Clinical trials: Spinal Anesthesia for Cesarean Section
Anesthesia; Adverse Effect, Spinal and Epidural
Prophylaxis Ephedrine or Ondansetron Prevents Hypotension After Spinal Anesthesia for Cesarean Section
Maternal hypotension after spinal anesthesia in parturients undergoing cesarean section is a very common problem leading to several complications to both patients and their babies.
- Trial name
- NCT02194192
- Testing
- Ondansetron, Ephedrine
- Where
- Thailand
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Pain, Acute
Intrathecal Midazolam, Fentanyl and Nalbuphine as Adjuvants to Bupivacaine in Spinal Anesthesia for Cesarean Section
The main limitations of spinal anesthesia are its short duration of action and do not provide prolonged postoperative analgesia when it is performed only with local anesthetics.
- Trial name
- NCT04932083
- Testing
- Bupivacaine, Fentanyl, Nalbuphine
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Benha University
Cesarean Section
The Effects of a Head Elevated Ramped Position During Elective Cesarean Delivery After Combined Spinal Epidural (CSE) Anesthesia
This study will randomly allocate 180 women undergoing elective C-sections under combined spinal epidural (CSE) Anesthesia at BC Women's Hospital to one of three groups: Standard Pillow under Head (Control), Head Elevated in…
- Trial name
- NCT01161693
- Testing
- TROOP® elevation pillow
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Caesarean Section, Anesthesia; Reaction
The Effects of Different Anesthetic Techniques on QT, Corrected QT (QTc), and P Wave Dispersions in Cesarean Section
This study evaluates the effects of different anesthetic techniques on QT, QTc, and Pwd in cesarean section. Half of participants received general anesthesia, while the other half received spinal anesthesia Electrocardiography…
- Trial name
- NCT03134677
- Testing
- Bupivacaine, Sevoflurane
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Trakya University
Anesthesia, Spinal, Cesarean Section
Combined Colloid Preload And Crystalloid Coload Versus Crystalloid Coload During Spinal Anesthesia for Cesarean Delivery
The study will compare one technique of fluid administration (combined colloid preload and crystalloid colaod) with another one (crystalloid coload) during elective cesarean delivery performed under spinal anesthesia.
- Trial name
- NCT02961842
- Testing
- 500 mL Colloid Preload, Spinal Anesthesia, Intrathecal Bupivacaine
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Mansoura University
Pregnant Women, Cesarean Birth
QTc Interval in Cesarean Section Patients
The aim of this clinical study is to determine which type of anesthesia has the least effect on the electrical activity of the heart in pregnant women undergoing cesarean section.
- Trial name
- NCT07524296
- Testing
- QT and QTc interval
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Haseki Training and Research Hospital
Regional Anesthesia Morbidity, Cesarean Section Complications
Height Adjusted Versus Standardized Dose of Bupivacaine for Spinal Anesthesia
General anesthesia during pregnancy is associated with several major risks including unanticipated difficult airway, pulmonary aspiration, and specific anesthetic effects on the newborn.
- Conditions
- Regional Anesthesia Morbidity, Cesarean Section Complications, Local Anesthetic Complication
- Trial name
- RAMCES (NCT05233462)
- Testing
- standardized dose, adjusted dose
- Where
- France
- Volunteers
- 250 people
- Sponsor
- University Hospital, Caen
Acute Pain
Clinical Efficacy of Prophylactic Intravenous Neostigmine and Atropine in Preventing Post-Dural Puncture Headache Among Parturient Undergoing Spinal Anesthesia for Cesarean Section: A Double-blind Randomized Placebo-controlled Trial
Post dural puncture headache is a distressing issue, many measures tried to treat symptoms but few delt with prevention.
- Trial name
- NCT06493838
- Testing
- intravenous 50 mL of saline injection of 0.9% after umbilical cord clamping., Neostigmine 20μg/kg (Neostigmine Methylsulphate 0.5 mg, Amriya Pharm.Ind.) and atropine 0.01 mg/kg (diluted in 50 ml saline; 0.9% for 10 min) following umbilical cord clamping.
- Volunteers
- 180 people
- Sponsor
- Minia University
Pain, Postoperative, Postoperative Nausea and Vomiting
Dexamethasone for Post-cesarean Delivery Pain
The purpose of this study is to compare post-cesarean section consumption of pain medication between two groups of patients undergoing scheduled cesarean section at term gestation who receive a single-dose of intraoperative…
- Trial name
- NCT01812057
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Duke University
Anesthesia; Adverse Effect, Spinal and Epidural, Hypotension
Ephedrine vs. Nor Epinephrine Infusion in Preventing Hypotension After Spinal Anesthesia for Cesarean Section
The purpose of the study is to determine if norepinephrine is more effective as a continuous intravenous (IV) infusion compared to continuous IV ephedrine associated with crystalloid loading for maintaining blood pressure during…
- Conditions
- Anesthesia; Adverse Effect, Spinal and Epidural, Hypotension, Complications; Cesarean Section
- Trial name
- NCT02477501
- Testing
- Norepinephrine, Ephedrine
- Where
- Tunisia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar
Hypotension, Hypertension
Norepinephrine ED90 Bolus After Spinal Anesthesia in Cesarean Section
The investigators are aiming to determine what is the effective intravenous dose required of an initial bolus of norepinephrine prior to a maintenance infusion to prevent a 20% decrease in maternal blood pressure from baseline…
- Conditions
- Hypotension, Hypertension, Nausea, Pain
- Trial name
- NCT06574555
- Testing
- Norepinephrine
- Where
- Chile
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Anesthesia, Spinal, Cesarean Section
Post Spinal Anesthesia Hypotension and Preoperative Hydration
Study of the impact of preoperative oral rehydration on the incidence of spinal anesthesia-induced hypotension for scheduled cesarean section.
- Trial name
- NCT04450667
- Testing
- Nutricia PreOp
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Brugmann University Hospital
Hypotension
Effect of Position During Spinal Anesthesia on Hemodynamic Change in Cesarean Section
Hypotension is the most common complications after spinal anesthesia especially in pregnant patients who undergoing cesarean section. Position during spinal anesthesia may be altering the hemodynamic.
- Trial name
- NCT02253381
- Testing
- Right, Left
- Where
- Thailand
- Volunteers
- 140 people
- Sponsor
- Prince of Songkla University
Maternal Hypotension Associated With Spinal Anesthesia During Cesarean Section
The Effect of Compression Stockings and Leg Elevation on Hemodynamic Stability in Elective Cesarean Sections Under Spinal Anesthesia: A Single-Blind Randomized Controlled Trial
Aim: This study aimed to evaluate the effects of compression stockings and leg elevation on maternal intraoperative hypotension, vasopressor requirement, and neonatal well-being parameters in women undergoing elective cesarean…
- Trial name
- NCT07534891
- Testing
- compression stockings, Leg elevation
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Seçil Yavaş
Hypotension
Efficacy of Voluven® for the Prevention of Hypotension During Spinal Anesthesia for Cesarean Section
The aim of the study is to evaluate the efficacy of Voluven® in the prevention of maternal hypotension in women undergoing spinal anesthesia for cesarean section
- Trial name
- CAESAR (NCT00694343)
- Testing
- HES 130/0.4 (6%) in sodium chloride (solution for infusion), Ringer's Lactate solution
- Where
- 14 sites in France
- Volunteers
- 167 people
- Sponsor
- Fresenius Kabi
Aortocaval Compression, Fetal Acidosis
Neonatal Acid-Base Status After C Section With Maternal Tilt vs. Supine
This study aims to compare the neonatal acid-base status of women who remain supine horizontal, with women who are tilted to the left side by 15° during elective cesarean delivery at term under spinal anesthesia, with systolic BP…
- Trial name
- NCT02243423
- Testing
- SUPINE, TILT
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Columbia University
Pain, Obesity
Effect of Body Mass Index on the Dose of Intrathecal Hyperbaric Bupivacaine for Elective Cesarean Section
Combined spinal - epidural (CSE) anesthesia is a well established technique used for elective Cesarean section. As its name suggests, it combines two anesthesia techniques - spinal and epidural.
- Trial name
- NCT00403663
- Testing
- bupivacaine 0.75% with fentanyl and morphine
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Breastfeeding
Evaluation of Breastfeeding Success and Self-Efficacy in Mothers Giving Birth Via Vaginal Delivery or Cesarean Section
This cross-sectional observational study was conducted to compare breastfeeding success and breastfeeding self-efficacy levels of mothers who gave birth via vaginal delivery (spontaneous or via epidural analgesia) or cesarean…
- Trial name
- NCT05106634
- Where
- Turkey (Türkiye)
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Full Term Pregnant Patients, Undergoing Lower Segment Caesarian Section
Comparison of Different Doses of Clonidine to Fentanyl as an Adjuvant to Bupivacaine 0.5% for Spinal Anesthesia
The purpose of this study is to evaluate the safety, quality and duration of block with the addition of Clonidine in different doses to 0.5% heavy bupivacaine, and to compare it with addition of Fentanyl to 0.5% heavy bupivacaine…
- Trial name
- NCT01205204
- Testing
- Fentanyl, Clonidine
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pravara Institute of Medical Sciences University
Anesthesia
Fentanyl Versus Morphine in Spinal Anesthesia for Caesarian Section - Study on Analgesia, Side Effects and Patient 's Satisfaction
Intrathecal morphine and fentanyl are used for anesthesia and perioperative pain management in caesarian section. Despite the fact that spinal Fentanyl is better tolerated, might not be enough for postoperative pain control.
- Trial name
- FvMinSA (NCT05533229)
- Testing
- Fentanyl, Morphine
- Where
- Romania
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Dr. Mihai Octavian Botea