Clinical trials: Spinal Injury
Spinal Cord Injuries
Spinal Cord Injury Program in Exercise
The purpose of this study is to examine two 8-week, remotely delivered exercise interventions: Movement-to-Music (M2M) and Standard Exercise Training (SET), with 327 adults with spinal cord injury.
- Trial name
- SCIPE (NCT03925077)
- Testing
- Movement-to-Music, Standard Exercise Training
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- University of Alabama at Birmingham
Spinal Cord Injury
Rehabilitation Program for Bladder Control in Individuals With Incomplete Spinal Cord Injury
This prospective, randomized, double-blind clinical trial (with both participants and outcome assessors blinded to group assignments) was carried out at the outpatient clinic of the Faculty of Physical Therapy, Cairo University…
- Trial name
- BCSCI (NCT07008157)
- Testing
- 1. IFC, 2. Timed voiding., motor imagery training
- Where
- Egypt
- Volunteers
- 74 people
- Sponsor
- Cairo University
Urinary Tract Infections
Prevention of Urinary Tract Infection (UTI) in Persons With Spinal Cord Injury (SCI)
Urinary tract infection (UTI) is the most common infection in patients with spinal cord injury (SCI) and is linked to major undesired results or complications including death.
- Trial name
- NCT00309114
- Testing
- bacterial interference
- Where
- 5 sites in United States
- Volunteers
- 65 people
- Sponsor
- Baylor College of Medicine
Spinal Cord Injuries, Neuropathic Pain
Virtual Walking Intervention for Neuropathic Pain in Spinal Cord Injury
The purpose of this study is to determine if playing a virtual reality walking game can help improve neuropathic pain in adults with chronic spinal cord injury.
- Trial name
- VRWalk (NCT05005026)
- Testing
- VR Game 1, VR Game 2
- Where
- 3 sites in United States, Australia
- Volunteers
- 250 people
- Sponsor
- Texas A&M University
Spinal Cord Injury, Chronic Spinal Cord Injury
First-in-Human Clinical Trial of STUP-001, an In Vivo Direct Cell Conversion Gene Therapy for AIS-A/B Chronic Spinal Cord Injury
This study aim to investigate the safety and exploratory efficacy of STUP-001 which is AAV-based spinal cord injury investigational product.
- Trial name
- STUP-001 (NCT06922890)
- Testing
- STUP-001
- Where
- South Korea
- Volunteers
- 9 people
- Sponsor
- Yonsei University
Spinal Cord Injury
Hypothermia Following Acute Spinal Cord Injury
The purpose of this study is to investigate the long term outcome of patients who receive hypothermia treatment for spinal cord injury.
- Trial name
- NCT01739010
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of Miami
Spinal Cord Injury
The Effect of an Exercise Program on Physical Function After a Spinal Cord Injury
This study would focus on adding a group exercise program to the usual therapy delivered in the hospital. We propose to design an exercise program that would be 30 minutes in length, 3 times per week.
- Trial name
- NCT00535210
- Testing
- Cardiovascular training, Balance training
- Where
- Canada
- Volunteers
- 9 people
- Sponsor
- University of British Columbia
Hip Fractures
Comparative Study to Evaluate the Efficacy of Ultrasound-Guided Pericapsular Nerve Group (PENG) Block Versus Fascia Iliaca Compartment (FIC) Block on the Postoperative Analgesic Effect in Patients Undergoing Hip Surgeries Under Spinal Anesthesia.
Fractures in and around the hip are quite common irrespective of both the young and elderly population groups and are associated with extreme pain.
- Trial name
- NCT05751291
- Testing
- Bupivacaine Hydrochloride
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Sohag University
Spinal Cord Injuries, Myofascial Pain Syndrome
Effectiveness of Dry Needling as a Treatment of Shoulder Myofascial Pain Syndrome in Spinal Cord Injury Patients
Shoulder pain in people with spinal cord injury is one of the most prevalent in acute and chronic patients because of weakness in shoulder periarticular muscles, and also because of overuse of these part of the body in assistive…
- Conditions
- Spinal Cord Injuries, Myofascial Pain Syndrome, Shoulder Pain, Puncture
- Trial name
- NCT03709797
- Testing
- Dry needling in infraspinatus muscle
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad de León
Healthy Control, Spinal Cord Injury
Paired Stimulation Plasticity for Motor Recovery in Humans With and Without Spinal Cord Injury
This study will investigate how aging and spinal cord injury (SCI) affect the transmission and plasticity of the corticospinal and reticulospinal tracts, which are important pathways for motor control.
- Trial name
- NCT07814313
- Testing
- CST PAS, RST PAS
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Aortic Stenosis
The Effects of High Spinal Anesthesia on Heart Function, Stress Response and Pain Control in Aortic Valve Surgery
This study is looking at the effects of high spinal anesthesia (also known as total spinal anesthesia) combined with general anesthesia versus general anesthesia alone on the following: Stress response: Patients undergoing aortic…
- Trial name
- NCT00348920
- Testing
- High Spinal and General Anesthesia
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- University of Manitoba
Infertility, Male
Improvement of Reproductive Function in Men With Spinal Cord Injury (SCI)
This is a study of infertility which often occurs in men with spinal cord injury. Most men with spinal cord injury have a normal sperm count but abnormally low sperm motility - which means that the sperm does not swim well.
- Trial name
- NCT05903859
- Testing
- Probenecid 500 Milligrams (mg), probenecid 250 Milligrams (mg)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Miami
Spinal Cord Injury, Stroke
Control of Unsupported Paraplegic Standing
The study will investigate the feasibility of using functional electrical stimulation (FES) of the calf muscles of paraplegic subjects to assist in posture stabilisation during standing.
- Trial name
- NCT00204113
- Testing
- Multi-purpose rehabilitation frame, Surface Functional Electrical Stimulation
- Where
- 2 sites in United Kingdom
- Volunteers
- 10 people
- Sponsor
- University of Glasgow
Spinal Cord Injury
Lithium, Cord Blood Cells and the Combination in the Treatment of Acute & Sub-acute Spinal Cord Injury
The trial is to investigate the safety and efficacy of oral lithium, intraspinal umbilical cord blood mononuclear cell transplant, and the combination in the treatment of acute and subacute spinal cord injury
- Trial name
- NCT01471613
- Testing
- Conventional Treatment, Lithium Carbonate Tablet, Cord Blood Cell
- Where
- China
- Volunteers
- 16 people
- Sponsor
- China Spinal Cord Injury Network
Spinal Cord Injuries, Urinary Bladder, Neurogenic
Cystometry Using a Novel Microsensor System in Patients With Neurogenic Bladder Dysfunction
The aim of this study is to assess the feasibility and safety of a novel system for percutaneous measurement of bladder pressure.
- Trial name
- PEPRE2 (NCT06445426)
- Testing
- Cystometry
- Where
- Norway
- Volunteers
- 33 people
- Sponsor
- Sunnaas Rehabilitation Hospital
Spinal Cord Injury, Muscle Spasticity
Safety and Efficacy of Oral Fampridine-Sustained Release (SR) for the Treatment of Spasticity Resulting From Spinal Cord Injury
Normally, nerve fibers carry electrical impulses through the spinal cord, providing communication between the brain and the arms and legs.
- Trial name
- NCT01683838
- Testing
- Fampridine-SR
- Where
- 30 sites in United States, Canada
- Volunteers
- 204 people
- Sponsor
- Acorda Therapeutics
Vertebral Fracture, Balance
Evaluation of Balance and Gait Weight Distribution in Patients With Vertebral Column Fractures
Vertebral column fracture presents a significant warning of subsequent osteoporotic fracture and frequent falls. The presence of an osteoporotic vertebral fracture is also a predictor of further risk of vertebral and other…
- Conditions
- Vertebral Fracture, Balance, Gait, Unsteady
- Trial name
- NCT05010135
- Testing
- Zebris Gait System assessment for gait weight distribution + EMG evaluation of Quadriceps, Hamstrings, Tib Anterior and Calves + Positional Sense assessment
- Where
- Hong Kong
- Volunteers
- 80 people
- Sponsor
- Tung Wah College
Spinal Cord Injuries, Spina Bifida
Examining Capacity Building of Youth With Physical Disabilities to Pursue Participation Following the PREP Intervention.
The goal of this clinical trial is to learn about how a participation-based intervention builds capacity of youth with physical disabilities to pursue activities of their choice in the community.
- Conditions
- Spinal Cord Injuries, Spina Bifida, Musculoskeletal Disorder, Juvenile Arthritis
- Trial name
- NCT06007885
- Testing
- Pathways and Resources to Engagement and Participation (PREP)
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- McGill University
Osteoporotic Fractures, Vertebral Fracture
Percutaneous Vertebroplasty Vs. Sham for Osteoporotic Vertebral Compression Fractures Focusing on Pain and Economy.
The purpose of this randomized double-blind clinical trial is to determine the efficacy of percutaneous vertebroplasty (PVP) in relieving severe pain in patients with MRI-verified acute or sub-acute osteoporotic vertebral…
- Trial name
- VOPE2 (NCT06141187)
- Testing
- Vertebroplasty
- Where
- Denmark
- Volunteers
- 240 people
- Sponsor
- Spine Centre of Southern Denmark
Spinal Cord Injury
Coronary Artery Calcification Score and Risk Factors for Coronary Artery Disease in Persons With Spinal Cord Injury
Although conventional risk factors for coronary heart disease (CHD) have been identified and routinely used to determine risk for CHD in the general population, a systematic approach to determine population-specific risk for CHD…
- Trial name
- CAC (NCT02007226)
- Where
- 2 sites in United States
- Volunteers
- 83 people
- Sponsor
- James J. Peters Veterans Affairs Medical Center