Clinical trials: Spirometry, open to volunteers
Rib Fractures, Spirometry
Breathing Exercise for Rib Fracture
Respiratory physiotherapy is routinely performed after thoracic surgery operations to increase lung expansion and prevent pulmonary complications such as atelectasis and pneumonia.
- Trial name
- NCT06222333
- Testing
- Respiratory physiotherapy, Conservative Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Kastamonu University
Chronic Thromboembolic Pulmonary Hypertension, Physical Disability
Frailty, Physical Capacity and Lung Function in Postoperative Pulmonary Endarterectomy Patients
The goal of this observational and prospective study is to investigate changes in physical performance, lung function, respiratory and peripheral muscle strength in patients during the postoperative period following pulmonary…
- Conditions
- Chronic Thromboembolic Pulmonary Hypertension, Physical Disability, Fragility
- Trial name
- NCT06286891
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- University of Sao Paulo General Hospital
Common Variable Immunodeficiency
Usage of Spirometry in Managing IgG Therapy in CVID With Airway Disease
Although there is evidence in the literature that gammaglobulin replacement therapy can lead to a reduction in the prevalence of pulmonary infection and improved lung function, there is no published study to guide immunologists…
- Trial name
- NCT05193552
- Testing
- Hizentra
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Congenital Heart Disease (CHD), Postoperative Respiratory Dysfunction
Effect of Coughing Exercises Versus Incentive Spirometry on Respiratory Function and Recovery in Children After Cardiac Surgery.
This study examines the effects of coughing exercises and incentive spirometry (IS) on lung function and recovery in children who undergo heart surgery.
- Conditions
- Congenital Heart Disease (CHD), Postoperative Respiratory Dysfunction, Postoperative Recovery After Cardiac Surgery
- Trial name
- CEXIS (NCT07405333)
- Testing
- Coughing Exercises, Incentive Spirometry, Standard Postoperative Care
- Where
- 4 sites in Iraq
- Volunteers
- 99 people
- Sponsor
- University of Baghdad
Preserved Ratio Impaired Spirometry (PRISM)
An Exploratory Study on Triple Inhaler Therapy in Patients With Early Lung Function Impairment
Preserved Ratio Impaired Spirometry (PRISm) is characterized by a normal forced expiratory volume in one second (FEV1)/forced vital capacity (FVC) ratio but an FEV1 below 80% of the predicted value.
- Trial name
- BGF-PRISm (NCT07595796)
- Testing
- Budesonide/glycopyrronium bromide/formoterol inhalation aerosol
- Volunteers
- 23 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Asthma, Pulmonary Function
Vitamin C to Decrease Effects of Smoking in Pregnancy on Infant Lung Function (VCSIP) Longer Term Follow Up
The overall aims of this protocol are to determine whether prenatal supplementation with vitamin C to pregnant smokers can improve pulmonary function at 10 years of age in their offspring.
- Conditions
- Asthma, Pulmonary Function, Wheezing, In Utero Nicotine
- Trial name
- VCSIP (NCT06106646)
- Testing
- No active intervention in this protocol (previously randomized to Vitamin C)
- Where
- 2 sites in United States
- Volunteers
- 225 people
- Sponsor
- Oregon Health and Science University
Preserved Ratio Impaired Spirometry
Bufei Recipe Reduces the Incidence Rate of COPD
Establish early TCM prevention and treatment program to reduce the incidence rate of COPD.
- Trial name
- NCT06375824
- Testing
- Bufei Recipe
- Volunteers
- 1,100 people
- Sponsor
- Henan University of Traditional Chinese Medicine
Bronchial Asthma, Vitamin D Deficiency
Vitamin D Status and Asthma Control, Pulmonary Function, and Oxidative Stress in Adults With Bronchial Asthma
Asthma is a chronic inflammatory airway disease associated with variable airflow limitation and persistent respiratory symptoms.
- Conditions
- Bronchial Asthma, Vitamin D Deficiency, Pulmonary Function Impairment, Oxidative Stress
- Trial name
- VD-ASTHMA (NCT07733635)
- Volunteers
- 134 people
- Sponsor
- Sinai University
Lung Diseases
American Lung Association (ALA) Lung Health Cohort
The ALA-LHC is a longitudinal, multi-center cohort study that will enroll approximately 4,000 young adults between the ages of 25-35 who do not have severe lung disease.
- Trial name
- NCT04543461
- Where
- 37 sites in United States
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Chronic Obstructive Pulmonary Disease, Pulmonary Hypertension
Breathe Easier With Tadalafil Therapy for Dyspnea in COPD-PH
The investigators will study whether the drug tadalafil improves shortness of breath in 126 Veterans with Chronic Obstructive Pulmonary Disease (COPD) and high blood pressure in the lungs.
- Conditions
- Chronic Obstructive Pulmonary Disease, Pulmonary Hypertension, Dyspnea
- Trial name
- BETTER COPD-PH (NCT05937854)
- Testing
- Tadalafil
- Where
- 5 sites in United States
- Volunteers
- 126 people
- Sponsor
- VA Office of Research and Development
Chronic Obstructive Pulmonary Disease (COPD), Asthma
Mitigating Chronic Respiratory Disease Through the Lens of Multimorbidity (MARES3)
The investigators aim to investigate how individuals attending primary healthcare (PHC) services in Brazil for treatment of non-communicable diseases (NCDs), identified there as having abnormal spirometry or as being at high risk…
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Asthma, Preserved Ratio Impaired Spirometry (PRISM)
- Trial name
- NCT07134855
- Where
- 2 sites in Brazil
- Volunteers
- 473 people
- Sponsor
- University College, London
Postoperative Pulmonary Complications, Atelectasis
The Effect of the 5T Teach-Back Method on Respiratory Exercise and Incentive Spirometer Training
Breathing problems after surgery are common and can lead to serious complications such as low oxygen levels, lung collapse, or pulmonary embolism.
- Conditions
- Postoperative Pulmonary Complications, Atelectasis, Patient Education, Respiratory Exercises
- Trial name
- TEACH-BREATHE (NCT07350616)
- Testing
- 5T Teach-Back-Based Respiratory Exercise and Incentive Spirometer Education, Standard Verbal Respiratory Education
- Volunteers
- 76 people
- Sponsor
- Suleyman Demirel University
Chest Wall Deformity, Prominent Lower Rib Cage
Prospective Evaluation of Anterior Aesthetic Rib Cage Remodeling With Osteosynthesis for Lower Anterior Thoracic Prominence
This prospective single-group study will evaluate anterior aesthetic rib cage remodeling with osteosynthesis (ARCO) in adults with anteroinferior rib prominence or deformity.
- Trial name
- NCT07813234
- Testing
- Anterior Aesthetic Rib Cage Remodeling With Osteosynthesis, Chest CT and Spirometry Follow-up
- Where
- Colombia
- Volunteers
- 160 people
- Sponsor
- Research Inc
Chronic Obstructive Pulmonary Disease (COPD), Preserved Ratio Impaired Spirometry (PRISM)
Comparison of Clinical Status of Individuals With COPD and Preserved Ratio Impaired Spirometry
Despite the globally varying high prevalence rate of the PRISm phenotype, there are no guidelines for its diagnostic evaluation and management.
- Trial name
- NCT06682832
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Hacettepe University