Clinical trials: Sprains
Carpal Tunnel Syndrome
Safety and Efficacy of a Novel Carpal Tunnel Tissue Manipulation Device in Treating Carpal Tunnel Syndrome
A single-center, prospective, non-randomized study to evaluate the safety and efficacy of a novel carpal tunnel tissue manipulation device in treating symptoms and decreased physical function in subjects previously diagnosed with…
- Trial name
- NCT02534493
- Testing
- Carpal Tunnel Tissue Manipulation Device (CTMD)
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Pressure Profile Systems, Inc.
Acute Pain
A Double-blind, Double-dummy, Multicenter, Randomized Study of the Efficacy and Tolerability of Valdecoxib 40 mg Versus Rofecoxib 50 mg in Treating the Symptoms of Ankle Sprain
The study compares valdecoxib 40 mg once daily vs. rofecoxib 50 mg one daily in treating the signs and symptoms of acute first- or second-degree ankle sprain.
- Trial name
- NCT00657449
- Testing
- valdecoxib, rofecoxib
- Where
- 8 sites in Brazil
- Volunteers
- 45 people
- Sponsor
- Pfizer
Ankle Sprain
HKT-500 in the Treatment of Adult Patients With Ankle Sprain
The objective of this study is to demonstrate the multiple-dose efficacy and safety of HKT-500 for the treatment of ankle sprain.
- Trial name
- NCT00927641
- Testing
- Ketoprofen Patch
- Where
- 25 sites in United States
- Volunteers
- 240 people
- Sponsor
- Hisamitsu Pharmaceutical Co., Inc.
Ankle Sprain
FS-67 in the Treatment of Pediatric Patients With Ankle Sprain
The objective of this study is assess the efficacy and safety of single and multiple applications of the FS-67 patch in the treatment of ankle sprain in pediatric population (ages 13-17).
- Trial name
- NCT01037816
- Testing
- FS-67 Patch
- Where
- 23 sites in United States
- Volunteers
- 252 people
- Sponsor
- Hisamitsu Pharmaceutical Co., Inc.
Acute Low Back Pain
Efficacy and Safety of Dexketoprofen/Vitamin B Vs Dexketoprofen for Post-traumatic Cervical Sprain Grade I-II
Phase IIIb, multicenter, prospective, randomized, double-blind study to evaluate the fixed combination of Desketoprofen / Vitamin B in the management of acute pain in patients with cervical sprain grade I-II of the Quebec scale.
- Trial name
- WHIPLASH (NCT05001555)
- Testing
- Dexketoprofen/Vitamin B, Dexketoprofen
- Where
- Mexico
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Laboratorios Silanes S.A. de C.V.
Ankle Sprains
Phase III Trial to Evaluate the Efficacy and Safety in Patients With Ankle Sprains.
This study is a multi-center, double-blind, randomized controlled trial to evaluate the efficacy and safety of EFTS vs. placebo in patients with ankle sprains.
- Trial name
- NCT06866613
- Testing
- Esflurbiprofen Topical System (EFTS)
- Where
- 5 sites in Germany
- Volunteers
- 69 people
- Sponsor
- Teikoku Seiyaku Co., Ltd.
Ankle Injuries, Syndesmotic Injuries
Grappler® Interference Screw Post-Market Clinical Follow-Up Study
Ambispective, multi-surgeon, single site, consecutive case series to determine the safety, performance, and benefits of the Grappler(R) Interference Screw.
- Conditions
- Ankle Injuries, Syndesmotic Injuries, Ankle Inversion Sprain, Deltoid Ankle Sprain
- Trial name
- NCT04893824
- Testing
- Grappler® Interference Screw System
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Paragon 28
Ankle Sprain
TRAUMED - a Clinical Trial in Acute Ankle Sprain
TRAUMED - a randomized clinical trial evaluating the efficacy and safety of Traumed® gel in patients with acute ankle sprain.
- Trial name
- TRAUMED (NCT06192420)
- Testing
- Traumeel®, Diclofenac sodium gel 1%
- Where
- Germany
- Volunteers
- 809 people
- Sponsor
- Biologische Heilmittel Heel GmbH
Sprain of Ankle
TAASS-Traumeel Ointment and Gel Compared With a Topical NSAID in Athletes With Acute Ankle Sprain
The objective of this study is to determine the efficacy of Traumeel S (both ointment and gel) compared to another antiinflammatory drug called Diclofenac in patients with a sprained ankle.
- Trial name
- TAASS (NCT01066520)
- Testing
- Traumeel S ointment, Traumeel S gel, Diclofenac gel
- Where
- Spain
- Volunteers
- 449 people
- Sponsor
- Biologische Heilmittel Heel GmbH
Ankle Sprain, Back Pain
Counterpain PXM Versus Diclofenac Versus Piroxicam
The goal of this clinical trial is to learn if a gel containing Piroxicam plus Counterirritant (warming/cooling ingredients) is as effective and safe as two other common anti-inflammatory gels for treating acute muscle, bone, and…
- Conditions
- Ankle Sprain, Back Pain, Osteoarthritis (OA) of the Knee, Tennis Elbow
- Trial name
- NCT07475663
- Testing
- Piroxicam plus Counterirritant (brand name Counterpain® PXM)., Diclofenac Sodium 10 mg (Brand Name Hotin® DCL), Piroxicam 0.5% (Brand name Pirofel® gel)
- Where
- Indonesia
- Volunteers
- 180 people
- Sponsor
- Taisho Pharmaceutical Indonesia
Ankle Sprain
Diclofenac Patch for Treatment of Mild to Moderate Ankle Sprain
The primary purpose of this study is to assess the effectiveness of once daily application of a diclofenac sodium patch to the skin near or over the painful area.
- Trial name
- NCT00640705
- Testing
- diclofenac sodium
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- Cerimon Pharmaceuticals
Trigger Finger, Trigger Thumb
Clinical Investigation on Safety, Performance and Effectiveness of Sono-instruments
Carpal Tunnel (CT) syndrome is a collection of characteristic symptoms and signs that occurs following compression of the median nerve within the CT.
- Conditions
- Trigger Finger, Trigger Thumb, Carpal Tunnel Syndrome
- Trial name
- SONO-01 (NCT05435950)
- Testing
- Sono-Intruments
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Spirecut
Arthrogenic Muscle Inhibition, Arthrogenic Muscle Inhibitions
Evaluation of the Efficacy of the ALLYANE Procedure in the Treatment of Central Motor Inhibition
The goal of this clinical study is to determine the effectiveness of restoring muscle strength in the management of motor inhibition when complemented by the ALLYANE process (neuro-motor reprogramming) compared to a standard…
- Trial name
- NCT06774157
- Testing
- A session combining motor imagery and listening to low frequency sounds, Standard management - Control group
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Allyane
Sport Medicine
ATI Evidence-based Guide Investigating Medical and Preventative Services
To use existing standard-of-care documentation in a sports medicine electronic medical record (EMR) to evaluate patient characteristics, interventions delivered, utilization management, and clinical outcomes in routine sports…
- Trial name
- NCT04050319
- Testing
- Screening and diagnosis if injured
- Where
- United States
- Volunteers
- 550,000 people, healthy volunteers welcome
- Sponsor
- ATI Holdings, LLC
Ankle Injuries, Syndesmotic Injuries
Grappler Interference Screw Post-Market Collection of Patient Reported Outcome Measures
Ambispective, multi-surgeon, single site, consecutive case series to determine the safety, performance, and benefits of the Grappler(R) Interference Screw.
- Conditions
- Ankle Injuries, Syndesmotic Injuries, Ankle Inversion Sprain, Deltoid Ankle Sprain
- Trial name
- NCT05190874
- Testing
- Grappler Interference Screw System
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Paragon 28
Sprains and Strains, Pain
A Safety and Effectiveness Study of Acetaminophen Extended Release (3900 mg/Day) and Ibuprofen (1200 mg/Day) in the Treatment of Pain Associated With Ankle Sprains.
The purpose of this study is to compare the safety and effectiveness of 1300 mg acetaminophen extended release given three times daily for nine days to that of 400 mg ibuprofen given three times daily for nine days for the signs…
- Trial name
- NCT00261560
- Testing
- acetaminophen
- Volunteers
- 260 people
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Grade I/II Ankle Sprain
Firefly ANKLE Sprain Study
The device to be tested (fireflyTM) stimulates the common peroneal nerve and causes the foot to twitch, and has been shown to increase blood flow. The device is also indicated for the treatment of oedema.
- Trial name
- NCT02307955
- Testing
- firefly, Standard of care
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- Firstkind Ltd
Pain
A Multicenter Efficacy Study of a Diclofenac+Menthol Gel in Subjects With Ankle Sprain
This Phase III pivotal efficacy study will assess efficacy and onset of pain relief of MFC51123 gel vs. placebo and MFC51123 gel vs.
- Trial name
- NCT02100670
- Testing
- 1% diclofenac sodium plus 3% menthol, 1% diclofenac sodium plus 0.09% menthol, 3% menthol
- Where
- 3 sites in Germany
- Volunteers
- 385 people
- Sponsor
- GlaxoSmithKline
Sprain of Ankle
Evaluation of the Effect of the Association of Proton Pump Inhibitor (PPIs) With Non-Steriodal Anti-Inflamatories (NSAIDs) in Work Leave Time.
Retrospective cohort study to evaluate the effect of the association of PPIs with NSAIDs in work leave time.
- Trial name
- NCT00717119
- Where
- Spain
- Volunteers
- 6,356 people
- Sponsor
- AstraZeneca
Postherpetic Neuralgia, Diabetic Neuropathy
A Study Of Lidocaine Patch 5% Alone, Gabapentin Alone, And Lidocaine Patch 5% And Gabapentin In Combination For The Relief Of Pain In Patients With Diverse Peripheral Neuropathic Pain Conditions
Patients with postherpetic neuralgia (PHN), diabetic neuropathy (DN), complex regional pain syndrome (CRPS), carpal tunnel syndrome, HIV neuropathy, idiopathic sensory neuropathy, or other peripheral neuropathy participated in a…
- Conditions
- Postherpetic Neuralgia, Diabetic Neuropathy, Complex Regional Pain Syndrome, Carpal Tunnel Syndrome
- Trial name
- NCT00904202
- Testing
- Gabapentin + Lidoderm®
- Where
- 7 sites in United States
- Volunteers
- 62 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company