Clinical trials: Staining
Suspicious for Pulmonary Tuberculosis
Simple Verbal Intervention for Adequately Collecting Sputum
simple verbal intervention with figure of lung and upper respiratory tract will be helpful to adequately collecting sputum. and in the acceptable specimen based on Gram stain, positivity for AFB stain and culture rate will be…
- Trial name
- NCT01135043
- Testing
- education by brochure, control
- Where
- South Korea
- Volunteers
- 188 people
- Sponsor
- Seoul National University Hospital
Prostate Cancer
Infrared Fluorescence Staining Versus Frozen Section for Prostate Cancer Surgery
This study aims to validate the accuracy of the infrared fluorescence rapid detection technique for the diagnosis of prostate biopsy specimens, and to compare it with intraoperative frozen section and conventional paraffin…
- Trial name
- NCT07690462
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Xiangya Hospital of Central South University
Lupus Nephritis, IgA Nephropathy
The Correlation of Periostin and Renal Pathology in Chronic Kidney Disease Patients
The purpose of this study is to determine the location of periostin and urine periostin level in patients with lupus nephritis and IgA nephropathy.
- Trial name
- NCT02493101
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Oral Hygiene
A Study to Investigate the Stain and Plaque Removal Capability of Two Experimental Potassium Nitrate Dentifrices
The purpose of this study is to determine whether spherical silica can achieve similar or greater extrinsic dental stain and plaque removal, in comparison to dentifrices containing higher concentrations of standard abrasive…
- Trial name
- NCT03267511
- Testing
- 5% KNO3 / 0.2542% NaF dentifrice with 0.5% spherical silica, 5% KNO3 / 0.2542% NaF dentifrice with 1% spherical silica and 5% STP, 5% KNO3 / 0.2542% NaF dentifrice with 6% abrasive silica
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dental Pellicle
A Pilot Drug Trial That Evaluates the Whitening Potential of Nicotine Gum
The purpose of this research study is to evaluate the effects on existing tooth stain of nicotine gum. The study will enroll adults who have visible tooth staining.
- Trial name
- NCT00174499
- Testing
- 2 mg nicotine gum, 4 mg nicotine gum
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- McNeil AB
Eye Disease
Digital Photography to Evaluate Dry Eye
Surface eye problems (problems of the cornea and conjunctiva), such as dry eye, are often evaluated using ocular surface staining - the application of a colored dye to the surface of the eye.
- Trial name
- NCT00073099
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Eye Institute (NEI)
Stain Removal Efficacy
Extrinsic Tooth Whitening Evaluation of a Whitening Toothpaste
This randomized, examiner-blind, parallel-group clinical study evaluated the effectiveness of a whitening toothpaste compared with a control toothpaste in removing extrinsic tooth stain over six weeks of twice-daily unsupervised…
- Trial name
- NCT07428603
- Testing
- Whitening Test Dentifrice (Code 826), Control dentifrice (Code 378)
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- Church & Dwight Company, Inc.
Lipid Thickness
Investigating Abnormal Lipid Layer Thickness in Blepharoplasty Patients
Deficiency in tear film lipid layer thickness (LLT) has been implicated in the development of dry eye symptoms, and is influenced to a significant degree by the anatomy and function of the eyelids.
- Trial name
- NCT01787942
- Testing
- Tear Science LipiView
- Where
- Singapore
- Volunteers
- 60 people
- Sponsor
- Singapore National Eye Centre
Color Stability of Dental Ceramics, Zirconia Restorations
Impact of Khat Chewing on Color Stability and Patient Satisfaction of Multilayer Zirconia and Feldspathic Veneer Zirconia.
This study aims to evaluate and compare the impact of khat chewing on the color stability and patient satisfaction of multilayer zirconia and feldspathic veneered zirconia restorations.
- Conditions
- Color Stability of Dental Ceramics, Zirconia Restorations, Khat Chewing Effects, Dental Restoration Staining
- Trial name
- NCT07786272
- Testing
- Multilayer Zirconia Crowns, Feldspathic Veneered Zirconia Crowns
- Where
- Yemen
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Thamar University
Dental Plaque
Comparative Clinical Assessment of Charcoal and Conventional Toothbrushes
Oral hygiene practices are fundamental to maintaining oral health, preventing dental plaque accumulation, halitosis, stains, gingival and periodontal diseases, and improving overall quality of life.
- Trial name
- NCT07563413
- Testing
- charcoal toothbrush
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cairo University
Keratoconjunctivitis Sicca, Dry Eye
Safety and Efficacy Study of Rebamipide 2% Ophthalmic Suspension in Subjects With Dry Eye - Effects on Central Cornea
The purpose of this study is to evaluate the safety and efficacy of 2% rebamipide compared to placebo in clearing of fluorescein staining of the central cornea in subjects with dry eye disease.
- Trial name
- NCT01057147
- Testing
- rebamipide 2% ophthalmic suspension
- Where
- 19 sites in United States
- Volunteers
- 116 people
- Sponsor
- Kubota Vision Inc.
Lung Cancer, Intraoperative Pathology
The Application of Rapid Fresh Digital Pathology on the Diagnosis and Biomarker Testing of Lung Cancer
Through this project, the rapid staining process will be optimized for ex-vivo human lung specimens and integrate advanced ex-vivo mesoscale nonlinear optical gigascope.
- Conditions
- Lung Cancer, Intraoperative Pathology, 3D Pathology, Immunochemistry Staining
- Trial name
- NCT06497686
- Testing
- mesoscale nonlinear optical gigascope, Fluorescence microscope
- Volunteers
- 300 people
- Sponsor
- National Taiwan University Hospital
Bacterial Infections
Development and Accuracy Evaluation of Gram Staining Analysis AI
The investigators use Gram-stained specimens provided from clinical settings to develop and evaluate the accuracy of Gram staining analysis AI
- Trial name
- NCT06377592
- Testing
- Sample collection without intervention
- Where
- Japan
- Volunteers
- 18,000 people
- Sponsor
- GramEye
Port Wine Stains
Maximizing Laser Therapy Success for Port-Wine Birthmarks in Pediatric Patients
In this study the investigators aim to optimize Port-Wine-Birthmark (PBW) laser therapy in children in order to reduce the number of laser treatments required for clearance and improve outcomes for refractory cases.
- Trial name
- NCT07183644
- Testing
- Pulse Dye laser, Pulse Dye Laser (PDL) pulse width stacking, Pulse Dye Laser (PDL) followed by Nd:YAG (Neodymium-doped Yttrium Aluminum Garnet laser) laser.
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Texas Southwestern Medical Center
Colorectal Cancer, Monkey Pox
FOS Immunohistochemical Staining of Colorectal Cancer and Its Adjacent Tissues
Colorectal cancer tissue sections were obtained according to the inclusion criteria. The formalin was used to immersed all cancer specimens. And tissues were cut to 5 μm thickness and placed on glass slides before staining.
- Trial name
- NCT05698082
- Testing
- Immunohistochemical staining with anti-FOS
- Where
- China
- Volunteers
- 120 people
- Sponsor
- xiaoliang Huang
Atherosclerotic Cardiovascular Disease, Older Patients
LDL Cholesterol TARGETs in OLDer Patients (Age≥75 Years) With ASCVD (TARGET OLD)
To determine whether treating to an LDL-C target of 25 to <70 mg/dL is superior to an LDL-C target of 70 to <100 mg/dL with respect to major cardiovascular events (cardiovascular death, myocardial infarction, stroke…
- Conditions
- Atherosclerotic Cardiovascular Disease, Older Patients, LDL Cholesterol
- Trial name
- NCT05765370
- Testing
- Achieving a Target LDL-C level of 25mg/dL≤ LDL-C<70mg/dL, Achieving a Target LDL-C level of 70mg/dL≤ LDL-C<100mg/dL
- Where
- China
- Volunteers
- 4,200 people
- Sponsor
- China National Center for Cardiovascular Diseases
Acceptance of Visible Chronic Dermatological Disease, Disease Acceptance
Measure of Acceptance of chRonic Visible sKin conditionS
The objective of this protocol is to validate 4 scales for evaluating the acceptance of visible chronic dermatological diseases (port wine stains, alopecia areata, vitiligo, hyperpigmentation...) with a large number of patients…
- Conditions
- Acceptance of Visible Chronic Dermatological Disease, Disease Acceptance, Psychological Well-Being, Social Segregation
- Trial name
- MARKS (NCT06103903)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 250 people
- Sponsor
- University Hospital, Tours
Tooth Bleaching
Efficacy of Two Sonic Toothbrushes in Reducing Extrinsic Tooth Stain
The objective of the present study was to compare the effects of reduction of extrinsic stains between 2 commercially available Oclean sonic toothbrushes in comparison with an Oral-B manual toothbrush.
- Trial name
- NCT05202093
- Testing
- the Oclean Digital Visual toothbrush (2.16 N·cm torque), Oral B manual toothbrush, the Oclean Sonic Electric toothbrush (1.96 N·cm torque)
- Where
- China
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Corneal Staining
Comfort Evaluation of a New MPS vs. Replenish in Contact Lens Patients
To compare corneal staining after contact lens instillation with a new MPS vs. RepleniSH
- Trial name
- NCT00518700
- Testing
- new MPS, RepleniSH
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Innovative Medical
Neurologic Findings
Methylene Blue Intra-vital Nerve Staining
In previous studies, we know methylene blue (MB) stains nerves, and oxidized MB has near-infrared (NIR) fluorescence for fluorescent observation.
- Trial name
- NCT05547685
- Testing
- Methylene blue intradermal injection
- Where
- Taiwan
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital