Clinical trials: Spinal Anesthesia for Cesarean Section
Hypotension
Colloid Preload Versus Crystalloid Co-load in Cesarean Section Under Spinal Anesthesia
Comparison between colloid preload and crystalloid co-load in cesarean section under spinal anesthesia. 1. The primary outcome was the incidence of hypotension 2.
- Trial name
- CPvsCC (NCT03107598)
- Testing
- colloid preload
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- University Hospital, Mahdia
Healthy, Pain
Intrathecal Hydromorphone for Post-cesarean Delivery Pain - a Dose Finding Study
Pain relief after cesarean delivery can be provided in a few ways. Most commonly, certain medications called opioids, such as morphine, are given through the vein or into the muscle.
- Conditions
- Healthy, Pain, Pregnancy
- Trial name
- NCT01943565
- Testing
- Hydromorphone 25mcg, Hydromorphone 50mcg, Hydromorphone 100mcg
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Epidural and Spinal Anesthesia for Cesarean Delivery
How Sweet is it? Measurement of Glucose in Epidural and Spinal Fluid
When a woman requires a cesarean section after labour, anesthesia is usually provided by a pre-existing epidural. Occasionally, the epidural does not work. The anesthesiologist then may give a "spinal anesthetic".
- Trial name
- NCT01391702
- Where
- 2 sites in Canada
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Dexamethasone, Magnesium Sulphate
Dexamethasone Versus Magnesium Sulphate as an Adjuvant to Bupivacaine in Ultrasound Guided Erector Spinae Plane Block for Postoperative Analgesia in Elective Caesarean Section Under Spinal Anesthesia
This study aims to compare the efficacy of adding dexamethasone and magnesium sulfate as an adjuvant to bupivacaine in bilateral erector spinae block in postoperative pain control in patients undergoing caesarean section under…
- Conditions
- Dexamethasone, Magnesium Sulphate, Adjuvant, Ultrasound
- Trial name
- NCT07139522
- Testing
- Bupivacaine, Dexamethasone, Magnesium sulphate
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Cairo University
Cesarean Section, Spinal Anesthesia
Evaluation of Mitochondrial Enzyme Activity in Cesarean Section Patients
The goal of this observational study is to learn about in effects of trace element metabolism, tricarboxylic acid cycle enzyme activities and thiol/disulfide balance in patients who underwent cesarean section under spinal…
- Conditions
- Cesarean Section, Spinal Anesthesia, Thiol Groups
- Trial name
- NCT06206928
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital
Granisetron
Role of Granisetron in Preventing Hypotension After Spinal Anesthesia With Levobupivacaine in Rheumatic Patients Undergoing Elective Cesarean Section
Cardiac disease in pregnancy is a high-risk condition and a major cause of maternal mortality and morbidity. Although direct or immediate death due to cardiovascular disease is rare, it is an important indirect cause of maternal…
- Trial name
- NCT05314257
- Testing
- Granisetron Hydrochloride, 0.9% normal saline
- Where
- Egypt
- Volunteers
- 102 people
- Sponsor
- Assiut University
Hypotension
A Novel Closed-loop Integrated System for the Maintenance of Haemodynamic Stability
Hypotension occurs commonly during spinal anaesthesia for caesarean section with maternal and fetal adverse effects. The investigators developed a double-vasopressor automated system incorporating continuous non-invasive…
- Trial name
- DIVA (NCT02277730)
- Testing
- vasopressor delivery automated system, phenylephrine, ephedrine
- Where
- Singapore
- Volunteers
- 252 people
- Sponsor
- KK Women's and Children's Hospital
Intracranial Hypotension
Postoperative Changes in Optic Nerve Sheath Diameter in Patients Undergoing Spinal Anesthesia for Cesarean Delivery
This is observational study. The investigator will measure optic nerve sheath diameter by ultrasound on the eye after cesarean section under spinal anesthesia.
- Trial name
- NCT04301830
- Volunteers
- 50 people
- Sponsor
- SMG-SNU Boramae Medical Center
Effects of; Anesthesia, Spinal and Epidural, in Pregnancy
Leg Elevation for Prevention of Post Spinal Hypotension in Cesarean Section
Prospective trial including full term parturients scheduled for a cesarean section under spinal anesthesia. patients are being randomly assigned into 2 groups: LE group: will be positioned in 15° left tilt with leg elevation with…
- Trial name
- NCT03488277
- Testing
- leg elevation
- Where
- Tunisia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mongi Slim Hospital
Regional Block
Quadratus Lumborum Block Type 2 Versus Posterior Transversus Abdominus Plane Block
This patient population are at risk of adverse effects secondary to inadequate pain management such as inadequate maternal bonding and late ambulation.
- Trial name
- quadratus (NCT04773730)
- Testing
- Posterior transversus abdominus plane block, Quadratus lumborum block type 2
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Cesarean Section
Predictability of Preoperative Carotid Artery Corrected Flow Time for Hypotension After Spinal Anesthesia in Patients Undergoing Cesarean Section
The purpose of this study was to investigate the incidence of hypotension after spinal anesthesia in patients undergoing cesarean section as predicted by preoperative carotid artery corrected flow time measured by Doppler…
- Trial name
- NCT03631329
- Testing
- Doppler sonographic measurement
- Where
- South Korea
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Caesarean Section
The Effect of Presence of Father in the Operating Room on Quality of Recovery of the Parturient
The presence of a partner to support the mother during cesarean and vaginal deliveries is a well-established practice in most countries worldwide.
- Trial name
- NCT07406607
- Testing
- Standard Care (No Partner Presence), Partner Presence in Operating Room
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Karamanoğlu Mehmetbey University
Pregnancy Induced Hypertension
Fractionated Vs Single Dose Injection for Spinal C-Section in Patients With Pregnancy-Induced Hypertension
The aim of this study was to compare haemodynamic changes, total dose of ephedrin requirement, and level of sensory blockade between fractionated dose and single dose spinal anesthesia injection in obstetric patients with…
- Trial name
- NCT03693638
- Testing
- Bupivacaine-fentanyl
- Where
- Indonesia
- Volunteers
- 42 people
- Sponsor
- Universitas Indonesia
Anesthesia; Adverse Effect, Spinal and Epidural
Prophylaxis Ephedrine or Ondansetron Prevents Hypotension After Spinal Anesthesia for Cesarean Section
Maternal hypotension after spinal anesthesia in parturients undergoing cesarean section is a very common problem leading to several complications to both patients and their babies.
- Trial name
- NCT02194192
- Testing
- Ondansetron, Ephedrine
- Where
- Thailand
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Full Term Pregnant Patients, Undergoing Lower Segment Caesarian Section
Comparison of Different Doses of Clonidine to Fentanyl as an Adjuvant to Bupivacaine 0.5% for Spinal Anesthesia
The purpose of this study is to evaluate the safety, quality and duration of block with the addition of Clonidine in different doses to 0.5% heavy bupivacaine, and to compare it with addition of Fentanyl to 0.5% heavy bupivacaine…
- Trial name
- NCT01205204
- Testing
- Fentanyl, Clonidine
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pravara Institute of Medical Sciences University
Pregnancy, Effects of; Anesthesia, Spinal and Epidural; in Pregnancy
Effect of Different Injection Speeds for Spinal Anaesthesia in Caesarean Section
The purpose of this study is to investigate if prolonging the speed of injection during spinal anaesthesia can reduce the incidence of hypotension and/or medication requirements thereby making it safer for the mother and foetus.
- Trial name
- NCT02275897
- Testing
- Slow Speed of spinal injection, Fast Speed of spinal injection
- Where
- Malaysia
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Malaysia
Post-Dural Puncture Headache
Effect of Altitude on Postdural Puncture Headache After Caesarean Delivery
The aim of this study is to examine the effects of altitude (high altitude versus low altitude) on incidence and severity of postural puncture headache (PDPH) following spinal anaesthesia for caesarean delivery.
- Trial name
- NCT05804448
- Where
- 2 sites in Nepal
- Volunteers
- 292 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Spinal Anesthesia, Cesarean Section
Fixed Dose Spinal Bupivacaine for Cesarean Delivery
The study is designed to compare the effectiveness of spinal anesthesia performed with fixed dose of hyperbaric bupivacaine regardless of patient's height and weight and anesthesia with the dose of bupivacaine that is adjusted to…
- Trial name
- SpinFix-Bupi (NCT03231436)
- Testing
- Fixed dose of 12.5mg bupivacaine, Height-adjusted dose of bupivacaine
- Where
- Poland
- Volunteers
- 140 people
- Sponsor
- Bartosz Horosz, MD
Hypotension
A Comparison of Intermittent Intravenous Boluses of Phenylephrine and Norepinephrine to Prevent Spinal-induced Hypotension in Cesarean Deliveries
Hypotension is a very common complication of spinal anesthesia for cesarean delivery, and can have unwanted side effects on both mother and fetus if not treated promptly.
- Trial name
- NCT02962986
- Testing
- Norepinephrine, Phenylephrine
- Where
- Canada
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Anesthesia, Spinal, Cesarean Section
Abdominal Circumference Measure in Caesarian Section
The goal of this observational study is to evaluate preoperative measures of abdominal circumference in patients admitted for a cesarean section.
- Trial name
- ACirCuS (NCT06357637)
- Testing
- Measure of abdominal circumference
- Where
- Morocco
- Volunteers
- 124 people
- Sponsor
- CHU Mohammed VI Marrakech