Clinical trials: Stage 5 Chronic Kidney Diseases
End-Stage Renal Disease (ESRD) Chronic Kidney Disease, Stage 5 Renal Regeneration Anuria Diabetic Nephropathy, Anuria
Clinical Observation of Renal Function Reactivation Following a GRAS-Based Protocol in Patients With Chronic Kidney Disease and Long-Term Renal Arrest.
This observational study documents the impact of a specific oral protocol (based on FDA-GRAS ingredients) on patients with Stage 5 Chronic Kidney Disease (CKD).
- Conditions
- End-Stage Renal Disease (ESRD) Chronic Kidney Disease, Stage 5 Renal Regeneration Anuria Diabetic Nephropathy, Anuria, End-Stage Renal Disease (ESRD), Chronic Kidney Disease, Stage 5
- Trial name
- NCT07555327
- Testing
- CSR-CKD Oral Protocol
- Where
- Algeria
- Volunteers
- 8 people
- Sponsor
- Amar h Zireg
Chronic Kidney Disease
Oral Paricalcitol in Stage 3 - 5 Chronic Kidney Disease
The purpose of this study is to test the hypothesis that selective vitamin D receptor activation reduces left ventricular hypertrophy and ameliorates inflammation and atherosclerosis in stage 3 -5 chronic kidney disease.
- Trial name
- NCT00796679
- Testing
- paricalcitol
- Where
- 2 sites in Hong Kong
- Volunteers
- 60 people
- Sponsor
- The University of Hong Kong
Chronic Kidney Disease Stage 3, Chronic Kidney Disease Stage 4
Assessing Perceived Versus Actual Knowledge and Quality of Life in Pre-Dialysis Chronic Kidney Disease (CKD) Patients
Aims: The investigators' primary objective is to assess both perceived and actual disease knowledge in local pre-dialysis Chronic Kidney Disease (CKD) patients.
- Conditions
- Chronic Kidney Disease Stage 3, Chronic Kidney Disease Stage 4, Chronic Kidney Disease Stage 5
- Trial name
- NCT01509716
- Where
- Singapore
- Volunteers
- 400 people
- Sponsor
- National University of Singapore
Chronic Kidney Disease (CKD) Stage 5
Effect of Pre-emptive Assessment of Self-care Peritoneal Dialysis (PD) Ability on PD Choice in Patients With Stage 5 Chronic Kidney Disease
Peritoneal dialysis is an effective renal replacement therapy with higher quality of life and lower treatment cost than hemodialysis.However, the application rate of peritoneal dialysis is much lower than that of hemodialysis.
- Trial name
- NCT04967547
- Testing
- Self-care PD ability assessment form, Education
- Where
- China
- Volunteers
- 232 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Chronic Kidney Disease Stage 5 on Dialysis, Chronic Kidney Disease Stage 5 With Transplant
Vaccination Against COVID-19 in Chronic Kidney Disease
This is a prospective, multi-center, observational study that will enroll patients receiving dialysis (hemodialysis or peritoneal dialysis) or patients with kidney transplantation who will be vaccinated against COVID-19.
- Conditions
- Chronic Kidney Disease Stage 5 on Dialysis, Chronic Kidney Disease Stage 5 With Transplant, Vaccine Response Impaired
- Trial name
- NCT04743947
- Testing
- No intervention; observational study
- Where
- 5 sites in Germany
- Volunteers
- 400 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Chronic Kidney Disease (Stages 4 and 5), Health Related Quality of Life
Symptom Monitoring With Supported Feedback in Advanced Chronic Kidney Disease
Patient-reported outcome measures (PROMs) are validated tools to reliably measure outcomes highly prioritized by patients, such as health-related quality of life (HRQOL) and symptoms, but the current clinical impact of PROMs is…
- Trial name
- NCT07186218
- Testing
- Electronic patient-reported outcome measure (ePROM) for symptom monitoring
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Massachusetts General Hospital
Chronic Kidney Disease Stage 5 (Dialysis Dependent)
A Randomized, Comparative, Open-label Study of IV Monofer® Administered as Maintenance Therapy by Single or Repeated Bolus Injections in Comparison With IV Iron Sucrose in Subjects With CKD-5D
The purpose of this study is to compare the efficacy and safety of intravenous iron isomaltoside 1000 with intravenous iron sucrose in patients suffering from Stage 5 Chronic Kidney Disease on Dialysis Therapy (CKD-5D).
- Trial name
- NCT01222884
- Testing
- Monofer, Iron sucrose
- Where
- India
- Volunteers
- 351 people
- Sponsor
- Pharmacosmos A/S
Chronic Kidney Diseases
Competing Risk of Death and ESRD in Incident CKD Patients
Although chronic kidney disease (CKD) affects a growing number of people, epidemiologic data on incident CKD in the general population are scarce. Screening strategies to increase early CKD detection have been developed.
- Trial name
- EPIRAN (NCT03379571)
- Volunteers
- 631 people
- Sponsor
- Central Hospital, Nancy, France
Chronic Kidney Disease (Stages 4 and 5)
Kidney RISE: Randomized Integrated Supportive CarE Trial
The purpose of study is to investigate whether adding palliative care to usual chronic kidney disease (CKD) care improves symptoms and quality of life for people with CKD.
- Trial name
- NCT07741357
- Testing
- Kidney RISE
- Where
- 2 sites in United States
- Volunteers
- 280 people
- Sponsor
- NYU Langone Health
Chronic Kidney Disease Stage 5
Shared Decision Making for Choosing renAl Replacement Therapy in Chronic Kidney Disease Patients
Shared decision making (SDM) is an approach where clinicians and patients make decisions together using the best available evidence.
- Trial name
- SDM-ART (NCT04976166)
- Testing
- Education
- Where
- 19 sites in South Korea
- Volunteers
- 1,194 people
- Sponsor
- Seoul National University Hospital
Secondary Hyperparathyroidism Due to Renal Causes, Chronic Kidney Diseases
Safety, Efficacy, PK and PD of CTAP101 (Calcifediol) ER Capsules for SHPT in HD Patients VDI
Safety, Efficacy, PK and PD of CTAP101 (calcifediol) ER Capsules for SHPT in HD Patients VDI
- Conditions
- Secondary Hyperparathyroidism Due to Renal Causes, Chronic Kidney Diseases, Vitamin D Deficiency, Stage 5 Chronic Kidney Disease
- Trial name
- NCT03602261
- Testing
- Calcifediol Oral Capsule
- Where
- 18 sites in United States
- Volunteers
- 44 people
- Sponsor
- OPKO Health, Inc.
Chronic Kidney Disease (CKD), End-Stage Renal Disease (ESRD)
Malnutrition, Diet and Racial Disparities in Chronic Kidney Disease (CKD)
In the United States, African Americans are 3.6 time and Hispanics 1.5 times more likely to suffer from chronic kidney disease and need dialysis treatment for life, when compared to the non-Hispanic Whites.
- Trial name
- MADRAD (NCT01415570)
- Where
- United States
- Volunteers
- 1,050 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Chronic Kidney Disease (Stages 4 and 5), Peritoneal Dialysis (PD)
Probiotic and Prebiotic Supplementation in Peritoneal Dialysis Patients
The goal of this clinical trial is to learn if synbiotics work to lower inflammation in adults with chronic kidney disease who are on peritoneal dialysis.
- Trial name
- NCT07694791
- Testing
- Synbiotic
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Hospital Universitario Dr. Jose E. Gonzalez
Secondary Hyperparathyroidism, End-Stage Renal Disease
Study to Evaluate Safety of Vitamin D Receptor Activators in Patients Ages 0 to 16 With Chronic Kidney Disease Stage 5 Receiving Peritoneal Dialysis Within Current Clinical Practice
The objective of this study was to observe the safety of paricalcitol utilization in pediatric participants (ages 0 to 16 years old) being treated for secondary hyperparathyroidism (SHPT).
- Trial name
- NCT01134315
- Testing
- Paricalcitol, Calcitriol
- Where
- 18 sites in United States
- Volunteers
- 61 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Chronic Kidney Diseases, Atrial Fibrillation
Stroke Prophylaxis With Apixaban in Chronic Kidney Disease Stage 5 Patients With Atrial Fibrillation
Objective: To study the efficacy and safety of apixaban as stroke prophylaxis in patients with chronic kidney disease (CKD) stage 5 and atrial fibrillation (AF) with or without dialysis treatment.
- Conditions
- Chronic Kidney Diseases, Atrial Fibrillation, Stroke, Intracerebral Hemorrhage
- Trial name
- SACK (NCT05679024)
- Testing
- Apixaban 2.5 milligram Oral Tablet
- Where
- 34 sites in Finland, Iceland and 2 more
- Volunteers
- 1,400 people
- Sponsor
- Region Stockholm
Chronic Kidney Disease
Evaluate Safety and Efficacy of Paricalcitol in Reducing Serum Intact Parathyroid Hormone in Chronic Kidney Disease
Evaluate Safety and Efficacy of Paricalcitol in Reducing Serum Intact Parathyroid Hormone in Chronic Kidney Disease
- Trial name
- NCT01071070
- Testing
- paricalcitol
- Where
- 12 sites in China
- Volunteers
- 216 people
- Sponsor
- Abbott
Chronic Kidney Disease Stage V
A Comparative Analysis of Ray-Tech Sponge and Ice Bag Techniques in Kidney Transplantation
Warm ischemia during kidney transplantation is one of the important factors that negatively affect kidney function in the recipient.
- Trial name
- NCT06611189
- Testing
- surgery, Ray-Tech sponge technique
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 172 people
- Sponsor
- Okan University
Chronic Kidney Disease Stage 5 on Dialysis
Desidustat in the Treatment of Anemia in CKD on Dialysis Patients
A phase 3, multicenter, open-label, randomized, active-controlled study to evaluate the efficacy and safety of Desidustat Tablet versus Epoetin alfa Injection for the treatment of anemia in patients with CKD on dialysis. (DREAM-D)
- Trial name
- DREAM-D (NCT04215120)
- Testing
- Desidustat Oral Tablet, Epoetin Alfa
- Where
- 7 sites in India
- Volunteers
- 392 people
- Sponsor
- Zydus Lifesciences Limited
Chronic Kidney Disease Stage V
A Prospective, Open-label, Multi-center Pilot Study to Evaluate the Safety, Feasibility and Usability of the IDA
This is a multi-center, open label, cross-over clinical study. A total of 15 subjects will be enrolled to use the IDA for every peritoneal dialysis exchange for 14 days.
- Trial name
- CSP-027-21 (NCT05342935)
- Testing
- Inteligent Dialysis Assistant (IDA)
- Volunteers
- 15 people
- Sponsor
- liberDi Ltd.
Chronic Kidney Disease Stage 4, Chronic Kidney Disease Stage 5
A Communication-Priming Intervention to Improve Shared Decision-Making Between Older Adults With Advanced CKD and Clinicians
To achieve the goal of reaching consensus about the preferred treatment option that best aligns with the goals and values of patients, the investigators developed a 'CKD Jumpstart- Tips" priming tool tailored for older adults…
- Trial name
- NCT06799936
- Testing
- "CKD Jumpstart- Tips" priming intervention
- Where
- Hong Kong
- Volunteers
- 280 people
- Sponsor
- The University of Hong Kong