Clinical trials: Spinal Manipulation, active
Scoliosis
Biomechanical Study of Lever Positioning Manipulation on Scoliosis
Research background Scoliosis is a common three-dimensional spinal deformity, especially in adolescents. In severe cases, it can lead to thoracic deformation and cardiopulmonary dysfunction.
- Trial name
- NCT07325045
- Testing
- Lever positioning manipulation
- Where
- China
- Volunteers
- 30 people
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Stroke
Lumbar Spinal Manipulation in Stroke
The aim of the study is to investigate the effects of lumbar spinal manipulation on balance and fall risk of the patients with chronic stroke.
- Trial name
- NCT07619586
- Testing
- Lumbar Spinal Manipulation
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Bitlis Eren University
Osteopathic Manipulative Treatment (OMT) Effects on Cerebrospinal Fluid (CSF) Dynamics
Exploring How Osteopathic Manipulative Treatment May Affect Spinal Fluid Flow: An MRI Study
his study aims to investigate whether Osteopathic Manipulative Treatment (OMT) affects cerebrospinal fluid (CSF) flow and glymphatic clearance in the human brain.
- Trial name
- NCT07629765
- Testing
- Osteopathic Manipulative Treatment (OMT)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Edward Via Virginia College of Osteopathic Medicine
Lumbar Disc Herniation
A Biomechanical Study of the Lumbar Intervertebral Disc by Lever Positioning Manipulation
Purpose of Study: The purpose of this clinical trial is the clinical efficacy of different trigger modes of lever positioning manipulation (LPM) for the treatment of lumbar disc herniation (LDH).
- Trial name
- NCT06872918
- Testing
- Lever positioning manipulation, Cluster of pseudo-manipulators, Mechanics and kinematics data acquisition of unilateral wrenching patterns in lever positioning manipulation
- Where
- China
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Cervicogenic Headache, Whiplash Injuries
Manipulation and Dry Needling in Patients With Cervicogenic Headache and WAD II
The purpose of this research is to compare two different approaches for treating patients with cervicogenic headaches associated with type II whiplash associated disorder: non-thrust mobilization and exercise versus thrust…
- Trial name
- NCT06502951
- Testing
- Dry Needling,Thrust Manipulation, Exercise,Non-thrust Mobilization
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Alabama Physical Therapy & Acupuncture
Non-Specific Low Back Pain
Spinal Mobilization and Manipulation for Nonspecific Low Back Pain
Low back pain is one of the most common musculoskeletal disorders worldwide and is a major cause of pain and disability. Manual therapy techniques such as spinal mobilization and spinal manipulation are frequently used together…
- Trial name
- SMM-LBP (NCT07749898)
- Testing
- Spinal Mobilization and Manipulation, Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Biruni University
Non Specific Neck Pain
Effects of Cervical SNAGs With and Without Thoracic Manipulation on Neck Pain and Disability in Smartphone Users
Non-specific neck pain is a pain and discomfort in the cervical spinal area that arises without trauma, clearly identifiable pathological cause such as fracture infection, nerve root compression, inflammatory disease or serious…
- Trial name
- NCT07909759
- Testing
- Cervical SNAGS and thoracic manipulation with conventional physiotherapy, Cervical SNAG Mobilization Alone + Conventional Physiotherapy
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- University of Management and Technology Lahore
Spinal Manipulation, Neck Pain
Chiropractic Care for Neck Pain: Comparing Diversified Technique and Drop Table Method
This study aims to compare the effects of two different chiropractic techniques, Diversified and Drop Table, on pain levels, cervical joint range of motion, and neck muscle strength in individuals with non-specific neck pain.
- Conditions
- Spinal Manipulation, Neck Pain, Non Specific Neck Pain, Chiropractic
- Trial name
- CDTDTM (NCT07034144)
- Testing
- Drop Table Technique, Cervical Spine Manipulation
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- SEFA HAKTAN HATIK
Cerebral Palsy (CP)
The Effect of Spinal Manipulation on Heart Rate Variability in Children With Cerebral Palsy.
This randomized, sham-controlled crossover trial aims to evaluate the immediate effects of spinal manipulation on heart rate variability in children with cerebral palsy.
- Trial name
- NCT07504640
- Testing
- Spinal manipulation
- Where
- Ukraine
- Volunteers
- 20 people
- Sponsor
- International Clinic of Rehabilitation, Ukraine
Neck Pain Musculoskeletal, Neck Pain Treatment
Validating a Clinical Prediction Rule to Guide Manual Therapy and Exercise for Neck Pain Relief
Neck pain is a common issue that can lead to long-term disability and lost work time for many individuals. Despite numerous studies, finding effective treatment strategies has been challenging.
- Conditions
- Neck Pain Musculoskeletal, Neck Pain Treatment, Cervicalgia
- Trial name
- NCT06906107
- Testing
- Cervical Manipulation, Exercise, Mobilization
- Where
- 4 sites in United States
- Volunteers
- 160 people
- Sponsor
- Baylor University
Chronic Low-back Pain
The METRIC Study Protocol
The goal of this clinical trial is to test the effects of spinal manipulative therapy in individuals with chronic primary low back pain and determine the neurophysiological mechanisms underlying pain relief.
- Trial name
- METRIC (NCT05986370)
- Testing
- lumbar spinal manipulative therapy, full spine spinal manipulative therapy
- Where
- Canada
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Université du Québec à Trois-Rivières
Lumbar Disc Herniation
Brain Connectomic Mechanisms of Spinal Manipulative Therapy on LDH Analgesia Based on Multimodal MRI
Low back and leg pain caused by lumbar disc herniation (LDH) is common. Lever positioning manipulation (LPM) is a spinal manual therapy used to relieve this pain, but how it affects the brain is unclear.
- Trial name
- NCT07728149
- Testing
- Active Lever Positioning Manipulation
- Where
- China
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Chronic Low Back Pain
Sequential and Comparative Evaluation of Pain Treatment Effectiveness Response
VETERANS ONLY. Chronic low back pain (cLBP) is common. Most Americans will have at least one episode of low back pain in their lifetimes.
- Trial name
- SCEPTER (NCT04142177)
- Testing
- Pain EASE, Tailored exercise, Continued Care and Active Monitoring
- Where
- 19 sites in United States
- Volunteers
- 2,529 people
- Sponsor
- VA Office of Research and Development
Spine Condition, Low Back Pain
Influence of Flexion Distraction Manipulation on Measures of Performance and Postural Control
This research study will evaluate human performance and postural balance changes during the course of care with flexion distraction manipulation in multiple chiropractic practices.
- Trial name
- NCT06965920
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Keiser University College of Chiropractic Medicine
Low Back Pain
Neuroscience Education and Spinal Manipulation on Health Locus of Control in Low Back Pain
The purpose of this study is to evaluate the effects of combining Pain Neuroscience Education (PNE) with spinal manipulation for individuals suffering from chronic low back pain.
- Trial name
- LHC-LBP (NCT07639216)
- Testing
- Pain Neuroscience Education (PNE), Spinal Manipulation (SM)
- Where
- Brazil
- Volunteers
- 74 people
- Sponsor
- Centro Universitário Augusto Motta
Low Back Pain
Perspectives on Spinal Manipulative Therapy for Low Back Pain
The goal of this study is to better understand how the thoughts and beliefs of patients with low back pain and their physical therapist influence how much patients benefit from physical therapy.
- Trial name
- NCT06590116
- Testing
- Physical therapy, Physical therapist provider
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Florida
Back Pain Lower Back Chronic
Evaluation of the Short-term Effectiveness of Spinal Manipulation to Treat Acute and Subacute Low Back Pain.
Low back pain is the second most common reason for medical consultation in France and affects 60 to 80% of the working population.
- Trial name
- MeLoPe (NCT07403500)
- Testing
- Spinal or peripheral manipulation of the lower back to treat lower back pain
- Where
- France
- Volunteers
- 416 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Neck Pain
Normalizing Cervical Intersegmental Kinematics With Spinal Manipulative Therapy
The broad long-term objective is to develop an objective biomarker for spinal health based on aberrant or abnormal movement patterns during functional activities to better target spinal manipulation therapy (SMT) and other…
- Trial name
- NCT06312696
- Testing
- SMT, Light Massage
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Minnesota
Knee Stiffness After Total Knee Arthroplasty
Flex Appeal: Evaluating the Efficacy of Anesthetic Techniques for Manipulation of Knees Under Anesthesia
The purpose of this study is to determine if changing the type of anesthesia improves the outcomes of manipulation and pain control after the procedure.
- Trial name
- NCT07348614
- Testing
- Spinal Anesthesia, General Anesthesia, Propofol
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Duke University
Chronic Low-back Pain, Back Disorder
Movement Performance in Persons With Chronic Back Pain
The goal of this laboratory-based cross-over randomized controlled study is to study the immediate effects Spinal manipulative therapy (SMT) and exercise therapy (ET) compared to open-label placebo (OLP) on movement performance…
- Trial name
- NCT06891625
- Testing
- SMT, ET, OLP
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet