Clinical trials: Sperm
Infertility, Male
Effect of Ejaculatory Abstinence on Semen Parameters in Male Factor Infertility Patients
The purpose of this study is to compare semen parameters with in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) when male factor infertility patients abstain from ejaculation more than 48 hours (routine care)…
- Trial name
- NCT04206800
- Testing
- Ejaculatory abstinence less than 24 hours
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Boston IVF
Male Infertility
Tobacco and Sperm Genome: Effects of Smoking Cessation
Tobacco is a male infertility risk factor. Many studies comparing smokers to non-smokers have shown effects on spermatogenesis and the quality of the male gamete.
- Trial name
- TABAGERM (NCT03552081)
- Testing
- Fragmented DNA evaluation in blood and semen samples
- Where
- France
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Fertilization Failure
Calcium Ionophore Solution Can Increase Fertilization Rate in Patients During Intracytoplasmic Sperm Injection(ICSI) Who Have Poor Ovarian Reserve?
The aim of this study is to evaluate calcium ionophore solution on fertilization rate of patients during intracytoplasmic sperm injection who have poor ovarian reserve
- Trial name
- NCT02045914
- Testing
- calcium ionophore solution
- Where
- Turkey (Türkiye)
- Volunteers
- 162 people
- Sponsor
- Baskent University
Semen Analysis, ICSI
Evaluating the Utility of Implementing Microfluids for Sperm Preparation Compared to Conventional Method of Density Gradient Centrifugation in a PGT-A Program: a Sibling Oocyte Study
In assisted reproductive technology (ART), sperm preparation aims to select the most viable sperm for ICSI. Unlike conventional methods like density gradients or sperm washing, microfluidic techniques mimic natural selection in…
- Conditions
- Semen Analysis, ICSI, PGT-A
- Trial name
- NCT07093619
- Testing
- FERTILE Plus
- Where
- United Arab Emirates
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Controlled Ovarian Stimulation
Study to Assess the Design of Use of REKOVELLE® in Women Undergoing In Vitro Fertilisation or Intracytoplasmic Sperm Injection Procedures in Routine Clinical Practice
The aim of the study is to explore how the individualized dosing regimen of REKOVELLE is used in routine clinical practice and to describe the effectiveness and safety of REKOVELLE under real-world conditions.
- Trial name
- DELTA (NCT04503707)
- Testing
- Follitropin Delta
- Where
- 14 sites in France
- Volunteers
- 250 people
- Sponsor
- Ferring Pharmaceuticals
Healthy Volunteers, Normocholesterolaemic Men
Effects of Atorvastatin on Human Semen and Gonadal Hormones
Recently, concerns about the effect of atorvastatin intake on men fertility have been raised. However, this statin has never been investigated regarding its influence on male fertility, notably sperm quality.
- Conditions
- Healthy Volunteers, Normocholesterolaemic Men, Normozoospermic Men
- Trial name
- NCT02094313
- Testing
- Atorvastatin
- Where
- France
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Asthenozoospermia
Effect of Pentoxifylline + CoQ10 vs CoQ10 Alone on Sperm Motility in Subfertile Men With Asthenozoospermia
The goal of this clinical trial is to learn if drug Pentoxifylline plus Coenzyme Q10 work to treat asthenozoospermia in subfertile male. It will also learn about the safety of drug Pentoxifylline plus Coenzyme Q10.
- Trial name
- NCT07252518
- Testing
- Coenzyme Q 10, Pentoxifylline 400 MG Oral Tablet
- Where
- Bangladesh
- Volunteers
- 56 people
- Sponsor
- Mst.Sumyara Khatun
Infertility, IVF
PICSI RCT in Couples With a Previous Poor Fertilisation Cycle in IVF
Poor fertilisation plays a significant role in poor artificial reproductive technique outcomes. Male factor infertility accounts for a large portion of such cases.
- Trial name
- NCT05017740
- Testing
- ICSI, PICSI
- Where
- Singapore
- Volunteers
- 47 people
- Sponsor
- KK Women's and Children's Hospital