoma
In this study, a score based on glycosaminoglycan (GAG) profiling in subjects with suspicion of renal cell carcinoma (RCC) is hypothesized to distinguish malignant masses when early actionable clinical decisions are desirable.
- Trial name
- NCT02732652
- Where
- Sweden
- Volunteers
- 72 people
- Sponsor
- Chalmers University of Technology
Parkinson Disease, Cognition Disorder
The Impact TDCS-linked Motor and Cognitive Training Gains in Parkinson's Disease
This study is a group controlled clinical trial. Parallel study, patients aged 40-70 years, with Parkinson disease. Twelve sessions, three times a week, for 30 minutes, simultaneously to the rehabilitation program.
- Conditions
- Parkinson Disease, Cognition Disorder, Motor Disorders
- Trial name
- NCT04581590
- Testing
- Cognitive training
- Where
- Brazil
- Volunteers
- 242 people
- Sponsor
- Federal University of Paraíba
Heart Failure, Transplant; Failure, Heart
Cardiopulmonary Stress Testing (CPET) AlloSure Study
1. Cell-free DNA does not vary significantly as a function of the activity of immunologically quiescent cardiac transplant recipients, despite the metabolic demands of the transplanted organ.
- Trial name
- NCT04656080
- Testing
- CPET exercise testing
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Baylor Research Institute
Myositis, Polymyositis
Diagnostic Accuracy of Whole Body Magnetic Resonance Imaging in Inflammatory Myopathies
Idiopathic inflammatory myopathies (IIM) are a great concern in acquired muscle illnesses. An appropriate and rapid diagnosis is necessary, because morbidity and mortality are high and a specific treatment is needed.
- Conditions
- Myositis, Polymyositis, Dermatomyositis, Myositis, Inclusion Body
- Trial name
- DARWIM (NCT01432613)
- Testing
- MRI-oriented muscle biopsy
- Where
- France
- Volunteers
- 139 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pediatric Trauma Patients
Accuracy of Gastric POCUS in Pediatric Trauma
The goal of this observational study is to detect the predictive accuracy of the gastric POCUS in pediatric trauma patients undergoing urgent and semi urgent operative procedures.
- Trial name
- NCT06747403
- Volunteers
- 101 people
- Sponsor
- Assiut University
Periodontal Diseases, Periodontitis
Development, Validation, and Assessment of the Diagnostic Accuracy of a Questionnaire for Periodontitis Screening
The present study aims at validating the Italian version of one of the most widely used epidemiological questionnaires for periodontitis screening: the CDC/AAP questionnaire [hereafter referred to as the CDC/AAP_ITA…
- Trial name
- Q_ITA (NCT07461753)
- Volunteers
- 495 people, healthy volunteers welcome
- Sponsor
- Azienda Unità Sanitaria Locale (A.U.S.L.) Ferrara, Italy
Coronary Artery Disease
Single Blind Randomized Study to Determine the Sensitivity and Specificity of 2 Non-invasive Markers of Early Coronary Disease
Diagonal ear lobe crease and microcirculatory disorder in the conjunctiva are both non invasive methods documented in the literature as early signs of coronary artery disease.
- Trial name
- NCT01742156
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Gall Stones, Common Bile Duct
Fluorescent Cholangiography and Bile Duct Stones
Background. X-ray cholangiography has a high sensitivity and specificity of detecting bile duct stones and is the gold standard.
- Trial name
- NCT03530241
- Testing
- Presence of bile duct stones, Non-presence of bile duct stones
- Where
- Denmark
- Sponsor
- Hvidovre University Hospital