Clinical trials: Spine Condition, open to volunteers
Low Back Pain
Effect of Lumbar Spine Correction Training on Postural Awareness and Stability in Patients With Low Back Pain
PURPOSE: to investigate The Efficacy of lumbar spine correction training on postural awareness and stability in patients with low back pain.
- Trial name
- NCT07552064
- Testing
- lumbar spine correction training, conventional treatment
- Volunteers
- 30 people
- Sponsor
- October 6 University
Spinal Diseases, Endoscopy Simulation
Comparing 3D and 2D Views in Biportal Spine Surgery: A Pilot Simulation Study
This study aims to compare three-dimensional (3D) and two-dimensional (2D) visualization in biportal endoscopic spine surgery using a simulated environment.
- Conditions
- Spinal Diseases, Endoscopy Simulation, Lumbar Vertebrae, Randomized Controlled Trial
- Trial name
- NCT07171801
- Testing
- Three-Dimensional Endoscopic Visualization, Two-Dimensional Endoscopic Visualization
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Felix Corr
Postoperative Pain, Spinal Fusion Surgery
TLIP Block Versus Retrolaminar Block on Quality of Recovery After Posterior Lumbar Spine Fusion Surgery
This prospective randomized controlled study aims to compare the effects of ultrasound-guided thoracolumbar interfascial plane (TLIP) block versus retrolaminar block on postoperative quality of recovery in patients undergoing…
- Conditions
- Postoperative Pain, Spinal Fusion Surgery, Degenerative Lumbar Spine Diseases
- Trial name
- TLIP-RLB-QoR (NCT07609212)
- Testing
- Thoracolumbar interfascial plane block, Retrolaminar block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Assiut University
Postoperative, Pain
Effect of Erector Spinae (ESP) Block on Opioid Reduction and Enhanced Recovery After Posterior Cervical Spine Surgery
Patients undergoing spine surgery frequently experience significant pain after surgery. This can limit patient activity and hinder rehabilitation.
- Trial name
- NCT04646707
- Testing
- Erector Spinae (ESP) Block with Lidocaine/Bupivacaine
- Where
- Canada
- Volunteers
- 52 people
- Sponsor
- University Health Network, Toronto
Post Operative Pain, Spinal Surgery
Methadone to Reduce Chronic Opioid Use After Major Spine Surgery: The MEND Pilot Feasibility Study
The investigators propose a randomized, triple-blinded (patients, investigators, outcomes assessors), placebo-controlled pilot feasibility trial (Methadone to End Narcotic Dependence, MEND trial) to assess the feasibility and…
- Trial name
- MEND (NCT07222072)
- Testing
- Methadone
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Spinal Stenosis Lumbar, Disc Herniation, Lumbar
More Realistic Spine Patients: Assessing the Effect of Dialogue Support Tool.
This multicenter randomized controlled trial will evaluate whether an additional preoperative study visit using the Dialogue Support (DS) tool improves patient information, expectations, and outcomes among adults scheduled for…
- Conditions
- Spinal Stenosis Lumbar, Disc Herniation, Lumbar, Degenrative Disc Disease
- Trial name
- MORESP (NCT07788872)
- Testing
- Dialogue Support Study Visit
- Where
- 2 sites in Norway
- Volunteers
- 440 people
- Sponsor
- University Hospital, Akershus
Radius; Deformity, Hip Osteoarthritis
Clinical Evaluation and Cost-effectiveness Analysis of 3D Digital Surgery in Traumatology
Digital surgery, in combination with patient specific instrumentation (PSI) is being used more and more in traumatology due to its proven benefits and applications.
- Conditions
- Radius; Deformity, Hip Osteoarthritis, Hip Arthritis, Hip Arthropathy
- Trial name
- NCT06603831
- Testing
- patients treated using 3D technology and Patient-Specific Instrumentation, Patients treated with conventional surgery, without using 3D technology
- Where
- Spain
- Volunteers
- 180 people
- Sponsor
- Corporacion Parc Tauli
Degenerative Cervical Myelopathy
Conservative Care Versus Decompression Trial for Degenerative Cervical Myelopathy Pilot
This study is a pilot randomized clinical trial designed to test whether it is feasible to conduct a larger study comparing two standard treatments for mild degenerative cervical myelopathy (DCM).
- Trial name
- CADET-DCM (NCT07358273)
- Testing
- Decompression Surgery, Conservative Care
- Volunteers
- 56 people
- Sponsor
- McMaster University
Low Back Pain
Assessment of the Evolution of Lumbar Spine Movement Fluidity Using Xsens Inertial Sensors in Subjects With Chronic Low Back Pain Before and After Rehabilitation
Low back pain, defined as pain located between the thoracolumbar junction and the lower gluteal fold, becomes chronic in 8% of patients.
- Trial name
- Xmouv (NCT07327554)
- Testing
- X-sens sensor
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Montpellier
Rib Fracture, Postoperative Pain
SPSIP vs ESP Block for Analgesia After Rib Fracture Surgery
This randomized clinical trial aims to evaluate and compare the analgesic efficacy of the Serratus Posterior Superior Intercostal Plane (SPSIP) block and the Erector Spinae Plane (ESP) block in patients undergoing surgical…
- Conditions
- Rib Fracture, Postoperative Pain, Thoracic Trauma
- Trial name
- NCT07553208
- Testing
- Erector Spinae Plane Block (ESP), Serratus Posterior Superior Intercostal Plane (SPSIP)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Antalya City Hospital
Spine Degeneration, Hip Arthritis
Evaluating the Efficacy of a Mobile Application in Postoperative Rehabilitation
This study aims to evaluate the effectiveness of a mobile application in improving postoperative rehabilitation outcomes among patients undergoing orthopedic surgery.
- Conditions
- Spine Degeneration, Hip Arthritis, Knee Osteoarthritis, Hip Fractures
- Trial name
- NCT06407427
- Testing
- App for in-bed conditioning exercises, Usual care
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Yale University
Low Back Pain, Spine Disease
Effect of an Interdisciplinary Spine Rehabilitation Program
The goal of this research project is to evaluate the effectiveness of the current interdisciplinary rehabilitation program (Revita) and follow-up trajectory for chronic lumbar spine disorders in the University Hospitals Leuven.
- Trial name
- PROGRESS (NCT06030570)
- Testing
- Rehabilitation program (Revita)
- Where
- Belgium
- Volunteers
- 90 people
- Sponsor
- KU Leuven
Spinal Cord Injuries
NeuroSuitUp: Neurorehabilitation Through Synergistic Man-machine Interfaces
NeuroSuitUp is a multidisciplinary neurophysiological \& neural rehabilitation engineering project, developed by the Lab of Medical Physics \& Digital Innovation, School of Medicine, Faculty of Health Science Aristotle University…
- Trial name
- NeuroSuitUp (NCT05465486)
- Testing
- Brain-Computer Interface control of robotic arms with augmented reality, Serious game with augmented reality
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Spine Tumor, Spine Metastases
Spine Oncology Registry
This is an observational study to evaluate hardware related and oncologic outcomes in adult patients with primary and metastatic spine disease undergoing separation surgery followed by radiation treatment.
- Conditions
- Spine Tumor, Spine Metastases, Spine Cancer
- Trial name
- NCT07225491
- Where
- 5 sites in United States
- Volunteers
- 3,000 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Spinal Stenosis of Lumbar Region, Spine Degeneration
Proteomic and Histological Analysis of Ligamentum Flavum in Lumbar Stenosis
Background Lumbar spinal stenosis (LSS) is a common condition characterized by spinal canal narrowing, often linked to ligamentum flavum hypertrophy (LFH) and degeneration.
- Trial name
- APIDeLeG (NCT07026552)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Degenerative Lumbar Spine Diseases
Digital Health for Lumbar Degeneration
This study will integrate wireless wearable sensors, smartphone imaging, and multimodal artificial intelligence (AI) to address the rehabilitation needs of patients with lumbar degeneration.
- Trial name
- NCT07133724
- Testing
- AI-Based Smart Assessment and Rehabilitation Training
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Intervertebral Disc Degeneration, Osteoarthritis, Spine
Open Access Database of Standing Full Body Radiographs in Asymptomatic Volunteers
A study of the skeletal structure and how the structure changes over time. The aim of the study is to evaluate the skeleton in 10 year increments to determine an understanding of the normal skeleton as a person ages.
- Trial name
- NCT03076658
- Testing
- EOS imaging
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Degenerative Disc Disease, Degenerative Scoliosis
Clinical Outcome Measure at Stryker Spine
This is a multicenter, prospective, retrospective, Post Market Clinical Follow-up (PMCF) study in subjects who have undergone or will undergo surgery utilizing one or more Stryker devices according to Stryker cleared Instructions…
- Trial name
- COMPASS (NCT06226272)
- Testing
- Spinal Fusion, Spinal Deformities Correction
- Where
- 7 sites in United States
- Volunteers
- 5,222 people
- Sponsor
- VB Spine, LLC
Temporomandibular Joint Disorders
Temporomandibular Joints Mobility and Head Posture: Influence of Manual Therapy and Exercises in Dental Patients.
Goal: This clinical study aims to investigate how the range of motion of the temporomandibular joints (TMJ) changes in relation to the patient's head posture.
- Trial name
- NCT07297251
- Testing
- Manual therapy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Jerzy Kukuczka Academy of Physical Education in Katowice
Plagiocephaly, Nonsynostotic, Brachycephaly
Effects of Corrective Helmet Therapy on Cervical Motion and Thermoregulation in Children With Positional Deformities
The purpose of the study is to examine how cranial helmet therapy may affect neck movement and body temperature regulation in children with positional head deformity.
- Trial name
- NCT07201324
- Testing
- cranial helmet therapy - observational
- Volunteers
- 270 people
- Sponsor
- Wroclaw University of Health and Sport Sciences