Clinical trials: Spinal Nerve Root Disorder Nos
Lumbosacral Radiculopathy
Effect of Thoracic Mobilization on Lumbar Radiculopathy
The purpose of the study will be to: To investigate the effect of thoracic mobilization on back and leg pain in patients with lumbosacral radiculopathy.
- Trial name
- NCT06167044
- Testing
- thoracic mobilization
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Cairo University
Radiculopathy, Cervical, Myelopathy
A Study of Korean Society of Spine Surgery on the Outcomes of Anterior Cervical Discectomy and Fusion
The purpose of this study is firstly to determine the efficacy of cervical plate for anterior cervical discectomy and fusion using cervical cage, and secondly to investigate the determining factors for surgical outcomes.
- Trial name
- NCT01911013
- Testing
- anterior cervical discectomy and fusion, Cage and Plate, Cage alone
- Where
- 31 sites in South Korea
- Volunteers
- 500 people
- Sponsor
- Seoul National University Hospital
Pain, Back Pain
NUCYNTA (Tapentadol Immediate Release) Versus Oxycodone Immediate Release in the Treatment of Acute Low Back Pain
Evaluate how NUCYNTA (tapentadol) immediate release (IR) compares with oxycodone IR in the treatment of acute low back pain.
- Conditions
- Pain, Back Pain, Low Back Pain, Back Pain With Radiation
- Trial name
- NCT00986180
- Testing
- NUCYNTA, Oxycodone IR
- Where
- 74 sites in United States
- Volunteers
- 667 people
- Sponsor
- Ortho-McNeil Janssen Scientific Affairs, LLC
Lumbar Spinal Stenosis, Lumbar Disc Herniation
In Turkish Version Lumbar Spine Surgery Expectation Survey
The aim of this study was to determine the Turkish validity and reliability of Lumbar Spine Surgery Expectations Survey developed by Mancuso.
- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation, Lumbar Radiculopathy, Lumbar Fracture
- Trial name
- NCT04547075
- Testing
- Turkish validity and reliability
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Kutahya Health Sciences University
Pain, Acute
Low Dose Lignocaine Injections as a Treatment Option for Acute Lumbosacral Radiculopathy
Low back pain is one of the most common ailments that plagues patients, with nearly 80% of the population developing some form of back pain in their lifetime.
- Trial name
- NCT04215757
- Testing
- peripheral nerve block
- Where
- India
- Volunteers
- 60 people
- Sponsor
- All India Institute of Medical Sciences, Rishikesh
Radiculopathy
Effect of High-Power Laser Therapy on Disc Morphology and Functional Outcome in Patients With Cervical Radiculopathy
The study aims to evaluate the effectiveness of high-power laser therapy (HPLT) in patients with cervical radiculopathy, focusing on its impact on disc morphology, and overall functional activity
- Trial name
- NCT07661290
- Testing
- High-Power Laser Therapy (HPLT), Ultrasound, Interferential Current, and Hot Packs
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Cervical Radiculopathy
Qishe Pill for Cervical Radiculopathy
Radiculopathy generally presents with pain, numbness, or weakness in a dermatomal distribution. Cervical radiculopathy results from impingement on a nerve root by either spondylotic narrowing of the neural foramen or a lateral…
- Trial name
- NCT01274936
- Testing
- Qishe Pill
- Where
- 5 sites in China
- Volunteers
- 240 people
- Sponsor
- Shanghai University of Traditional Chinese Medicine
Radiculopathy, Cervical, Myelopathy Cervical
Pilot Study of ZetaFuse™ Bone Graft for the Treatment of Cervical Degenerative Disc Disease
The goal of this pilot clinical trial is to test the safety and preliminary performance of the ZetaFuse Bone Graft in patient requiring fusion of the C3-C7 vertebral bones due to pain or loss of neurological function.
- Conditions
- Radiculopathy, Cervical, Myelopathy Cervical, Neurological Abnormality, Disc Disease
- Trial name
- NCT05971329
- Testing
- Cervical Fusion (ZetaFuse™ Bone Graft)
- Where
- 2 sites in Australia
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Zetagen Therapeutics, Inc
Lumbar Disc Herniation
Effectiveness of Core Stabilization Exercises With and Without Neural Mobilization Technique in Female Patients With Lumbar Radiculopathy Due to Disc Herniation - an RCT Study
Lumbar disc herniation (LDH) is the most frequent cause of lumbosacral radiculopathy and account for 39% of chronic low back pain cases. In approximately 95% of cases LDH occurs at L4-L5 and L5-S1 levels.
- Trial name
- NCT05663437
- Testing
- Core stabilization exercises, Core stabilization exercises + neural mobilization technique
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Dow University of Health Sciences
Chronic Ankle Injuries, Chronic Low-back Pain
Ankle Spine Syndrome "RAFFET Syndrome II
A case series aimed to describe a new clinical condition for the first time in the medical literature called Ankle Spine Syndrome or "RAFFET Syndrome II".
- Conditions
- Chronic Ankle Injuries, Chronic Low-back Pain, Lumbar Disc Herniation, Calf Muscle Weakness
- Trial name
- NCT06140862
- Testing
- calf muscle strengthening and streching
- Where
- Egypt
- Volunteers
- 1,000 people
- Sponsor
- Noha Khaled Shoukry
Lumbosacral Radiculopathy
Safety and Efficacy Study on AFA-281 for the Treatment of Low Back Pain
The goal of this clinical trial is to evaluate if the drug candidate AFA-281 works to treat chronic low back and leg pain caused by painful lumbosacral radiculopathy (PLSR) in adults.
- Trial name
- NCT06649747
- Testing
- AFA-281
- Volunteers
- 408 people
- Sponsor
- Afasci Inc
Low Back Pain
Interventional Study of Effects on Spine Height With Two Unloading Positions
The purpose of this study is to test a physical therapy intervention for reducing pain in the low back and into the legs. With individuals over the age of 40 years, this pain may be associated to changes in back height from aging…
- Trial name
- NCT01048749
- Testing
- aquatic vertical suspension., land-based supine flexion
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Texas Tech University Health Sciences Center
Cervical Radiculopathy
Cervical Traction, Passive Accessory Intervertebral Movements and Active Strength Training in Cervical Radiculopathy
To determine the effectiveness of Manual Cervical Traction, Passive Accessory Intervertebral Movements (PAIVMs) and Active strength training in the management of cervical radiculopathy.
- Trial name
- NCT05234268
- Testing
- Manual Cervical Traction, Passive Accessory Intervertebral Movements, Active Strength Training
- Where
- 2 sites in Pakistan
- Volunteers
- 51 people
- Sponsor
- Riphah International University
Cervical Radiculopathy
Acute Effect of Neural Mobilization in Cervical Radiculopathy: A Randomized Controlled Study
The aim of this study was to investigate the immediate effect of neural mobilization techniques, one of the manual therapy methods that can be used in the treatment of cervical radiculopathy.
- Trial name
- NCT05887427
- Testing
- Neural Mobilisation, Conservative physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Uskudar University
Cervical Myelopathy, Radiculopathy
Bone Marrow Aspirate Concentration in Posterior Cervical Fusion
The purpose of this research is to test if that combining bone marrow aspirate (removing bone marrow with a needle) concentration with locally harvested (collected) autograft (patient's own bone from another part of the body) for…
- Trial name
- BMAC (NCT02068547)
- Testing
- locally harvested autograft, demineralized bone matrix, and cadaveric allograft, Bone Marrow Aspirate
- Where
- 2 sites in United States
- Volunteers
- 8 people
- Sponsor
- Washington University School of Medicine
Radiculopathy
Study to Evaluate the Efficacy and Safety of Lenalidomide in the Treatment of Painful Lumbar Radiculopathy
The purpose of this multicenter, double-blind, placebo-controlled study is to evaluate the efficacy and safety of lenalidomide in the treatment of painful lumbar radiculopathy.
- Trial name
- NCT00120120
- Testing
- Lenalidomide (CC-5013)
- Where
- 23 sites in United States
- Volunteers
- 181 people
- Sponsor
- Celgene Corporation
Cervical Radiculopathy
Efficacy of a Combination of Conservative Treatments Compared to Isometric Exercise on Clinical Outcomes in Patients With Cervical Radiculopathy
This intervention study is to evaluate the efficacy of a combination of conservative treatments compared to isometric exercise on clinical outcomes in patients with cervical radiculopathy.
- Trial name
- NCT06276699
- Testing
- 1.Isometric exercise 2.combined conservative treatment
- Volunteers
- 46 people
- Sponsor
- University of Peradeniya
Neck Pain, Radiculopathy, Cervical
Repeated Transforaminal Anesthetic Injections With or Without Glucocorticoid in Patients With Cervical Radiculopathy
The main objective is to evaluate pain and muscle strength in the upper extremities after treatment with cervical transforaminal injection of glucocorticoid vs.
- Conditions
- Neck Pain, Radiculopathy, Cervical, Cervical Foraminal Stenosis, Cervical Disc Disease
- Trial name
- NCT03541681
- Testing
- Glucocorticoid Injections, Anesthetic Injections
- Sponsor
- Region Skane
Demyelinating Disorders, MCI
Exploring the Utility of [18F]3F4AP for Demyelination Imaging
The overall objective is to obtain an assessment of the pharmacokinetics of [18F]3F4AP in healthy volunteers and subjects with demyelinating diseases such as mild cognitive impairment (MCI), Alzheimer's Disease (AD), Multiple…
- Conditions
- Demyelinating Disorders, MCI, Alzheimer's Disease (AD), MS (Multiple Sclerosis)
- Trial name
- NCT06999434
- Testing
- [ 18F]3F4AP, [18F]MK6240, [11C]PIB
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Yale University
Low Back Pain
Evaluation of the Effectiveness of Transforaminal Epidural Injections in Lumbar Disc Herniation or Radiculitis
To evaluate differences in outcomes in patients receiving steroids compared to those patients randomized to the local anesthetic group who did not receive steroids.
- Trial name
- NCT01052571
- Testing
- lumbar transforaminal epidural injections
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Pain Management Center of Paducah