Clinical trials: Spine Osteoarthritis
Rheumatoid Arthritis, Systemic Lupus Erythematosus
Feasibility of an Immersive Virtual Reality Based Biofeedback Intervention for Outpatients in Rheumatology
The purpose is to study the use of virtual reality (VR) and biofeedback in rheumatology clinics to help manage chronic pain in patients with rheumatologic diseases.
- Conditions
- Rheumatoid Arthritis, Systemic Lupus Erythematosus, Spondyloarthropathy, Vasculitis
- Trial name
- NCT03459274
- Testing
- VR-Biofeedback
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cedars-Sinai Medical Center
Psoriatic Arthritis
Efficacy and Safety of Humira® in Patients With Psoriatic Arthritis in Normal Medical Practice
This study is a documentation of effectiveness and safety of Humira in patients with psoriatic arthritis.
- Trial name
- NCT01111240
- Where
- 509 sites in Germany
- Volunteers
- 4,635 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Spondylitis, Ankylosing
Remicade Safety Line (Ankylosing Spondylitis)(Study P03275)(COMPLETED)
This observational study is in line with the German educational plan with the aim to implement a tool to increase and monitor the awareness of tuberculosis screening and to reinforce the patient eligibility for a treatment with…
- Trial name
- NCT00818168
- Testing
- Infliximab
- Volunteers
- 320 people
- Sponsor
- Merck Sharp & Dohme LLC
Ankylosing Spondylitis
A Study to Evaluate the Efficacy and Safety of Bimekizumab in Subjects With Active Ankylosing Spondylitis
The purpose of the study is to demonstrate the efficacy, safety and tolerability of bimekizumab administered subcutaneously (sc) compared to placebo in the treatment of subjects with active ankylosing spondylitis (AS).
- Trial name
- BE MOBILE 2 (NCT03928743)
- Testing
- Bimekizumab
- Where
- 83 sites in United States, Belgium and 12 more
- Volunteers
- 332 people
- Sponsor
- UCB Biopharma SRL
Axial Spondyloarthritis
British Axial Spondyloarthritis Inception Cohort
The British Axial Spondyloarthritis Cohort (BAxSIC) study has been established under the auspices of the British Society for Spondyloarthritis (BRITSpA) in collaboration with the National Axial Spondyloarthritis Society (NASS) to…
- Trial name
- BAxSIC (NCT05676775)
- Testing
- No intervenetion
- Where
- United Kingdom
- Volunteers
- 500 people
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Ankylosing Spondylitis
Assessment of the Response to Etoricoxib in Patients With Ankylosing Spondylitis and Inadequate Response to ≥2 NSAIDs
The goal of this research is to assess the percentage of non-responders to ≥ 2 NSAIDs candidates a biological therapy that could adequately respond to treatment with etoricoxib This study confirm the result of a previous study in…
- Trial name
- NCT01091675
- Testing
- Etoricoxib
- Where
- 14 sites in Spain
- Volunteers
- 58 people
- Sponsor
- Spanish Foundation of Rheumatology
Psoriatic Arthritis (PsA)
Deucravacitinib-TNFi Combination Therapy for Difficult-to-Control Psoriatic Disease
The purpose of this research study is to determine the effectiveness of adding deucravacitinib to the participant's current Psoriatic Arthritis (PsA) treatment to see if it improves their symptoms and quality of life.
- Trial name
- COMBo (NCT07280702)
- Testing
- Deucravacitinib
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- University of Texas Southwestern Medical Center
Crohn Disease, Ulcerative Colitis
The Evaluation of Injection Site Pain and Adherence in Patients Switching From a Low To High Concentration Adalimumab (AVT-02) Across Multiple Indications.
The purpose of the Phase IV study is to investigate the effects of both Volume and Citrate on Injection Site Pain (ISP), adherence, patient satisfaction, Quality of Life, and Disease Assessment in the Canadian Adalimumab Market.
- Conditions
- Crohn Disease, Ulcerative Colitis, Rheumatoid Arthritis, Ankylosing Spondylitis
- Trial name
- EASE PAIN (NCT05913817)
- Testing
- AVT02 (Alvotech Biosimilar to Adalimumab)
- Where
- Canada
- Volunteers
- 324 people
- Sponsor
- Jamp Pharma Corporation
Axial Spondyloarthritis
Safety and Efficacy of Tofacitinib in the Treatment of NSAID Refractory Axial Spondyloarthritis:A Clinical Trial
Title Efficacy and Safety of Tofacitinib in the Treatment of NSAID-Refractory Axial Spondyloarthritis: A Clinical Trial Background: Axial spondyloarthritis (axSpA) is a chronic systemic inflammatory rheumatic disease affecting…
- Trial name
- NCT03738956
- Testing
- Tofacitinib
- Where
- Bangladesh
- Volunteers
- 30 people
- Sponsor
- Globe Pharmaceuticals Limited
Ankylosing Spondylitis (AS), Irisin
The Effect of Exercise on Serum Irisin Levels and Clinical Parameters in Patients With Axial Spondyloarthritis.
This study aimed to investigate the effects of high-intensity intermittent exercise and moderate-intensity continuous exercise on serum irisin levels, disease activity, functional status, and quality of life in patients with…
- Trial name
- NCT07327073
- Testing
- High-Intensity Interval Training, Moderate-Intensity Continuous Exercise, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Kirsehir Ahi Evran Universitesi
Axial Spondyloarthritis
Comparison of CT Scan Between Patients With Axial Spondyloarthritis and Control Subjects
The aim of this study is to define structural damage to the manubriosternal joint (MST) in axial spondyloarthritis (axSpA) by comparing its CT scan aspects between a population of patients with radiographic (axSpA) and a control…
- Trial name
- SPA-THORAX (NCT05779969)
- Testing
- Chest CT scan
- Where
- France
- Volunteers
- 377 people, healthy volunteers welcome
- Sponsor
- Hôpital NOVO
Arthritis, Rheumatoid, Arthritis, Psoriatic
Novel Complex Radiodiagnostics of Peripherial Arthropathies
Chronic peripherial arthritides are common diseases with soaring public health consequences. Our goal is to assess the role of photon-counting detector computed tomography in the diagnostics of peripherial arthropathies.
- Conditions
- Arthritis, Rheumatoid, Arthritis, Psoriatic, Crystal Arthropathies
- Trial name
- NCT05657847
- Testing
- Photon-counting detector-CT
- Where
- 3 sites in Hungary
- Volunteers
- 500 people
- Sponsor
- Semmelweis University
Psoriatic Arthritis
The Effect of n-3 Polyunsaturated Fatty Acids in Patients With Psoriatic Arthritis
Background: There is evidence for a high cardiovascular risk in rheumatic and inflammatory diseases . Recent evidence suggest that psoriatic arthritis is also associated with an increased cardiovascular risk with accelerated…
- Trial name
- NCT01818804
- Testing
- n-3PUFA, olive oil
- Where
- 2 sites in Denmark
- Volunteers
- 145 people
- Sponsor
- Aalborg University Hospital
Rheumatoid Arthritis, Psoriasis
A Study of Experimental Medication BMS-986251, Taken by Mouth, in Healthy Participants and Patients With Average to Very Serious Psoriasis
The purpose of this study is to investigate experimental medication BMS-986251 taken by mouth in healthy patients and patients with average to very serious Psoriasis (a condition characterized by itchy, dry skin with a scaly…
- Conditions
- Rheumatoid Arthritis, Psoriasis, Ankylosing Spondylitis, Inflammatory Bowel Diseases
- Trial name
- NCT03329885
- Testing
- BMS-986251
- Where
- Netherlands
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Arthritis, Psoriatic
Psoriatic Arthritis Pathobiology and Its Relationship With Clinical Disease Activity
The study aims to examine the relationship between synovial histopathology and change in clinical disease activity over time in a population of patients with psoriatic arthritis who have failed to respond to first-line treatment.
- Trial name
- PSABRE (NCT06676176)
- Where
- United Kingdom
- Volunteers
- 29 people
- Sponsor
- Barts & The London NHS Trust
Osteoarthritis, Rheumatoid Arthritis
Observational Study on Non-steroid Anti-inflammatory Drugs (NSAIDs) Treated Patients With Arthritic Disorder
The aim of this study is to find out how patients with osteoarthritis, rheumatoid arthritis and ankylosing spondylitis receiving NSAID-therapy are treated and managed by their doctor in usual clinical practice, how patients…
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Ankylosing Spondylitis
- Trial name
- EVIDENCE (NCT01176682)
- Where
- 244 sites in Belgium, France and 10 more
- Volunteers
- 1,149 people
- Sponsor
- AstraZeneca
Psoriasis, Psoriatic Arthritis
Prevention of Cardiovascular Disease and Mortality in Patients With Psoriasis or Psoriatic Arthritis
The goal of this research is to test a novel centralized care coordinator program to assist patients with psoriatic disease in lowering their risk of cardiovascular disease through the application of standard of care approaches…
- Conditions
- Psoriasis, Psoriatic Arthritis, Psoriatic Conditions, Cardiovascular Diseases
- Trial name
- CP3 (NCT05908240)
- Testing
- Care Coordinator Model
- Where
- 20 sites in United States
- Volunteers
- 603 people
- Sponsor
- University of Pennsylvania
Spondyloarthritis (SpA)
A Clinical Study to Evaluate the Efficacy of Biologics in SpA
Spondyloarthritis (SpA) is one of the potentially debilitating inflammatory diseases that affect the whole body, primarily burdening the sacroiliac joints and the spine. It mostly affects young and middle aged adults.
- Trial name
- NCT04399382
- Testing
- Biologics
- Where
- China
- Volunteers
- 40 people
- Sponsor
- The University of Hong Kong-Shenzhen Hospital
Arthritis, Psoriatic, Autoimmune Diseases
Genetic and Immune Studies of Rheumatoid Arthritis and Related Conditions
This protocol will examine blood, synovial fluid and synovial tissue from patients with rheumatoid arthritis and other chronic inflammatory joint diseases to study genetic and immunologic factors involved in the cause…
- Conditions
- Arthritis, Psoriatic, Autoimmune Diseases, Joint Diseases, Osteoarthritis
- Trial name
- NCT00001291
- Where
- United States
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Spondyloarthritis, Crohn Disease
Characterization of the Intestinal Microbiota in Patients With Inflammatory Bowel Disease and/or Spondyloarthritis and Study of the Impact of an Anti-TNF Alpha Therapy
Spondyloarthritis and inflammatory bowel diseases are common diseases, frequently met together in overlap syndromes. Their physiopathology remains puzzling.
- Conditions
- Spondyloarthritis, Crohn Disease, Ulcerative Colitis
- Trial name
- MIST (NCT03359642)
- Testing
- blood sample, stool samples, food questionnaire
- Where
- France
- Volunteers
- 23 people
- Sponsor
- University Hospital, Bordeaux
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