Clinical trials: Spinal Anesthesia for Cesarean Section
Anesthesia
Epidural Technique: Does it Really Matter to the Patient?
The main objective of this study will be to determine if the dural puncture epidural (DPE) provides superior analgesia and better patient satisfaction when compared to traditional epidurals for cesarean sections, and to also…
- Trial name
- NCT03539796
- Testing
- Dural puncture epidurals (DPE), Traditional epidurals (EPI), Combined-spinal epidural technique (CSE)
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Emory University
Spinal Anesthesia
Measuring Cerebrospinal Fluid (CSF) Glucose Levels in Patients Under Going an Elective Cesarean Section With Spinal Anesthesia
This study will determine the level of glucose (sugar) in the CSF (fluid that surrounds the spinal cord) in 30 subjects having spinal anesthesia for cesarean section using a bedside glucose meter.
- Trial name
- NCT01067560
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Hypothermia
Pre-warming Prevents Hypothermia in Elective Cesarean Section
Background: Hypothermia is common during general and regional anesthesia even when active warming measures are taken. The existing literature shows that, in pregnant patients, the use of forced air-warming during cesarean section…
- Trial name
- hypothermia (NCT02091466)
- Testing
- pre-warming
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Faculdade de Ciências Médicas da Santa Casa de São Paulo
Obstetric
Analgesic Efficacy of Transvers Abdominis Plane Block and Transversalis Fascia Plane Block in Cesarean Section
This study was designed as a prospective, randomized observational clinical trial. A total of 90 adult women were included in the study performed elective cesarean section.
- Trial name
- NCT06386978
- Testing
- Transverse Facia Plane Block (TAP Block), Transversalis Facia Plane Block (TFP Block), Control
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Neonatal Cerebral Oxygenation, Cesarean Section
Effects of Spinal Versus General Anesthesia on Neonatal Cerebral Oxygenation During Cesarean Section
This prospective observational study evaluates and compares the effects of spinal and general anesthesia techniques used during elective cesarean section on neonatal cerebral regional oxygen saturation (crSO₂) during the early…
- Trial name
- NEO-OXY-CS (NCT07477093)
- Testing
- No intervention (observational study)
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Akdeniz University Hospital
Glycopyrrolate, Post-spinal Hypotension
Effect of Glycopyrrolate on Vasopressors Requirement for Non-elective Caesarean Section Under Spinal Anaesthesia
This is prospective randomised double blind study conducted in parturients planned for non-elective caesarean section under spinal anaesthesia.
- Conditions
- Glycopyrrolate, Post-spinal Hypotension, Effect of Drug, Hemodynamic Instability
- Trial name
- NCT04401345
- Testing
- Glycopyrrolate 0.2 MG/ML, Normal saline
- Where
- Nepal
- Volunteers
- 258 people
- Sponsor
- Rajesh Deshar
Post Spinal Hypotension
Perfusion Index vs Positional Hemodynamic Changes to Predict Hypotension After Spinal Anaesthesia in Caesarean Section
Comparative Study between the Perfusion Index and Positional Haemodynamic Changes for Prediction of Hypotension after Spinal Anaesthesia in Caesarean Section
- Trial name
- NCT05587153
- Testing
- perfusion index in all parturient recruited for the study
- Where
- 2 sites in Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Non Elective Cesarean Section and Ketamine Analgesia
Analgesia Effects of Intravenous Ketamine After Spinal Anesthesia for Non-elective Cesarean Section
This randomized double blind study will be conducted in pregnant woman planned for non elective cesarean section under spinal anesthesia.
- Trial name
- NCT03450499
- Testing
- Ketamine
- Where
- Nepal
- Volunteers
- 80 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Postoperative Pain
Effect of TAP Block on Time Required for First Analgesic Dose After Cesarean Cection Under Spinal Anesthesia
While opioids are the mainstay for post-operative analgesia after caesarean section, they are associated with various side effects.
- Trial name
- NCT04623632
- Testing
- Transversus abdominus plane block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams Maternity Hospital
Health Care, Drugs
Hyperbaric Bupivacaine and Hyperbaric Levobupivacaine in C/S
Aim of the Study To compare the effects of hyperbaric bupivacaine plus fentanyl with hyperbaric levobupivacaine plus fentanyl on spinal block quality, haemodynamics and need for analgesics in patients undergoing elective cesarean…
- Trial name
- NCT02025374
- Testing
- Hyperbaric levobupivacaine, Hyperbaric bupivacaine % 0.5
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Balikesir University
Pregnancy Related, Cesarean Section Complications
Predictive Hemodynamic Monitoring During Elective Cesarean Section
Single shot spinal anesthesia (SA) is the most commonly used technique for Caesarean section (CS) . SA is associated with maternal hypotension (Post Spinal Hypotension - PSH) often accompanied by nausea, vomiting, bradycardia and…
- Conditions
- Pregnancy Related, Cesarean Section Complications, Hypotension on Induction, Anesthesia Complication
- Trial name
- PREDICTION (NCT06729827)
- Testing
- Hypotension prediction Index - HPI
- Where
- Italy
- Volunteers
- 102 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Cesarean Section, Spinal Anesthesia
Comparison of Three Different Doses of Intrathecal Morphine for Analgesia After Cesarean Section
In our study, It was aimed to determine the dose of morphine that provides the most effective analgesia with the least incidence of side effects in the postoperative period.
- Conditions
- Cesarean Section, Spinal Anesthesia, Postoperative Analgesia
- Trial name
- NCT05317572
- Testing
- 80 mcg intrathecal morphine, 120 mcg intrathecal morphine, 160 mcg intrathecal morphine
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Pregnancy, Labor Pain
Does Ultrasound of the Spine Improve Labor Epidurals/Spinal Anesthesia in Obstetric Patients?
The investigators are interested in determining the utility of ultrasound of the spine for labor epidurals or spinal anesthesia for women in labor or having a cesarean delivery.
- Trial name
- NCT01243216
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Pulmonary Edema
a Comparison Between the Effects of Crystalloids and Colloids on Lung Ultrasound
This study is designed to compare the effect of crystalloids and colloids on lung ultrasound score in preeclapmtic pregnant cases undergoing spinal anesthesia for caesarean section Objectives: To identify ideal fluid in order to…
- Trial name
- NCT05505708
- Testing
- hydroxyethyl starch in sodium chloride injection Brand Name: Voluven, saline solution
- Where
- Egypt
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Dexmedetomidine
Comparing Doses of Intrathecal Dexmedetomidine
To compare the duration of sensory and motor blockade produced by two different intrathecal doses of dexmedetomidine (5 µg and 10 µg) when added to hyperbaric bupivacaine in patients undergoing elective cesarean section
- Trial name
- NCT07395271
- Testing
- Dexmedetomidine 5 mcg, Dexmedetomidine 10 mcg
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Bahria International Hospital
Cesarean Section, Obese Parturient
"Ultrasound vs. Landmark Technique for Spinal Anesthesia in Obese Women Undergoing Cesarean Section"
The goal of this clinical trial is to evaluate whether the ultrasound-assisted technique improves the accuracy and safety of spinal anesthesia compared to the traditional landmark technique in obese women undergoing a cesarean…
- Conditions
- Cesarean Section, Obese Parturient, Ultrasound Guided Subarachnoid Block
- Trial name
- NCT07601542
- Testing
- Landmark-Guided Spinal Anesthesia, Ultrasound-Assisted Spinal Anesthesia
- Where
- Bangladesh
- Volunteers
- 60 people
- Sponsor
- Bangladesh Medical University
Outcome
Intensive Versus Standard Treatment for Spinal Anesthesia-induced Hypotension
The objective of this study is to investigate the impact of varying maternal blood pressure maintenance targets on neonatal outcomes following cesarean section.
- Trial name
- NCT06151483
- Testing
- Alpha-Agonist, α-adrenergic receptor agonist
- Where
- China
- Volunteers
- 1,184 people
- Sponsor
- General Hospital of Ningxia Medical University
Twin Pregnancy, Neonate
Neonatal Outcomes in Twin Pregnancies
Multiple pregnancies are associated with increased maternal and fetal risks compared to singleton pregnancies. Additionally, the cesarean section rate is quite high in multiple pregnancies.
- Trial name
- NCT05104255
- Testing
- Spinal anesthesia, General anesthesia
- Volunteers
- 527 people, healthy volunteers welcome
- Sponsor
- Derince Training and Research Hospital
Complications; Cesarean Section
Use of Intrathecal Fentanyl and Development of Hyperalgesia in Patients Undergoing Elective Cesarean
Opioid analgesic drugs are the main treatment of patients during anesthesia. Although highly effective, their use is not without problems. One is the increasing requirement of these address the same nociceptive stimulus.
- Trial name
- NCT02387060
- Testing
- H-Bupivacaine, Fentanyl
- Where
- Chile
- Volunteers
- 80 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Preoperative Neutrophil-to-Lymphocyte Ratio (NLR), Postdural Puncture Headache
Neutrophil to Lymphocyte Ratio and Postdural Headache
This study will aim to investigate whether systemic inflammatory markers-especially the neutrophil-to-lymphocyte ratio (NLR)-obtained from preoperative complete blood counts can predict the development of post-dural puncture…
- Trial name
- NCT07075874
- Testing
- PDPH
- Where
- Turkey (Türkiye)
- Volunteers
- 821 people
- Sponsor
- Istinye University