Clinical trials: Sperm DNA Fragmentation
Infertility Unexplained, Infertility, Male
Impact of DNA Fragmentation in Sperm on Pregnancy Outcome After Intra-uterine Insemination in a Spontaneous Cycle
Infertility affects about 10% of all couples and is defined by a failure to achieve a clinical pregnancy within a year of regular unprotected sexual intercourse.
- Conditions
- Infertility Unexplained, Infertility, Male, DNA Damage
- Trial name
- NCT03319654
- Testing
- DNA fragmentation by TUNEL assay
- Where
- Belgium
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Sperm DNA Fragmentation, Embryo Quality
Sperm Selection by Microfluidic Separation Improves Embryo Quality
This is a randomized controlled trial of couples with a history of poor embryo quality undergoing a repeat in vitro fertilization (IVF) cycle for unexplained infertility.
- Conditions
- Sperm DNA Fragmentation, Embryo Quality, Fertility Disorders, Infertility
- Trial name
- SPERM (NCT03085433)
- Testing
- Microfluidic Sperm Sorting, in vitro fertilization
- Where
- United States
- Volunteers
- 393 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Sperm DNA Fragmentation, Infertility, Male
Impact of Escitalopram on Sperm DNA Fragmentation
Double-blind placebo-controlled randomized trial of daily escitalopram for 6 weeks in healthy men with normal semen analyses and no psychiatric history of depression, bipolar, mania or suicidal ideation.
- Trial name
- NCT03527043
- Testing
- Escitalopram
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University