Clinical trials: Spine Osteoarthritis
Ankylosing Spondylitis
Program evaLuating the Autoimmune Disease iNvEstigational Drug cT-p13 in AS Patients(PLANETAS)
This study is the trial to demonstrate how our product is similar to remicade by comparing the results of blood samples in active Ankylosing Spondylitis patients.
- Trial name
- NCT01220518
- Testing
- Infliximab
- Where
- South Korea
- Volunteers
- 257 people
- Sponsor
- Celltrion
Psoriatic Arthritis
Differential Clinical and Serologic Response in Psoriasis and Psoriatic Arthritis to Drug Treatment
Psoriasis is a multifactorial cutaneous disorders which affects about 100000 patients in Taiwan. Psoriatic arthritis is also present in about 20~30 percents.
- Trial name
- NCT00451243
- Volunteers
- 20 people
- Sponsor
- National Taiwan University Hospital
Psoriatic Arthritis, Foot Arthritis
Effect of Custom Foot Orthoses in Patients With Psoriatic Arthritis
Foot involvement is a major concern in psoriatic arthritis (PsA). The patients could experience severe levels of foot pain and disability and reduced mobility and quality of life.
- Trial name
- NCT05075343
- Testing
- Custom foot orthoses
- Where
- 2 sites in Canada
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Patrick Boissy
Ankylosing Spondylitis
An Open-Label Multicentre Long-Term Extension Study of Etanercept for Ankylosing Spondylitis
This study is an extension trial of 0881A3-312-EU and is designed to provide information on the safety and efficacy of etanercept in patients with ankylosing spondylitis for up to 3 additional years.
- Trial name
- NCT00444340
- Testing
- Enbrel (Etanercept)
- Volunteers
- 70 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Axial Spondyloarthritis (AxSpA), Non-radiographic Evidence-AxSpA
A Multicenter, Postmarketing Study Evaluating the Concentration of Cimzia® in Mature Breast Milk of Lactating Mothers
The primary objectives of this study are to assess whether there is transfer of Certolizumab Pegol (CZP) into breast milk of lactating mothers who are receiving an established dosing regimen of CZP by evaluating the concentration…
- Conditions
- Axial Spondyloarthritis (AxSpA), Non-radiographic Evidence-AxSpA, Ankylosing Spondylitis, Crohn's Disease
- Trial name
- CRADLE (NCT02154425)
- Testing
- Breast milk sampling, Certolizumab Pegol
- Where
- 6 sites in United States, Netherlands and 1 more
- Volunteers
- 17 people
- Sponsor
- UCB BIOSCIENCES, Inc.
Plaque Psoriasis, Psoriatic Arthritis
Real-World Study of Xeligekimab for Moderate to Severe Plaque Psoriasis(XP-Real)
Xeligekimab Injection was approved in China on August 20, 2024, for treating adults with moderate to severe plaque psoriasis who are candidates for systemic treatment or phototherapy.
- Conditions
- Plaque Psoriasis, Psoriatic Arthritis, Scalp Psoriasis, Nail Psoriasis
- Trial name
- NCT06802848
- Testing
- Xeligekimab injection
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Chongqing Genrix Biopharmaceutical Co., Ltd
Axial Spondyloarthritis
The Effect of Exercise on Disease Activity and Cardiovascular Risk for Patients With Axial SpondyloArthritis
The overall aim of this multicenter randomised controlled trial (RCT) is to investigate if exercise can modify the disease course and prevent comorbidity in patient with spondyloarthritis (SpA).
- Trial name
- ESpA (NCT02356874)
- Testing
- Exercise
- Where
- 4 sites in Norway, Sweden
- Volunteers
- 100 people
- Sponsor
- Diakonhjemmet Hospital
Crohn Disease, Ulcerative Colitis
Expanded Access to Upadacitinib
This is an expanded access program (EAP) for eligible participants. This program is designed to provide access to upadacitinib prior to approval by the local regulatory agency. Availability will depend on territory eligibility.
- Conditions
- Crohn Disease, Ulcerative Colitis, Idiopathic Arthritis (Including sJIA, pJIA, or JPsA), Atopic Dermatitis
- Trial name
- NCT04159597
- Testing
- Upadacitinib
- Sponsor
- AbbVie
Spondyloarthritis
Study Evaluating the Effectiveness of Shiatsu on Fatigue in Patients With Axial Spondyloarthritis
Spondyloarthritis is a potentially serious disease with reduced life expectancy. Even if the clinical presentation is eminently variable from one patient to another, the most frequently encountered manifestations such as…
- Trial name
- SFASPA (NCT05433168)
- Testing
- SHIATSU, DUMMY SHIATSU
- Where
- France
- Volunteers
- 72 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Spondyloarthritis
Move Your Spondyl " Better Live Its Rheumatism With the Physical Activity "
By this project, the investigators are going to try to demonstrate that to use objects connected to make a physical activity can have an impact on the clinical activity of the disease by bringing the subjects which present a…
- Trial name
- NCT03458026
- Testing
- Connected object use combined with SMS (text messages) of physical activity reminders, Without connected object
- Where
- France
- Volunteers
- 108 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Psoriatic Arthritis
Efficacy at 24 Weeks and Long Term Safety, Tolerability and Efficacy up to 2 Years of Secukinumab (AIN457) in Patients With Active Psoriatic Arthritis (PsA)
This study will assess the efficacy and safety of secukinumab in patients with active psoriatic arthritis who are intolerant to or have had an inadequate response to NSAIDs, DMARDs and / or TNFα inhibitor therapy.
- Trial name
- FUTURE 1 (NCT01392326)
- Testing
- Secukinumab (75 mg), Secukinumab (150 mg)
- Where
- 110 sites in United States, Argentina and 17 more
- Volunteers
- 606 people
- Sponsor
- Novartis Pharmaceuticals
Ankylosing Spondylitis
Benefit of Adapted Physical Activity for Patients Suffering From Ankylosing Spondylitis
The current management of Spondylarthritis Ankylosant (SA), according to the recommendations of the HAS (High Authority of Health), must be a multidisciplinary global approach coordinated by the rheumatologist combining a…
- Trial name
- SPIKE (NCT04089774)
- Testing
- Adapted Physical Activity (APA)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Hospital St. Joseph, Marseille, France
Spondylitis, Ankylosing
Treat-to-Target Strategy With Etanercept for Ankylosing Spondylitis
Evaluate the disease activity guided tapering and discontinuation strategies of etanercept (ETN) in patients with ankylosing spondylitis (AS) in 48 weeks.
- Trial name
- T2TEAS (NCT03880968)
- Testing
- tapering or discontinuation of etanercept
- Volunteers
- 311 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Ankylosing Spondylitis
Etanercept (Enbrel) in Ankylosing Spondylitis
The study has the aim to investigate the efficacy and safety of etanercept in patients with active ankylosing spondylitis (AS) over 520 weeks.
- Trial name
- Enbrel_AS-2 (NCT01289743)
- Testing
- Etanercept
- Where
- 2 sites in Germany
- Volunteers
- 24 people
- Sponsor
- Charite University, Berlin, Germany
Axial Spondyloarthritis
A Study Treating Participants With Early Axial Spondyloarthritis (axSpA) Taking an Intense Treatment Approach Versus Routine Treatment
A study comparing a treat-to-target (T2T) intense treatment approach with routine treatment (Standard of Care [SOC]) in reducing disease activity in participants with axial spondyloarthritis (axSpA).
- Trial name
- STRIKE (NCT02897115)
- Testing
- Adalimumab, Non-steroidal Anti-inflammatory Drugs (NSAIDs)
- Volunteers
- 22 people
- Sponsor
- AbbVie
Axial Spondyloarthritis, Inflammatory Back Pain
Reliability of IBP Criteria & Activity Scores in Patients With AxSpA
The current ASAS classification of AxSpA relies either on sacroiliitis on imaging plus one SpA feature (imaging arm) or HLA-B27 antigen plus two SpA features (clinical arm), in a patient with chronic back pain and age at onset of…
- Trial name
- IBP/AxSpA (NCT05327140)
- Where
- Egypt
- Volunteers
- 206 people
- Sponsor
- Zagazig University
Intervertebral Disc Degeneration, Osteoarthritis, Spine
Open Access Database of Standing Full Body Radiographs in Asymptomatic Volunteers
A study of the skeletal structure and how the structure changes over time. The aim of the study is to evaluate the skeleton in 10 year increments to determine an understanding of the normal skeleton as a person ages.
- Trial name
- NCT03076658
- Testing
- EOS imaging
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Crohn Disease, Colitis, Ulcerative
A Long-term Extension Study of Ustekinumab in Pediatric Participants
The purpose of this study is to collect long-term safety data of subcutaneous (SC) ustekinumab
- Conditions
- Crohn Disease, Colitis, Ulcerative, Arthritis, Psoriatic
- Trial name
- UNITED (NCT05092269)
- Testing
- Ustekinumab
- Where
- 48 sites in United States, Argentina and 11 more
- Volunteers
- 159 people
- Sponsor
- Janssen Research & Development, LLC
Spondyloarthritis, Axial Spondyloarthritis
Characterizing Spondyloarthritis With 68Ga-FAPI PET/CT
To evaluate the potential usefulness of 68Ga-FAPI PET/CT for the diagnosis, inflammation evaluation and prognosis prediction in spondyloarthritis.
- Conditions
- Spondyloarthritis, Axial Spondyloarthritis, Ankylosing Spondylitis
- Trial name
- NCT05999643
- Testing
- Drug: 68Ga-FAPI
- Where
- China
- Volunteers
- 50 people
- Sponsor
- The First Affiliated Hospital of Xiamen University
Psoriatic Arthritis, Enthesitis
Ultrasound and Shear Wave Elastography Assessment of Entheses in Psoriatic Arthritis
Psoriatic arthritis (PsA) is a chronic inflammatory disease that frequently involves the entheses, where tendons, ligaments, and fascia insert into bone.
- Trial name
- SWE-PsA (NCT07785089)
- Testing
- Grayscale Ultrasonography, Power Doppler Ultrasonography, and Shear Wave Elastography
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Marmara University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.