Clinical trials: Spinal Cord Injury, completed
Hernia Lumbar, Lumbar Canal Stenosis
Erector Spinae Plane Block in Lumbar Release Surgery
The aim of this study is to observe or not a reduction in the consumption of morphine within 72 hours of the realization of an erector spinae plane block when preparing for a non-instrumented spine surgery.
- Conditions
- Hernia Lumbar, Lumbar Canal Stenosis, Spinal Cord Compression
- Trial name
- MERLIBERTION (NCT04925882)
- Testing
- Erector spinae plane block
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Clinique Saint Jean, France
Acute Spinal Cord Injury
Early FES Cycling in Acute Spinal Cord Injury for Neuromuscular Preservation and Neurorecovery
Spinal cord injury (SCI) is a devastating condition that often leads to paralysis and multiple health problems such as muscle wasting, bone loss and spasticity.
- Trial name
- NCT05255679
- Testing
- Early FES, Delayed FES
- Where
- Canada
- Volunteers
- 35 people
- Sponsor
- University of Alberta
Spinal Cord Injuries, Pneumonia
Inspiratory Strength and Respiratory Complications After SCI Injury
The investigators conducting this study to investigate the relation between the respiratory muscle strength and respiratory complications.
- Trial name
- RESCOM (NCT02891096)
- Testing
- inspiratory muscle strength
- Where
- Switzerland
- Volunteers
- 550 people
- Sponsor
- Swiss Paraplegic Research, Nottwil
Spasticity in Spinal Cord Injured Persons
Randomized Double Blind Cross Over Study for Nabilone in Spasticity in Spinal Cord Injury Persons
Objectives: To determine whether nabilone, a synthetic cannabinoid, alleviates spasticity in people with spinal cord injury (SCI). Methods: Twelve subjects were enrolled in this double-blind, placebo-controlled, crossover study.
- Trial name
- NCT00623376
- Where
- Canada
- Sponsor
- University of Manitoba
Spinal Cord Injuries
Measuring the Neurological Benefits of Intermittent Hypoxia Therapy With MRI
This study uses Magnetic Resonance Imaging to image the brain and spinal cord before and after an Intermittent Hypoxia intervention.
- Trial name
- NCT05183113
- Testing
- Acute Intermittent Hypoxia
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Spinal Cord Injuries
Whole Body Exercise in Spinal Cord Injury: Effects on Psychosocial Function
Persons with spinal cord injury (SCI) are confronted with a multitude of psychological and physiological changes post-injury leading to seemingly insurmountable barriers to participating in daily life.
- Trial name
- NCT03411720
- Testing
- FES Row Training
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Spaulding Rehabilitation Hospital
Acute Spinal Cord Injury
Study to Evaluate the Safety and Pharmacokinetics of ALMB-0166 in Patients With Acute Spinal Cord Injury
The purpose of this study is to assess the safety, tolerability and pharmacokinetics of ALMB-0166 in patients with acute spinal cord injury.
- Trial name
- NCT05524103
- Testing
- ALMB-0166
- Where
- 2 sites in China
- Volunteers
- 24 people
- Sponsor
- AlaMab Therapeutics (Shanghai) Inc.
Spinal Cord Diseases, Spinal Cord Injuries
Long-term Paired Associative Stimulation as a Treatment for Incomplete Spinal Cord Injury of Non-traumatic Origin
The investigators have recently shown in incomplete SCI patients that long-term paired associative stimulation is capable of restoring voluntary control over some paralyzed muscles and enhancing motor output in the weak muscles…
- Trial name
- NCT03104803
- Testing
- long-term paired associative stimulation
- Where
- Finland
- Volunteers
- 5 people
- Sponsor
- Helsinki University Central Hospital
Spinal Cord Injury
Spinal Cord Injury - Assessing Tolerability and Use of Combined Rehabilitation and NeuroAiD
SATURN investigates the promising role of NeuroAiD in patients with spinal cord injury and will provide important information on the feasibility of conducting larger controlled trials.
- Trial name
- SATURN (NCT02537899)
- Testing
- NeuroAiD
- Where
- Malaysia
- Volunteers
- 30 people
- Sponsor
- Moleac Pte Ltd.
Spinal Cord Injury
Blood Pressure, Cerebral Blood Flow and Cognition in Spinal Cord Injury
Following spinal cord injury autonomic regulation of the cardiovascular system is impaired, which results in a variety of measurable abnormalities in blood pressure.
- Trial name
- NCT02307565
- Testing
- Midodrine
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Spinal Cord Injury
Gastrointestinal and Urinary Tract Microbiome After SCI
Changes in the GI microbiota and/or metabolomics have been linked to evolving transformations in immune system function and infection rates in experimental SCI in animal models.
- Trial name
- NCT02903472
- Where
- 6 sites in United States, Canada and 3 more
- Volunteers
- 43 people
- Sponsor
- University of British Columbia
Spinal Cord Injury, Tetraplegia
Effects of Exercise in People With Tetraplegia
This study is designed to assess the impact of exercise and supplementation on measures of fitness, function, and cardiovascular disease risk factors/modifiers in individuals with spinal cord injury (SCI).
- Trial name
- NCT01202019
- Testing
- Circuit Resistance Training (CRT)
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Miami
Spinal Cord Injury
Brain Machine Interface (BMI) in Subjects Living With Quadriplegia
In this study, investigators will show proof-of-concept that brain signals can be used in real-time, closed-loop mode to trigger stimulation for hand function.
- Trial name
- BMI (NCT02564419)
- Testing
- Medtronic Activa PC+S
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Jonathan Jagid
Bladder Outlet Obstruction, Multiple Sclerosis
GentleCath™ for Men Intermittent Catheter With FeelClean™ Technology
Male self catherterisng observational study.
- Conditions
- Bladder Outlet Obstruction, Multiple Sclerosis, Cauda Equina Syndrome, Enlarged Prostate With Lower Urinary Tract Symptoms
- Trial name
- NCT05470751
- Testing
- Intermittent self-catheterisation
- Where
- 16 sites in United States, France and 1 more
- Volunteers
- 72 people
- Sponsor
- ConvaTec Inc.
Chronic Spinal Cord Injury
The Up-LIFT Study of Non-Invasive ARC Therapy for Spinal Cord Injury
The Up-LIFT Study is a prospective, single-arm study designed to evaluate the safety and effectiveness of non-invasive electrical spinal cord stimulation (ARC Therapy) administered by the LIFT System to treat upper extremity…
- Trial name
- Up-LIFT (NCT04697472)
- Testing
- LIFT System
- Where
- 14 sites in United States, Canada and 2 more
- Volunteers
- 65 people
- Sponsor
- ONWARD Medical, Inc.
Cerebrovascular Disorder, Healthy
Magnetic Resonance Imaging Studies of Motor and Thought Processes
Magnetic resonance imaging (MRI) is a diagnostic tool that creates high quality images of the human body without the use of X-ray (radiation).
- Conditions
- Cerebrovascular Disorder, Healthy, Movement Disorder, Nervous System Disease
- Trial name
- NCT00001361
- Where
- United States
- Volunteers
- 610 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Spinal Cord Injuries
Determine the Association Between the Level of SCI With Chronic Respiratory Symptoms, Measures of Pulmonary Function, and Respiratory Illness.
This study is using a standardized method to assess respiratory function in SCI in order to determine the association between level of SCI with chronic respiratory symptoms, measures of pulmonary function, and respiratory…
- Trial name
- NCT00011336
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- US Department of Veterans Affairs
Spinal Cord Injuries
A Multi-Centre Clinical Study in Chronic Spinal Cord Injury Patients
To establish a solid foundation, e.g. network and a coordinating centre for testing new SCI therapies in forthcoming randomized controlled multi-centre clinical trials following international standards and guidelines
- Trial name
- NCT00592722
- Where
- 5 sites in China, Taiwan
- Volunteers
- 60 people
- Sponsor
- China Spinal Cord Injury Network
Spinal Cord Injuries
Lower-Limb Exoskeleton Technology for Non-Ambulatory Individuals With Spinal Cord Injury
The purpose of this study is to compare two types of wearable lower-extremity exoskeletons -a self-balancing device lower-extremity exoskeleton and a user-balancing device lower-extremity exoskeleton-to better understand their…
- Trial name
- NCT07128901
- Testing
- Ekso Indego Therapy, Wandercraft Atalante X
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Georgia Institute of Technology
Spinal Cord Injuries, Rehabilitation
Sprint Interval Training During Rehabilitation After Spinal Cord Injury
Immediately following a spinal cord injury (SCI), patients are admitted to inpatient rehabilitation where they undergo physical reconditioning in preparation for a return to home setting.
- Conditions
- Spinal Cord Injuries, Rehabilitation, Exercise
- Trial name
- SprintSCI (NCT03709095)
- Testing
- Sprint interval training, moderate intensity continuous training
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- McMaster University
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