Clinical trials: Spinal Hypotension
Post Spinal Hypotension
Perfusion Index vs Positional Hemodynamic Changes to Predict Hypotension After Spinal Anaesthesia in Caesarean Section
Comparative Study between the Perfusion Index and Positional Haemodynamic Changes for Prediction of Hypotension after Spinal Anaesthesia in Caesarean Section
- Trial name
- NCT05587153
- Testing
- perfusion index in all parturient recruited for the study
- Where
- 2 sites in Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Hypotension
Can Passive Leg Raise Prevent Spinal Anesthesia-induced Hypotension During Cesarean Section?
All over the world, spinal anesthesia is widely used in cesarean sections due to its superiority over general anesthesia. Due to reasons such as increased sensitivity to local anesthetics and increased intra-abdominal pressure in…
- Trial name
- NCT04673253
- Testing
- Passive leg Raise, control
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Antalya Training and Research Hospital
CerebroSpinal Fluid (CSF) Leak
The Freiburg Registry on SpontanEous IntercrAnial Hypotension (SIH) & Post-duraL Puncture Headache (PDPH)
Spinal CSF leaks are considered as rare disease. They cause a variety of symptoms, mainly culminating in a chronic headache syndrome. Crucially, yet often disregarded, the disease holds the potential for cure.
- Trial name
- SEAL (NCT06711731)
- Where
- Germany
- Volunteers
- 2,000 people
- Sponsor
- University Hospital Freiburg
Spinal Anesthesia Induced Hypotension
COMPARISON BETWEEN EFFICACY OF NOREPINEPHRINE AND PHENYLEPHRINE BOLUSES for PREVENTION OF SPINAL ANAESTHESIA INDUCED HYPOTENSION IN OBSTETRICAL PATIENTS UNDERGOING EMERGENCY CESAREAN SECTION-A Double Blind Randomized Controlled Trial
The goal of this clinical trial is to learn if norepinephrine is more effective than phenylephrine for prevention of spinal anesthesia induced hypotension.
- Trial name
- NCT06836986
- Testing
- Norepinephrine Bolus, Phenylephrine bolus
- Where
- Pakistan
- Volunteers
- 124 people
- Sponsor
- Dow University of Health Sciences
Hypotension
Dexamethasone Blunts the Hypotensive Effect of Spinal Anesthesia in Geriatric Patients Undergoing Lower Limb Orthopedic Surgeries
Based on the data that DEX increases the TPR and may decrease the expression of serotonin the investigator conducted this study to test the hypothesis that the prophylactic intravenous infusion (IVI) of DEX can attenuate the…
- Trial name
- NCT03664037
- Testing
- Dexamethasone phosphate
- Where
- Egypt
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Spinal Cord Injuries, Multiple System Atrophy, Parkinson Variant
Transcutaneous Spinal Cord Stimulation Home Study
The goal of this pilot clinical trial is to examine the safety and feasibility of SCONE as home based therapy for orthostatic hypotension and bowel dysfunction in individuals with spinal cord injury or multiple system atrophy.
- Trial name
- NCT06838637
- Testing
- Spinal COrd NEuromodulation ("SCONE") Device
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- Michael Berger
Hypotension
Investigating Maternal Effects of Positions Applied in Patients Preparing for Caesarean Section Under Spinal Anesthesia
After the approval of the Ethics Committee, 120 patients were planned to be included in the study between 15.06.2022 and 15.01.2023.
- Trial name
- cs position (NCT05595928)
- Testing
- position
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people
- Sponsor
- Aydin Maternity and Child Health Hospital
Spinal Cord Injuries
Diet and Exercise Solutions to Postprandial Hypotension
The purpose of this study is to determine if a low glycemic diet and lower-body electrical stimulation can reduce postprandial hypotension in individuals with chronic spinal cord injury.
- Trial name
- NCT06882460
- Testing
- Low glycemic load, Electrical stimulation exercise, High glycemic load diet
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Ohio State University
Cesarean Section, Cardiac Output
Best Regimen for Phenylephrine Administration During Cesarean Section
During Cesarean delivery, phenylephrine is used to maintain the patient's blood pressure. Low blood pressure is the most common side effect of the spinal medication used to anesthetize the patient prior to the start of surgery.
- Conditions
- Cesarean Section, Cardiac Output, Hypotension
- Trial name
- NCT00996190
- Testing
- Phenylephrine
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Orthostatic Hypotension, Postural Hypotension
Transcranial Electrical Stimulation for Management of Orthostatic Instability in Acute Cervical Spinal Cord Injury
Individuals with acute cervical spinal cord injury (SCI) can suffer from an excessive and prolonged fall in blood pressure when assuming an upright position, such as transitioning from lying to sitting or standing, a condition…
- Trial name
- NCT01874782
- Testing
- transcranial electrical stimulation
- Where
- Canada
- Volunteers
- 4 people
- Sponsor
- University of British Columbia
Pregnancy Related, Cesarean Section Complications
Predictive Hemodynamic Monitoring During Elective Cesarean Section
Single shot spinal anesthesia (SA) is the most commonly used technique for Caesarean section (CS) . SA is associated with maternal hypotension (Post Spinal Hypotension - PSH) often accompanied by nausea, vomiting, bradycardia and…
- Conditions
- Pregnancy Related, Cesarean Section Complications, Hypotension on Induction, Anesthesia Complication
- Trial name
- PREDICTION (NCT06729827)
- Testing
- Hypotension prediction Index - HPI
- Where
- Italy
- Volunteers
- 102 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Spinal Anesthesia-induced Hypotension
Preoperative Ultrasonographic Evaluation of the Right Common Femoral Vein Diameter for Predicting Spinal Anesthesia-induced Hypotension in Elderly Patients
In this study we will determine the ability of preoperative ultrasonographic evaluation of the right common femoral vein diameter to predict spinal anesthesia-induced hypotension in elderly patients.
- Trial name
- NCT05342311
- Testing
- preoperative ultrasonographic evaluation of right common femoral vein diameter
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Cairo University
Intracranial Hypotension
Postoperative Changes in Optic Nerve Sheath Diameter in Patients Undergoing Spinal Anesthesia for Cesarean Delivery
This is observational study. The investigator will measure optic nerve sheath diameter by ultrasound on the eye after cesarean section under spinal anesthesia.
- Trial name
- NCT04301830
- Volunteers
- 50 people
- Sponsor
- SMG-SNU Boramae Medical Center
Hypotension
Colloid Preload Versus Crystalloid Co-load in Cesarean Section Under Spinal Anesthesia
Comparison between colloid preload and crystalloid co-load in cesarean section under spinal anesthesia. 1. The primary outcome was the incidence of hypotension 2.
- Trial name
- CPvsCC (NCT03107598)
- Testing
- colloid preload
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- University Hospital, Mahdia
Anxiety, Hypotension
Impact of Music on Satisfaction, Anxiety, and Hemodynamics During Spinal Anesthesia for Cesarean Delivery
The aim of this study is to evaluate the effect of perioperative music on maternal anxiety, hemodynamic response to spinal anesthesia, postoperative pain medication requirement, and overall maternal satisfaction.
- Trial name
- NCT02732964
- Testing
- Pandora Music, Mozart Music
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Cesarean Section
Fluid Volume-hypotension Association in Cesarean Under Neuraxial Anesthesia
Hypotension resulted from neuraxial block is a common problem, of which is a special issue in patients undergoing Cesarean section.
- Trial name
- VOHOCUNA (NCT01013090)
- Testing
- Ringer's Lactate, Six percent hydroxyethyl starch
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Nanjing Medical University
Post Spinal Hypotension
Can Subclavian / Infraclavicular Axillary Vein Collapsibility Index Predict Post-Spinal Hypotension in Caesarean Section Operations?
Postspinal hypotension (PSH) is a common side effect with an incidence of 15.3% to 33%, which may result in organ hypoperfusion and ischemic events (1,2).
- Trial name
- Cesarean (NCT05120258)
- Volunteers
- 100 people
- Sponsor
- Selcuk University
Planned Cesarean Section
Acute Preoperative Stress and Hypotension After Spinal Anesthesia. SAS for "Salivary Amylase and Stress "
Spinal anesthesia is the technique of choice for planned cesarean section. It is associated with a high frequency of maternal hypotension.
- Trial name
- SAS (NCT01862055)
- Where
- France
- Volunteers
- 79 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Postspinal Hypotension, Pregnant Women Undergoing Cesarean Delivery
Carotid Flow Measurements in Pregnant Women
The goal of this observational study is to reveal the relation between carotid flow changes and post-spinal hypotension in pregnant women between the ages of 20-40.
- Trial name
- NCT06813989
- Testing
- carotid ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Haseki Training and Research Hospital
Hypotension Drug-Induced, Spinal Aneshtesia
Effect of Lateral Decubitus Position After Spinal Anesthesia on Hemodynamic Stability in High-Risk Geriatric Patients
Spinal anesthesia is a common and preferred anesthetic technique for lower extremity orthopedic surgery in elderly patients. However, it can cause a significant drop in blood pressure (hypotension), especially in high-risk older…
- Conditions
- Hypotension Drug-Induced, Spinal Aneshtesia, Geriatric, Orthopedic Surgery Patients
- Trial name
- NCT07597148
- Testing
- Lateral Decubitus Positioning, Immediate Supine Positioning
- Volunteers
- 70 people
- Sponsor
- University of Health Sciences Balikesir Hospital Eduation and Research