Clinical trials: Spinal Anesthesia Hypotension
Cesarean Section
Development of a Risk Prediction Model for Post-Spinal Anesthesia Hypotension During Cesarean Delivery Using Heart Rate, Blood Pressure, Perfusion Index, ECG Waveforms, and SpO₂ Waveforms
Spinal anesthesia is the preferred anesthetic technique for patients undergoing cesarean section. Compared with general anesthesia, spinal anesthesia offers multiple advantages.
- Trial name
- NCT07689825
- Testing
- Standard clinical spinal anesthesia and routine intraoperative monitoring
- Where
- China
- Volunteers
- 145 people
- Sponsor
- Peking University Shenzhen Hospital
Hypotension
Echocardiography Based Algorithm for Spinal Anaesthesia
The main aim of the study is to compare the proposed algorithm for preventing and treating spinal hypotension with normal anesthesia management of a spinal anesthesia.
- Trial name
- NCT03106649
- Testing
- Echocardiography, Treatment of spinal hypotension
- Where
- India
- Volunteers
- 60 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Healthy Participants
Rate of Tranexamic Acid Administration on Blood Pressure (RateTXA) Study.
Tranexamic acid is a well-established treatment for post-partum hemorrhage. This study aims to examine the effect of tranexamic acid administration rates on blood pressure changes over 1 minute compared to 10 minutes in healthy…
- Trial name
- RateTXA (NCT06356948)
- Testing
- Tranexamic Acid (TXA)
- Where
- Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Hypotension After Spinal Anesthesia
Preoperative Oral Heptaminol Hydrochloride in Preventing Hypotension After Spinal Anesthesia
Methodologies and approaches have been implemented with differing degrees of success to prevent neuraxial hypotension. Currently utilized approaches to prevent hypotension during spinal anesthetic administration consist of…
- Trial name
- NCT06564935
- Testing
- Heptaminol Hydrochloride
- Volunteers
- 160 people
- Sponsor
- Cairo University
Spinal Anesthesia-induced Hypotension
Predicting if the Blood Pressure Will Drop After Spinal Anesthesia Using Ultrasound of the Neck
After a spinal injection, blood pressure might drop for a short time, similar to what happens with general anesthesia. This drop can be different for each person.
- Trial name
- NCT06711289
- Testing
- Carotid ultrasound measurement, Vital sign measurement, Spinal anesthesia
- Where
- Netherlands
- Volunteers
- 44 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Hypotension After Spinal Anesthesia, Hypotension During Cesarean Delivery
Comparison of the Efficacy of Continuous Metaraminol Infusion Versus Continuous Norepinephrine Infusion for the Prevention of Hypotension During Cesarean Section Under Spinal Anaesthesia. A Randomised Controlled Trial.
The aim of this double-blind randomised study will be to compare a fixed-rate prophylactic metaraminol infusion to a fixed-rate prophylactic norepinephrine infusion during elective cesarean section under combined spinal-epidural…
- Trial name
- NCT07363109
- Testing
- Metaraminol infusion, Norepinephrine infusion
- Volunteers
- 80 people
- Sponsor
- Aretaieion University Hospital
Intraoperative Hypotension, Spinal Aneshtesia
Dural Sac Area-Guided Spinal Anesthesia Dosing for TURP
This randomized controlled study will evaluate whether individualizing the dose of spinal anesthesia according to the ultrasound-derived dural sac cross-sectional area (DSCSA) can improve hemodynamic stability in patients…
- Conditions
- Intraoperative Hypotension, Spinal Aneshtesia, TURP(Transurethral Resection of Prostate)
- Trial name
- NCT07794852
- Testing
- DSCSA-Guided Individualized Spinal Anesthesia Dosing, Bupivacaine, Fentanyl (FEN)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University
Cesarean Section Complications, Spinal Anesthetic Toxicity
Comparison of Vasopressor Boluses for Management of Hypotension After Spinal Anesthesia
In this study the investigators will compare the efficacy and side effects of two doses of norepinephrine bolus (6 mcg and 10 mcg) in management of maternal hypotensive episode after subarachnoid block during Cesarean delivery.
- Trial name
- NCT03712111
- Testing
- Norepinephrine 6 mcg, Norepinephrine 10 mcg, Bupivacaine Hydrochloride
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Cairo University
Post-spinal Anesthesia Hypotension
Ultrasonographic Evaluation of Internal Jugular Vein Cross Sectional Area for Prediction of Post Spinal Hypotension
The aim of this study is to evaluate the efficacy of internal jugular cross sectional area for predicting the occurrence of PSAH.
- Trial name
- NCT04780139
- Testing
- Ultrasonographic Evaluation of Internal Jugular Vein Cross Sectional Area
- Where
- Egypt
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Cesarean, Spinal Anesthesia
Prediction of Maternal Arterial Hypotension After Spinal Anesthesia by Passive Leg Raise Test.
Spinal anesthesia for cesarean section is associated with a high incidence of low blood pressure. However, the pathophysiology of this arterial hypotension is not unequivocal and could involve, in addition to drug vasoplegia, a…
- Trial name
- EDLIDL (NCT05133271)
- Testing
- Clinical hemodynamic and echocardiographic evaluation
- Where
- France
- Volunteers
- 64 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Caesarean Delivery, Hypotension Postprocedural
Comparison of Classic and Sequential Spinal Techniques for Preventing Hypotension During Cesarean Delivery.
Given the clinical importance of maternal hypotension, the potential advantages of sequential spinal dosing warrant formal evaluation in a prospective, adequately powered randomized controlled trial.
- Trial name
- NCT07327866
- Testing
- Classic group, Sequential group
- Where
- Egypt
- Volunteers
- 94 people
- Sponsor
- Al-Azhar University
Remimazolam, Spinal Anesthesia
The Effect of Remimazolam and Dexmedetomidine on the Incidence of Hypotension During Spinal Anesthesia
The goal of this clinical trial is to compare the effect of remimazolam and dexmedetomidine on the incidence of hypotension during spinal anesthesia in adult patients.
- Trial name
- NCT05935657
- Testing
- Remimazolam, Dexmedetomidine
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Pusan National University Yangsan Hospital
Spinal Aneshtesia, Hypotension After Spinal Anesthesia
Comparing Two Different Norepinephrine Infusion Rates for Prophylaxis Against Spinal-induced Hypotension in Elderly
The current study aims to determine whether norepinephrine infusion rate (0.07 mcg/kg/min) is non-inferior to the higher dose (0.1 mcg/kg/min) in maintaining intraoperative blood pressure maintaining blood pressure of elderly…
- Conditions
- Spinal Aneshtesia, Hypotension After Spinal Anesthesia, Elderly (People Aged 65 or More)
- Trial name
- NCT07077265
- Testing
- Norepinephrine (0.1 μg/kg/min), Norepinephrine (0.07 μg/kg/min)
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Kasr El Aini Hospital
Hypotension
Effect of Position During Spinal Anesthesia on Hemodynamic Change in Cesarean Section
Hypotension is the most common complications after spinal anesthesia especially in pregnant patients who undergoing cesarean section. Position during spinal anesthesia may be altering the hemodynamic.
- Trial name
- NCT02253381
- Testing
- Right, Left
- Where
- Thailand
- Volunteers
- 140 people
- Sponsor
- Prince of Songkla University
Planned Cesarean Section
Acute Preoperative Stress and Hypotension After Spinal Anesthesia. SAS for "Salivary Amylase and Stress "
Spinal anesthesia is the technique of choice for planned cesarean section. It is associated with a high frequency of maternal hypotension.
- Trial name
- SAS (NCT01862055)
- Where
- France
- Volunteers
- 79 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hypotension, Cesarean Section
Comparison of Hypotension During Spinal Anaesthesia for C-section
Maternal hypotension during C section has been reported due to aortocaval compression (ACC) by full term uterus in supine position. This study aimed at reporting the effect of left tilt on maternal hemodynamics.
- Conditions
- Hypotension, Cesarean Section, Aortocaval Compression
- Trial name
- NCT05427968
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Rawalpindi Medical College
Hypotension Drug-Induced, Spinal Aneshtesia
Effect of Lateral Decubitus Position After Spinal Anesthesia on Hemodynamic Stability in High-Risk Geriatric Patients
Spinal anesthesia is a common and preferred anesthetic technique for lower extremity orthopedic surgery in elderly patients. However, it can cause a significant drop in blood pressure (hypotension), especially in high-risk older…
- Conditions
- Hypotension Drug-Induced, Spinal Aneshtesia, Geriatric, Orthopedic Surgery Patients
- Trial name
- NCT07597148
- Testing
- Lateral Decubitus Positioning, Immediate Supine Positioning
- Volunteers
- 70 people
- Sponsor
- University of Health Sciences Balikesir Hospital Eduation and Research
Anesthesia
Effect of Acupoint Electrical Stimulation on Incidence of Hypotension After Spinal Anesthesia
This study is intended to include elderly patients who are selected to undergo lower limb and pelvic orthopedic surgery under spinal anesthesia.
- Trial name
- NCT05716399
- Testing
- Transcutaneous electric stimulation pretreatment, Transcutaneous acupoint electrical stimulation treatment, Transcutaneous acupoint pseudo electric stimulation
- Volunteers
- 111 people
- Sponsor
- Shanghai Tongji Hospital, Tongji University School of Medicine
Adverse Effect
Intensive Versus Standard Treatment for Hypotension on Maternal Hemodynamics in Preeclamptic Patients
The objective of this study is to investigate the impact of varying maternal blood pressure maintenance targets on maternal hemodynamics in preeclamptic patients following cesarean section.
- Trial name
- NCT06151444
- Testing
- Alpha-Agonist, α-adrenergic receptor agonist
- Volunteers
- 160 people
- Sponsor
- General Hospital of Ningxia Medical University
Hypotension
Investigating Maternal Effects of Positions Applied in Patients Preparing for Caesarean Section Under Spinal Anesthesia
After the approval of the Ethics Committee, 120 patients were planned to be included in the study between 15.06.2022 and 15.01.2023.
- Trial name
- cs position (NCT05595928)
- Testing
- position
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people
- Sponsor
- Aydin Maternity and Child Health Hospital