Clinical trials: Spinal Cord Injury Thoracic
Spinal Cord Injury Cervical, Spinal Cord Injury Thoracic
A Study to Evaluate the Safety of a Delivery Device for Administering LCTOPC1 in Participants With Spinal Cord Injury
The DOSED clinical study evaluates the safety and utility of a novel delivery device to deliver LCTOPC1, a cell therapy, to the spinal cord of patients with a spinal cord injury (SCI).
- Conditions
- Spinal Cord Injury Cervical, Spinal Cord Injury Thoracic, Spinal Cord Injury, Acute, Spinal Cord Injury
- Trial name
- DOSED (NCT06841770)
- Testing
- OPC1
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Lineage Cell Therapeutics, Inc.
Thoracic Spinal Cord Injury
Safety of CRT100 on Treatment Spinal Cord Injury
The goal of this clinical trial is to test CRT100 treatment in participants with acute thoracic spinal cord injury. The main questions it aims to answer is safety of CRT100.
- Trial name
- CRT100 (NCT05739734)
- Testing
- CRT100
- Where
- 3 sites in Brazil
- Volunteers
- 5 people
- Sponsor
- Cristália Produtos Químicos Farmacêuticos Ltda.
Spinal Cord Injuries, Spinal Cord Diseases
Spinal Cord Stimulation to Restore Cough
The purpose of this trial is to determine the efficacy of spinal cord stimulation to produce an effective cough in patients with spinal cord injuries.
- Conditions
- Spinal Cord Injuries, Spinal Cord Diseases, Paralysis, Central Nervous System Diseases
- Trial name
- NCT00116337
- Testing
- Spinal Cord Stimulation to restore cough, Expiratory Muscle Stimulator
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- MetroHealth Medical Center
Spinal Cord Injuries
Extracorporeal Shockwave Therapy (ESWT) to Improve Function in Chronic ASIA-A Patients
The global prevalence of spinal cord injury is estimated between 236 to 4187/Million. A spontaneous recovery of the sense-motoric function is decreasing with the time after injury and is only seen sporadically after 1 to 2 years.
- Trial name
- NCT03399968
- Testing
- ESWT
- Where
- 2 sites in Austria
- Volunteers
- 25 people
- Sponsor
- AUVA Trauma Center Meidling
Spinal Cord Injury, Tetraplegia
Effect of Air-stacking on Peak Cough Flow in Patients With Acute Cervical or High Thoracic Spinal Cord Injury
Respiratory complications continue to be one of the leading causes of morbidity and mortality in people with spinal cord injury, especially among cervical and higher thoracic injuries.
- Trial name
- NCT01046175
- Testing
- Air-stacking with a manual resuscitator, Air-stacking with ventilator
- Where
- Norway
- Volunteers
- 10 people
- Sponsor
- Ullevaal University Hospital
Hypotension, Spinal Cord Injury
Effect of Tadalafil (Cialis) on the Cardiovascular System of Spinal Cord Injury (SCI) Males
To address the effect of tadalafil (Cialis) on the cardiovascular system of men with complete spinal cord injury at T-6 and above. The hypothesis is that tadalafil will cause significant hypotension in people with tetraplegia.
- Trial name
- NCT01067391
- Testing
- tadalafil
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Manitoba
Spinal Cord Injury
Long-Term Follow-Up of Transplanted Human Central Nervous System Stem Cells (HuCNS-SC) in Spinal Cord Trauma Subjects
The purpose of this study is to determine the long term safety and preliminary efficacy of intramedullary transplantation of HuCNS-SC cells in subjects with thoracic spinal cord trauma.
- Trial name
- NCT01725880
- Testing
- Observation
- Where
- Switzerland
- Volunteers
- 12 people
- Sponsor
- StemCells, Inc.
Spinal Cord Injury Thoracic
The Effect of Superimposed Electrical Stimulation on Sitting Balance, Respiratory Functions, and Abdominal Muscle Thickness in Complete Spinal Cord Injury
The primary aim of the current study was to investigate the effects of SiFES (superimposed functional electrical stimulation) on sitting balance in patients with complete Spinal Cord Injury (SCI) compared to exercise alone.
- Trial name
- NCT06104982
- Testing
- NeuroTrac MyoPlus Pro single-channel electromyography biofeedback electrotherapy devices, Isometric strengthening exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Ankara City Hospital Bilkent
Spinal Cord Injuries (SCI), Spinal Cord Injury, Chronic
BCI-Assisted SCS-EXS for Gait Optimization
The goal of this clinical trial is to evaluate the safety and technical feasibility of a novel brain-machine interface (BCI)-assisted spinal cord stimulation (SCS) and exoskeleton (EXS) system in patients with spinal cord injury…
- Conditions
- Spinal Cord Injuries (SCI), Spinal Cord Injury, Chronic, Spinal Cord Injury, Spinal Cord Injury Cervical
- Trial name
- BASEGO (NCT06939660)
- Testing
- BCI-SCS-EXS
- Where
- China
- Volunteers
- 3 people
- Sponsor
- Xuanwu Hospital, Beijing
Traumatic Thoracic Acute Spinal Cord Injury
The INSPIRE Study: Probable Benefit of the Neuro-Spinal Scaffold for Treatment of AIS A Thoracic Acute Spinal Cord Injury
This is an HDE probable benefit, open-label, non- randomized, single-arm, multicenter study to evaluate the safety and probable benefit of the poly(lactic-co-glycolic acid)-b-poly(L-lysine) Scaffold ("Scaffold") in subjects with…
- Trial name
- NCT02138110
- Testing
- Neuro-Spinal Scaffold
- Where
- 8 sites in United States
- Volunteers
- 20 people
- Sponsor
- InVivo Therapeutics
Spinal Tumor, Traumatic Injury of Spine
Study to Evaluate the Safety and Clinical Outcome of Using Navigation System in Pedicle Screw Placement in Spine Surgery
The research project is testing whether in screw insertion of spine surgery using "Anatase" Spine Surgery Navigation System is at least as safe and accurate as using O-arm assisted spine surgery- Medtronic Stealthstation S7…
- Conditions
- Spinal Tumor, Traumatic Injury of Spine, Degenerative Spine Disease
- Trial name
- NCT04578691
- Testing
- "Anatase" Spine Surgery Navigation System, Medtronic Stealthstation S7 Treatment Guidance System
- Where
- Taiwan
- Volunteers
- 55 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Rheumatoid Arthritis, Ankylosing Spondylitis
PatientSpot Formerly Known as ArthritisPower
Patient Power is a patient research network and database (registry) to collect prospective information about demographics, self-reported diagnoses and medications, and willingness to participate in research from participants with…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout
- Trial name
- NCT03840928
- Where
- United States
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Global Healthy Living Foundation
Spinal Cord Injuries, Spinal Cord Injury
Neuromodulation to Reduce Muscle Stiffness Following Spinal Cord Injury
People with spinal cord injuries may experience muscle tightness or uncontrollable spasms. This study is being conducted to investigate whether transcutaneous spinal stimulation can improve these symptoms.
- Conditions
- Spinal Cord Injuries, Spinal Cord Injury, Spinal Cord Injury Cervical, Spinal Cord Injury Thoracic
- Trial name
- NCT06274021
- Testing
- Transcutaneous spinal stimulation at 100 Hz, Transcutaneous spinal stimulation at 50 Hz, Transcutaneous spinal stimulation at 50 Hz and single dose of baclofen
- Where
- 2 sites in United States
- Volunteers
- 16 people
- Sponsor
- University of Mississippi Medical Center