Clinical trials: Spinal Pain Syndrome
Failed Back Surgery Syndrome
Study Comparing Conventional, Burst and High Frequency (HF) Spinal Cord Stimulation (SCS) in Refractory Failed Back Surgery Syndrome (FBSS) Patients After a 32-contact Surgical Lead Implantation
Chronic Back and/or Leg Pain (CBLP) after spinal surgical procedures, a condition commonly labelled Failed Back Surgery Syndrome (FBSS), affects between 15% and 40% of patients after a spine surgery.
- Trial name
- MULTIWAVE (NCT03014583)
- Testing
- Precision Spectra™ system
- Where
- France
- Volunteers
- 28 people
- Sponsor
- Poitiers University Hospital
Failed Back Surgery Syndrome
pRedicting the Long-term rEsponse of High Frequency sPinal cOrd sTimulation in Patients With Failed Back Surgery Syndrome.
The aim of the current retrospective study is to predict responders for HF10-SCS therapy by only using baseline data. Data collected through clinical practice until June 2020 will be used in this retrospective analysis.
- Trial name
- REPORT (NCT04500691)
- Testing
- pain intensity reporting
- Where
- 2 sites in Belgium
- Volunteers
- 122 people
- Sponsor
- Moens Maarten
Cervical Spine Syndrome
Effectiveness of Various Electrotherapy Methods in Treating People With Cervical Spine Pain Syndrome.
Volunteers will take part in the study; Students of the university in the area of Rzeszow reporting chronic spinal ailments participation in remote learning.
- Trial name
- NCT04890743
- Testing
- Kinesiotherapy combined with electrotherapy (Convenctional TENS method)., Kinesiotherapy combined with electrotherapy (Pseudo-acupuncture TENS method)., Kinesiotherapy combined with electrotherapy (Trabert ultrastimulation method)
- Where
- Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Rzeszow
Chronic Pain, Chronic Pain Syndrome
Outcomes Mandate National Integration With Cannabis as Medicine
This will be a multistate, multicenter clinical study to determine the efficacy and safety of medical cannabis for a wide variety of chronic medical conditions.
- Conditions
- Chronic Pain, Chronic Pain Syndrome, Chronic Pain Due to Injury, Chronic Pain Due to Trauma
- Trial name
- OMNI-Can (NCT03944447)
- Testing
- Cannabis, Medical, RYAH-Medtech Inhaler
- Where
- 17 sites in United States
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- OMNI Medical Services, LLC
Chronic Pain, Sciatica
NAPS: Non-awake Versus Awake Placement of Spinal Cord Stimulators
The primary objective is to demonstrate the safety and efficacy of a non-awake implantation method (EMG neuromonitoring) of a SCS paddle lead as compared to an awake implantation method (with local anesthesia and patient…
- Conditions
- Chronic Pain, Sciatica, Failed Back Surgery Syndrome
- Trial name
- NAPS (NCT02284542)
- Testing
- Awake, Non-Awake
- Where
- 4 sites in United States
- Volunteers
- 34 people
- Sponsor
- St. Luke's Hospital, Pennsylvania
Subacromial Pain Syndrome
Dry Needling and Manipulation vs. Mobilization, Exercise and Interferential Electrotherapy for Shoulder Impingement (Subacromial Pain Syndrome)
The purpose of this research is to compare two different approaches for treating patients with shoulder impingement (subacromial pain syndrome): electric dry needling and spinal manipulation versus impairment-based mobilization…
- Trial name
- NCT03168477
- Testing
- dry needling, spinal manipulation, mobilization
- Where
- United States
- Volunteers
- 145 people
- Sponsor
- Alabama Physical Therapy & Acupuncture
Failed Back Surgery Syndrome
High-density in Spinal Cord Stimulation: Virtual Expert Registry
This is a prospective, multi-center, observational follow-up study observing the effectiveness of high density spinal cord stimulation in patients with failed back surgery syndrome patients with back and leg pain.
- Trial name
- Discover (NCT02787265)
- Testing
- spinal cord stimulation
- Where
- Belgium
- Volunteers
- 272 people
- Sponsor
- Universitair Ziekenhuis Brussel
Failed Back Surgery Syndrome, Spinal Stenosis
Value of Three-dimensional Rotational Epidurography on Percutaneous Epidural Adhesiolysis
Conventional epidurography (CE) is thought to have insufficient usefulness on percutaneous epidural adhesiolysis (PEA). The investigators aimed to evaluate the association between the outcome of PEA and three…
- Trial name
- NCT04216992
- Testing
- Cone beam computed tomography
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Postpoliomyelitis Syndrome
Arm Cycling to Improve Fitness in Polio Survivors
The aim of this study is to investigate the effect of upper limb cardiovascular training on fitness, energy cost of walking, fatigue and pain in polio survivors.
- Trial name
- NCT01271530
- Testing
- Upper Limb Ergometry
- Where
- Ireland
- Volunteers
- 55 people
- Sponsor
- Royal College of Surgeons, Ireland
Chronic Pelvic Pain Syndrome
Prospective Evaluation of Effectiveness and Safety of Closed-Loop Spinal Cord Stimulation in Treating Patients With Chronic Pelvic Pain
Spinal cord stimulation (SCS) is an effective treatment for patients with chronic pelvic pain. The investigators will evaluate how safe and effective closed-loop spinal cord stimulation is in treating these patients; closed-loop…
- Trial name
- NCT06377969
- Testing
- ECAP (Evoked Compound Action Potential)-controlled Closed-Loop Spinal Cord Stimulation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Stanford University
Chronic Pain
Optimal Stimulation Programming for Spinal Peripheral Neuromodulation
To determine the best parameters with various leads to cover back and leg pain and provide best pain relief
- Trial name
- NCT02346383
- Testing
- preset program
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Carolinas Center for Advanced Management of Pain
Failed Back Surgery Syndrome
Subthreshold SCS or BMT
Given the substantial socioeconomic impact of Spinal Cord Stimulation (SCS) implantations and given that currently no direct high-quality evidence with a relevant outcome measurement is available to guide the treatment choice…
- Trial name
- TRADITION (NCT05169047)
- Testing
- Best Medical Treatment, Subthreshold Spinal Cord Stimulation
- Where
- 5 sites in Belgium
- Volunteers
- 114 people
- Sponsor
- Moens Maarten
Persistent Spinal Pain Syndrome
Patient Preference and Long-term Outcomes in Persistent Spinal Pain Syndrome: A Prospective Study Comparing Spinal Cord Stimulation to Intrathecal Drug Delivery.
Spinal cord stimulation (SCS) or intrathecal drug delivery (pain pump) can be effective in providing pain relief for patients with low back pain who have not responded to other treatments.
- Trial name
- NCT07091123
- Testing
- Pain pump, Bupivacain 0.625%/Fentanyl 2mcg/ml, Spinal Cord Stimulator (SCS)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University Hospitals Cleveland Medical Center
Complex Regional Pain Syndrome
Comparison of Dorsal Column Stimulation to Dorsal Root Ganglion Stimulation for Complex Regional Pain Syndrome
Complex Regional Pain Syndrome (CRPS) is a constellation of pain symptoms which are associated with impairment in mood, social and physical function.
- Trial name
- NCT03794024
- Testing
- The Nuvectra Algovita Dorsal Column Spinal Cord Stimulator, The Axium Neurostimulator System
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- The Cleveland Clinic
Chronic Pain
Algovita Post-Market Clinical Study: Spinal Cord Stimulation to Treat Chronic Pain
The purpose of this study is to obtain real-world clinical outcome data for the Algovita Spinal Cord Stimulation system when used, on-label, according to the applicable directions for use.
- Trial name
- NCT02373540
- Testing
- Algovita Spinal Cord Stimulation system
- Where
- 18 sites in United States, Germany
- Volunteers
- 91 people
- Sponsor
- Nuvectra
Failed Back Surgery Syndrome
Sweat Gland Function in Patients With Failed Back Surgery Syndrome, Treated With Spinal Cord Stimulation
This study is investigating sweat gland function during on and off states of the spinal cord stimulator, in patients with failed back surgery syndrome.
- Trial name
- NCT04668482
- Testing
- SCS is switched off, SCS is switched on
- Where
- Belgium
- Volunteers
- 23 people
- Sponsor
- Universitair Ziekenhuis Brussel
Shoulder Impingement
Effects of PNF on Shoulder Pain in Paraplegic Manual Wheel Chair Users
This project was a Randomized control trial conducted to check the Effects of Proprioceptive Neuromuscular Facilitation on Shoulder Pain due to chronic impingement syndrome in paraplegic Manual Wheelchair users after Spinal Cord…
- Trial name
- NCT04967911
- Testing
- Rhythmic stabilization exercises, conventional treatment
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- Riphah International University
Failed Back Surgery Syndrome, Post-Laminectomy Syndrome
SENSE (Subcutaneous and Epidural Neuromodulation System Evaluation) Study
The purpose of the study is to demonstrate safety and efficacy of spinal cord stimulation with peripheral nerve field stimulation for the treatment of chronic low back and leg pain.
- Conditions
- Failed Back Surgery Syndrome, Post-Laminectomy Syndrome, Low Back Pain
- Trial name
- SENSE (NCT01990287)
- Testing
- SCS and PNfS, SCS Alone
- Where
- 28 sites in United States
- Volunteers
- 38 people
- Sponsor
- Abbott Medical Devices
Lumbar Disc Herniation, Lumbar Discogenic Pain
Comparing General Anesthesia, General Anesthesia With ESP Block or TLIP Block in Patients Undergoing Lumbar Surgeries
The regional methods of anesthesia for the neurosurgical operations of the spine and spinal cord reducing the needs for opioids intra operatively and reducing pain in the postoperative period, decrease the numbers of failed back…
- Conditions
- Lumbar Disc Herniation, Lumbar Discogenic Pain, Lumbar Spinal Stenosis, Failed Back Surgery Syndrome
- Trial name
- NCT05447780
- Testing
- regional anesthesia
- Where
- Ukraine
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Anesthesia Research Group UA
Chronic Pain, Neuropathic Pain
Intraoperative Neuromonitoring Recording With a Novel SCS Paddle
The purpose of this study is to demonstrate safety and efficacy of a new spinal cord stimulation paddle electrode which is able to target the dorsal horns, dorsal nerve roots, and dorsal columns.
- Conditions
- Chronic Pain, Neuropathic Pain, Failed Back Surgery Syndrome, Complex Regional Pain Syndromes
- Trial name
- NCT05045625
- Testing
- HD Study Electrode
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Albany Medical College