Clinical trials: Spinal Nerve Root Disorder Nos
Cervical Degenerative Disc Disease
Multi-Centre Post-Market Data Collection
This is a real world data collection observational study at a single site. There are both prospective and retrospective cohorts.
- Trial name
- NCT06413225
- Testing
- Synergy cervical disc system
- Where
- 2 sites in United Kingdom
- Sponsor
- Synergy Spine Solutions
Lumbosacral Radiculopathy
Study to Evaluate the Efficacy and Safety of BIIB074 in Neuropathic Pain From Lumbosacral Radiculopathy
The primary objective of the study is to evaluate the efficacy of two dose regimens of BIIB074 on neuropathic pain in participants with pain from lumbosacral radiculopathy (PLSR).
- Trial name
- RELAY-1 (NCT02935608)
- Testing
- BIIB074
- Where
- 56 sites in Austria, Belgium and 12 more
- Volunteers
- 502 people
- Sponsor
- Biogen
Cervical Radiculopathy
Association Between Neck Disability Index Categories and Multidirectional Range of Motion in Patient With Cervical Radiculopathy
This study aims to investigate the association between NDI categories (None, Mild, Moderate, Severe) and ROM in six directions: flexion, extension, right and left side bending, and right and left rotation.
- Trial name
- NCT07152522
- Testing
- cross sectional observational
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Low Back Pain, Radiculopathy Lumbar
The Effect of Accelerometer Guided App Feedback on Change in Activity in Patients With Low Back
In a cross-over, open-label, randomized, controlled trial, the investigators aim to determine if the daily activity level in patients with LBP can be increased via feedback from an app, connected to a wearable sensor of physical…
- Conditions
- Low Back Pain, Radiculopathy Lumbar, Sciatica
- Trial name
- NCT04695912
- Testing
- The SENS motion® sensor
- Where
- Denmark
- Volunteers
- 98 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cervical Radiculopathy
Anterior and Posterior Decompression Surgery in Individuals with Cervical Radiculopathy and Headache
This is a prospective observational register-based cohort study with 2 years follow-up with data from the national Swedish Spine Register (Swespine).
- Trial name
- NCT06113263
- Testing
- Anterior cervical decompression surgery, Posterior cervical foraminotomy with or without laminectomy
- Volunteers
- 2,889 people
- Sponsor
- Linkoeping University
Sciatica
Topiramate in the Treatment of Sciatica
This study will test the effectiveness of topiramate to treat pain caused by lumbar radiculopathy, or sciatica. Sciatica results from damage to the lumbar nerve roots, typically causing back pain and sharp, shooting pain down one…
- Trial name
- NCT00011804
- Testing
- Topiramate
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Degenerative Intervertebral Discs, Sciatic Radiculopathy
Eplerenone as a Supplement to Epidural Steroid Injections
Low back pain is a leading cause of disability and health care costs in the United States, and treatments are ineffective for many patients.
- Conditions
- Degenerative Intervertebral Discs, Sciatic Radiculopathy, Low Back Pain
- Trial name
- NCT03418649
- Testing
- Eplerenone 50 Mg Tab
- Where
- 2 sites in United States
- Sponsor
- University of Cincinnati
Cervical Radiculopathy
Rotation-traction Manipulation of Different Treatment Frequency in Cervical Radiculopathy
The evidence for different frequencies of rotation-traction manipulation treatment in cervical radiculopathy is insufficient. This study determined whether 3 sessions per week of rotation-traction manipulation treatment are…
- Trial name
- NCT06320249
- Testing
- High-frequency rotation-traction manipulation, Low-frequency rotation-traction manipulation, Cervical traction
- Where
- China
- Volunteers
- 216 people
- Sponsor
- Wangjing Hospital, China Academy of Chinese Medical Sciences
Cervical Radiculopathy
Effect of Core Stabilization Exercises on Patients With Cervical Radiculopathy
The goal of this clinical trial is to evaluate the effect of core stabilization exercise on functional outcome and craniovertebral angle which is the angle of forward head , in adults with cervical radiculopathy.
- Trial name
- NCT07365917
- Testing
- Core stabilization exercises, conventional physical therapy program
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Back Pain
Cytology Study of Cells From Patients With Low Back Pain
The investigators are doing this study to learn more about the cause of back pain with or without pain shooting down one or both legs.
- Trial name
- NCT01089478
- Volunteers
- 605 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Spinal Disease, Spinal Radiculopathy
This Study is to Determine if Degenerative Spinal Pain and Disorders Cause the Levels of Substance P to Change in a Patients Saliva, Blood and/or Cerebrospinal Fluid.
The objective of this pilot study is to determine if degenerative spinal disorders such as acute radiculopathy, myelopathy, stenosis, or disc and facet disease cause detectable alterations in Substance P levels in saliva, serum…
- Conditions
- Spinal Disease, Spinal Radiculopathy, Myelopathy, Neurogenic Claudication
- Trial name
- Substance P (NCT01458938)
- Testing
- treatment plan
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Carolina Neurosurgery & Spine Associates
Osteoarthritis Hand, Lumbago
Cardiovascular Risk in Digital Osteoarthritis
The goal of this cross-sectional case control study is to investigate the cardiovascular risk in digital osteoarthritis. This study aims to compare the cardiovascular risk between group of patients with digital osteoarthritis and…
- Conditions
- Osteoarthritis Hand, Lumbago, Osteoporosis, Radiculopathy Lumbar
- Trial name
- RICARDI (NCT05923736)
- Testing
- Intima media thickness ultrasound, hand ultrasound, EndoPAT™ 2000 system
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Clermont-Ferrand
Cervical Radiculopathy
Effect of Cervical Multifidus Muscle Area on Interlaminar Epidural Steroid Injection Outcomes
Cervical radiculopathy is one of the most important causes of chronic neck pain. Cervical epidural steroid injections including interlaminar approach are frequently used for treatment option in patients that more conservative…
- Trial name
- NCT05960487
- Testing
- Cervical multifidus muscle area measurement at 3 levels (C4-C5, C5-C6, C6-C7)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Marmara University
Lumbar Disc Herniation, Radiculopathy Lumbar
Non-pharmacological Treatment and Pharmacological Treatment for Non-acute Lumbar Disc Herniation
This study is a 2-armed parallel, multi-centered, pragmatic clinical trial that compares the comparative effectiveness of non-pharmacological treatment and pharmacological treatment for non-acute lumbar disc herniation.
- Trial name
- NCT05003726
- Testing
- non-pharmacological treatment, pharmacological treatment
- Where
- 4 sites in South Korea
- Volunteers
- 36 people
- Sponsor
- Jaseng Hospital of Korean Medicine
Cervical Radiculopathy
The Relationship Between Cervical Radiculopathy and Eye-hand Coordination
this study will be conducted to investigate if there is a relationship between cervical radiculopathy and eye-hand coordination.
- Trial name
- CR (NCT06169618)
- Testing
- cervical radiculopathy, normal group
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cervical Spondylosis With Myelopathy, Cervical Radiculopathy
Comparison of Artificial Disc Implants in Cervical Disc Arthroplasty
This study will comprehensively evaluate the outcomes and endpoints of these two different FDA-approved artificial disc implants used to treat cervical spondylotic myelopathy and/or radiculopathy today: Biomet Zimmer Mobi-C and…
- Conditions
- Cervical Spondylosis With Myelopathy, Cervical Radiculopathy, Cervical Disc Herniation, Degenerative Disc Disease
- Trial name
- NCT05701059
- Testing
- Cervical arthroplasty, Semi-Constrained Nuvasive Simplify, Unconstrained Biomet Zimmer Mobi-C
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, Los Angeles
Radiculopathy
Trial of Efficacy and Safety of Pregabalin in Subjects With Neuropathic Pain Associated With Lumbo-Sacral Radiculopathy
Trial will evaluate the efficacy and safety of pregabalin in the treatment of subjects with neuropathic pain associated with lumbo-sacral radiculopathy.
- Trial name
- NCT00159705
- Testing
- pregabalin
- Where
- 52 sites in United States, Belgium and 6 more
- Volunteers
- 276 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Cervical Radiculopathy, Radicular Pain
Comparing Two Different Cervical Collars for the Treatment in Patient With Cervical Radiculopathy and Radicular Pain
The primary objective of the study is to investigate the efficacy of device with far-infrared (FIR) irradiation in these patients with acute cervical radiculopathy.
- Conditions
- Cervical Radiculopathy, Radicular Pain, Acute Neck Pain, Cervicobrachial Pain
- Trial name
- NCT00880828
- Testing
- FIR cervical collar with Acetaminophen, Conservative cervical collar with Acetaminophen, Acetaminophen only
- Where
- Taiwan
- Volunteers
- 72 people
- Sponsor
- Taipei Medical University WanFang Hospital
Cervical Degenerative Disc Disease
Real World Data Collection on the Synergy Disc
This is a real world data collection observational study at a single site. There are both prospective and retrospective cohorts.
- Trial name
- NCT06383949
- Testing
- Synergy Cervical Disc system
- Where
- Ireland
- Volunteers
- 50 people
- Sponsor
- Synergy Spine Solutions
Cervical Radiculopathy
Effects of Thoracic Screw Manipulation in Patients With Cervical Radiculopathy
Cervical radiculopathy is a pain and/or sensorimotor deficit syndrome that is defined as being caused by compression of a cervical nerve root.
- Trial name
- NCT05749835
- Testing
- Thoracic Manipulation and Sustained Natural Apophyseal Glides and conventional therapy, Sustained Natural Apophyseal Glides and conventional therapy
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University