Clinical trials: Spine Surgeries
ERAS
Effect of Regional Anesthesia on Enhanced Recovery After Spine Surgeries
This study will be carried out on 80 patients who will be presented for different spine surgeries under general anesthesia and regional anesthesia technique in Tanta university hospitals.
- Trial name
- NCT04586257
- Testing
- Erector spinae plane block, Throacolumbar interfacial plane block
- Where
- Egypt
- Volunteers
- 93 people
- Sponsor
- Tanta University
Rib Fracture, Postoperative Pain
SPSIP vs ESP Block for Analgesia After Rib Fracture Surgery
This randomized clinical trial aims to evaluate and compare the analgesic efficacy of the Serratus Posterior Superior Intercostal Plane (SPSIP) block and the Erector Spinae Plane (ESP) block in patients undergoing surgical…
- Conditions
- Rib Fracture, Postoperative Pain, Thoracic Trauma
- Trial name
- NCT07553208
- Testing
- Erector Spinae Plane Block (ESP), Serratus Posterior Superior Intercostal Plane (SPSIP)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Antalya City Hospital
Brain Surgery With Motor Evoked Potential Monitoring, Spine Surgery With Motor Evoked Potential Monitoring
Strategy for Maintaining Partial Neuromuscular Blocking Adequate for Motor Evoked Potential During Neurosurgery
The maintenance of partial neuromuscular blocking during general anesthesia for neurosurgery is essential for intraoperative motor-evoked potential monitoring.
- Trial name
- NCT01388868
- Testing
- TOF count guided adjustment, T1/ T0 guided adjustment, T2/ T0 guided adjustment
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Samsung Medical Center
Intervertebral Disc Degeneration
Duloxetine as an Analgesic Agent in Patients Undergoing Elective Spine Surgery
Duloxetine as an analgesic agent in patients undergoing elective spine surgery: evaluation with fentanyl demand controlled by the patient.
- Trial name
- Duloxetine (NCT02535000)
- Testing
- Duloxetine
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Serviço de Anestesiologia de Joinville
Spinal Deformity, Paediatric Surgery, Tranexamic Acid
Topical Tranexamic Acid in Major Paediatric Spine Deformity Surgery: A Randomized Controlled Trial
Our study will evaluate the use of topical and intravenous (IV) Tranexamic Acid (TXA) in spine surgery. The purpose of TXA is to prevent clotting during surgery to reduce blood loss.
- Trial name
- NCT02093988
- Testing
- Topical TXA, Intravenous TXA
- Where
- Canada
- Volunteers
- 160 people
- Sponsor
- University of British Columbia
Vertebral Fracture
Identification of Microcirculation and Inflammation After Posterior Stabilization of the Spine
In this project, with unstable vertebral fractures, the microcirculation of the skin and muscle (O2C,Laser-Doppler/White-light -Spectroscopy and contrast-enhanced sonography) will be evaluated in both conventional and in…
- Trial name
- MicroSpine (NCT01266200)
- Testing
- Mantis, XIA
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- RWTH Aachen University
Degenerative Diseases, Nervous System
Performance Assessment Of The PMD-200 In Subjects With Degenerative Lumbar Spine Disease Who Requires Surgical Procedure
Performance assessment of the PMD-200, a novel pain monitor, in subjects with degenerative lumbar spine disease who requires surgical procedure
- Trial name
- NCT03389048
- Testing
- PMD-200, SLR
- Where
- Israel
- Volunteers
- 21 people
- Sponsor
- Medasense Biometrics Ltd
Wound Heal
Platysma Incision Cosmesis
The anterior cervical fusion and decompression (ACDF) surgery provides direct access to symptomatic areas of the cervical spine.
- Trial name
- NCT03338608
- Testing
- Anterior Cervical Decompression and Fusion, Vertical Platysma Incision, Transverse Platysma Incision
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Boston Medical Center
Spinal Diseases
Pilot Study to Evaluate Feasibility of DensiProbe Spine Assessing Bone Strength in Spinal Surgery
A new mechanical device was developed in order to provide the surgeon with intraoperative information about the mechanical strength of the cancellous bone within the vertebral body.
- Trial name
- DensiProbe (NCT01126385)
- Testing
- DensiProbe Spine
- Where
- 2 sites in Switzerland
- Volunteers
- 30 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Degenerative Lumbar Spinal Stenosis, Degenerative Disc Disease
Effect of Pre-existing Adjacent Segment Degeneration on Long-term Effectiveness After Lumbar Fusion Surgery
This is a prospective single-center study. Patients requiring posterior lumbar interbody fusion (PLIF) for lumbar degenerative disease are prospectively enrolled and followed.
- Conditions
- Degenerative Lumbar Spinal Stenosis, Degenerative Disc Disease, Degeneration Spine
- Trial name
- NCT04467944
- Testing
- Pre-existing degenerative factors at adjacent segment
- Where
- China
- Volunteers
- 210 people
- Sponsor
- Peking University Third Hospital
Dysphagia, Cervical Spinal Cord Injury
Dysphagia After Anterior Cervical Spine Surgery
The purpose of this research project is to investigate the incidence of impaired swallowing (dysphagia) after anterior cervical spine surgery (ACSS) and to study the long-term effect of dysphagia on nutritional status 12 ± 3…
- Trial name
- NCT04855838
- Testing
- Oral neuromuscular training
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Umeå University
Medium-/Long-segment Spinal Fusion Patients, Spine Surgeons
Evaluation of an Online Peri-operative Health Education Platform for Patients Undergoing Spine Surgery: Ready Set Recover
Chronic back pain is the world's leading cause of disability, with spine surgery being a common yet costly intervention. However, many patients experience suboptimal recovery, with persistent pain and functional limitations…
- Conditions
- Medium-/Long-segment Spinal Fusion Patients, Spine Surgeons, Chronic Low Back Pain, Scoliosis Patients
- Trial name
- NCT07766824
- Testing
- Ready Set Recover
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National University of Natural Medicine
Low Back Pain
Comparing Analgesia for Postoperative Pain Relief in Spine Surgery
The study will involve adult patients undergoing elective thoracolumbar-sacral spine surgery involving 1-5 spine levels, at the Brigham and Women's hospital that have an anticipated post surgical hospital stay of one to three…
- Trial name
- NCT02968862
- Testing
- observational
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Spinal Diseases
Observational Clinical Study to Plan, Position and Check Instrument Placement for Spine Surgery Interventions
There is a clear need in spine surgery to place pedicle screws in the right place in the spine with good accuracy to avoid damage to important structures (spinal cord, nerve roots or vertebral arteries).
- Trial name
- NCT03015142
- Testing
- New image-guidance software
- Where
- Sweden
- Volunteers
- 21 people
- Sponsor
- Philips Clinical & Medical Affairs Global
Spinal Surgery, Lidocaine
Effect of Perioperative Lidocaine on Gastrointestinal Function Recovery After Lumbar Spine Surgery in Adults
Spinal surgery often involves multiple segments. The trauma of surgery is large, the duration of postoperative pain is long, and the pain is severe. Therefore, the use of opioids in perioperative period is large.
- Conditions
- Spinal Surgery, Lidocaine, Pain, Opioid Consumption
- Trial name
- NCT04922359
- Testing
- Lidocain, normal saline
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Peking University People's Hospital
Discectomy, Vertebral Fractures
Comparative Study Between ESPB Versus IV Morphine as Postoperative Analgesia After Spine Surgeries .
Postoperative pain is often severe in patients undergoing lumbar surgery. Due to postoperative pain, patients are unwilling to get out of bed at an early stage, which affects their recovery.
- Trial name
- NCT05350696
- Testing
- Erector Spinae plane block (plain pubivicaine), Intravenous morphine group
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University
Lumbar Spine Degenerative Changes
Increasing Long-Term Physical Activity After Lumbar Spine Surgery
After recuperating from low back surgery patients often perpetuate a sedentary lifestyle because they are concerned about injury and recurrent pain.
- Trial name
- NCT02611427
- Testing
- Education/Self-efficacy, Education
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- Hospital for Special Surgery, New York
Cervical Spine Fractures
MALMOS Technique for Selected Subaxial Cervical Spine Fractures
This prospective study will evaluate the clinical and radiological outcomes of the MALMOS technique with neutralization H-plate fixation in patients with selected subaxial cervical spine fractures.
- Trial name
- MALMOS (NCT07905573)
- Testing
- Meshtawy's Anterior Ligamentotaxis and Miniplate Osteosynthesis (MALMOS) Technique With Neutralization H-Plate Fixation
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Assiut University
Pain
Effect of Perioperative Intravenous Lidocaine on Postoperative Quality of Recovery in Patients Undergoing Spine Surgery
Acute postoperative pain is an unpleasant, unwanted sensory and emotional experience for the patient. The investigators seek to determine if the addition of systemic lidocaine can improve the quality of recovery after spine…
- Trial name
- NCT01930877
- Testing
- Lidocaine
- Where
- United States
- Sponsor
- Baylor College of Medicine
Progressive Scoliosis
Surgical Treatment of Progressive Scoliosis With "NEMOST" Growing Rod
The purpose of this study is to evaluate the performance of the device "NEMOST" on maintaining of the correction of the scoliosis with growth preservation and avoiding iterative surgeries.
- Trial name
- NEMOST (NCT02266667)
- Testing
- 2 NEMOST rods : bilateral vertebral-pelvic implantation, 1 NEMOST rod :unilateral vertebral-pelvic implantation
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris