Clinical trials: Speech
Aphasia, Stroke
Improvement of Language Disturbances After Stroke by Intensive Training and Electrical Brain Stimulation
The study aims to identify if intensive language training, consisting mainly of computer-based object naming, together with electrical brain stimulation, will lead to an improvement of language functions in patients that suffer…
- Trial name
- NCT00822068
- Testing
- anodal tDCS, cathodal tDCS
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University Hospital Muenster
Stroke, Aphasia
Choir Singing in Aphasia Rehabilitation
This study evaluates the verbal, cognitive, emotional, and neural efficacy of a choir singing intervention in chronic aphasic patients and their caregivers.
- Trial name
- NCT03501797
- Testing
- Singing-based rehabilitation, Standard care
- Where
- 2 sites in Finland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Traumatic Brain Injury, Hearing Loss
Improving Speech in Noise Using Noninvasive Stimulation
Traumatic brain injury, a common injury in military service personnel, often leads to poor processing of speech in noisy environments.
- Trial name
- NCT07176936
- Testing
- Cymba Conchae stimulation, Earlobe stimulation
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Florida
Aphasia
Effect of Dopaminergic Medication on Recovery of Aphasia
The investigators have been offering computer assisted therapy of aphasia (CAT) as a complement to traditional treatments to aphasia patients of the "Service of Neurorehabilitation" for some years.
- Trial name
- NCT00941265
- Testing
- levodopa and benserazide
- Where
- Switzerland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Central Auditory Disease, Healthy
Testing a Possible Cause of Reduced Ability of Children to Process Speech in Noise
This study aims to increase our understanding of the difficulty people have recognizing the spoken word, especially in noisy situations.
- Trial name
- NCT00001957
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Institute on Deafness and Other Communication Disorders (NIDCD)
Hearing Loss
Electrophysiological Study of Interindividual Differences in Speech-understanding Among Cochlear Implant Patients
Differences in speech-understanding and the quality of the subjective perception among cochlear implant patients (Digisonic SP) depends on numerous factors.
- Trial name
- NCT01805167
- Testing
- Electrophysiological study of the interindividual variability of vocal performance
- Where
- France
- Volunteers
- 17 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Aphasia, Stroke
The Effect of Non-invasive Brain Stimulation on Language Production in Post-stroke Aphasia
Aphasia is a language impairment caused by brain injury such as stroke that affects the ability to understand and express language, read and write due to damage in the language regions of the brain.
- Conditions
- Aphasia, Stroke, Language Disorders
- Trial name
- NCT04204356
- Testing
- Language treatment for improving discourse production, Transcranial direct-current stimulation (tDCS)
- Where
- United Kingdom
- Volunteers
- 6 people
- Sponsor
- King's College London
Speech, Autism Spectrum Disorder (ASD)
Research on Speech Development Trajectories and Predictive Models in Children With Autism Spectrum Disorder
Recent studies indicate that children with ASD have a significantly higher risk of co-occurring speech sound disorders than typically developing children.
- Trial name
- NCT07472829
- Testing
- Approaches to ASD social intervention
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Chongqing Medical University
Developmental Language Disorder, Language Delay
Using Neuroimaging and Behavioral Assessments to Understand Late Talking
Late talkers (LT), representing 10-20% of children under 3, demonstrate hallmark syntax and vocabulary deficits similar to preschoolers with developmental language disorder.
- Conditions
- Developmental Language Disorder, Language Delay, Language Development
- Trial name
- NCT06156865
- Testing
- Intervention to address late talking
- Where
- 2 sites in Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Corticobasal Syndrome, Progressive Supranuclear Palsy
Diagnosing Frontotemporal Lobar Degeneration
To establish diagnostic tools to make an accurate clinical and pathological diagnosis of patients with clinical FTLD syndromes
- Conditions
- Corticobasal Syndrome, Progressive Supranuclear Palsy, Behavioral Variant Frontotemporal Dementia, Semantic Dementia
- Trial name
- NCT02964637
- Testing
- Observational Study
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Electric Stimulation Therapy, Transcranial Magnetic Stimulation
Enhancing Speech Intelligibility Using Transcranial Alternating Current Stimulation (tACS)
This study contributes to fundamental research investigating the role of the articulatory-motor integration and cerebro-acoustic coherence in speech comprehension.
- Trial name
- StimSpeechCom (NCT04036630)
- Testing
- Transcranial alternating current stimulation (tACS), Transcranial magnetic stimulation (TMS) induced motor-evoked potentials (MEPs)
- Where
- Switzerland
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Logopenic Progressive Aphasia
Can Magnetic Brain Stimulation Improve Language Function in Primary Progressive Aphasia
The purpose of this study is to investigate the feasibility of using repetitive transcranial magnetic stimulation (rTMS) - a form of non-invasive brain stimulation - to improve language functioning in individuals who have the…
- Trial name
- NCT04193267
- Testing
- MagStim Rapid2 Transcranial Magnetic Simulation
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University of Manitoba
Stuttering, Childhood
Comparative Study Between Three Different Methods for Stuttering Therapy in Children
The aim of work is comparing between three different methods for treatment of stuttering in children in order to reach to the best method for treatment
- Trial name
- NCT05291572
- Testing
- speech therapy only, hyperbaric oxygen therapy, medical treatment
- Volunteers
- 30 people
- Sponsor
- Sohag University
Neurological Impairments, Genetic Syndrome
Speech Therapy and Parenting for Early Socio-communicAtive sKills
Every year, millions of children are diagnosed with neurodevelopmental disabilities. This term covers a wide range of conditions, from genetic syndromes to brain injuries such as cerebral palsy.
- Conditions
- Neurological Impairments, Genetic Syndrome, Neurodevelopmental Disability, Developmental Delays
- Trial name
- SPEAK (NCT06666777)
- Testing
- Intervention focused on intersubjective prelinguistic and socio-communicative skills, Standard speech therapy intervention
- Where
- 9 sites in Italy
- Volunteers
- 60 people
- Sponsor
- IRCCS Eugenio Medea
Brain Tumor
Use of Navigated Transcranial Magnetic Stimulation (nTMS) in Generated Motor and Language Mapping to Evaluate Brain Recovery Following Surgery
The goal of this clinical research study is to learn about using Navigated Transcranial Magnetic Stimulation (nTMS) in patients having surgery to remove a brain tumor in areas of the brain that control movement (motor function)…
- Trial name
- NCT02165995
- Testing
- Motor Mapping, Speech Mapping
- Sponsor
- M.D. Anderson Cancer Center
Nursing Home Residents
Feasibility of Risk Sign Displays to Prevent Falls, Dehydration and Pulmonary Aspiration in Nursing Homes
BACKGROUND: Prior research has shown a relationship between dehydration, falls and pulmonary aspiration among older adults in nursing and health care facilities, which contributes to its loss of independence and quality-of-life.
- Trial name
- NCT03123601
- Testing
- Risk sign displays
- Where
- Portugal
- Volunteers
- 20 people
- Sponsor
- Campus Neurológico Sénior
Neurodegenerative Diseases, Dementia
Neurofilament Light Chain And Voice Acoustic Analyses In Dementia Diagnosis
This cohort study aims to determine if a blood test can aid with diagnosing dementia in anyone presenting with cognitive complaints to a single healthcare network.
- Trial name
- NAVAIDD (NCT06339190)
- Testing
- Venepuncture
- Where
- 2 sites in Australia
- Volunteers
- 1,000 people
- Sponsor
- Monash University
Oral Mucositis, Quality of Life
Effect of a Novel Topical Composition on the Incidence of Severe Oral Mucositis in Head & Neck Cancer Radiated Patients and Quality of Life Assessed by PROMs.
The use of a novel topical mucosa composition (XCM-OM118) comprising 2-(trimethylazaniumyl) acetate; (2R,3R,4S)-pentane-1,2,3,4,5-pentol; Hexadecanoic acid; (9Z, 12Z)-octadeca-9,12-dienoic acid; octadecanoic acid…
- Conditions
- Oral Mucositis, Quality of Life, Mucositis, Pain
- Trial name
- STOPOMP (NCT05635929)
- Testing
- XCM-OM118 Composition comprising olive oil, betaine and xylitol
- Where
- Spain
- Volunteers
- 63 people
- Sponsor
- Mucosa Innovations, S.L.
Primary Progressive Aphasia, Caregiver Burnout
PPA Tele-Savvy: A Pilot Study of an Online Intervention for Caregivers of Persons Living With PPA
The primary goal of this pilot project is to adapt an evidence-informed on-line psychoeducation program (Tele-Savvy) to address the unique challenges facing informal caregivers of those living with PPA and geared toward achieving…
- Trial name
- NCT04412083
- Testing
- PPA Tele-Savvy Pilot Intervention
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Northwestern University
Speech
Speech Motor Learning and Retention (Aim 1)
The overall goal of this research is to test a new model of speech motor learning, whose central hypothesis is that learning and retention are associated with plasticity not only in motor areas of the brain but in auditory and…
- Trial name
- NCT06467305
- Testing
- continuous theta-burst stimulation (cTBS), Adaptation
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Yale University