Clinical trials: Spinal Anesthesia for Cesarean Section
Neonatal Cerebral Oxygenation, Cesarean Section
Effects of Spinal Versus General Anesthesia on Neonatal Cerebral Oxygenation During Cesarean Section
This prospective observational study evaluates and compares the effects of spinal and general anesthesia techniques used during elective cesarean section on neonatal cerebral regional oxygen saturation (crSO₂) during the early…
- Trial name
- NEO-OXY-CS (NCT07477093)
- Testing
- No intervention (observational study)
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Akdeniz University Hospital
Hypotension
Up-Down Determination of the ED90 of Metaraminol to Treat Hypotension During Cesarean Section
The purpose of this study is to find the best dose of metaraminol to be used in patients during elective cesarean sections.
- Trial name
- NCT01108874
- Testing
- Metaraminol
- Where
- Brazil
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Anesthesia, Obstetrical, Anesthesia, Spinal
Phenylephrine and Hypotension During Spinal Anesthesia for Cesarean Section
Pregnant women with a positive preoperative Supine stress test were found to be a subgroup at increased risk of symptomatic hypotension after spinal anesthesia
- Trial name
- NCT02958215
- Testing
- Phenylephrine
- Where
- Egypt
- Volunteers
- 980 people
- Sponsor
- Assiut University
Maternal Haemodynamic Stability
Maternal Haemodynamic Changes After Crystalloid Co-loading and Phenylephrine Versus Phenylephrine Alone During Spinal Anaesthesia for Elective Caesarean Delivery
Spinal anaesthesia is the anaesthetic technique of choice for elective caesarean delivery. Hypotension, a result of the decrease in systemic vascular resistance caused by spinal anaesthesia, is a frequent complication occurring…
- Trial name
- NICOM-USB (NCT04026685)
- Testing
- Phenylephrine infusion, Phenylephrine infusion and Ringer-Acetate bolus
- Where
- Switzerland
- Volunteers
- 66 people
- Sponsor
- University Hospital, Basel, Switzerland
Hypotension
Transcutaneous Electrical Acupoint Stimulation(TEAS) for Hypotension After Spinal Anesthesia in Parturients
The purpose of this study is to compare the effect of TEAS on hypotension after spinal anesthesia in patients undergoing cesarean section
- Trial name
- THSAP (NCT01930227)
- Testing
- TEAS, Non-acupoint stimulation
- Where
- 2 sites in China
- Volunteers
- 150 people
- Sponsor
- wangqiang
Hypotension, Spinal Block
Epinephrine Vs Norepinephrine Infusion During Caesarean Delivery
Epinephrine is a well-known vasoactive agent in medical practice. However, its use is obstetric population is still scanty. Few studies evaluated the use of epinephrine during Cesarean delivery and a recent randomized controlled…
- Conditions
- Hypotension, Spinal Block, Cesarean Section
- Trial name
- NCT06512402
- Testing
- Norepinephrine, Epinephrine
- Where
- Egypt
- Volunteers
- 212 people
- Sponsor
- Cairo University
Anesthesia, Pregnancy Related
Upper vs Lower Extremity BP in Spinal Cesarean Using ClearSight
This is a single-center, prospective observational study in patients undergoing cesarean delivery under spinal or combined spinal-epidural anesthesia.
- Conditions
- Anesthesia, Pregnancy Related, Blockades Neuromuscular
- Trial name
- NCT07685730
- Testing
- ClearSight
- Where
- United States
- Volunteers
- 327 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Cesarean Section, Spinal Anesthesia
Effects of Crystal Solution and Colloid Solution on Mother and Fetus
Comparison of the effects of crystal solution (lactic acid Ringer's solution) and colloid solution (hydroxyethyl starch) on mother and fetus after cesarean section
- Conditions
- Cesarean Section, Spinal Anesthesia, Parturition
- Trial name
- NCT04432675
- Testing
- hydroxyethl starch, Lactated Ringer's solution
- Where
- China
- Volunteers
- 100 people
- Sponsor
- China International Neuroscience Institution
Cesarean Section Complications, Hypotension
Prediction of Hypotension Using Perfusion Index and Pleth Variability Index After Spinal Anesthesia for C/S
Spinal anesthesia for caesarean section is associated with a decrease in systemic vascular resistance and cardiac output and may cause hypotension in a significant portion of the parturients.
- Conditions
- Cesarean Section Complications, Hypotension, Spinal Anesthesia, Perfusion Index
- Trial name
- NCT03864692
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Cesarean Section, Anesthesia,Spinal
Atropine to Prevent Nausea and Vomiting After Spinal Anesthesia for Caesarean Section
The aim of this study is to assess the efficacy of atropine in preventing nausea and vomiting after spinal anesthesia with local anesthetic and morphine for elective Caesarean section.
- Conditions
- Cesarean Section, Anesthesia,Spinal, Postoperative Nausea and Vomiting
- Trial name
- NCT00921102
- Testing
- Bupivacaine, Morphine, Isotonic saline solution
- Where
- 2 sites in Italy
- Volunteers
- 216 people
- Sponsor
- University of Parma
Postoperative Pain
Continuous Pre-uterine Wound Infiltration Versus Intrathecal Morphine for Postoperative Analgesia After Cesarean Section
The cesarean section is considered as a painful surgery during the post operative period. Mothers may need to move immediately after the surgery to take care of their babies.
- Trial name
- NCT02279628
- Testing
- Ropivacaine, Morphine
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Central Hospital, Nancy, France
Postoperative Pain
Intravenous Ketamine and Postoperative Pain Following Cesarean Section.
The purpose of this study is to investigate the analgesic effect of low-dose intravenous ketamine in pregnant mothers undergoing cesarean section under Bupivacaine spinal anesthesia.
- Trial name
- NCT03018301
- Testing
- Ketamine, Normal saline
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Post-Dural Puncture Headache
Contribution of Ondansetron to Preventing Post-Dural Puncture Headaches Following Spinal Anesthesia
A prospective, bicentric, randomized, double-blind controlled study including parturients scheduled for elective caesarean delivery under spinal anaesthesia and randomized and assigned to one of the two groups: Group O…
- Trial name
- OPDPH (NCT06444737)
- Testing
- Intravenous ondansetron, Intravenous normal saline
- Where
- Tunisia
- Volunteers
- 300 people
- Sponsor
- Mongi Slim Hospital
Twin Pregnancy, Neonate
Neonatal Outcomes in Twin Pregnancies
Multiple pregnancies are associated with increased maternal and fetal risks compared to singleton pregnancies. Additionally, the cesarean section rate is quite high in multiple pregnancies.
- Trial name
- NCT05104255
- Testing
- Spinal anesthesia, General anesthesia
- Volunteers
- 527 people, healthy volunteers welcome
- Sponsor
- Derince Training and Research Hospital
Caesarean Section, Spinal Anesthesia
Effect of Bilateral Quadratus Lumborum Block for Pain Relief in Patients With Cesarean Section
Cesarean section commonly induces moderate to severe pain for 48 hours. These patients have additional compelling reasons to provide adequate pain relief as early mobilization is a key factor to prevent the risk of thromboembolic…
- Conditions
- Caesarean Section, Spinal Anesthesia, Quadratus Lumborum Block, Analgesia
- Trial name
- NCT03199170
- Testing
- Intrathecal morphine, Bilateral Quadratus Lumborum Block, Intrathecal morphine with bilateral Quadratus Lumborum Block
- Where
- Thailand
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Pruritus Caused by Drug
Ondansetron Use for Preventing Pruritus in Patients Undergoing Cesarean Section
Opioids are often added with a local anesthetic to enhance the duration and quality of spinal anesthesia for cesarean delivery patients.
- Trial name
- NCT06297499
- Testing
- Ondansetron 8mg
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Cesarean Section Complications, Spinal Anesthetic Toxicity
Comparison of Vasopressor Boluses for Management of Hypotension After Spinal Anesthesia
In this study the investigators will compare the efficacy and side effects of two doses of norepinephrine bolus (6 mcg and 10 mcg) in management of maternal hypotensive episode after subarachnoid block during Cesarean delivery.
- Trial name
- NCT03712111
- Testing
- Norepinephrine 6 mcg, Norepinephrine 10 mcg, Bupivacaine Hydrochloride
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Cairo University
Epidural Anesthesia, Spinal Ultrasound
Ultrasound Versus Palpation for Epidural Catheterization
The study will assess the benefit of using spinal ultrasound before epidural catheter insertion compared to the conventional palpation technique in women undergoing cesarean section.
- Trial name
- NCT02410226
- Testing
- Double-space combined spinal-epidural anesthesia, Preprocedure spinal ultrasound
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Mansoura University
Cesarean Section, Hypotension
Effect of Oxytocin Bolus Versus Slow Infusion on Haemodynamic Stability During Caesarean Section Under Spinal Anaesthesia
This study compares two standard ways of giving oxytocin (a medicine that helps the uterus contract) after the baby is born during a planned caesarean section performed under spinal anaesthesia.
- Conditions
- Cesarean Section, Hypotension, Postpartum Hemorrhage, Spinal Anesthesia
- Trial name
- NCT07784478
- Testing
- Oxytocin
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Khyber Girls Medical College
Cesarean Section Complications, Spinal Anesthetic Complications
Hemodynamic Effect of Left Tilting in Cesarean Delivery
The aim of this work is to investigate the effect of different angles of lateral tilt on the maternal hemodynamics before and after subarachnoid block
- Trial name
- NCT03181776
- Testing
- left lateral tilting in 15 degrees, left lateral tilting in 30 degrees, supine position
- Where
- Egypt
- Volunteers
- 61 people
- Sponsor
- Cairo University