Clinical trials: Spinal Cord Injuries, completed
Spinal Cord Injuries, Paraplegia, Spinal
Transspinal Stimulation Plus Locomotor Training for SCI
Locomotor training is often used with the aim to improve corticospinal function and walking ability in individuals with Spinal Cord Injury.
- Conditions
- Spinal Cord Injuries, Paraplegia, Spinal, Tetraplegia/Tetraparesis, Paraplegia, Spastic
- Trial name
- NCT04807764
- Testing
- Standing transspinal stimulation followed by robotic gait training, Lying transspinal stimulation followed by robotic gait training
- Where
- 2 sites in United States
- Volunteers
- 14 people
- Sponsor
- City University of New York
Brain Injury, Cerebral Palsy
Combination Therapy of Cord Blood and G-CSF for Patients With Brain Injury or Neurodegenerative Disorders
This open label trial is conducted to investigate the efficacy and safety of the combination therapy of allogeneic umbilical cord blood (UCB) and granulocyte-colony stimulating factor (G-CSF) for patients with brain injury or…
- Conditions
- Brain Injury, Cerebral Palsy, Amyotrophic Lateral Sclerosis, Parkinson's Disease
- Trial name
- NCT02236065
- Testing
- Umbilical cord blood therapy, Filgrastim
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- MinYoung Kim, M.D.
Spinal Cord Injuries
Safety and Pharmacokinetics Study of Oral Lithium in Patients With Chronic Spinal Cord Injury
The current study is a phase I open-label clinical trial to examine plasma levels after oral lithium treatments in 20 subjects with chronic spinal cord injury.
- Trial name
- NCT00431171
- Testing
- Lithium carbonate
- Where
- China
- Volunteers
- 20 people
- Sponsor
- The University of Hong Kong
Communication Disorders
Adaptive and Individualized AAC
This project will test the feasibility of developing a smart augmentative or alternative communication (AAC) system that is effective in delivering communication capabilities that automatically adapt to the users' physical…
- Trial name
- NCT04247828
- Testing
- Experimental AAC, Generic AAC
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Altec Inc.
Spinal Cord Injury
Internet Self-Management for People With Intermittent Urinary Catheters
1. Design and develop web-based self-management intervention to improve catheter-related outcomes and quality of life in people with spinal cord injury (SCI). 2.
- Trial name
- Internet CIC (NCT02168465)
- Testing
- teaching self-management of an intermittent catheter
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Rochester
Spinal Cord Injury
Spinal Cord Stimulation for Spinal Cord Injury Patients - Regain Walk and Alleviate Pain
The study aims to examine the plausible interventional mechanisms underlying the effects of epidural spinal cord stimulation.
- Trial name
- NCT05433064
- Testing
- Epidural Stimulator
- Where
- Taiwan
- Volunteers
- 12 people
- Sponsor
- Buddhist Tzu Chi General Hospital
Spinal Cord Injury (SCI)
Trunk Balance and Functional Independence in Individuals With SCI
This study investigates the relationship between trunk balance, position sense, wheelchair skills, and functional independence in individuals with thoracic spinal cord injury.
- Trial name
- SCI (NCT06612112)
- Testing
- No Interventions
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Afyonkarahisar Health Sciences University
Spinal Cord Injuries, Paralysis
Adipose Stem Cells for Traumatic Spinal Cord Injury
The purpose of this study is to determine if mesenchymal stem cells (MSC) derived from the fat tissue can be safely administered into the cerebrospinal fluid (CSF) of patients with spinal cord injury.
- Trial name
- CELLTOP (NCT03308565)
- Testing
- Autologous, Adipose derived Mesenchymal Stem Cells
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Mohamad Bydon
Spinal Cord Injury, Neurogenic Lower Urinary Tract Dysfunction
Representation of the Bladder Innervation Using Diffusion Tensor Imaging Fiber Tracking With MRI - a Pilot Study
The exact innervation of the bladder and the changes after a spinal cord injury have been not yet been illustrated. Diffusion tensor imaging with magnetic resonance imaging is a new technique which can be used to visualize single…
- Trial name
- NCT02138201
- Where
- Switzerland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Swiss Paraplegic Research, Nottwil
Spinal Cord Injury, Paralysis
A Neuroprosthesis for Prolonged Standing After SCI Using Multi-Contact Peripheral Nerve Electrodes
The purpose of this study is to improve the performance of neuroprosthesis for standing after SCI by developing and testing new advanced methods that use multiple contact peripheral nerve electrodes to slow the onset of fatigue…
- Conditions
- Spinal Cord Injury, Paralysis, Tetraplegia, Paraplegia
- Trial name
- NCT01923662
- Testing
- IST-16 (16-Channel implanted stimulator-telemeter
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- VA Office of Research and Development
Syringomyelia
Study and Surgical Treatment of Syringomyelia
The goal of this study is to establish the mechanism(s) of progression of primarily spinal syringomyelia (PSS). Our preliminary study of syringomyelia emphasized syringomyelia associated with craniocervical junction abnormalities…
- Trial name
- NCT00011245
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Neuropathic Pain, Spinal Cord Injury
Effectiveness of Controlled-Release Morphine for Chronic Neuropathic Pain After Spinal Cord Injury
We would like to learn if a medicine called "modified-release morphine sulfate" (Avinza) helps reduce Spinal Cord Injury (SCI)-related pain that has lasted a long time.
- Trial name
- NCT00488969
- Testing
- Modified-release morphine
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Central Neuropathic Pain, Allodynia
Clinical Neuropharmacology of Pain in Spinal Cord Injury- Dextromethorphan/Lidocaine Combination Clinical Trial
This randomized, placebo-controlled, double-blind 4x4 crossover clinical trial was part of a larger NIH-funded study to evaluate the analgesic efficacy of multiple dose-combinations of chronic oral (PO) dextromethorphan and…
- Conditions
- Central Neuropathic Pain, Allodynia, Spinal Cord Injury
- Trial name
- NCT02218203
- Testing
- Dextromethorphan, Lidocaine
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Brigham and Women's Hospital
Spinal Cord Injuries
Muscle and Bone Changes After 6 Months of FES Cycling
The goal of this clinical trial is to assess the effectiveness of FES cycling in terms of changes morpho-functional characteristics of the leg muscles, training performance and bone trophism in 5 subjects with Spinal Cord Injury…
- Trial name
- FES-Bike (NCT06321172)
- Testing
- FES Bike
- Where
- Italy
- Volunteers
- 5 people
- Sponsor
- IRCCS Eugenio Medea
Spinal Cord Injuries
Minocycline and Perfusion Pressure Augmentation in Acute Spinal Cord Injury
While research in animal models of spinal cord injury have provided many promising insights, human studies have failed to produce effective therapies.
- Trial name
- NCT00559494
- Testing
- Minocycline, SCPP augmentation, SCPP control
- Where
- Canada
- Volunteers
- 52 people
- Sponsor
- University of Calgary
Spinal Cord Injuries, Tetraplegia
Human Factors Validation Testing of the Wandercraft Personal Exoskeleton
The goal of this interventional, national, prospective, open and monocentric study is to demonstrate that a personal exoskeleton can be used by the intended users without serious use errors or problems, for the intended uses and…
- Conditions
- Spinal Cord Injuries, Tetraplegia, Paraplegia
- Trial name
- ExoUser (NCT06715631)
- Testing
- Hands-free exoskeleton
- Where
- France
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Wandercraft
Spinal Cord Injury
Modified Yoga for Pulmonary Function and Quality of Life in Spinal Cord Injury Patients
This pilot interventional study evaluated whether adding wheelchair-adapted Modified Yoga Therapy to conventional physical rehabilitation could improve pulmonary function, respiratory muscle strength, and quality of life in…
- Trial name
- Leave blank (NCT07842003)
- Testing
- Conventional Physical Rehabilitation Therapy, Modified Yoga Therapy
- Where
- India
- Volunteers
- 29 people
- Sponsor
- Government (CL&SC) Spine Institute and Hospital, Ahmedabad
Paraplegia, Spinal Cord Injuries
Effect Of Magnetic Therapy In Bladder Dysfunction And Quality Of Life In Paraplegic Patients
Each study subject will undergo baseline urodynamic testing (UDS) at the beginning of the study to confirm the diagnosis of a neurogenic bladder with DSD and establish baseline bladder functions.
- Trial name
- NCT06169969
- Testing
- magnetic therapy
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Spinal Cord Injury, Cervical Spondylosis With Myelopathy
High-Resolution Diffusion Tensor Imaging (DTI) of the Cervical Spinal Cord in the Setting of Spinal Cord Injury (SCI)
The investigators propose a prospective study, designed to analyze the efficacy of High-Resolution Diffusion Tensor Imaging for accurately sensing white matter tracts in subjects with spinal cord injury.
- Conditions
- Spinal Cord Injury, Cervical Spondylosis With Myelopathy, Degenerative Disorder
- Trial name
- NCT01407705
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Utah
Spinal Cord Injuries
A Clinical Trial of Cognitive Multisensory Rehabilitation for Sensory and Motor Recovery in Adults With Spinal Cord Injury
To provide an effective treatment for recovery from paralysis and improved quality of life of veterans, military, and civilians with spinal cord injury/disorder (SCI/D).
- Trial name
- NCT05167032
- Testing
- Cognitive Multisensory Rehabilitation (CMR), Adaptive fitness
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Minnesota