Clinical trials: Spinal Trauma
Osteoporotic Vertebral Fracture
The Influence of Vertebral Mobility on Low Back Pain in Patients With Acute Osteoporotic Vertebral Fractures
Many patients with acute osteoporotic vertebral fracture (acute OVFs) admitted because of low back pain. But there are only part of patients with acute OVFs, because some patients do not have low back pain although OVFs occurred.
- Trial name
- NCT01990365
- Where
- Japan
- Volunteers
- 300 people
- Sponsor
- Tomidahama Hospital
Spinal Cord Injury at C4-C6 Level
High Definition Neuromuscular Stimulation in Tetraplegia
The purpose of this study is to demonstrate high definition non-invasive neuromuscular stimulation of an upper extremity in tetraplegic participants.
- Trial name
- NCT04075812
- Testing
- Neuromuscular Stimulator
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Ohio State University
Sleep Disorder
Sleep Quality & Spinal Cord Injury
The aim of the study was to evaluate sleep quality in patients with spinal cord injury; to investigate the relationship between sleep and spinal cord level, ambulation status, spasticity, quality of life, daily living activities…
- Trial name
- SLP (NCT04161612)
- Testing
- Demographic characteristics, duration of spinal cord injury, spinal cord injurylevel, etiology, number of intermittent bladder catheterization (IC), number of night time
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Acute Spinal Cord Injury
Mean Arterial Blood Pressure Treatment for Acute Spinal Cord Injury
Current guidelines for the clinical management of acute spinal cord injury (SCI) recommend maintenance of mean arterial blood pressure (MAP) at 85 to 90 mmHg for the first seven days after SCI as a clinical option.
- Trial name
- MAPS (NCT02232165)
- Testing
- Hypotension avoidance, Induced hypertension
- Where
- 2 sites in United States, Canada
- Volunteers
- 17 people
- Sponsor
- University of Calgary
Healthy Volunteers, Spinal Cord Injury
Chronic Transcutaneous Stimulation to Promote Motor Function and Recovery in Individuals With Paralysis or Paresis
This is an early feasibility trial to determine whether transcutaneous neuromuscular electrical stimulation, with or without transcutaneous spinal cord stimulation, using an investigational neurostimulation device improves…
- Conditions
- Healthy Volunteers, Spinal Cord Injury, Stroke, Paralysis
- Trial name
- NCT04755699
- Testing
- Transcutaneous Electrical Stimulation
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Thoracic Spinal Cord Injury
Safety of CRT100 on Treatment Spinal Cord Injury
The goal of this clinical trial is to test CRT100 treatment in participants with acute thoracic spinal cord injury. The main questions it aims to answer is safety of CRT100.
- Trial name
- CRT100 (NCT05739734)
- Testing
- CRT100
- Where
- 3 sites in Brazil
- Volunteers
- 5 people
- Sponsor
- Cristália Produtos Químicos Farmacêuticos Ltda.
Spinal Cord Injuries
Effect of a Novel Intervention Using Daily Intermittent Hypoxia and High Intensity Training on Upper Limb Function in Individuals With Spinal Cord Injury
Currently, there are a variety of approaches utilized in attempts to improve upper extremity function, including: traditional therapy, neuroprostheses, botulinum toxin injections, or surgical interventions.
- Trial name
- NCT03643770
- Testing
- Upper extremity training/Armeo Spring
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Shirley Ryan AbilityLab
Spinal Cord Injury Cervical, Spinal Cord Injury Thoracic
A Study to Evaluate the Safety of a Delivery Device for Administering LCTOPC1 in Participants With Spinal Cord Injury
The DOSED clinical study evaluates the safety and utility of a novel delivery device to deliver LCTOPC1, a cell therapy, to the spinal cord of patients with a spinal cord injury (SCI).
- Conditions
- Spinal Cord Injury Cervical, Spinal Cord Injury Thoracic, Spinal Cord Injury, Acute, Spinal Cord Injury
- Trial name
- DOSED (NCT06841770)
- Testing
- OPC1
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Lineage Cell Therapeutics, Inc.
Spinal Cord Injuries, Spinal Cord Diseases
Vaporized Cannabis and Spinal Cord Injury Pain
This study will demonstrate that vaporized marijuana results in antinociception when compared to placebo in subjects with spinal cord injury.
- Trial name
- NCT01555983
- Testing
- Vaporization of Cannabis
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Barth Wilsey
Spinal Cord Injuries, Spinal Cord Injury at C5-C7 Level
Brain Plus Spinal Stimulation for Cervical SCI
The goal of this project is to strengthen residual corticospinal tract (CST) connections after partial injury using combined motor cortex and spinal cord stimulation to improve arm and hand function after spinal cord injury…
- Conditions
- Spinal Cord Injuries, Spinal Cord Injury at C5-C7 Level, Tetraplegia/Tetraparesis
- Trial name
- NCT04727866
- Testing
- transcutaneous spinal direct current stimulation (tsDCS) - coronal, transcutaneous spinal direct current stimulation (tsDCS) - caudal, transcutaneous spinal direct current stimulation (tsDCS) - rostral
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bronx VA Medical Center
Postoperative Pain, Spine Deformity
Intraoperative Placement of Superficial Erector Spinae Plane Block; A New Approach in Spine Surgery
Major spine surgery causes severe postoperative pain. The primary objective of this randomized controlled study is to compare the effect of ultrasound (US)-guided superficial erector spinae plane (ESP) block on 48-hour…
- Conditions
- Postoperative Pain, Spine Deformity, Spine Injury, Spine Fracture
- Trial name
- NCT05244031
- Testing
- superficial erector spina plane block, Standard (opioid-based) analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Shoulder Pain, Spinal Cord Injury
Safe and Effective Shoulder Exercise Training in Manual Wheelchair Users With SCI
This study will compare two exercise programs in an interventional study for manual wheelchair users with spinal cord injury and shoulder pain.
- Trial name
- NCT02777281
- Testing
- Shoulder pain and SCI, Shoulder pain and able bodies
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Minnesota
Spinal Cord Injuries
The Effect of Locomotor Training on Children With Incomplete Spinal Cord Injuries
--Participation open to all Canadian residents-- The purpose of this study is to address how well children with incomplete spinal cord injuries of greater than 12 months duration who remain non-functional ambulators improve…
- Trial name
- NCT00931983
- Where
- Canada
- Sponsor
- McGill University
Adaptive Sport in Spinal Cord Injury
Study About Acting of Adaptive Sport in Musculoskeletal, Cardiovascular System and the Quality of Life of Individuals With Spinal Cord Injury Through Biomedical Instrumentation
The hypothesis is to the fulfillment of canoeing, handbike and conventional physiotherapy activities the groups could show improvement in muscle strength of the arms, decreased resistance of the lower limbs (spasticity), improved…
- Trial name
- Adaptive sport (NCT02177929)
- Testing
- adapted canoeing, hadbike and conventional physiotherapy
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- Universidade do Vale do Paraíba
Wheelchair, Paraplegia
Virtual Peer Coaching in Manual Wheelchair Skills
The objective of this study is to determine the effectiveness of remote manual wheelchair skills training program. First, peer coaches will be enrolled and trained.
- Conditions
- Wheelchair, Paraplegia, Spinal Cord Injury, Tetraplegia/Tetraparesis
- Trial name
- NCT06295146
- Testing
- Intervention A: 1-on-1 wheelchair skills training by a peer coach, Intervention B: Training via educational videos
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- University of Pittsburgh
Accidental Falls, Bone Fracture
Flooring for Injury Prevention Trial
This study will evaluate the efficacy of novel compliant flooring in reducing injuries due to falls in a long-term care facility, determine the cost effectiveness of this intervention, and assess perceptions about compliant…
- Conditions
- Accidental Falls, Bone Fracture, Traumatic Brain Injury, Head Injuries, Closed
- Trial name
- FLIP (NCT01618786)
- Testing
- SmartCell flooring, Plywood flooring
- Where
- Canada
- Volunteers
- 151 people
- Sponsor
- Dr. Stephen Robinovitch
Settings Word Prediction Software, Rehabilitation Program
Evaluation of the Efficiency of Word Prediction Software to Text Input Speed for Tetraplegia
Computers now play an important role in the lives of most individuals.Access to computers is crucial for people with disabilities and may improve their quality of life.
- Trial name
- Smartwrite (NCT01953666)
- Testing
- Rehabilitation program, Self - Training at home
- Where
- France
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Centre d'Investigation Clinique et Technologique 805
Spinal Cord Injuries, Tetraplegia
Human Factors Validation Testing of the Wandercraft Personal Exoskeleton
The goal of this interventional, national, prospective, open and monocentric study is to demonstrate that a personal exoskeleton can be used by the intended users without serious use errors or problems, for the intended uses and…
- Conditions
- Spinal Cord Injuries, Tetraplegia, Paraplegia
- Trial name
- ExoUser (NCT06715631)
- Testing
- Hands-free exoskeleton
- Where
- France
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Wandercraft
Spinal Cord Injury
Dietary Patterns and Cardiovascular (CVD) Risk in Spinal Cord Injury (SCI) Factors In Individuals With Chronic Spinal Cord Injury
This study will look at dietary patterns in individuals with chronic spinal cord injuries and the relationship between these dietary patterns and cardiovascular disease risk factors.
- Trial name
- SCIDS (NCT01025609)
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Spinal Cord Injuries
Reliability and Validity of the ISNCSCI in Patients With Non-traumatic Spinal Cord Lesions
Aim of the study is to assess the psychometric properties of the International Standards for Neurological Classification of Spinal Cord Injury in subjects with non traumatic lesions.
- Trial name
- NCT04949763
- Testing
- rehabilitation
- Volunteers
- 140 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia