Clinical trials: Speckle Tracking Echocardiography
Heart Failure
Comparison of Three-dimensional and Two-dimensional Left Ventricle Strain With Speckle-tracking Echocardiography in Heart Failure With Reduced and Mildly Reduced Ejection Fraction
This study will compare two ultrasound techniques, 2D and 3D speckle-tracking echocardiography, for measuring how well the heart muscle contracts in patients with heart failure and reduced pumping function.
- Trial name
- 3V2-STEM-HF (NCT07741305)
- Where
- 5 sites in Italy
- Volunteers
- 419 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Left Ventricular Systolic Dysfunction
3D & Speckle Tracking Together as a Marker for Early Outcome in Cardiac Surgery
Patients presenting with Left Ventricle (LV) dysfunction undergoing cardiac surgery are at increased risk of perioperative morbidity and mortality.
- Trial name
- NCT02642770
- Testing
- Transesophageal echocardiography
- Where
- India
- Volunteers
- 73 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Hypertrophic Obstructive Cardiomyopathy
Speckle Tracking Echocardiography Analysis of Left Ventricular Myocardium After Percutaneous Intramyocardial Septal Radiofrequency Ablation for Hypertrophic Obstructive Cardiomyopathy
Objective to investigate the left ventricular (LV) systolic function by speckle tracking echocardiography before and after percutaneous intramyocardial septal radiofrequency ablation for hypertrophic obstructive cardiomyopathy…
- Trial name
- NCT04777188
- Testing
- Percutaneous Intramyocardial Septal Radiofrequency Ablation for hypertrophic obstructive cardiomyopathy
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Xijing Hospital
Ischemic Stroke, Cryptogenic, Ischemic Stroke, Embolic
Left Atrial Strain and Cryptogenic Stroke
Cryptogenic stroke is a type of stroke in which the cause of the blood clot cannot be identified, leaving many patients without a clear treatment plan and at high risk for another stroke.
- Conditions
- Ischemic Stroke, Cryptogenic, Ischemic Stroke, Embolic, Hemorrhagic Stroke, Embolic Stroke of Undetermined Source
- Trial name
- LAS-ESUS (NCT07224178)
- Where
- United States
- Volunteers
- 900 people
- Sponsor
- University of Pittsburgh
Mitral Regurgitation
Additive Prognostic Value of PALS Compared to Bernard's Staging in Patients Undergoing MV Surgery
Mitral valve prolapse is the most common cause of mitral regurgitation requiring surgery in developed countries. While cardiac surgery is recommended for symptomatic patients, in accordance with the ESC guidelines on valvular…
- Trial name
- PROSPECT-MIT (NCT07151495)
- Testing
- Speckle tracking and 2D echocardiography
- Volunteers
- 300 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Hypertension, Pulmonary Artery, Ventricular Dysfunction, Left
Characterization of LV Strain Patterns in Mildly Elevated PCWP and PAH.
The purpose of this study is to determine if patients with pulmonary hypertension and mildly elevated heart pressure known as PCWP will exhibit different patterns on echocardiography and that these patterns will predict treatment…
- Trial name
- LV strain (NCT01800292)
- Testing
- sildenafil
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Arizona
Myocardial Infarction
Two- Dimensional Speckle Tracking Echocardiography After Primary Percutaneous Coronary Intervention
ST-segment elevation myocardial infarction (STEMI) is a major cause of morbidity and mortality worldwide. In spite of decrease in acute and long-term mortality following STEMI in parallel with more use of reperfusion therapy…
- Trial name
- NCT04228510
- Testing
- 2D speckle tracking echocardiography
- Volunteers
- 204 people
- Sponsor
- Assiut University
Breast Cancer
Acute Exercise Cardioprotection From Doxorubicin
In rodents, a single bout of exercise prior to injection of a chemotherapy agent used to treat breast cancer prevents or attenuates a number of markers of cardiac injury.
- Trial name
- NCT02006979
- Testing
- exercise
- Where
- Canada
- Volunteers
- 27 people
- Sponsor
- University of British Columbia
Wilson's Disease, Myocardial Dysfunction
Subclinical Myocardial Dysfunction in Children With Wilson's Disease
Wilson's disease (WD) is one of the most common metabolic liver diseases in older children. The most frequent clinical presentation is liver disease. However, Wilson's disease (WD) is a multisystem disorder.
- Conditions
- Wilson's Disease, Myocardial Dysfunction, Children, Wilson Disease
- Trial name
- NCT07765472
- Testing
- Echocardiography, Electrocardiography, N-terminal pro b- type natriuretic peptide
- Where
- 2 sites in Egypt
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Hebatullah Fawzy
Echocardiography, Inflammatory Bowel Diseases
Value of Speckle Tracking Echocardiography Inflammatory Bowel Disease Patients
Value of speckle tracking echocardiography in early assessment of cardiac function in inflammatory bowel disease .
- Conditions
- Echocardiography, Inflammatory Bowel Diseases, Cardiac Function
- Trial name
- NCT06695065
- Volunteers
- 100 people
- Sponsor
- Assiut University
Surgical Procedure, Unspecified
Remimazolam and Propofol on the Left Ventricular Strain During Anesthesia Induction for Non-cardiac Surgery
This study to compare the impacts of remimazolam or propofol on the left ventricular global longitudinal strain (LV-GLS) during anesthesia induction for non-cardiac surgery.
- Trial name
- NCT05412914
- Testing
- Remimazolam infusion, Propofol infusion
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Konkuk University Medical Center
Coronary Artery Disease, Acute Myocardial Ischemia
Reduction of Ischemic Myocardium With Ranolazine-Treatment in Patients With Acute Myocardial Ischemia
The aim of the RIMINI-Trial is to examine the effect of Ranolazine on ischemic myocardium in acute myocardial ischemia. A pilot-trial by Venkatamaran et al.
- Trial name
- RIMINI-Pilot (NCT01797484)
- Testing
- Ranolazine
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Healthy, High Intensity Interval Training
Aerobic Interval and Moderate Continuous Exercise Training on Ventricular Functions
Hypoxic exposure increases right ventricular (RV) afterload by triggering pulmonary hypertension, with consequent effects on the structure and function of the RV.
- Conditions
- Healthy, High Intensity Interval Training, Exercise Training
- Trial name
- NCT04815460
- Testing
- High intensity-interval training (HIIT), Moderate intensity-continuous (MICT)
- Where
- Taiwan
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Portal Hypertension
Non-invasive Evaluation Program for TIPS and Follow Up Network
Evaluation of non-invasive prognostic parameters in patients receiving transjugular intrahepatic portosystemic shunt (TIPS) for complications of portal hypertension.
- Trial name
- NEPTUN (NCT03628807)
- Where
- Germany
- Volunteers
- 747 people
- Sponsor
- University Hospital, Bonn
Atrium; Fibrillation
Echocardiographic Left Atrial Function Assessment and Atrial Fibrillation Post-Coronary Artery Bypass Surgery
The aim of this study to investigate the correlation between preoperative LA function using 2D echocardiography and left atrium 2D speckle tracking strain echocardiography and the development of Post Operative AF after CABG.
- Trial name
- NCT03487419
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Heart Institute, Egypt
Echocardiography, 2-D
Specke Tracking Echocardiography And Filling Pressures
Determining the LV filling pressure is a key element in the diagnosis and management of patients with suspected decompensated heart failure.
- Trial name
- TEE (NCT02854865)
- Testing
- echocardiography
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Medical University of Vienna
Pacemaker DDD, His Bundle Pacing
Electrical and Mechanical Activation in PAcing The His Bundle Conduction sYstem
In recent years, the finding of long-term deleterious effects of right ventricular pacing (RVP) has led to an ongoing search for alternative pacing sites such as His bundle stimulation.
- Conditions
- Pacemaker DDD, His Bundle Pacing, Right Ventricular Pacing
- Trial name
- EMPATHY (NCT05222672)
- Testing
- His Bundle Pacing
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- University Hospital of Ferrara
Hypertension
Valsartan Versus Amlodipine Effect on Left Ventricular Multidirectional Deformation and Adipocytokines Level
Aim: To evaluate the effects of Valsartan versus Amlodipine on LV deformation in relation to plasma adiponectin and leptin levels in hypertensive individuals.
- Trial name
- NCT03990480
- Testing
- valsartan (160 mg/d), amlodipine (10 mg/d).
- Where
- Egypt
- Volunteers
- 230 people
- Sponsor
- Damanhour University
Heart Disease
Assessment of Cardiac Function and Anesthesia Depth in Patients Undergoing Cardiac Surgery
The SHAPE study is a prospective, randomized study evaluating changes in cardiac function in adult patients undergoing cardiac surgery with cardiopulmonary bypass.
- Trial name
- SHAPE (NCT07770269)
- Testing
- BIS-guided anesthesia: BIS 45-55, BIS-guided anesthesia: BIS 30-35
- Where
- Greece
- Volunteers
- 70 people
- Sponsor
- AHEPA University Hospital
Atrial Arrhythmia, Atrial Fibrillation (AF)
Study of AHRE Burden in Patients Undergoing Bachmann Bundle Area Pacing and Left Bundle Branch Pacing.
This prospective observational study evaluates the burden of Atrial High-Rate Episodes (AHRE) in patients without a prior history of atrial fibrillation who undergo concurrent Bachmann Bundle Area Pacing (BBAP) and Left Bundle…
- Conditions
- Atrial Arrhythmia, Atrial Fibrillation (AF), Pacemaker Implantation, Left Bundle Branch Pacing
- Trial name
- AHRE-BLAST (NCT07305194)
- Where
- Greece
- Volunteers
- 460 people
- Sponsor
- University Hospital of Patras