Clinical trials: Spine Surgery, open to volunteers
The Lumbar Spine Surgical Intervention, Arthrodesis
Evaluation of the Effect of Reiki on Pain After Lumbar Surgery
The goal of this clinical trial (prospective, comparative, and randomized double-blind study) is to learn if Reiki (a non-pharmacological intervention), when used alongside standard care, can treat and reduce postoperative pain…
- Conditions
- The Lumbar Spine Surgical Intervention, Arthrodesis, Severe Herniated Disc, Scoliosis
- Trial name
- REDAL (NCT07722117)
- Testing
- Reiki treatment and chirurgy
- Where
- 2 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Clinique Bizet
Spine, Pain
Effect of Magnesium on Neuromonitoring
Intraoperative neurophysiologic monitoring (IONM) is commonly used during complex spinal surgery to monitor the integrity of neural structures and improve the perioperative safety profile.
- Conditions
- Spine, Pain, Spine Surgery, Spine Surgery With Neuromonitoring
- Trial name
- MgNm (NCT06975072)
- Testing
- Magnesium sulfate administration
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, San Francisco
Opoid Managment, Pain Management
Effect of Opioid-Sparing Anesthesia on Postoperative Opioid Consumption and Pain in Elderly Patients Undergoing Spine Surgery
The goal of this clinical trial is to learn if an anesthesia management strategy called opioid-sparing anesthesia could help reduce postoperative opioid consumption, pain intensity and enhance recovery in elderly patients…
- Trial name
- NCT07588802
- Testing
- Opioid-Sparing Protocol, Routine anesthesia protocol
- Volunteers
- 120 people
- Sponsor
- Massachusetts General Hospital
Chronic SSRI/SNRI Use and Intraoperative Propofol Requirements
The Effect of Chronic ssrı/snrı Antidepressant Treatment on Propofol Consumption in Elective Spine Surgery
The goal of this observational study is to learn whether long-term use of selective serotonin reuptake inhibitor (SSRI) or serotonin-norepinephrine reuptake inhibitor (SNRI) antidepressants is related to the amount of propofol…
- Trial name
- NCT07822295
- Where
- Turkey (Türkiye)
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Kocaeli City Hospital
Symptom Duration, Outcomes
Affection of Symptoms Duration on Outcomes of Lumbar Spine Surgery
This study aims to evaluate the affection of symptoms duration on outcomes of lumbar spine surgery.
- Conditions
- Symptom Duration, Outcomes, Lumbar Spine Surgery
- Trial name
- NCT07061067
- Testing
- Lumbar Spine Surgery
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kafrelsheikh University
Spine Surgery Complications, Infection
Surgical Recovery Support Pillow for Spine Surgeries
The present study investigates the feasibility of a support pillow for use after spinal surgical procedures, and more particularly, to protect the midline region of the back following spinal surgery.
- Trial name
- NCT07720856
- Testing
- Surgical Recovery Support Pillow
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Spinal Fusion
Endothelial Damage in Major Spine Surgery, Measured by Circulating Syndecan-1: an Observational Study.(GlycOrtho)
The goal of this observational study is to learn about endothelial damage in major spine surgery, expressed as rise in circulating Syndecan-1.
- Trial name
- GlycOrtho (NCT06119542)
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Istituto Ortopedico Rizzoli
Radius; Deformity, Hip Osteoarthritis
Clinical Evaluation and Cost-effectiveness Analysis of 3D Digital Surgery in Traumatology
Digital surgery, in combination with patient specific instrumentation (PSI) is being used more and more in traumatology due to its proven benefits and applications.
- Conditions
- Radius; Deformity, Hip Osteoarthritis, Hip Arthritis, Hip Arthropathy
- Trial name
- NCT06603831
- Testing
- patients treated using 3D technology and Patient-Specific Instrumentation, Patients treated with conventional surgery, without using 3D technology
- Where
- Spain
- Volunteers
- 180 people
- Sponsor
- Corporacion Parc Tauli
Surgical Education
Patient Specific Virtual Reality for Simulation of Spine Procedures: an Intelligent Image Segmentation, Registration and 3-dimensional Visualization in a Unified Virtual Reality Workflow for Image Guided Therapy, and Education - Physician Testing
The goal of this clinical trial is to learn if patient specific virtual reality (VR) simulations can be used for surgical orthopaedic education in resident and fellow physician populations.
- Trial name
- NCT06714539
- Testing
- Patient Specific Virtual Reality Stimulation
- Volunteers
- 13 people
- Sponsor
- Sunnybrook Health Sciences Centre
Spinal Deformity, Bone Graft
Prospective i-FactorTM Analysis Fusion Rate and Quality of Life
Adult spinal deformity surgery is a complex procedure that involves many risks and complications. Bone grafts and bone substitutes are essential to achieve fusion and manage stability in spinal surgery.
- Conditions
- Spinal Deformity, Bone Graft, Fusion Rate, Quality of Life
- Trial name
- NCT04610021
- Testing
- i-FactorTM Bone graft
- Where
- Spain
- Volunteers
- 128 people
- Sponsor
- Complejo Asistencial Universitario de León Urgencias
Pain After Surgery
RISS Versus Lower Thoracic ESP Block for Analgesia After Laparoscopic Abdominal Surgery: A Randomized Trial
The goal of this clinical trial is to investigate the analgesic efficacy of ultrasound-guided Romboid Intercostal and Subserratus (RISS) block versus lower thoracic Erector Spinae Plane (ESP) block after laparoscopic abdominal…
- Trial name
- NCT07593300
- Testing
- Group A (n=35): Ultrasound-guided RISS block (RISS):, Group B (n=35): Ultrasound-guided lower thoracic ESP block
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Misr University for Science and Technology
Spine Surgery
SpinePal Open Pilot
SpinePal is a self-guided digital intervention developed for patients undergoing spine surgery. The goal of this study is to learn if SpinePal is acceptable to people undergoing spine surgery.
- Trial name
- NCT07737912
- Testing
- SpinePal
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Trustees of Dartmouth College
Spinal Diseases, Endoscopy Simulation
Comparing 3D and 2D Views in Biportal Spine Surgery: A Pilot Simulation Study
This study aims to compare three-dimensional (3D) and two-dimensional (2D) visualization in biportal endoscopic spine surgery using a simulated environment.
- Conditions
- Spinal Diseases, Endoscopy Simulation, Lumbar Vertebrae, Randomized Controlled Trial
- Trial name
- NCT07171801
- Testing
- Three-Dimensional Endoscopic Visualization, Two-Dimensional Endoscopic Visualization
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Felix Corr
Discogenic Low Back Pain, Intervertebral Disc Degeneration
RenewDisc Trial: Endoscopic Discectomy and Autologous Stem Cell Therapy for Discogenic Low Back Pain
he RenewDisc Trial is a prospective observational clinical study evaluating outcomes in patients with confirmed discogenic low back pain who undergo standard clinical care using endoscopic spine procedures.
- Conditions
- Discogenic Low Back Pain, Intervertebral Disc Degeneration, Lumbar Disc Disease, Chronic Low Back Pain
- Trial name
- RENEWDISC (NCT07338877)
- Where
- Slovakia
- Volunteers
- 120 people
- Sponsor
- EPC Education s.r.o.
Postoperative Pain, Chronic Postsurgical Pain
Erector Spinae Plane Block for Chronic Pain After Spinal Surgery
The aim of this study is to evaluate whether the erector spinae plane (ESP) block reduces acute and chronic postoperative pain in patients undergoing spinal surgery.
- Conditions
- Postoperative Pain, Chronic Postsurgical Pain, Spinal Surgery
- Trial name
- NCT07834502
- Testing
- NRS SCORE, Total tramadol consumption, Post Operative Pain Relievers
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Aydin Adnan Menderes University
Hypopharyngeal Pressure Changes Between Before and After Swallowing Rehabiliation
Enhancing Early Swallowing Recovery in Older Dysphagic Patients Afetr Anterior Cervical Spine Surgery
The early swallowing rehabilitation program in older patients receiving elective surgery is regarded to enhance the recovery pf swallowing ability.
- Trial name
- NCT05494515
- Testing
- the early swallowing rehabilitation program
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Post Operative Pain, Spinal Surgery
Methadone to Reduce Chronic Opioid Use After Major Spine Surgery: The MEND Pilot Feasibility Study
The investigators propose a randomized, triple-blinded (patients, investigators, outcomes assessors), placebo-controlled pilot feasibility trial (Methadone to End Narcotic Dependence, MEND trial) to assess the feasibility and…
- Trial name
- MEND (NCT07222072)
- Testing
- Methadone
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Wound Closure, Brain Tumor Adult
Evaluation of the Efficacy of STRATAFIX for Neurosurgical Cranial and Spine Procedures
This research is studying a device already approved by the Food and Drug Administration (FDA) to treat wound closures. Researchers are studying a large group of people to continue to learn information about the safety of the…
- Conditions
- Wound Closure, Brain Tumor Adult, Spine, Neurovascular
- Trial name
- NCT07225101
- Testing
- STRATAFIX PDS and Monocryl suture
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- University of Michigan
Venous Thromboembolism (VTE), Deep Vein Thrombosis (DVT)
Extended Prophylactic Anticoagulation Following Spinal Surgery for Metastatic Disease
People who have surgery on their spine to treat cancer that has spread (metastatic disease) have a high chance of developing dangerous blood clots in the legs or lungs.
- Conditions
- Venous Thromboembolism (VTE), Deep Vein Thrombosis (DVT), Pulmonary Embolism (PE), Spine Metastasis
- Trial name
- NCT07713875
- Testing
- Apixaban
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- James Bayley
Degenerative Disc Disease, Degenerative Spondylolisthesis
Lumbar Interbody Implant Study
The objective of this study is to evaluate the safety and performance of NuVasive interbody implants when used during thoracic and/or lumbar spine surgery as measured by reported complications, radiographic outcomes, and…
- Conditions
- Degenerative Disc Disease, Degenerative Spondylolisthesis, Degenerative Scoliosis, Spinal Stenosis
- Trial name
- NCT04418830
- Where
- 16 sites in United States
- Volunteers
- 1,050 people
- Sponsor
- NuVasive