Clinical trials: Spondyloarthritis, Axial
Anti - TNF Therapy, Ankylosing Spondylitis
Anti-TNF Therapy and Nerve Conduction Studies in Ankylosing Spondylitis
Patients with ankylosing spondylitis were divided into 2 groups as anti-TNF and conventional therapy according to the treatments they were using for the last 5 years.
- Conditions
- Anti - TNF Therapy, Ankylosing Spondylitis, Neuropathy
- Trial name
- NCT04943237
- Testing
- Anti-TNF agents, Conventional therapy users for the last 5 years
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Ankylosing Spondylitis, Sexual Dysfunction
Association of Erectile Dysfunction With Neuropathic Pain, Disease Activity, and Functional Status in Male Patients With Axial Spondyloarthritis: A Cross-Sectional Observational Study
tudy Description Definitions Use this module to describe the study protocol. Required § Required if Study Start Date is on or after January 18, 2017 [*] Conditionally required Brief Summary Use these resources to provide…
- Trial name
- NCT07453628
- Testing
- Anti-TNF agents, NSAIDs, No Treatment (Healthy Controls)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Altuğ Güner
Spondylitis, Spondylitis, Ankylosing
A Pilot Study of MSCs Iufusion and Etanercept to Treat Ankylosing Spondylitis
The purpose of this study is to evaluate the safety and clinical effect of mesenchymal stem cells (MSCs) derived from human bone marrow at a dose of 1.0E+6 MSC/kg in subject for the therapy of Ankylosing spondylitis (AS) and to…
- Conditions
- Spondylitis, Spondylitis, Ankylosing, Ankylosis, Arthritis
- Trial name
- NCT02809781
- Testing
- Intravenous infusion of MSCs, Etanercept
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Axial Spondyloarthritis, Ankylosing Spondylitis
A Study to Assess the Safety of Subcutaneous Secukinumab for Treatment in Adult Indian Participants With Axial Spondyloarthritis (axSpA), Ankylosing Spondylitis (AS), and Non-Radiographic Axial Spondyloarthritis (nr-axSpA)
The aim of this study is to assess the safety of secukinumab in Indian adult participants with axSpA, AS, and nr-axSpA over a 16-week treatment period.
- Conditions
- Axial Spondyloarthritis, Ankylosing Spondylitis, Non-Radiographic Axial Spondyloarthritis
- Trial name
- NCT07737730
- Volunteers
- 60 people
- Sponsor
- Novartis Pharmaceuticals
Ankylosing Spondylitis, Swallowing Disorder.Other Specified
Evaluation of Functions of Swallowing and Voice in Ankylosing Spondylitis Patients
In this study was to determine whether changes that occurred over time had an impact on the swallowing and voice functions depend of Ankylosing spondylitis patients.
- Conditions
- Ankylosing Spondylitis, Swallowing Disorder.Other Specified, Voice Alteration
- Trial name
- NCT04437394
- Testing
- flexible endoscopic evaluation of swallowing, The analysis of voice
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yavuz Atar
Rheumatoid Arthritis (RA, Ankylosing Spondylitis
Skin Autofluorescence Assessment of Advanced Glycation End Products in Rheumatic Diseases
Rheumatic diseases are chronic inflammatory conditions that can lead to long-term tissue damage and increased cardiovascular and metabolic risk.
- Conditions
- Rheumatoid Arthritis (RA, Ankylosing Spondylitis, Psoriatic Arthritis, Reactive Arthritis (ReA)
- Trial name
- NCT07329556
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Bursa City Hospital
Moderate to Severe Active Axial Spondyloarthritis
Enbrel-Sulfasalazin-Early-Axial Spondyloarthritis (AS)
Efficacy - To assess efficacy of etanercept versus sulfasalazine when added to NSAIDs in patients with moderate to severe active early axial spondyloarthritis duration of ongoing axial symptoms of less than 5 years.
- Trial name
- NCT00844142
- Testing
- Etanercept 25mg, Sulfasalazine
- Where
- 9 sites in Germany
- Volunteers
- 80 people
- Sponsor
- Charite University, Berlin, Germany
Ankylosing Spondylitis
The Effect of Fecal Microbiota Transplantation in Ankylosing Spondylitis (AS) Patients.
Ankylosing spondylitis (AS) patients often have subclinical gut wall inflammation. Gut dysbiosis has been associated with both AS and Crohn disease, both of which have several features in common.
- Trial name
- ASGUT (NCT03726645)
- Testing
- Fecal microbiota transplantation
- Where
- Finland
- Volunteers
- 20 people
- Sponsor
- Hospital District of Helsinki and Uusimaa
Axial Spondyloarthritis
Unmet Needs of Axial Spondyloarthrits in Egyptian Patients
During the past decade, the well-known disease called Ankylosing Spondylitis has come to be considered as a subset of the broader entity referred as axial spondyloarthritis (axSpA), which also includes non-radiographic axSpA.
- Trial name
- NCT05517031
- Testing
- ASDAS score , VAS score, BASFI score , Katz ADL index
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Ankylosing Spondylitis, AS
Expression of Tim-3 on Neutrophils in Ankylosing Spondylitis
1. To investigate the expression of Tim-3 on neutrophils in ankylosing spondylitis patients and its correlation with disease activity and inflammatory markers. 2.
- Conditions
- Ankylosing Spondylitis, AS, Tim3
- Trial name
- NCT07383805
- Where
- Egypt
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Assiut University
Ankylosing Spondylitis
Prednisolone in Active Ankylosing Spondylitis (AS)
1. to investigate whether steroids are effective in ankylosing spondylitis 2. if steroids are effective to describe how quick they work
- Trial name
- NCT00244166
- Testing
- prednisolone
- Where
- 3 sites in Germany
- Volunteers
- 75 people
- Sponsor
- Charite University, Berlin, Germany
Ankylosing Spondylitis
A Study to Evaluate the Long Term Safety and Efficacy of Bimekizumab in Subjects With Ankylosing Spondylitis
This is a study to assess the long term safety and tolerability of bimekizumab in subjects with ankylosing spondylitis
- Trial name
- BE AGILE 2 (NCT03355573)
- Testing
- Bimekizumab
- Where
- 50 sites in United States, Bulgaria and 8 more
- Volunteers
- 255 people
- Sponsor
- UCB Biopharma SRL
Ankylosing Spondylitis
Effect of Inspiratory Muscle Training on Respiratory Functions and Exercise Capacity
In this study, we aimed to evaluate the effect of Anti- tumor necrosis factor (TNF) treatment on pulmonary functions in patients with AS and to evaluate the pulmonary functions and exercise performance of patients by adding…
- Trial name
- NCT06287983
- Testing
- Inspiratory Muscle Trainer (IMT) (POWERbreathe Medic Classic), The Sample Spondylitis Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Kayseri City Hospital
Ankylosing Spondylitis, Balance Assessment
Ultrasound Assessment of Neck Muscles and Balance in Male Patients With Ankylosing Spondylitis
The aim of this study is to evaluate the relationship between ultrasonographic measurements of the cervical muscles and balance parameters in patients diagnosed with ankylosing spondylitis (AS)
- Conditions
- Ankylosing Spondylitis, Balance Assessment, Balance, Spondylarthropathies; Spondylitis, Ankylosing
- Trial name
- NCT06967883
- Testing
- Ultrasonographic assessment of Cervical Multifidus and Longus Colli Muscle Thickness, Postural Balance and Limit of Stability using the balance platform,Cervical Flexion and Extension Strength
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Ankylosing Spondylitis
Special Investigation in Patients With Ankylosing Spondylitis (All Patients Investigation)
This study of adalimumab (Humira) will be conducted to clarify the following with regard to the treatment of ankylosing spondylitis with this drug: Unknown adverse drug reactions (especially important adverse drug reactions)…
- Trial name
- NCT01329380
- Where
- 194 sites in Japan
- Volunteers
- 403 people
- Sponsor
- AbbVie
Ankylosing Spondylitis, Psoriatic Arthritis
Functional Limitations Due To The Foot Involvement In Spondyloarthritis
Seronegative spondyloarthritis (SpA) is a group of rheumatic diseases Foot involvement of the SpA is common and enthesitis, erosive changes or ankylosis are the frequent lesions.
- Trial name
- NCT01833468
- Volunteers
- 30 people
- Sponsor
- Vakif Gureba Training and Research Hospital
Ankylosing Spondylitis
Methotrexate in Ankylosing Spondylitis (MTX in AS)
Assessing the efficacy and tolerability of methotrexate 15mg sc in the first month of treatment- if well tolerated methotrexate 20mg sc in the following 3 months in patients with active anklyosing spondylitis
- Trial name
- NCT00243750
- Testing
- Methotrexate
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Charite University, Berlin, Germany
Spondylitis, Ankylosing
Blocking Tumor Necrosis Factor in Ankylosing Spondylitis
The Division of Rheumatology at University of California San Francisco is conducting a research study on the treatment of ankylosing spondylitis (AS) with a new therapy currently used for people with other forms of arthritis.
- Trial name
- NCT00000433
- Testing
- Anti-Tumor Necrosis Factor
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Ankylosing Spondylitis
A Randomized Trial of Ultrasound-Guided Acupotomy for Ankylosing Spondylitis
This study employs a randomized controlled trial methodology to systematically evaluate the efficacy and safety of a modified acupotomy technique in the treatment of ankylosing spondylitis.
- Trial name
- UGA-AS RCT (NCT07578220)
- Testing
- Ultrasound-guided acupotomy
- Where
- China
- Volunteers
- 60 people
- Sponsor
- China-Japan Friendship Hospital
Axial Spondyloarthritis
Study of the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of BCD-180 in Patients With Axial Spondyloarthritis (LEVENTA)
The aim of the study is to evaluate the efficacy, safety, immunogenicity, pharmacokinetics and pharmacodynamics of a fixed dose of study drug (BCD-180) in comparison with placebo in patients with active axial spondyloarthritis…
- Trial name
- NCT06333210
- Testing
- anti-TRBV9 monoclonal antibody infusions, Adalimumab subcutaneous injection
- Where
- 32 sites in Belarus, Russia
- Volunteers
- 421 people
- Sponsor
- Biocad