Clinical trials: Speech and Language Therapy
Aphasia, Stroke
Post-Stroke Aphasia and Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment Study
In this study the investigators will examine the efficacy of navigated excitatory repetitive transcranial magnetic stimulation (nerTMS) for the treatment of post stroke aphasia.
- Trial name
- PART (NCT01512264)
- Testing
- Magstim SuperRapid
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Alabama at Birmingham
Aphasia
NOn-invasive Repeated THerapeutic STimulation for Aphasia Recovery
The current standard of care for rehabilitation of patients with aphasia after stroke is conventional speech and language therapy (SLT).
- Trial name
- NORTHSTAR (NCT02020421)
- Testing
- rTMS, tDCS
- Where
- 6 sites in United States, Canada and 1 more
- Volunteers
- 63 people
- Sponsor
- Dr. Alexander Thiel
Aphasia, Primary Progressive, Repetitive Transcranical Magnetic Stimulation
rTMS for the Treatment of Primary Progressive Aphasia: A Randomized Controlled Trial
The primary progressive aphasia (PPA) is a neurodegenerative condition characterized by a gradual, irreversible decline of language function (Mesulam, 2001). There are no known treatments for PPA so far.
- Trial name
- NCT03448133
- Testing
- Magstim rTMS
- Volunteers
- healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Aphasia, Language Disorders
Evaluation of the Effects of Response Elaboration Training for Aphasia
The purpose of this study is to evaluate the effects of Response Elaboration Training (RET), which is a speech/language therapy for aphasia.
- Conditions
- Aphasia, Language Disorders, Speech Disorders
- Trial name
- NCT00125216
- Testing
- Response Elaboration Training
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Stroke, Aphasia
Impact of Neuromodulation on Language Impairments in Stroke Patients
Up to 40% of stroke survivors suffer from aphasia, making recovery of language abilities a top priority in stroke rehabilitation. Conventional speech and language therapy may have limited effectiveness.
- Trial name
- NCT03699930
- Testing
- tDCS, Speech and language therapy
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Casa Colina Hospital and Centers for Healthcare
Simulation Training
Effectiveness of Two Simulation-Based Functional Nasopharyngoscopic Velopharyngeal Assessment Trainings
The aim of this clinical trial was to compare the effectiveness of functional nasopharyngoscopic velopharyngeal assessment training given to undergraduate speech and language therapy students on a 3D printed endoscopy training…
- Trial name
- NCT05732376
- Testing
- Nasopharyngoscopic Velopharyngeal Training with 3D Printed Endoscopy Training Model, Nasopharyngoscopic Velopharyngeal Training with Ready-Made Endoscopy Training Model
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Medipol University
Speech Disorders, Voice Disorders
The Effect of Combined Speech and Music-therapy on the Speech Characteristics of People With Parkinson's Disease (PD)
Speech and voice disorders are observed in almost 90% of patients with PD during their course of illness. Reduced voice pitch inflections or monotone speech, reduced vocal loudness, prosody disorders, the imprecise articulation…
- Conditions
- Speech Disorders, Voice Disorders, Parkinson Disease
- Trial name
- NCT04966689
- Testing
- combined speech and music therapy, speech therapy, music therapy
- Where
- Iran
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Iran University of Medical Sciences
Stroke, Aphasia
Study of the Participation of People With Aphasia Post Stroke and Their Caregivers in Valladolid Region (Spain)
The objective of this study is to determine the level of community participation of people with post-stroke aphasia and their caregivers, as well as the factors that facilitate or interfere with this participation in the…
- Trial name
- SPART-A (NCT06948721)
- Volunteers
- 50 people
- Sponsor
- Centro Integral de Rehabilitación
Neurological Impairments, Genetic Syndrome
Speech Therapy and Parenting for Early Socio-communicAtive sKills
Every year, millions of children are diagnosed with neurodevelopmental disabilities. This term covers a wide range of conditions, from genetic syndromes to brain injuries such as cerebral palsy.
- Conditions
- Neurological Impairments, Genetic Syndrome, Neurodevelopmental Disability, Developmental Delays
- Trial name
- SPEAK (NCT06666777)
- Testing
- Intervention focused on intersubjective prelinguistic and socio-communicative skills, Standard speech therapy intervention
- Where
- 9 sites in Italy
- Volunteers
- 60 people
- Sponsor
- IRCCS Eugenio Medea
Stroke, Aphasia
Comparison of Therapeutic Effect Between Speech Rehabilitation Program and Speech Therapy in Stroke Patients With Aphasia
Our study will provide precise and intensive speech rehabilitation treatment program to patients with speech disorders after stroke, and compare clinical evaluations with the conventional speech therapy patient group.
- Conditions
- Stroke, Aphasia, Speech Therapy
- Trial name
- NCT06361901
- Testing
- Zenicog;language rehabilitation program, Conventional language rehabilitation
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Korea University Guro Hospital
Language Development Disorders, Speech Sound Disorder
Manipulating Linguistic Complexity to Improve Child Language Treatment Outcomes
Phonological disorder (PD) and specific language impairment (SLI) directly impact a child's ability to communicate and are among the most prevalent developmental disorders.
- Trial name
- NCT03977701
- Testing
- Phonological treatment, Morpheme treatment
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- San Diego State University
Stroke, Aphasia
pBFS-guided cTBS at Different Doses for Aphasia After Stroke
The objective of this trial is to evaluate the effectiveness and safeness of different doses of continuous Theta Burst Stimulation (cTBS) over the right Superior Frontal Gyrus (SFG), guided by personalized Brain Function Sector…
- Trial name
- NCT05969548
- Testing
- active 1200-pulse continuous Theta Burst Stimulation, active 2400-pulse continuous Theta Burst Stimulation, active 3600-pulse continuous Theta Burst Stimulation
- Where
- 2 sites in China
- Volunteers
- 60 people
- Sponsor
- Changping Laboratory
Dysarthria, Acquired Brain Injury
ACURES: Acoustic and Respiratory Parameters for Dysarthria Assessment
The goal of this observational study is to describe speech and breathing patterns in adults after acquired brain injury (ABI) and understand how these patterns relate to the presence, severity, and type of dysarthria.
- Trial name
- ACURES (NCT07435155)
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- University of Salamanca
Aphasia
Semantic Feature Analysis Treatment for Aphasia
This randomized controlled comparative effectiveness study examines manipulation of a key component of an established and efficacious treatment for naming impairments in aphasia, along with cognitive and brain correlates of…
- Trial name
- NCT04215952
- Testing
- Semantic Feature Analysis Treatment
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- VA Pittsburgh Healthcare System
Cerebral Palsy Children, Children With Traumatic Brain Injury
Cerebrolysin Neural Repair Therapy in Children With Traumatic Brain Injury and Cerebral Palsy
Cerebral palsy (CP) is the most frequent cause of motor handicap among children. The economic burden of CP in USA includes $1.18 billion in direct medical costs, $1.05 billion in direct non-medical costs, and an additional $9.24…
- Conditions
- Cerebral Palsy Children, Children With Traumatic Brain Injury, Mental Handicap, Delayed Speech Development
- Trial name
- NCT02116348
- Testing
- Cerebrolysin (Nerve growth factor)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Ischaemic Stroke, Hemorrhagic Stroke
Exploratory Study on the Potential Cross-System Effects of BCI-FES Hand Therapy on Dysphagia and Aphasia in Chronic Stroke Patients
The goal of this neurorehabilitation explorative study is to investigate how a closed-loop Brain-Computer Interface Functional Electrical Stimulation (BCI-FES) therapy, used within the intended purpose for hand rehabilitation…
- Trial name
- c-STEPS (NCT06940635)
- Testing
- closed-loop BCI-FES device
- Where
- Austria
- Volunteers
- 10 people
- Sponsor
- VASCage GmbH
Aphasia, Stroke
Clinical Feasibility of Transcranial Direct Current Stimulation [tDCS] With Standard Aphasia Therapy
Study Design: This is a within-subjects crossover design. Subjects will participate in the procedures twice, once under each condition (active vs. sham stimulation).
- Trial name
- NCT03272906
- Testing
- Anodal transcranial direct current stimulation, Speech-language therapy
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Louisiana State University and A&M College
Swallowing Disorders, Dysphagia
Development and Validation of the SWADOC Tool
Background: After a period of coma, patients with severe brain injury may present disorders of consciousness (DOC). A wide proportion of these patients also suffer from severe dysphagia.
- Conditions
- Swallowing Disorders, Dysphagia, Disorders of Consciousness, Assessment Tool
- Trial name
- NCT04706689
- Testing
- SWADOC tool, FOTT-SAS
- Where
- 8 sites in Belgium, France
- Volunteers
- 104 people
- Sponsor
- University of Liege
Cough, Speech Therapy
Speech Therapy in the Management of Chronic Cough
Speech and language intervention (speech therapy) is one of the few methods which seem to be useful in management of persistent chronic cough.
- Trial name
- NCT03457610
- Testing
- Speech and language intervention
- Where
- Poland
- Volunteers
- 30 people
- Sponsor
- Medical University of Warsaw
Anomia, Aphasia
Cognitive Therapy to Improve Word Finding
Adults who sustain brain damage due to stroke, traumatic injury or surgery may develop difficulty finding words. This study compares the effectiveness of two behavior-based programs to improve picture naming ability in these…
- Conditions
- Anomia, Aphasia, Traumatic Brain Injury, Cerebrovascular Accident
- Trial name
- NCT00494520
- Testing
- Errorful training condition, Errorless training condition
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Georgetown University