Clinical trials: Spine Surgeries
Multilevel Cervical Spinal Stenosis, Single Brachial Radiculopathy
Head-neck Coordination Analysis After Minimally Invasive Surgery in the Dorsal Cervical Spine
To proof patients' benefit of minimally invasive surgery in the dorsal cervical spine an apparatus to examine head-neck-coordination was constructed.
- Trial name
- MISDCS (NCT01988259)
- Testing
- Bilateral approach for Laminoplasty, Unilateral approach for laminoplasty, Subperiosteal approach for foraminotomy
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Schoen Klinik Hamburg Eilbek
Mean Blood Pressure
Phentolamine Versus Magnesium Sulphate Infusion During Elective Lumbar Spine Surgery: a Randomized Double Blind Comparative Study
The aim of this study is to evaluate the efficacy of controlled hypotensive anesthesia with phentolamine versus Magnesium sulfate in patients undergoing lumbar spine fusion surgery on blood loss, total dose of hypotensive agents…
- Trial name
- NCT04269980
- Testing
- MAP
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Scoliosis
Effect of Regional Anesthesia or Intravenous Infusion of Lidocaine on Morphine Use After Scoliosis Repair Surgery
The goal of the surgical correction of scoliosis is to prevent progression of the curve or progression of restrictive lung disease. After scoliosis surgery, patients experience severe pain.
- Trial name
- NCT06451562
- Testing
- Lidocaine
- Where
- Israel
- Volunteers
- 105 people
- Sponsor
- Assaf-Harofeh Medical Center
Spine Surgery
Incidence , Risk Factors and Outcomes of Haemodynamic Instability and Cardiac Arrest During Spine Surgery
Risk factors for cardiac arrest during spine surgery have been well defined, including lumbar fusion, age over 65 years, obesity, cardiovascular disease, ethnicity and ASA status.
- Trial name
- NCT05131854
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Zagazig University
Surgical Site Infection
The Use of Diluted Povidone Iodine Irrigation in Spine Surgery
The purpose of the study is to determine whether diluted Povidone Iodine solution used to irrigate surgical wounds during spine surgery decreases the incidence of surgical site infections.
- Trial name
- NCT01577524
- Testing
- Povidone-Iodine, Saline
- Where
- Canada
- Volunteers
- 58 people
- Sponsor
- Attabib, Najmedden, M.D.
Pedicle Screw Accuracy, Robot
Evaluation of the Accuracy of the eCential Robotics Robot in Spinal Surgery
Spinal surgery has evolved considerably over the years, and the introduction of advanced technologies has played a crucial role in improving clinical outcomes.
- Conditions
- Pedicle Screw Accuracy, Robot, Navigation, Spine
- Trial name
- Robotec Amiens (NCT07421752)
- Testing
- eCential Robotics solution
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Cervical Spondylosis, Cervical Radiculopathy
NuVasive® ACP System Study
The primary objective of this study is to evaluate the safety and performance of anterior cervical spine surgery using the NuVasive anterior cervical plate (ACP) System as measured by reported complications, radiographic…
- Conditions
- Cervical Spondylosis, Cervical Radiculopathy, Cervical Myelopathy, Cervical Disc Disease
- Trial name
- NCT05066711
- Where
- 3 sites in United States
- Volunteers
- 75 people
- Sponsor
- NuVasive
Stress
Intermediate Cervical Plexus Block on Stress Response
The aim of the present study is to investigate the effect of Bilateral Ultrasound-Guided intermediate cervical plexus Block combined with general anesthesia on the stress and inflammatory response in patients undergoing anterior…
- Trial name
- NCT06064214
- Testing
- u/s guided intermediate cervical plexus block
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Cairo University
Spine Surgery, Rotational Thrombo-elastometry (ROTEM)
Effectiveness of ROTEM-based Coagulation Surveillance on Reducing Blood Product Utilization During Complex Spine Surgery
The Purpose of this study is to identify added value of Rotational thrombo-elastometry (ROTEM) intra-operative coagulation surveillance on reducing blood product use during major reconstructive spine surgery.
- Trial name
- NCT02758184
- Testing
- ROTEM-based coagulation monitoring, Spine surgery
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Duke University
Anemia, Spine Surgery
Establishment of Optimal Transfusion Threshold During Spine Surgery
The purpose of this study is to determine whether a higher threshold for transfusion with red blood cells improves the tissue oxygenation.
- Trial name
- NCT00967109
- Testing
- Allowed drop in hemoglobin to level between 4,5-5,6 mmol/L, Allowed drop in hemoglobin to level between 5,6-6,5 mmol/L
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Single Level Stable Thoracolumbar Fracture Type AO A3, Multiple Level Stable Thoracolumbar Fracture Type AO A3
Spine FA3 - a Prospective, International, Multicenter Cohort Study on Treatment of of AO A3 Thoracolumbar Fractures
Thoracolumbar fractures are the most common spinal fractures with an average annual incidence between 18 and 30 per 100'000 inhabitants. The majority of these fractures are AO type A3 ("burst fractures").
- Trial name
- FA3 (NCT01751633)
- Testing
- Surgical, Conservative treatment
- Where
- 8 sites in Brazil, Chile and 4 more
- Volunteers
- 38 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Intraocular Pressure
Continuous Intraocular Pressure Patterns in Spine Surgery
Post-operative visual loss is a rare but serious complication after surgery. It is most significantly correlated with prone spinal surgery with a prolonged duration.
- Trial name
- NCT03299400
- Testing
- Contact lens sensor
- Where
- Hong Kong
- Volunteers
- 10 people
- Sponsor
- The University of Hong Kong
Lumbar Spinal Stenosis, Spinal Instability
Flexion-Extension Radiograph Imaging Protocol Reliability Study
Orthopedic surgeons often face the dilemma of whether to add fusion to a decompression procedure of the spine. Their decision mainly relies on personal experience to determine if a level is unstable preoperatively or if a…
- Trial name
- NCT05633550
- Testing
- Flexion-extension radiographs
- Where
- 2 sites in Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rijnstate Hospital
Spinal Column Tumor
Primary Tumor Research and Outcomes Network
This project aims to establish a network of spine oncology centers dedicated to prospective multicenter research of patients diagnosed with a primary tumor of the spine and will include a comprehensive prospective clinical…
- Trial name
- PTRON (NCT02790983)
- Where
- 19 sites in United States, Australia and 7 more
- Volunteers
- 1,350 people
- Sponsor
- AO Innovation Translation Center
Lumbar Spine Surgery, Hemodynamic Changes
IVC Collapsibility Index in Lumbar Stabilization Surgery
This study aims to evaluate perioperative hemodynamic changes using the inferior vena cava (IVC) collapsibility index in patients undergoing lumbar stabilization surgery under general anesthesia.
- Conditions
- Lumbar Spine Surgery, Hemodynamic Changes, Intravascular Volume Status
- Trial name
- NCT07549165
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Trabzon Kanuni Education and Research Hospital
Pain, Postoperative
Safety and Efficacy Study of Fentanyl Iontophoretic Transdermal System (ITS) for Management of Moderate to Severe Acute Pain in Participants Who Have Undergone Elective Spine or Orthopedic Surgery
The purpose of this study is to evaluate in daily clinical practice the safety and efficacy of fentanyl Iontophoretic Transdermal (through the skin) System (ITS) for management of moderate (medium level of seriousness) to severe…
- Trial name
- NCT00779038
- Testing
- Fentanyl ITS
- Where
- 3 sites in Belgium
- Volunteers
- 13 people
- Sponsor
- Janssen Cilag N.V./S.A.
CerebroSpinal Fluid (CSF) Leak, Dural Tear
A Prospective, Randomized, Two-Arm, Controlled, Single-Blind, Multi-Center Study to Evaluate the Safety and Efficacy of ArtiFix® Dural Repair Sealant Graft in Cranial and Spine Surgery (NEOFIX Study)
The purpose of the NEOFIX study is to evaluate the safety and efficacy of ArtiFix® dural sealant graft in comparison to usual treatment for Dural repair (membrane that covers the brain and spinal cord) following cranial and spine…
- Trial name
- NEOFIX (NCT07765862)
- Testing
- ArtiFix® is a surgical dural sealant graft intended to close dural defects following cranial and spine surgeries., Standard of Care (Investigator Choice)
- Volunteers
- 228 people
- Sponsor
- Nurami Medical Ltd
Fluid Management During Elective Spine Surgeries
Conventional Fluid Management vs Plethysmographic Variability Index -Based Goal Directed Fluid Management
Plethysmographic variability index is a dynamic method for evaluation of volume status which depends on estimation of respiratory variations in pulse oximeter waveform amplitude.
- Trial name
- NCT05239286
- Testing
- General anaesthesia, Conventional fluid managment, PVI dependant goal directed fluid therapy
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Cairo University
Scoliosis Idiopathic
PMCF (Post-Market Clinical Follow-up) Study on The Tether™ in UK (United Kingdom)
The goal of this observational study is to collect information about The Tether™ device in participants with progressive idiopathic scoliosis, Lenke Type 1 curves.
- Trial name
- NCT05830825
- Testing
- Vertebral Body Tethering (VBT)
- Where
- 3 sites in United Kingdom
- Volunteers
- 100 people
- Sponsor
- LDR Médical SAS
Pain, Postoperative, Opioid Use
The Effect of Perioperative Intravenous Lidocaine Infusion on Opioid Consumption After Lumbar Spine Surgery
The purpose of this study is to determine whether an infusion of lidocaine during surgery can reduce the need for postoperative opioid pain medication use in patients undergoing lumbar spine surgery.
- Trial name
- NCT03624985
- Testing
- Intravenous Lidocaine Infusion
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- University of Vermont Medical Center