Clinical trials: Stage IV Esophageal Adenocarcinoma AJCC v7

Clinical Stage III Esophageal Adenocarcinoma AJCC v8, Clinical Stage III Esophageal Squamous Cell Carcinoma AJCC v8

Testing the Addition of an Anti-cancer Drug, Adavosertib, to Radiation Therapy for Patients With Incurable Esophageal and Gastroesophageal Junction Cancers

• Active, not recruiting
• Age: 18 years and older
• Phase 1
• Surgery or procedure
• Results posted

This phase I trial investigates the side effects and best dose of adavosertib and how well it works when given in combination with radiation therapy in treating patients with esophageal or gastroesophageal junction cancer for…

Conditions

Clinical Stage III Esophageal Adenocarcinoma AJCC v8, Clinical Stage III Esophageal Squamous Cell Carcinoma AJCC v8, Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8, Clinical Stage IV Esophageal Adenocarcinoma AJCC v8

Trial name

NCT04460937

Testing

Adavosertib, Radiation Therapy

Where

7 sites in United States

Volunteers

4 people

Sponsor

National Cancer Institute (NCI)