Clinical trials: Spectrum
Autism Spectrum Disorder, Caregiver Burden
Effectiveness of a Person-Centered Lifestyle Intervention in Mothers of Children With Autism Spectrum Disorder
Mothers of children with autism spectrum disorder (ASD) experience substantial physical, emotional, and social strain due to the demands of continuous caregiving.
- Conditions
- Autism Spectrum Disorder, Caregiver Burden, Quality of Life
- Trial name
- NCT07311252
- Testing
- Person-Centered Lifestyle Intervention
- Volunteers
- 30 people
- Sponsor
- Hacettepe University
Schizophrenia
Exploring the Effectiveness of Digital Anti-stigma Therapy on Illness Perception and Perceived Stigma in Patients With Schizophrenia and Their Primary Caregivers
This study aims to investigate the relationship between illness insight, self-stigma in patients with schizophrenia, and the awareness and associated stigma experienced by their families, as well as the predictors of these…
- Trial name
- NCT06563752
- Testing
- Participants will use 3D glasses to view VR educational information, routine care
- Where
- Taiwan
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Schizophrenia, Schizo Affective Disorder
Financial Incentives to Improve Medication Adherence
Medication adherence is a challenge in all of medicine and is associated with multiple negative outcomes. Strategies to better measure and enhance adherence to medication are urgent and necessary to minimize unwanted health…
- Conditions
- Schizophrenia, Schizo Affective Disorder, Bipolar Disorder, Depression
- Trial name
- NCT04191876
- Testing
- Wellth - Financial Incentives
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Northwell Health
Schizophrenia
Linagliptin and Mesenchymal Stem Cells: A Pilot Study
The purpose of the present study is to gather pilot data on the effects of linagliptin on the concentration of the long and short forms of SDF1-α (stromal cell-derived factor alpha) in humans, and to demonstrate the feasibility…
- Trial name
- NCT02442817
- Testing
- Linagliptin
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Nevada, Reno
SCHIZOPHRENIA 1 (Disorder), Schizo Affective Disorder
Non-invasive Brain Stimulation Using Tdcs of the Third (of Many) Visual Pathways
This study investigates the ability of transcranial direct current stimulation (tDCS) applied over the motion processing area of the brain (area MT) to improve face emotion recognition (FER) ability.
- Trial name
- ButtomVP (NCT07469384)
- Testing
- transcranial direct current stimulation
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Nathan Kline Institute for Psychiatric Research
Schizophrenia
Food Effect Study of Brexpiprazole Once-weekly (QW) Formulation in Patients With Schizophrenia
To investigate the effect of food on the pharmacokinetics of a single dose of brexpiprazole QW formulation.
- Trial name
- NCT06036108
- Testing
- OPC-34712FUM/ Brexpiprazole fumarate
- Where
- Japan
- Volunteers
- 59 people
- Sponsor
- Otsuka Pharmaceutical Co., Ltd.
Placenta Accreta Spectrum
Evaluation of Different Surgical Approaches Used for Conservative Management of Placenta Accreta Spectrum in Sohag University Hospital
The objective of this study is to evaluate different intra-operative procedures to control bleeding in cases of PAS disorders aiming to determine the best procedure regarding maternal morbidity and mortality post-operatively, and…
- Trial name
- NCT05510076
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Autism Spectrum Disorder, Obesity, Childhood
Family, Responsibility, Education, Support, and Health for Families With a Child With Autism
The objective of this proposed study is to collect initial efficacy data on a telehealth parent-based behavioral program for children with autism and overweight or obesity (PBT-A), compared with health education (HE).
- Conditions
- Autism Spectrum Disorder, Obesity, Childhood, Autism
- Trial name
- FRESH-A (NCT05741840)
- Testing
- PBT-A, Health Education (HE)
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Periprosthetic Joint Infection
Study to Evaluate the REMEDY SPECTRUM GV IM Spacer Nail in the Treatment of Ankle-Related Infections
This study is being conducted to evaluate the safety and effectiveness of the REMEDY SPECTRUM IM Spacer Nail in the treatment of ankle-related infections.
- Trial name
- NCT06428448
- Testing
- REMEDY Spectrum IM Spacer Nail
- Where
- 3 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- OsteoRemedies, LLC
Healthy Participants, Schizophrenia Diagnosis
Single and Multiple Ascending Doses of NTX-253 in Healthy Participants and Participants With Stable Schizophrenia
This study will assess the safety, tolerability, and pharmacokinetics of NTX-253 following oral administration in both healthy adult participants as well as adult participants with stable schizophrenia.
- Trial name
- NCT07344948
- Testing
- NTX-253
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Neurosterix
Schizophrenia
A Study to Analyze the Impact of Treatment With Paliperidone Palmitate on Clinical Outcomes and Hospital Resource Utilization in Adult Participants With Schizophrenia in Portugal
The purpose of this study is to investigate the mean number of schizophrenia-related hospital admissions, in adult participants with schizophrenia, occurred during 12 months before and 12 months after initiation of Paliperidone…
- Trial name
- PsiProsper (NCT03666715)
- Testing
- Oral Antipsychotics (OAPs), Paliperidone Palmitate 1-Month Formulation (PP1M)
- Where
- Portugal
- Volunteers
- 55 people
- Sponsor
- Janssen-Cilag Farmaceutica Ltda.
Autism Spectrum Disorder
An Exploratory Open Label Study of EPI-743 (Vincerinone TM) in Children With Autism Spectrum Disorder
The investigators hypothesize that EPI-743 may provide clinical benefit to children with Autism Spectrum Disorder.
- Trial name
- Autism (NCT02226458)
- Testing
- EPI-743
- Sponsor
- Edison Pharmaceuticals Inc
Coronary Disease, Myocardial Infarction
Chronical Illness-related Limitations of the Ability to Cope With Rising Temperatures, Third Wave
The CLIMATE-III Observational Study examines to what extent chronically ill patients experience adverse health effects because of heat and whether the patients' specific health behavior, somatosensory amplification, risk and…
- Conditions
- Coronary Disease, Myocardial Infarction, Heart Failure, Arrhythmias, Cardiac
- Trial name
- CLIMATE-III (NCT06890208)
- Testing
- No intervention
- Where
- Germany
- Volunteers
- 176 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Schizophrenia, Schizoaffective
Evaluation of QTc Interval by Continuous Holter ECG Recording in Antipsychotic Drug-treated Patients With Schizophrenia
The aim of this study is to evaluate the utility of continuous Holter ECG recording with automated, computerized data analysis for measuring antipsychotic-related QTc prolongation during a 24-h period under clinical conditions
- Conditions
- Schizophrenia, Schizoaffective, Bipolar Disorder
- Trial name
- NCT00178958
- Testing
- Holter Monitor
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Schizophrenia
Treating Refractory Schizophrenia With rTMS
Symptomatic treatment of the negative symptoms in schizophrenia (such as social withdrawal, affective flattening, poor motivation, and apathy) with medications and psychotherapy are almost non-existent, whereas treatment of the…
- Trial name
- NCT02242578
- Testing
- 1 Hz rTMS, 10 Hz rTMS
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Seton Healthcare Family
Autism Spectrum Disorder, Anxiety
Investigating a Marijuana-based Compound as a Treatment for Anxiety in Autistic Adults
The goal of this clinical trial is to learn if drug ABC works to treat severe asthma in adults. It will also learn about the safety of drug ABC.
- Trial name
- NCT06526208
- Testing
- MB-IMP
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Southwest Autism Research & Resource Center
Schizophrenia
Scale Validation Study for Prediction of Relapse and Short Term Rehospitalization in Patients With Schizophrenia
The purpose of this study is to establish and validate a scale/model that can be used to evaluate the duration of time and factors between short term hospital treatment and subsequent relapse periods in patients with…
- Trial name
- PRE-COG (NCT00358852)
- Testing
- No intervention
- Volunteers
- 2,339 people
- Sponsor
- Janssen-Cilag, S.A.
Autism, Autism Spectrum Disorder
Cognitive Training in Virtual Reality for Autism
The Virtual Reality Rehabilitation System (VRRS) is an innovative tool for motor and cognitive rehabilitation that has shown promising results in developmental populations, with evidence of feasibility, safety, acceptability, and…
- Trial name
- NCT07643649
- Testing
- Experimental Group, Control Group
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Schizophrenia Schizoaffective
Adjunctive Methylphenidate ER in Patients With Schizophrenia to Improve Functional and Cognitive Outcomes
Two of the major features of schizophrenia spectrum illness, negative and cognitive symptoms, have been associated with poor functional outcome and burden of illness.
- Trial name
- NCT05414058
- Testing
- Apo-Methylphenidate ER
- Where
- Canada
- Volunteers
- 35 people
- Sponsor
- The Royal Ottawa Mental Health Centre
Joubert Syndrome, Cerebello-oculo-renal Syndromes
Assessment of the Prevalence of Genes AHI1, NPHP1 and CEP290 in Joubert Syndrome
Primary objective: assessment of the prevalence of AHI1 mutations in Joubert syndrome and cerebello-oculo-renal syndromes (JS/CORS) Secondary objective: assessment of the prevalence of CEP290 mutations and NPHP1 homozygous…
- Trial name
- JSCORS (NCT00873678)
- Testing
- Whole blood sample
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris