Clinical trials: Split Thickness Skin Graft
Surgical Wound
Single-Use Negative Pressure Wound Therapy for Free Flap Donor Sites
Various management options for free flap donor sites that require split thickness skin grafting exist. None has proven superior from both a patient care and a cost standpoint.
- Trial name
- NCT03340025
- Testing
- PICO Single Use Negative Pressure Wound Therapy System, xeroform gauze
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Alabama at Birmingham
Wound Healing
Manuka Honey for Wound Care
Since antiquity, honey has been recognized for its healing properties. Literature about the use of medicinal honey for wound care dates back centuries with recent data suggesting its use in patients suffering from burns or…
- Trial name
- NCT02259491
- Testing
- Manuka Honey Dressing
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Reconstruction
The Comparison of Thick Split-thickness Skin Graft Versus Thin Split-thickness Skin Graft
In clinical settings, split-thickness skin graft (STSG) remain the gold standard for covering large skin defects. However, STSGs usually bring complications to the donor sites.
- Trial name
- NCT05571904
- Testing
- thick STSG; thin STSG
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Partial-thickness Burn Wounds
Evaluating Whether Intact Fish Skin Graft Can Decrease the Need for Autograft in the Treatment of Deep Partial-Thickness Burns
The goal of this randomized controlled clinical trial is to determine whether use of Kericis Intact Fish Skin Graft (IFSG) can decrease the amount of autograft tissue needed for treatment of deep partial-thickness burns in…
- Trial name
- LOGI (NCT07326657)
- Testing
- Intact fish skin graft, autograft
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Kerecis Ltd.
Split Thickness Skin Graft, Skin Cancer Excision Site
SNaP Wound Care System Over Skin Cancer Excision Sites and Split Thickness Skin Grafts (STSGs)
The purpose of this study is to evaluate the efficacy of the Spiracur SNaP® Wound Care System for the treatment of skin cancer excision sites and split thickness skin grafts (STSG).
- Conditions
- Split Thickness Skin Graft, Skin Cancer Excision Site, Skin Graft
- Trial name
- NCT01349894
- Testing
- SNaP® Wound Care System
- Where
- United States
- Sponsor
- Solventum US LLC
Split-thickness Skin Graft Donor Sites, Wound Healing
Effectiveness of Negative Pressure Wound Therapy Dressing on Split-Thickness Skin Graft Donor Site Wound Healing
Split-thickness skin grafting (STSG) is a cornerstone of reconstructive surgery, but donor sites often experience significant morbidity due to partial-thickness wounds created.
- Trial name
- NCT07629076
- Testing
- Negative Pressure Wound therapy, conventional dressing
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Mahmoud Abdalla Hifny Taha
Chronic Venous Hypertension With Ulcer and Inflammation, Chronic Ulcer of Leg or Foot
Role of Platelet Rich Plasma in Enhancing Graft Take in Chronic Venous Ulcers
Chronic venous ulcers are considered a problem with a big morbidity impact on both the health facilities and patients, skin-grafting have shown not so perfect outcomes with such ulcers.
- Trial name
- NCT03526913
- Testing
- PRP, STSG
- Volunteers
- 20 people
- Sponsor
- Noha Mohsen Omar
Wound Heal
Utility of Restrata With Split Thickness Skin Graft to Reconstruct the Forearm Donor Site
Understand association between use of Restrata (Acera Surgical Inc., St. Louis, MO) in forearm flap reconstruction with donor site healing and function
- Trial name
- NCT04829331
- Testing
- Restrata
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Acera Surgical, Inc.
Wound Closure, Wound Care
Safety Study of Microlyte DualGuard
The primary purpose of this research is to evaluate the safety and effectiveness of Microlyte® DualGuard wound dressing in the healing of partial thickness donor site wounds, also known as skin graft donor sites.
- Trial name
- SAGGA (NCT07695688)
- Testing
- Microlyte DualGuard, Allevyn Foam (Standard of Care Control)
- Where
- 3 sites in United States
- Volunteers
- 53 people
- Sponsor
- Imbed Biosciences
Skin Graft Disorder, Disorder of Skin Donor Site
Wound-healing Improvement by Resurfacing Split-Thickness Skin Donor Sites With Thin Split-thickness Grafting
Split-thickness skin grafting remains fundamental treatment of patients with deep burns and other traumatic injuries. However, the split-thickness skin graft (STSG) donor site dressing has been controversial until now.
- Conditions
- Skin Graft Disorder, Disorder of Skin Donor Site, Wound Healing Disturbance of
- Trial name
- NCT01974583
- Testing
- regrafted with thin split-thickness skin graft, covered with the occlusive hydrocellular dressing, covered with paraffin gauze
- Volunteers
- 192 people
- Sponsor
- Tang-Du Hospital
Skin Graft Disorder, Donor Site Complication
Impact of Prisma on Donor Site Pain
The purpose of this study is to assess the feasibility of evaluating the use of a composite collagen, silver-oxidized regenerated cellulose matrix compared to the standard of care dressing on donor site pain for patients…
- Trial name
- NCT04050124
- Testing
- Promogran Prisma, Standard of care (SOC) dressings
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- NYU Langone Health
Burns
Study With an Autologous Dermo-epidermal Skin Substitute for the Treatment of Burns in Children
This phase IIb trial aims to evaluate the efficacy and safety of EHSG-KF (synonym denovoSkin) in comparison to meshed STSG in children with partial deep dermal and full thickness burns.
- Trial name
- NCT03229564
- Testing
- EHSG-KF, STSG
- Where
- 4 sites in Italy, Netherlands and 1 more
- Volunteers
- 12 people
- Sponsor
- CUTISS AG
Skin Graft
Compare of Petrolatum Gauze, Allevyn, and New Dressing, Betafoam® in the Management of Split-Thickness Skin Graft Donor Site
This study is a randomized, controlled, multi-centre, open-label, phase IV study. Total 81 patients will be enrolled in this study.
- Trial name
- NCT02543034
- Testing
- Betafoam Wound Dressing, Petrolatum Gauze, Allevyn Wound Dressing
- Where
- South Korea
- Volunteers
- 105 people
- Sponsor
- Mundipharma Korea Ltd
Head and Neck Cancer
Utility of Restrata With Split-thickness Skin Graft to Reconstruct the Forearm Donor Site
Adult patients undergoing a radial forearm free flap or ulnar forearm free flap will be randomized to the use of the Restrata graft in combination with split-thickness skin graft for reconstruction.
- Trial name
- NCT04880603
- Testing
- Restrata Graft, Standard of Care Skin Graft
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Nebraska Methodist Health System
Partial-thickness Skin Donor Sites
Altrazeal™ Versus Aquacel® Ag for Partial Thickness Skin Donor Sites
The primary objective of the study is to evaluate the time to wound healing in skin graft donor sites with a new treatment (Altrazeal dressing) compared to standard of care treatment (Aquacel Ag- Carboxymethylcellulose dressing)…
- Trial name
- NCT01062204
- Testing
- Altrazeal, Aquacel Ag
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- ULURU Inc.
Diabetic Foot, Ulcer Foot
Bioactive Split Thickness Skin Allograft Versus Standard of Care in the Treatment of Diabetic Foot Ulcers
This study is a prospective, multi-center, randomized controlled trial designed to collect patient outcome data as well as assess performance and safety of a commercially available human split thickness skin allograft with SOC…
- Trial name
- NCT04040426
- Testing
- Human split thickness skin allograft, Additional Outer Dressing Applicaiton, Offloading
- Where
- 5 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Professional Education and Research Institute
Burns
A Prospective, Descriptive Cohort Study With Prontosan® Wound Gel X in Partial and Full Thickness Burns Requiring Split Thickness Skin Grafts
The purpose of this study is to evaluate the healing of split thickness skin grafts when treated with Prontosan® Wound Gel X in patients with partial and full thickness skin burns.
- Trial name
- NCT01534858
- Testing
- Prontosan Wound Gel X
- Where
- 3 sites in Germany
- Volunteers
- 51 people
- Sponsor
- B. Braun Ltd. Centre of Excellence Infection Control
Wound, Donor Site Complication
Clinical Efficacy and Safety of Sericin Hydrogel Sheet Impregnated With Bird's Nest Extract
Split-thickness skin graft (STSG) is one of the most common procedures performed in plastic surgery and dermatology. The donor site of skin grafting is expected to heal without scarring.
- Conditions
- Wound, Donor Site Complication, Skin Graft Scar, Scar Conditions and Fibrosis of Skin
- Trial name
- NCT04997863
- Testing
- Sericin hydrogel sheet impregnated with EBN extract
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Chulalongkorn University
Wounds
Oleogel-S10 in Wound Healing of Split-Thickness Skin Graft Donor Sites (BSG-12)
The main purpose of this phase III clinical trial was to show safety and efficacy of Oleogel-S10 in accelerating the wound healing of Split-Thickness Skin Graft (STSG) donor sites.
- Trial name
- BSG-12 (NCT01807650)
- Testing
- Oleogel-S10, non-adhesive wound dressing, Non-adhesive wound dressing only
- Where
- 14 sites in France, Greece and 2 more
- Volunteers
- 112 people
- Sponsor
- Birken AG
Skin Graft Complications
Factors Affecting Split Thickness Skin Graft Success Rates in Patients Who Underwent a Radial Forearm or Fibula Free Flap
Fibula free flaps (FFF) and radial forearm free flaps (RFFF) are necessary to reconstruct parts of the face after cancer surgery, traumas, or debilitating infections.
- Trial name
- NCT04648267
- Testing
- Cast and bolster placement duration, Standard of care
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of Southern California