Clinical trials: Spinal Cord Injury (SCI)
Neurogenic Bladder, Urinary Retention
Connected Catheter - Safety and Effectiveness Study
The Connected Catheter is a fully internal, urethral indwelling urinary prosthesis designed for improved bladder management in males with urinary retention disorders requiring catheterization.
- Conditions
- Neurogenic Bladder, Urinary Retention, Urologic Diseases
- Trial name
- NCT04059159
- Testing
- Connected Catheter
- Where
- 3 sites in United States
- Volunteers
- 8 people
- Sponsor
- Spinal Singularity
Spinal Cord Injury, Mental Health
A Feasibility Trial of an Enhanced Coping-oriented Supportive Programme for Community-dwelling People With Spinal Cord Injury
Spinal cord injury (SCI) is a neurological disorder that leads to "partial or complete loss of people's motor and/ or sensory function below the level of the injury".
- Conditions
- Spinal Cord Injury, Mental Health, Feasibility Studies, Acceptability Study
- Trial name
- NCT07170969
- Testing
- An Enhanced Coping-oriented Supportive Programme (E-COSP) for Community-Dwelling People with Spinal Cord Injury
- Where
- Hong Kong
- Volunteers
- 12 people
- Sponsor
- The Hong Kong Polytechnic University
Spinal Cord Injuries, Heart Diseases
Coronary Heart Disease as Measured by Coronary Calcium Score Among Individuals With Chronic Traumatic Spinal Cord Injury
This study includes male subjects age 45 to 70, who have sustained a traumatic Spinal Cord Injury (SCI) at least 10 years prior. Subjects will be interviewed for demographic data, including heart disease risk factors.
- Trial name
- NCT00628446
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Wake Forest University Health Sciences
Spinal Cord Injuries, Gut Microbiome
Impact of Gut Microbiome on Metabolic and Bowel Function During the First Year After Spinal Cord Injury
The Investigators will recruit 35 participants with acute SCI (within 6 weeks of injury) Fasting blood collection and bowel function survey will be conducted 3 times: at baseline [within 6 weeks of injury], 6, and 12 months after…
- Trial name
- NCT05670288
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Alabama at Birmingham
Spinal Cord Injuries
LTFU Study of Subjects With Cervical SCI Who Received AST-OPC1
This is a LTFU study for cervical SCI subjects that were administered AST-OPC1 cells in the main study AST-OPC1-01.
- Trial name
- NCT05975424
- Testing
- Magnetic Resonance Imaging (MRI)
- Where
- 6 sites in United States
- Volunteers
- 25 people
- Sponsor
- Lineage Cell Therapeutics, Inc.
Spinal Cord Injuries or Similar Neurological Weakness
EKSO Trial: Powered Exoskeleton for Ambulation in Subjects With Spinal Cord Injury (SCI)
This study seeks to test the safety and efficacy of the Esko device in SCI population and in populations with similar neurological weakness to the SCI population.
- Trial name
- EKSO (NCT01701388)
- Testing
- Ekso exoskeleton
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Shirley Ryan AbilityLab
Spinal Cord Injuries, Quality of Life
Exploring the Effect of Mindfulness on Quality of Life (QoL) in Spinal Cord Injury (SCI)
The purpose of this study is to determine if practicing mindfulness breathing exercises has an effect on the overall health of persons with SCI
- Trial name
- NCT06003712
- Testing
- Mindfulness
- Sponsor
- University of Miami
Spinal Cord Injuries (SCI)
Epidural Spinal Cord Stimulation for Restoring Walking in Spinal Cord Injury
The goal of this clinical trial is to evaluate the safety and effectiveness of Epidural Electrical Stimulation (EES) combined with rehabilitation training for the reconstruction of walking in patients with chronic spinal cord…
- Trial name
- NCT07306052
- Testing
- Epidural spinal cord stimulation, Rehabilitation Therapy, positron emission tomography-computed tomography (PET-CT)
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Spinal Cord Injuries, Pressure Injuries
Physical Therapy Wound Care Modalities in Patients With Spinal Cord Injury (SCI)
To examine the effects of Physical Therapist (PT) wound care modalities (pulsed wound irrigation (PWI) + electrical stimulation (ES), PWI only, and ES only) on wound healing in patients with spinal cord injuries (SCI).
- Trial name
- (SCI) (NCT05458947)
- Testing
- pulsed wound irrigation (PWI), electrical stimulation (ES), electrical stimulation (ES) and pulsed wound irrigation (PWI)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Wake Forest University Health Sciences
Paraplegia, Spinal Cord Injuries (SCI)
Safety and Performance Evaluation of ReWalk Reciprocating Gait Orthosis (RGO)
ReWalk suit developed by Argo Medical Technologies is designed to enable people with lower limb disabilities to carry out routine ambulatory functions (stand, walk etc.); it can be used by people with disabilities such as spinal…
- Trial name
- NCT01251549
- Testing
- ReWalk - a motorized exoskeleton suit
- Where
- 2 sites in United States, Italy
- Volunteers
- 32 people
- Sponsor
- ReWalk Robotics, Inc.
Spinal Cord Injury (SCI)
FLO2 for Recovery After SCI
Acute intermittent hypoxia (AIH) involves short (~1-2min) bouts of breathing low oxygen air to stimulate spinal neuroplasticity.
- Trial name
- NCT03833674
- Testing
- Daily AIH Block, Respiratory Strength Training Block, AIH + Strength Training Block
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of Florida
Spinal Cord Injury, Neurogenic Bladder (NB)
Coupled Gentamicin-Lactobacillus Rhamnosus in NLUTD
The main objective of the proposed research study is to determine in men and women with spinal cord injury/disease and neurogenic bladder whether the dose of coupled gentamicin \& Lactobacillus rhamnosus GG affects the…
- Conditions
- Spinal Cord Injury, Neurogenic Bladder (NB), Neurogenic Lower Urinary Tract Dysfunction, Multiple Sclerosis
- Trial name
- NCT07643974
- Testing
- Gentamicin, Lactobacillus Rhamnosus GG
- Where
- 2 sites in United States
- Volunteers
- 48 people
- Sponsor
- Medstar Health Research Institute
Neuropathic Pain
Intrathecal Baclofen (ITB) Bolus on Neuropathic Pain (NP). Preliminary Study.
Hypothesis: ITB bolus can have antinociceptive effect on neuropathic pain in spinal cord injury patients, which could depend on the subtype of pain, or on the lesion level, cervical or thoracic spinal cord injury.
- Trial name
- ITB (NCT02705950)
- Testing
- Intrathecal baclofen bolus
- Where
- Spain
- Volunteers
- 12 people
- Sponsor
- Institut Guttmann
Cervical Spinal Cord Injury, Tetraplegia
Testing the Decision Aid: Supporting Patient Decisions About Upper Extremity Surgery in Cervical SCI
Purpose: The objective of this study is to assess a newly created decision support intervention (DSI) or decision aid (DA) for people with spinal cord injury (SCI) to learn about and consider upper extremity reconstructive…
- Trial name
- NCT04995796
- Testing
- Surveys for Research Purposes
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Washington University School of Medicine
Spinal Cord Injuries
NeuroSuitUp: Neurorehabilitation Through Synergistic Man-machine Interfaces
NeuroSuitUp is a multidisciplinary neurophysiological \& neural rehabilitation engineering project, developed by the Lab of Medical Physics \& Digital Innovation, School of Medicine, Faculty of Health Science Aristotle University…
- Trial name
- NeuroSuitUp (NCT05465486)
- Testing
- Brain-Computer Interface control of robotic arms with augmented reality, Serious game with augmented reality
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Spinal Cord Injuries
Transcutaneous Tibial Nerve Stimulation for Spinal Cord Injury Neurogenic Bladder
The purpose of this study is to determine if electric stimulation to the leg, called transcutaneous tibial nerve stimulation (TTNS), can improve bladder outcomes in acute spinal cord injury.
- Trial name
- TTNS1yr (NCT04350359)
- Testing
- Variable-dose TTNS Protocol 5 x week, Fixed-dose TTNS Protocol, Variable-dose TTNS Protocol 2 x week
- Where
- 2 sites in United States
- Volunteers
- 111 people
- Sponsor
- The University of Texas Health Science Center, Houston
Spinal Cord Injury
Evaluation of a Specialized Yoga Program for Persons With Spinal Cord Injury (SCI)
The purpose of this randomized controlled study is to evaluate psychological variables, mindfulness, and pain in the context of a specialized yoga program for individuals with SCI.
- Trial name
- SCI (NCT02656927)
- Testing
- Yoga Condition
- Volunteers
- 22 people
- Sponsor
- University Health Network, Toronto
Spinal Cord Injuries
Lokomat® vs RoboGait® Under Different Guidance Force Settings in Motor-Incomplete SCI
This study compares two robotic-assisted gait training systems, Lokomat® and RoboGait®, used under different guidance force (GF) settings, in people with motor-incomplete spinal cord injury (iSCI).
- Trial name
- NCT07137780
- Testing
- Lokomat® V6 (GF < 90%), Lokomat® V6 (GF ≥ 90%), RoboGait®
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people
- Sponsor
- Ankara City Hospital Bilkent