Clinical trials: Spinal Anesthetic Complications
Postoperative Cognitive Complications
Spinal Anesthesia Vs. Neve Block in Risk of Cognitive Decline
Hip fracture is a potentially devastating event, and serious surgical and medical complications occur frequently especially for elderly patients. Delirium is one of the common complications after hip surgery.
- Trial name
- NCT06963229
- Testing
- Spinal Anesthesia (bupivacaine), Peripheral Nerve Block
- Where
- Lebanon
- Volunteers
- 50 people
- Sponsor
- Makassed General Hospital
Anesthesia; Adverse Effect
Perfusion Index Changes in Cardiovascular Autonom Neuropathia Type-2 Dm Whit Spinal Anesthesia
Cardiovascular autonomic neuropathy in diabetic patients, hypertension, sympathovagal imbalance, orthostatic hypotension, painless myocardial infarction, ischemia, left ventricular dysfunction, cardiac sympathetic and…
- Trial name
- PI (NCT03869775)
- Testing
- perfusion index monitor, ewing test
- Where
- Turkey (Türkiye)
- Volunteers
- 240 people
- Sponsor
- Erzincan University
Cesarean Section Complications, Hypotension
Prediction of Hypotension Using Perfusion Index and Pleth Variability Index After Spinal Anesthesia for C/S
Spinal anesthesia for caesarean section is associated with a decrease in systemic vascular resistance and cardiac output and may cause hypotension in a significant portion of the parturients.
- Conditions
- Cesarean Section Complications, Hypotension, Spinal Anesthesia, Perfusion Index
- Trial name
- NCT03864692
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Cesarean Section, Anesthesia,Spinal
Atropine to Prevent Nausea and Vomiting After Spinal Anesthesia for Caesarean Section
The aim of this study is to assess the efficacy of atropine in preventing nausea and vomiting after spinal anesthesia with local anesthetic and morphine for elective Caesarean section.
- Conditions
- Cesarean Section, Anesthesia,Spinal, Postoperative Nausea and Vomiting
- Trial name
- NCT00921102
- Testing
- Bupivacaine, Morphine, Isotonic saline solution
- Where
- 2 sites in Italy
- Volunteers
- 216 people
- Sponsor
- University of Parma
Postoperative Pain
Continuous Pre-uterine Wound Infiltration Versus Intrathecal Morphine for Postoperative Analgesia After Cesarean Section
The cesarean section is considered as a painful surgery during the post operative period. Mothers may need to move immediately after the surgery to take care of their babies.
- Trial name
- NCT02279628
- Testing
- Ropivacaine, Morphine
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Central Hospital, Nancy, France
Postoperative Pain
Intravenous Ketamine and Postoperative Pain Following Cesarean Section.
The purpose of this study is to investigate the analgesic effect of low-dose intravenous ketamine in pregnant mothers undergoing cesarean section under Bupivacaine spinal anesthesia.
- Trial name
- NCT03018301
- Testing
- Ketamine, Normal saline
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Placenta Accreta Spectrum
Spinal Versus General Anesthesia in Pregnancies With Placenta Accreta Spectrum: A Retrospective Comparative Study
Placenta accreta spectrum (PAS) is a serious pregnancy complication in which the placenta grows abnormally into the uterine wall.
- Trial name
- SAGA-PAS (NCT07406841)
- Testing
- spinal anesthesia, General Anesthesia
- Volunteers
- 50 people
- Sponsor
- Gaziantep City Hospital
Gabapentin, Tramadol
Preemptive Oral Gabapentin and Tramadol on Postoperative Pain After Knee Arthroscopy
The aim of this study to evaluate the effect of preemptive oral gabapentin versus tramadol on postoperative pain after knee arthroscopy under spinal anesthesia.
- Conditions
- Gabapentin, Tramadol, Postoperative Pain, Knee Arthroscopy
- Trial name
- NCT06112223
- Testing
- Gabapentin, Tramadol
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University
Caesarean Section, Spinal Anesthesia
Effect of Bilateral Quadratus Lumborum Block for Pain Relief in Patients With Cesarean Section
Cesarean section commonly induces moderate to severe pain for 48 hours. These patients have additional compelling reasons to provide adequate pain relief as early mobilization is a key factor to prevent the risk of thromboembolic…
- Conditions
- Caesarean Section, Spinal Anesthesia, Quadratus Lumborum Block, Analgesia
- Trial name
- NCT03199170
- Testing
- Intrathecal morphine, Bilateral Quadratus Lumborum Block, Intrathecal morphine with bilateral Quadratus Lumborum Block
- Where
- Thailand
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Spinal Anesthetic Toxicity, Inferior Vena Cava Abnormality
Transthoracic Echocardiography of Inferior Vena Cava Before Spinal Anesthesia Can Predict Hypotension
Study Protocol: Outcome Measurements Primary Outcome The main outcome will be the preoperative performance of the dIVCmax/IVCCI ratio to foresee the incidence of hypotension after spinal anesthesia in a greater extent to that of…
- Conditions
- Spinal Anesthetic Toxicity, Inferior Vena Cava Abnormality, Intraoperative Complications
- Trial name
- NCT03266250
- Testing
- spinal anesthesia
- Where
- Greece
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Postoperative Pain
Dexmedetomidine Versus Magnesium Sulfate Infusion During Spinal Anesthesia
The aim of this work is to compare the hemodynamic and analgesic properties of Dexmedetomidine and Magnesium sulphate infusion in lower abdominal surgery.
- Trial name
- NCT03640390
- Testing
- Dexmedetomidine, Magnesium Sulphate, Normal saline
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Femoral Neck Fractures, Blood Loss, Surgical
Effect of Regional Anesthesia Techniques on Perioperative Blood Loss in Femoral Neck Fracture Surgery
This retrospective observational study evaluates the effect of different regional anesthesia techniques on perioperative blood loss in patients undergoing femoral neck fracture surgery.
- Conditions
- Femoral Neck Fractures, Blood Loss, Surgical, Postoperative Pain
- Trial name
- NCT07702084
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Spinal Fusion, Nausea and Vomiting, Postoperative
Aprepitant Treatment to Prevent Postoperative Nausea and Vomiting in Children Undergoing Scoliosis Surgery
This research trial will measure how useful Aprepitant is in preventing nausea and vomiting in children having surgery to correct scoliosis (curvature of the spine).
- Conditions
- Spinal Fusion, Nausea and Vomiting, Postoperative, Anesthesia
- Trial name
- NCT06357234
- Testing
- Aprepitant
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- IWK Health Centre
Cesarean Section Complications, Spinal Anesthetic Toxicity
Comparison of Vasopressor Boluses for Management of Hypotension After Spinal Anesthesia
In this study the investigators will compare the efficacy and side effects of two doses of norepinephrine bolus (6 mcg and 10 mcg) in management of maternal hypotensive episode after subarachnoid block during Cesarean delivery.
- Trial name
- NCT03712111
- Testing
- Norepinephrine 6 mcg, Norepinephrine 10 mcg, Bupivacaine Hydrochloride
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Cairo University
Anesthesia, Anesthesia Complication
Sedation Complications in Urology During Spinal Anesthesia With Dexmedetomidine or Midazolam Regarding OSA Risk
Light to moderate sedation is recommended during surgery with spinal anesthesia . This study is exploring which sedation drug is better, midazolam or dexmedetomidine for transurethral resection of bladder and prostate in patients…
- Conditions
- Anesthesia, Anesthesia Complication, Osa Syndrome, Transurethral Resection of Prostate
- Trial name
- NCT04817033
- Testing
- Spinal anesthesia with intraoperative dexmedetomidine sedation, Spinal anesthesia with intraoperative midazolam sedation, Dexmedetomidine
- Where
- Croatia
- Volunteers
- 115 people
- Sponsor
- University Hospital of Split
Urologic Neoplasms, Benign Prostatic Hyperplasia
Spinal Versus General Anesthesia in Open Simple Prostatectomy
Open simple prostatectomy is still performed for selected patients with benign prostatic hyperplasia, particularly in cases with large prostate volume.
- Conditions
- Urologic Neoplasms, Benign Prostatic Hyperplasia, Anesthesia
- Trial name
- NCT07643415
- Testing
- Spinal anesthesia, General anesthesia
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Hitit University
Cesarean Section, Hypotension
Effect of Oxytocin Bolus Versus Slow Infusion on Haemodynamic Stability During Caesarean Section Under Spinal Anaesthesia
This study compares two standard ways of giving oxytocin (a medicine that helps the uterus contract) after the baby is born during a planned caesarean section performed under spinal anaesthesia.
- Conditions
- Cesarean Section, Hypotension, Postpartum Hemorrhage, Spinal Anesthesia
- Trial name
- NCT07784478
- Testing
- Oxytocin
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Khyber Girls Medical College
Cesarean Section Complications, Spinal Anesthetic Complications
Hemodynamic Effect of Left Tilting in Cesarean Delivery
The aim of this work is to investigate the effect of different angles of lateral tilt on the maternal hemodynamics before and after subarachnoid block
- Trial name
- NCT03181776
- Testing
- left lateral tilting in 15 degrees, left lateral tilting in 30 degrees, supine position
- Where
- Egypt
- Volunteers
- 61 people
- Sponsor
- Cairo University
Anesthetic Complication Spinal
Variable Rate Phenylephrine Infusion for Prevention of Spinal-induced Hypotension for Cesarean Delivery
Rapid administration of crystalloid immediately after induction of spinal anesthesia (coload) to be more effective in terms of managing hypotension as compared to administering crystalloid before spinal anesthesia (preload).
- Trial name
- NCT01378325
- Testing
- Phenylephrine, saline
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Postoperative Pain
Comparison of Pain Relief Duration With Dexmedetomidine Versus Fentanyl Added to Spinal Anesthesia in Patients Undergoing Lower Limb Orthopedic Surgery
The goal of this randomized clinical trial is to compare how long effective pain relief lasts when dexmedetomidine or fentanyl is added to hyperbaric bupivacaine during spinal anesthesia for lower limb orthopedic surgery.
- Trial name
- NCT07770542
- Testing
- Dexmedetomidine & Bupivacaine., fentanyl and bupivacaine
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Allama Iqbal Teaching Hospital