Clinical trials: Spinal Decompression
Lumbar Disc Herniation, Lumbar Radiculopathy
PLDD With or Without Transforaminal Epidural Steroid Injection in Lumbar Disc Herniation
This prospective observational study aims to evaluate the clinical outcomes of patients with single-level lumbar disc herniation who undergo routine percutaneous laser disc decompression (PLDD).
- Trial name
- PLDD-TFESI (NCT07400068)
- Testing
- Percutaneous Laser Disc Decompression (PLDD), Transforaminal Anterior Epidural Steroid Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Mersin University
Spinal Decompression, Analgesia
Erector Spinae Block Vs Ketamine-based Multimodal Analgesia Protocol in Lumber Decompressive Surgery
The aim of this study is to compare the quality of recovery of the erector spinae plane block (ESPB) versus ketamine-based multimodal analgesia regimen after spine decompressive surgery.
- Conditions
- Spinal Decompression, Analgesia, Erector Spinae Plane Block, Ketamine
- Trial name
- NCT07001605
- Testing
- ketamine, Erector Spinae Plane Block, Wound infiltration
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Kasr El Aini Hospital
Tendinopathy, Shoulder Impingement Syndrome
The Effect of an Evidence-based Physiotherapy Regimen for Patients With Rotator Cuff Tendinopathy
Primary aim of this study is to investigate wether an evidence-based physiotherapy regimen is more effective than standard care in patients referred for arthroscopic surgery of the shoulder.
- Conditions
- Tendinopathy, Shoulder Impingement Syndrome, Shoulder Pain, Subacromial Impingement
- Trial name
- NCT02304003
- Testing
- Structured Physiotherapy Regimen, Standard Care
- Where
- Norway
- Volunteers
- 80 people
- Sponsor
- Bergen University College
Pain, Spine Fusion
Randomized Controlled Comparison of Pre-op TLIP vs Intra-op TLIP
Single-center, randomized study will enroll 50 subjects who are scheduled for 1-3 level posterior laminectomy \& fusion. Study participants who are eligible for the posterior lumbar laminectomy and fusion procedure will be…
- Trial name
- NCT06154980
- Testing
- Preoperative Ultrasound TLIP, Intraoperative TLIP
- Where
- United States
- Sponsor
- Corewell Health East
Herniated Disc
Radiofrequency Nucleoplasty vs Percutaneous Nucleotomy vs Decompression Catheter in Lumbar Disc Herniation
The purpose of this study is to learn which of three minimally invasive procedures is the most effective for treatment of contained lumbar disc herniation.
- Trial name
- NCT00300898
- Testing
- Nucleoplasty, Percutaneous decompression, Intervertebral electrothermal disc decompression (IDET)
- Sponsor
- The Cleveland Clinic
Sacral Fractures, Traumatic Unstable Sacral Fractures
Open Versus Minimally Invasive Fixation for Unstable Sacral Fractures in Adults
Severe injuries to the lower spine and pelvis, known as traumatic unstable sacral fractures, are complex injuries that often require surgery to stabilize the bones and prevent long-term disability.
- Conditions
- Sacral Fractures, Traumatic Unstable Sacral Fractures, Spinopelvic Dissociation, Pelvic Ring Injuries
- Trial name
- NCT07534579
- Volunteers
- 60 people
- Sponsor
- Assiut University
Lumbar Spinal Stenosis
Decompressive Laminectomy Versus Laminectomy With Transpedicular Fixation in Lumbar Spinal Stenosis
Lumbar spinal stenosis is a condition where the spinal canal becomes narrowed and can cause symptoms such as back pain, numbness, leg pain, and difficulty walking.
- Trial name
- NCT07281625
- Testing
- Decompressive Laminectomy, Decompressive Laminectomy With Transpedicular Screw Fixation
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Punjab Health Care Commission
Cervical Stenosis, Degenerative Cervical Spinal Stenosis
Laminoplasty Versus Laminectomy With Lateral Mass Fixation in Management of Degenerative Cervical Canal Stenosis
Cervical canal stenosis (CCS) is a condition characterized by the narrowing of the spinal canal in the cervical spine, leading to compression of the spinal cord and nerve roots.
- Trial name
- NCT07177651
- Testing
- Laminoplasty, Laminectomy with lateral mass fixation
- Volunteers
- 2 people
- Sponsor
- Assiut University
Spine Surgery
Safety of Tranexamic Acid in Reducing Bleeding in Adults Undergoing Spinal Surgery
Spinal fusion surgery can be associated with significant blood loss requiring allogeneic blood transfusion. Tranexamic acid is a synthetic amino acid with antifibrinolytic action that has been shown to reduce perioperative blood…
- Trial name
- NCT00444470
- Testing
- Tranexamic acid
- Where
- 3 sites in Canada
- Volunteers
- 151 people
- Sponsor
- University Health Network, Toronto
Tumor of Spinal Cord
Establishment and Application of Early Postoperative Activity Plan for Patients After Hemi-laminectomy for Lumbar Spinal Tumor Resection
Objective to construct the related early activity program for patients with lumbar intraspinal tumor after hemilaminectomy, and evaluate the postoperative limb function exercise according to the content of the program.
- Trial name
- NCT04968730
- Testing
- Postoperative rehabilitation nursing
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Metastatic Cancer, Metastatic Lung Cancer
Definitive Radiation for High-Risk Spine Metastases
This study is looking at whether patients with cancer that has aggressively spread to the spine can be treated with stereotactic body radiation therapy only and avoid a large spine surgery
- Conditions
- Metastatic Cancer, Metastatic Lung Cancer, Metastatic Breast Cancer, Metastatic Tumor
- Trial name
- NCT06165419
- Testing
- SBRT to the spine
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Stony Brook University
Degenerative Lumbar Spinal Stenosis
Biportal Endoscopy Spine Surgery (BESS )Versus Unilateral Laminotomy Bilateral Decompression (ULBD ): RCT, Non-inferiority Trial
This study is to compare the clinical outcome between the biportal endoscopic decompression and the unilateral approach bilateral decompression in spinal stenosis
- Trial name
- NCT03302507
- Testing
- BESS, ULBD
- Where
- South Korea
- Volunteers
- 64 people
- Sponsor
- Seoul National University Hospital
Failed Back Surgery Syndrome, Post-laminectomy Syndrome
Subcutaneous Nerve Stimulation for Failed Back Surgery Syndrome (FBSS) Patients
The purpose of this study is to assess the safety and efficacy of Subcutaneous Nerve Stimulation (SQS) (also known as Peripheral Nerve Stimulation [PNS]) in the reduction of chronic, intractable post-surgical back pain in adults.
- Trial name
- SubQStim (NCT01818297)
- Testing
- PrimeAdvanced® neurostimulator system
- Where
- 27 sites in United States
- Volunteers
- 137 people
- Sponsor
- MedtronicNeuro
Spine Surgery, Telerehabilitation
Telerehabilitation After Spine Surgery
The goal of this randomized clinical trial is to assess how different methods of delivering post-operative instructions affect the participants' recovery after spinal decompression surgery.
- Conditions
- Spine Surgery, Telerehabilitation, Low Back Pain
- Trial name
- NCT07795697
- Testing
- Telerehabilitation method, Nurse instructions, Physiotherapy after surgery, personal
- Where
- Finland
- Volunteers
- 300 people
- Sponsor
- Kuopio University Hospital
Lumbar Disc Herniation, Spinal Disk Injury
Decompression With ELDOA on Lumbar Disc Protrusion Patient
Decompression therapy is a result-oriented approach but it expensive and minimum availability in Pakistan. In physical therapy, we use different exercises to solve multiple spine problems.
- Conditions
- Lumbar Disc Herniation, Spinal Disk Injury, Protrusion
- Trial name
- NCT04760210
- Testing
- Control Group, Decompression Group, ELDOA
- Where
- Pakistan
- Volunteers
- 180 people
- Sponsor
- Aqua Medical Services (Pvt) Ltd
Spinal Cord Compression, Neoplasm Metastasis
Stereotactic Radiosurgery in Metastatic Spinal Cord Compression
To determine whether stereotactic radiosurgery of metastatic spinal cord compression is equivalent to decompressive surgery followed by external body radiation therapy to maintain ability to walk at 6 weeks.
- Trial name
- Stereocord (NCT02167633)
- Testing
- Decompression surgery, Radiosurgery, Fractionated Radiotherapy
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Lumbar Decompression
Ambulatory Geriatric Endoscopic Spine
The research focuses on evaluating the clinical outcomes of endoscopic lumbar decompression surgery performed in an outpatient setting for patients over 75 years old.
- Trial name
- AGES (NCT06523426)
- Testing
- Patient treated by spinal endoscopy
- Where
- 4 sites in France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Bordeaux
Transcutaneous Electrical Acupoint Stimulation, Hemifacial Spasm
Transcutaneous Electrical Acupoint Stimulation on Postoperative Dizziness in Hemifacial Spasm Patients
To observe the prevention and treatment effect of transcutaneous electrical acupoint stimulation (TEAS) on postoperative dizziness in patients with hemifacial spasm undergoing microvascular decompression surgery, and its possible…
- Conditions
- Transcutaneous Electrical Acupoint Stimulation, Hemifacial Spasm, Dizziness
- Trial name
- NCT04621578
- Testing
- HANS 100B stimulator (4 conductors, 8 electrodes; Jisheng Co., Nanjing, China)
- Where
- China
- Volunteers
- 86 people
- Sponsor
- Peking University People's Hospital
Trigeminal Neuralgia, Microvascular Decompression Surgery
Post-Operative Trigeminal Pain After Microvascular Decompression for Trigeminal Neuralgia
The goal of this observational study is to learn about the long-term effects of microvascular decompression (MVD) in patients with trigeminal neuralgia (TN).
- Conditions
- Trigeminal Neuralgia, Microvascular Decompression Surgery, Post-operative Pain
- Trial name
- NCT07216547
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Rutgers, The State University of New Jersey
Arnold-Chiari Malformation, Type 1, Chiari Malformation Type I
Posterior Fossa Decompression With or Without Duraplasty for Chiari Type I Malformation With Syringomyelia
The purpose of this study is to determine whether a posterior fossa decompression or a posterior fossa decompression with duraplasty results in better patient outcomes with fewer complications and improved quality of life in…
- Conditions
- Arnold-Chiari Malformation, Type 1, Chiari Malformation Type I, Type I Arnold-Chiari Malformation, Syringomyelia
- Trial name
- NCT02669836
- Testing
- Posterior fossa decompression, Dural Augmentation
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- Washington University School of Medicine