Clinical trials: Spinal Cord Injury(SCI)
Urinary Retention, Neurogenic Bladder
Connected Catheter- Safety and Effectiveness Study
The Connected Catheter is a fully internal, urethral indwelling urinary prosthesis designed for improved bladder management in males with urinary retention disorders requiring catheterization.
- Conditions
- Urinary Retention, Neurogenic Bladder, Urologic Diseases
- Trial name
- NCT03843073
- Testing
- Connected Urinary Catheter
- Where
- 9 sites in United States
- Volunteers
- 9 people
- Sponsor
- Spinal Singularity
SCI - Spinal Cord Injury
Nutrition and Pain Study
The purpose of this research is to assess the effectiveness of a nutrition intervention on diet quality in managing pain in individuals with spinal cord injury (SCI).
- Trial name
- NCT07179588
- Testing
- Nutrition Education Program, Nutrition Counseling
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Miami
Spinal Cord Injury Cervical, Tetraplegia/Tetraparesis
Implantable Wireless Brain-Computer Interface Systems in Patients With Tetraplegia
Objectives of Study: This trial aims to evaluate the safety and efficacy of an implantable wireless brain-computer interface system in patients with tetraplegia resulting from spinal cord injury.
- Conditions
- Spinal Cord Injury Cervical, Tetraplegia/Tetraparesis, Spinal Cord Injuries (SCI)
- Trial name
- LEAP (NCT07784088)
- Testing
- IWBCIS
- Where
- China
- Volunteers
- 34 people
- Sponsor
- BCIFlex Medical Technology Co., Ltd.
Spinal Cord Injuries
Spinal Stimulation + FES-Assisted Cough Training in SCI
The overall objective of this proposal is to determine if transcutaneous spinal cord stimulation (tSCS) delivered concurrently with functional electrical stimulation (FES)-assisted cough training (FES-Cough) is an effective…
- Trial name
- NCT07683780
- Testing
- tSCS combined with FES-Cough
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Milap Sandhu
Spinal Cord Injury, Paraplegia
Safety of Autologous Human Schwann Cells (ahSC) in Subjects With Subacute SCI
The purpose of this study is to assess the safety of autologous human Schwann cells (ahSC) transplantation in subjects with subacute SCI.
- Trial name
- NCT01739023
- Testing
- Autologous Human Schwann Cells
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- W. Dalton Dietrich
Spinal Cord Injury
Evaluation of a Specialized Yoga Program for Persons With Spinal Cord Injury (SCI)
The purpose of this randomized controlled study is to evaluate psychological variables, mindfulness, and pain in the context of a specialized yoga program for individuals with SCI.
- Trial name
- SCI (NCT02656927)
- Testing
- Yoga Condition
- Volunteers
- 22 people
- Sponsor
- University Health Network, Toronto
Acute Spinal Cord Injury (SCI)
Additional Phase 3 Study of KP-100IT in Subjects With Acute Spinal Cord Injury
This is a Phase 3, multicenter, open-label, single-arm additional study to evaluate the efficacy of intrathecal KP-100IT in patients with acute spinal cord injury.
- Trial name
- NCT07722962
- Testing
- KP-100IT
- Where
- 3 sites in Japan
- Volunteers
- 10 people
- Sponsor
- Kringle Pharma, Inc.
Tetraplegia/Tetraparesis, Amyotrophic Lateral Sclerosis (ALS)
Control of Assistive Devices Via Brain-Computer Interface Technology
The CONVOY Study is a clinical trial designed to explore the feasibility of participants from the PRIME Study (NCT06429735) using the N1 Implant to control various assistive devices.
- Conditions
- Tetraplegia/Tetraparesis, Amyotrophic Lateral Sclerosis (ALS), Quadriplegia, Spinal Cord Injury (SCI)
- Trial name
- CONVOY (NCT06710626)
- Testing
- Assistive Robotic Arm
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Neuralink Corp
Osteoporosis, Spinal Cord Injuries
Treatment With Romosozumab Versus Denosumab to Improve Bone Mineral Density and Architecture in Subacute SCI
The objective of the proposed work is to determine whether administration for 12 months of romosozumab followed by 12 months of denosumab will maintain bone mass at the knee in subjects with subacute SCI compared to 24 months of…
- Trial name
- NCT05101018
- Testing
- Romosozumab, Denosumab
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Spinal Cord Injuries, Spinal Cord Diseases
Feasibility of HIIT in Spinal Cord Injury
Spinal cord injury (SCI) is debilitating to an individual's health, functional capacity and quality of life. This contributes to a sedentary lifestyle and an elevated risk for cardiometabolic and hypokinetic diseases.
- Trial name
- HIIT-SCI (NCT03152110)
- Testing
- HIIT
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Pittsburgh
Spinal Cord Injuries
Fitness Training Using WBEMS Among Individuals With SCI
Up to 15 individuals living with chronic SCI will be recruited for this study. Each participant will complete an initial clinical assessment before starting a 10-week training program.
- Trial name
- NCT04307017
- Testing
- StimaWell®EMS
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- University Health Network, Toronto
Spinal Cord Injuries, Healthy
Eccentric Muscle Training, Stimulation, and Biomarkers in SCI
The investigators are studying a new rehabilitation treatment for individuals trying to recover walking after spinal cord injury (SCI).
- Trial name
- NCT05337982
- Testing
- Downhill Eccentric Treadmill Training with Electrical Stimulation
- Where
- 2 sites in United States, Canada
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Spinal Cord Injuries, Incomplete
Protocol for Rapid Onset of Mobilization in Patients With Traumatic Spinal Cord Injury III (PROMPT-SCI III) Trial
This longitudinal cohort study will investigate the clinical benefits of early acute exercise therapy after mild spinal cord injury (SCI).
- Trial name
- PROMPT-SCI III (NCT07798310)
- Testing
- Cycling
- Where
- Canada
- Volunteers
- 107 people
- Sponsor
- Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Spinal Cord Injuries
TENS Trial to Prevent Neuropathic Pain in SCI
The purpose of this research study is to: 1) test whether transcutaneous electrical nerve stimulation (TENS) after spinal cord injury can reduce the onset of post-injury neuropathic pain; and 2) to learn more about this kind of…
- Trial name
- TENS (NCT03267810)
- Testing
- TENS
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Miami
Spinal Cord Injuries, Spastic Gait
Neuromodulation of Ankle Muscles in Persons With SCI
The ability to voluntarily move the ankles is important for walking. After spinal cord injury (SCI), this ability is impaired because of changes in the communication between the brain, spinal cord, and body.
- Conditions
- Spinal Cord Injuries, Spastic Gait, Foot Drop
- Trial name
- NCT04238013
- Testing
- Whole Body Vibration (WBV), Electrical Stimulation
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Shepherd Center, Atlanta GA
Spinal Cord Injury
Arm and Leg Cycling for Accelerated SCI Recovery
The purpose of this study is to examine interventions with paradigms involving upper and lower extremity cycling (A\&L cycling) with A\&L cycling with functional electrical stimulation (FES) (A\&L_FES group), A\&L cycling with…
- Trial name
- NCT06873776
- Testing
- A&L cycling, Body weight supported treadmill training (BWSTT)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Shirley Ryan AbilityLab
Neuropathic Pain
Intrathecal Baclofen (ITB) Bolus on Neuropathic Pain (NP). Preliminary Study.
Hypothesis: ITB bolus can have antinociceptive effect on neuropathic pain in spinal cord injury patients, which could depend on the subtype of pain, or on the lesion level, cervical or thoracic spinal cord injury.
- Trial name
- ITB (NCT02705950)
- Testing
- Intrathecal baclofen bolus
- Where
- Spain
- Volunteers
- 12 people
- Sponsor
- Institut Guttmann
Spinal Cord Injuries
Auricular Vagus Nerve Stimulation (aVNS) in Chronic Spinal Cord Injuries (SCI)
The purpose of this research is to test if Auricular Vagal Nerve Stimulation (aVNS) is safe in persons with spinal cord injury (SCI).
- Trial name
- NCT06588608
- Testing
- auricular nerve stimulation (aVNS)
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Miami
Spinal Cord Injuries, Skeletal Muscle Atrophy
Metabolic Health in Individuals With Spinal Cord Injury (SCI)
Individuals with spinal cord injury (SCI) live longer than before and live to an age where metabolic disorders become highly prevalent.
- Conditions
- Spinal Cord Injuries, Skeletal Muscle Atrophy, Metabolic Disease
- Trial name
- SCI (NCT03204240)
- Testing
- Neuromuscular electrical stimulation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Ohio State University
Spinal Cord Injuries
Cognitive Behavioural Therapy (CBT) For Improving Emotional Well Being in Spinal Cord Injuries (SCI)
The purpose of the study is to determine whether or not a brief psychological treatment called cognitive behaviour therapy will help people who have suffered a spinal cord injury to cope better with their current circumstances.
- Trial name
- CBT (NCT00861393)
- Testing
- CBT, Waitlist CBT
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Toronto Rehabilitation Institute