Clinical trials: Spinal Nerve Root Disorder Nos
Low Back Pain, Lumbosacral Radiculopathy
A Prospective Study to Compare Bupivacaine and Exparel Versus Bupivacaine or Exparel Alone for Postoperative Pain Relief
The purpose of this study is to collect information about how patients feel when doctors manage their pain after lumbar spine surgery using a combination of EXPAREL® and bupivacaine injected into the lumbar spine at the end of…
- Conditions
- Low Back Pain, Lumbosacral Radiculopathy, Lumbar Disc Degeneration, Lumbar Disc Herniation
- Trial name
- NCT03514277
- Testing
- Exparel, Bupivacaine
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Virtua Health, Inc.
Cervical Radiculopathy
Global Postural Re-Education And Neck Isometric Exercises In Cervical Radiculopathy RADICULOPATHY
Cervical radiculopathy is a common neurological disorder that is caused by compression of the nerve, inflammation of nerve roots, or space-occupying lesions.
- Trial name
- NCT06028958
- Testing
- Neck Isometrics Exercises, Global Posture Re-Education
- Where
- Pakistan
- Volunteers
- 85 people
- Sponsor
- University of Lahore
Cervical Radiculopathy
Shi-style Cervical Manipulations for Cervical Radiculopathy
Neck pain and related problems occur frequently in modern societies and have a considerable impact on individuals and the society.
- Trial name
- NCT01500967
- Testing
- Shi-style cervical manipulations, Cervical Traction control
- Where
- China
- Volunteers
- 648 people
- Sponsor
- Shanghai University of Traditional Chinese Medicine
Lumbar Radiculopathy, Magnetic Resonance Imaging
Diffusion Tensor (DTI) for the Assessement of Therapeutic Evolution of Patients With Acute Lumbar Radiculalgia
Diffusion tensor imaging (DTI) is a non-invasive MRI technique offering a functional approach that provides morphological information about the microstructures of the nerve roots.
- Conditions
- Lumbar Radiculopathy, Magnetic Resonance Imaging, Diffusion Tensor Imaging
- Trial name
- DiTi-Aïe (NCT04507113)
- Testing
- DTI sequence acquisition
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Lille Catholic University
Lumbosacral Radiculopathy
Does Magnetic Resonance Imaging (MRI) Improve Interventional Outcomes for Lumbosacral Radiculopathy?
Epidural steroid injections (ESI) are the most frequently performed procedures in pain clinics. When performing ESI, there is no consensus about how to best select candidates for this intervention, and which level(s) to inject.
- Trial name
- NCT00826124
- Testing
- Epidural steroid injection, Magnetic Resonance Imaging (MRI)
- Where
- 2 sites in United States
- Volunteers
- 131 people
- Sponsor
- Johns Hopkins University
Lumbar Radiculopathy, Discogenic Lumbosacral Radiculopathy
Effect of Trans-spinal Electromagnetic Neuromodulation in Treatment of Patients With Discogenic Lumbosacral Radiculopathy
Purposes of the study To investigate the effect of adding Trans-spinal Electromagnetic Neuromodulation to conventional physical therapy in patients with Discogenic Lumbosacral Radiculopathy
- Trial name
- NCT07743424
- Testing
- Trans-spinal Electromagnetic Neuromodulation, Conventional physical therapy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Yara Aboelazm Abd Elaziz Mohamed
Low Back Pain
Study of Cells From Spinal Cavity of Patients With Low Back Pain
The purpose of this study to determine if cells collected give us information about what is causing a patient pain can be detected and connected with epiduroscopy images (pictures taken with a small fiber optic scope).
- Trial name
- NCT01089491
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Lumbar Disc Prolapse With Radiculopathy
Pragmatic Randomized Controlled Trial of Non-pharmacological Treatment for Lumbar Disc Herniation : A Pilot Study
This is a 2-arm parallel pragmatic randomized controlled trial that will compare non-pharmacological treatment with pharmacological therapy for lumbar disc herniation.
- Trial name
- NCT04833270
- Testing
- KM non-pharmacological treatment group, Pharmacological treatment group
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Jaseng Hospital of Korean Medicine
Lumbosacral Radicular Syndrome
PRF Treatment for Patients With Chronic Lumbosacral Radicular Pain Compared to Conventional Medical Management
The purpose of the study is to evaluate the effect of PRF treatment adjacent to the lumbar dorsal root ganglion (DRG) of L5 or S1 in patients with a chronic lumbosacral radicular syndrome (LRS).
- Trial name
- NCT00991237
- Testing
- Pulsed Radiofrequency
- Where
- Netherlands
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Cervical Radiculopathy
Sustained Natural Apophyseal Glides and Mechanical Cervical Traction in the Management of Cervical Radiculopathy
Sustained natural apophyseal glides (SNAGS), is a form of manual therapy, involved a combination of a sustained facet glide with active motion, followed by overpressure.
- Trial name
- SNAG&MCT (NCT03362567)
- Testing
- Sustained Natural Apophyseal Glides, Mechanical Cervical Traction
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Obafemi Awolowo University
Degenerative Disc Disease, Degenerative Spondylolisthesis
The Five-repetition Sit-to-stand Test for Lower Back Pain or Radiculopathy
The five-repetition sit-to-stand test (5R-STS) has been used in many medical disciplines, but has never been correlated with or validated in regard to degenerative spinal diseases.
- Conditions
- Degenerative Disc Disease, Degenerative Spondylolisthesis, Herniated Disc, Stenosis, Spinal
- Trial name
- 5R-STS (NCT03303300)
- Where
- Netherlands
- Volunteers
- 237 people, healthy volunteers welcome
- Sponsor
- Marc Schröder
Lumbar Radiculopathy
Femoral Stretch Test in L2-L4 Lumbar Radiculopathy
This prospective observational study aims to evaluate the sensitivity of the femoral stretch test in patients with unilateral, single-root L2, L3, or L4 nerve root compression and to determine whether test positivity differs…
- Trial name
- NCT07799142
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Marmara University
Failed Back Surgery Syndrome, Degenerative Disk Disease
Spinal Cord Stimulation (SCS) Therapy Study
The purpose of this study is to evaluate the effect of different spinal cord stimulation settings in the treatment of leg pain. Subjects will receive a randomized order of four different programmed stimulation settings for 3…
- Conditions
- Failed Back Surgery Syndrome, Degenerative Disk Disease, Epidural Fibrosis, Arachnoiditis
- Trial name
- NCT02371122
- Testing
- Therapy Setting 1 (Medtronic), Therapy Setting 2 (Medtronic), Therapy Setting 3 (Medtronic)
- Sponsor
- MedtronicNeuro
Lumbar Radiculopathy, Lumbar Spinal Stenosis
The Impact of Contrast Media Used in Epidural Steroid Injections on Thyroid Function Tests
This study is aim to disclose the effect of contrast media, which used in epidural steroid injections, on the parameters of thyroid function tests (TFTs). The patients who underwent an epidural steroid injection were included.
- Conditions
- Lumbar Radiculopathy, Lumbar Spinal Stenosis, Cervical Radiculopathy, Cervical Stenosis
- Trial name
- NCT05404412
- Testing
- Epidural Steroid Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 124 people
- Sponsor
- Marmara University
Lumbosacral Radiculopathy
Effects of Mackenzie Extension and William Flexion Exercises in Lumbo-sarcal Radiculopathy
Lumbosacral radiculopathy (LR) is among most common disorder caused due to irritation or compression of nerve pathway leading to symptoms of pain, numbness and tingling sensations along the nerve root.
- Trial name
- NCT05654428
- Testing
- Mckenzie Extension Exercises, William Flexion Exercises
- Where
- Pakistan
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Neuro Counsel Hospital, Pakistan
Radiculopathy, Spondylolisthesis
Spondylolisthesis Treated With an iO-Flex® System Enabled Decompression
The purpose of this study is to evaluate the clinical performance of a decompression using the FDA cleared iO-Flex® System on-label in treating patients with spinal stenosis and stable grade I degenerative lumbar…
- Conditions
- Radiculopathy, Spondylolisthesis, Lumbar Spinal Stenosis
- Trial name
- STRiDE (NCT01338766)
- Testing
- Decompression using the iO-Flex® system
- Where
- 14 sites in United States
- Volunteers
- 100 people
- Sponsor
- Baxano Surgical, Inc.
Delirium, Lumbar Radiculopathy
Shaping Anesthetic Techniques to Reduce Post-operative Delirium
The purpose of this study is to determine if light sedation with spinal anesthesia reduces the incidence of delirium compared to receiving general anesthesia during spinal surgery in older adults.
- Conditions
- Delirium, Lumbar Radiculopathy, Lumbar Osteoarthritis, Lumbar Spine Disc Degeneration
- Trial name
- SHARP (NCT03133845)
- Testing
- Light sedation with propofol, Induction with propofol, Maintenance anesthetic using a volatile anesthetic
- Where
- United States
- Volunteers
- 218 people
- Sponsor
- Johns Hopkins University
Chronic Neuropathic Pain, Post-Stroke Pain
Transcranial Magnetic Stimulation for Chronic Neuropathic Pain
Chronic neuropathic pain is defined as pain caused by a lesion or disease of the somatosensory nervous system. It is highly prevalent, debilitating, and challenging to treat.
- Conditions
- Chronic Neuropathic Pain, Post-Stroke Pain, Trigeminal Neuralgia, Nerve Injury
- Trial name
- NCT05593237
- Testing
- High Frequency rTMS, Low Frequency rTMS
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of California, San Francisco
Clinical Radiculopathy, Myelopathy Due to a Cervical Disk Disease
Arthroplasty Versus Fusion in Anterior Cervical Surgery: Prospective Study of the Impact on the Adjacent Level
The aim of the study is to evaluate the impact of the cervical disk surgery on the deterioration of the adjacent levels. The investigators compare the radiological deterioration of adjacent levels, at 3 years, in both situation…
- Trial name
- PROCERV (NCT00554528)
- Testing
- cervical disc prosthesis with a mobile insert named Mobi-C, arthrodesis - cervical disk surgery
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Radiculopathy Lumbar
High Tone Power Therapy on Lumbosacral Radiculopathy Patients
to investigate the effect of High Tone Power Therapy on Pain, Range of Motion and Quality of Life in Lumbosacral Radiculopathy Patients
- Trial name
- NCT07305792
- Testing
- High tone power therapy, selected physical therapy program
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- October 6 University