Clinical trials: Spine Surgeries
Dysphagia, GERD
Whether Proton Pump Inhibitors, Administered Prior to or After Surgery, Can Reduce the Incidence and/or Severity of Difficulty Swallowing Foods and/or Liquids,Following Anterior Cervical Surgery
The researchers wish to investigate whether proton pump inhibitors, administered prior to or after surgery, can reduce the incidence and/or severity of difficulty swallowing foods and/or liquids,following anterior cervical…
- Conditions
- Dysphagia, GERD, Degenerative Joint Disease
- Trial name
- NCT03488147
- Testing
- Esomeprazole
- Where
- 2 sites in United States
- Sponsor
- Icahn School of Medicine at Mount Sinai
Pain, Postoperative, Spine Disease
Ultrasound Guided Modified Thoracolumbar Interfascial Plane Block for Spinal Surgery
Ultrasound guided thoracolumbar interfascial plane (TLIP) block was first described in 2015 by Hand et al. TLIP block involves injection of local anesthetics between multifidus and longissimus muscles at the third lumbar vertebra…
- Trial name
- TLIP (NCT03079076)
- Testing
- Bupivacaine, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ataturk University
Patients Undergoing Spine Surgery
Assessing the Accuracy of the RevK Sensor
Evaluation of a new generation of sensors for monitoring blood hemoglobin. The newest version is RevK.
- Trial name
- NCT01877876
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of California, San Francisco
Herniated Disk Lumbar
Lumbar Spine Surgery: Regional vs. General Anaesthesia
Background: Lumbar spine surgery can be performed using different anaesthetic techniques such as general endotracheal anaesthesia (GA) or spinal-based regional anaesthesia (RA), that have different side effect profiles (e.g.
- Trial name
- NCT03300089
- Testing
- General anaesthesia, Regional anaesthesia
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- St. Anna Clinic Luzern
Lumbar Spinal Stenosis, Spinal Instability
Flexion-Extension Radiograph Imaging Protocol Reliability Study
Orthopedic surgeons often face the dilemma of whether to add fusion to a decompression procedure of the spine. Their decision mainly relies on personal experience to determine if a level is unstable preoperatively or if a…
- Trial name
- NCT05633550
- Testing
- Flexion-extension radiographs
- Where
- 2 sites in Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rijnstate Hospital
Spine Diseases
Awakening in Spine Surgery: A Comparison Between Clinical Signs and Bispectral Index
BIS is one of several equipments used to monitor depth of anesthesia.Some studies found BIS can reduce total propofol dose when being used with target controlled infusion (TCI).The objective is to compare awakening time after…
- Trial name
- NCT02174913
- Testing
- bispectral index, Target controlled infusion of propofol, Fentanyl
- Where
- Thailand
- Volunteers
- 34 people
- Sponsor
- Mahidol University
Hoarseness
Incidence of Hoarseness After General Spine Surgery: Prospective Observational Study
Early diagnosis and appropriate treatment of hoarseness is known to improve quality of life and treatment outcomes. Therefore, appropriate research on the incidence of hoarseness after surgery is necessary.
- Trial name
- Hoarseness (NCT05996146)
- Where
- South Korea
- Volunteers
- 427 people
- Sponsor
- Seoul National University Hospital
Surgical Wound Infection, Spinal Deformity
Comparison of Antibiotic Protocols in Spine Patients With Postoperative Drains
In spine surgery, postoperative spinal drains are often utilized to prevent fluid buildup around the spinal cord. The purpose of this study is to determine whether postoperative antibiotic treatment continued for the duration of…
- Conditions
- Surgical Wound Infection, Spinal Deformity, Spinal Degeneration
- Trial name
- NCT01608854
- Testing
- Antibiotic Protocol
- Where
- United States
- Volunteers
- 539 people
- Sponsor
- NYU Langone Health
Auricular Acupressure, Cervical Spine Surgery
Auricular Acupressure on Improving Pain and Heart Variability in Patients After Cervical Spine Surgery
The primary objective of this study is to investigate the effectiveness of auricular acupressure in improving post-cervical spine surgery pain and heart rate variability in patients.
- Trial name
- NCT06087380
- Testing
- auricular acupressure, standard ward care
- Where
- Taiwan
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Lumbar Radiculopathy
Erector Spinae Block for Spine Surgery
This study is to determine whether or not the addition of liposomal bupivacaine in an ESP block will have long term benefits for patients undergoing lumbar spinal fusion surgery.
- Trial name
- NCT05417113
- Testing
- Liposomal bupivacaine, Bupivacaine
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Surgery
A Pilot Trial to Determine the Effective N-acetylcysteine Dose for Opioid Reduction for Spine Surgery.
Determine the optimal dose of IV N-acetylcysteine (NAC) to produce opioid reduction following spine surgery and estimate the difference in opioid consumption between placebo and the selected optimal dose.
- Trial name
- NCT04562597
- Testing
- Dose Response Curve N-acetylcysteine 50 mg/kg, Dose Response Curve N-acetylcysteine 100 mg/kg, Dose Response Curve N-acetylcysteine 150 mg/kg
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Pain
The Effect of Dexamethasone in Combination With Paracetamol and Ibuprofen on Postoperative Pain After Spine Surgery
The analgesic effect of dexamethasone is not well described, but studies have shown that dexamethasone can be a safe part of a multimodal analgesic strategy after surgery.
- Trial name
- NCT01953978
- Testing
- Dexamethasone, Morphine, Zofran
- Where
- Denmark
- Volunteers
- 160 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Pain, Postoperative, Spine Surgery
Randomized Trial of Intraoperative IV Versus Preoperative Oral Acetaminophen During Ambulatory Lumbar Discectomy
Effective non-opioid analgesics are of particular interest in ambulatory surgery, as providers may be able to reduce pain while avoiding perioperative opioids that can delay same day discharge.
- Trial name
- NCT04574778
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Rothman Institute Orthopaedics
Intraabdominal Hypertension, Prone Postion
Changes of Intra Abdominal Pressure During Surgeries in Prone Position as a Marker of Renal Damage
Background: Patients undergoing surgical operations in prone position do not have a measure of intra abdominal pressure as a standard procedure.
- Conditions
- Intraabdominal Hypertension, Prone Postion, Spine Surgery
- Trial name
- NCT05626868
- Testing
- Intra abdominal pressure measurement
- Where
- Poland
- Volunteers
- 24 people
- Sponsor
- Medical University of Warsaw
Analgesia, Lumbar Spine Disease
Ultrasound Guided Erector Spinae Block vs Thoracolumbar Interfascial Plane Block
Aim of this Study will be to compare Ultrasound guided erector spinae block vs thoracolumbar interfascial plane (TLIP) block in lumbar spine surgeries.
- Trial name
- NCT05596227
- Testing
- Propofol, Fentanyl, Rocuronium
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Tanta University
Spine Surgery, Telerehabilitation
Telerehabilitation After Spine Surgery
The goal of this randomized clinical trial is to assess how different methods of delivering post-operative instructions affect the participants' recovery after spinal decompression surgery.
- Conditions
- Spine Surgery, Telerehabilitation, Low Back Pain
- Trial name
- NCT07795697
- Testing
- Telerehabilitation method, Nurse instructions, Physiotherapy after surgery, personal
- Where
- Finland
- Volunteers
- 300 people
- Sponsor
- Kuopio University Hospital
Pain
Pharmacogenetic Morphine Spine Study
The purpose of this research study is to identify factors and genes (the DNA material that determines the makeup of the human body) that may be associated with how children cope with pain and respond to pain medication.
- Trial name
- NCT01839461
- Where
- United States
- Volunteers
- 137 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Enhanced Recovery After Surgery, Spine Surgery
Enhanced Recovery After Spine Surgery
Enhanced recovery pathways (ERP) after surgery have been shown to decrease length of stay and perioperative complications in a range of surgical specialties.
- Trial name
- NCT02949518
- Testing
- Enhanced Recovery Pathway (ERP) for Spine
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Quality of Life, Spinal Injuries
Establishing a Descriptive Cohort of Patients Cared for Operation on the Spine
This study aims to: 1. describe the monitoring of patients treated for spinal disorders. 2. create a comprehensive database of reliable and readily exploitable quickly to produce a library of cross publications between orthopedic…
- Conditions
- Quality of Life, Spinal Injuries, Spinal Diseases
- Trial name
- KEOPS (NCT02886260)
- Where
- France
- Volunteers
- 193 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Thoracic Spine Disorder
Ultrasound Localization in Thoracic Surgery - is Radiation Reduction Achievable?
The goal of this clinical trial is to see if the investigators can find a safer and quicker way to localize the correct spinal level before the start of thoracic spinal surgery.
- Trial name
- ULTRRA (NCT05968950)
- Testing
- Thoracic ultrasound
- Volunteers
- 20 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust