Clinical trials: Staining
Foreign Bodies, Ultrasound
Foreign Body Removal With the Assistance of Ultrasound Guidance and Methylene Blue Staining in Children
Soft-tissue foreign bodies (FB) are very commonly observed in pediatric emergency departments. Some are metallic and can be diagnosed easily via X-ray radiography, whereas others are radiolucent and are hence less easily…
- Trial name
- NCT05085509
- Testing
- US guidance and MB staining
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Yuxi Su
Serous Papillary Endometrial Cancer
P16 Staining as Prognostic Biomarker in Serous Papillary Endometrial Cancer
P16 is a tumor suppressor protein implicated in serous papillary endometrial carcinoma. Evidence from previous trials indicates that it may be used as a diagnostic biomarker distinguishing this disease from endometrioid…
- Trial name
- NCT01267357
- Testing
- no intervention
- Where
- Israel
- Volunteers
- 62 people
- Sponsor
- Rambam Health Care Campus
Healthy
Testing Performance and Usability of Q300 Device
A data collection clinical study performed on live human spermatozoa samples. Spermatozoa are imaged by QART Q300TM microscopy system. For the feasibility 1st phase of the study, up to 75 donors are expected to participate.
- Trial name
- NCT04901572
- Testing
- QISI device
- Where
- 4 sites in Israel
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- QART Medical
Port-Wine Stain, Rosacea
Skin Imaging to Inform Laser Treatments
The purpose of this study is to obtain information (such as lesion depth, depth of the most superficial part of the lesion, and the size and density of blood vessels) with the assistance of an imaging device, and use this…
- Conditions
- Port-Wine Stain, Rosacea, Telangiectasia, Angioma
- Trial name
- NCT04336163
- Testing
- Optical Coherence Tomography
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Port Wine Stain
Pilot Study on the Use of the Matrix Radiofrequencyfor Treatment of Port Wine Stain Birthmarks
Port wine stain, also called nevus flammeus, is a congenital, cutaneous vascular malformation involving post-capillary venules which produces a light pink to red to dark-red-violet discoloration of the skin.
- Trial name
- NCT01166919
- Testing
- Matrix Radiofrequency
- Sponsor
- University of California, Irvine
Mouthwashes, Chlorhexidine
Effects of Two Daily CHX Mouthrinses on Plaque, Gingivitis and Staining
Τhe aim of this randomized clinical trial was to investigate the efficacy of two daily mouth rinses containing CHX and different combinations of H2O2 and CPC, when used adjunctive to mechanical oral hygiene, and compare them with…
- Conditions
- Mouthwashes, Chlorhexidine, Dental Plaque, Gingival and Periodontal Disease
- Trial name
- NCT07351370
- Testing
- chlorhexidine/ cetylpyridinium chloride/ hydrogen peroxide mouthwash, Chlorhexidine/ cetylpyridinium chloride
- Where
- Greece
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Dental School
Port-wine Stains
Treatment of Resistant Port-wine Stains With Bosentan and Pulsed Dye Laser: a Pilot Study
Pulsed dye laser (PDL) is the gold standard treatment for port-wine stains (PWS). However, the outcomes are highly variable due to the new angiogenesis occurring after laser irradiation.
- Trial name
- NCT02317679
- Testing
- Bosentan, Pulsed dye laser (PDL)
- Where
- France
- Volunteers
- 4 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Caries Infiltration, Fluorosis
Resin Infiltration and Resin Infiltration With Bleaching in Improving the Esthetics for Fluorosis Stains
Dental fluorosis is a clinical manifestation of chronic exposure to high intakes of fluoride during the tooth development. The present study is planned to evaluate the efficacy of Resin Infiltration technique in improving the…
- Conditions
- Caries Infiltration, Fluorosis, Dental Care
- Trial name
- NCT01733888
- Testing
- Office Bleaching, Resin Infiltration, Resin Infiltration twice
- Where
- 2 sites in India
- Volunteers
- 80 people
- Sponsor
- DMG Dental Material Gesellschaft mbH
Dry Eye
Clinical Efficacy of Two Topical Dry Eye Drops for Central Corneal Stain Clearing Over 90 Days
This study will be a randomized, double-blind prospective in 3 clinical sites to compare the efficacy of two currently approved topical ophthalmic drops in the clearing central corneal staining in 90 days prior to elective…
- Trial name
- NCT04172961
- Testing
- nanomicellular cyclosporine 0.09%, Lifitegrast
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Toyos Clinic
Port-Wine Stain
KTP Laser vs Pulsed Dye Laser for Port-Wine Stains
To compare the efficacy and safety of 532nm KTP laser and 585 nm pulsed dye laser for treating port-wine stains.
- Trial name
- NCT05771311
- Testing
- KTP, PDL
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Dry Eye Syndrome
Clinical Evaluation of Systane® ULTRA Compared to OPTIVE® in Ocular Surface Staining
The purpose of this study is to compare Systane® ULTRA lubricant eye drops to OPTIVE® lubricating eye drops for ocular surface staining within dry eye subjects and to evaluate the safety of Systane® ULTRA after 3 months of use.
- Trial name
- NCT01863368
- Testing
- Preservative-free saline solution eyedrops, Systane® ULTRA lubricant eyedrops, OPTIVE® lubricating eyedrops
- Volunteers
- 105 people
- Sponsor
- Alcon Research
Malignant Melanoma, Merkel Cell Carcinoma
Optical Biopsy of Human Skin in Conjunction With Laser Treatment
This study is to compare the ability of optical biopsy. Research can use light enters the skin, collected, analyzed by the computer, and a picture created for the pathologist to conventional histologic examination compare with…
- Conditions
- Malignant Melanoma, Merkel Cell Carcinoma, Basal Cell Carcinoma, Squamous Cell Carcinoma
- Trial name
- NCT00540566
- Testing
- Optical Biopsy imaging
- Where
- United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Tooth Stain
Combination of Dental Bleaching Techniques, Randomized Clinical Trial
To determine the effectiveness of combining different concentrations of hydrogen peroxide and carbamide used during tooth bleaching.
- Trial name
- NCT02682329
- Testing
- Hydrogen Peroxide and Carbamide Peroxide, Hydrogen Peroxide and Hydrogen Peroxide
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universidad Iberoamericana
Ureteral Injury
Investigating Oral Agents for Urine Staining to Facilitate Intraoperative Observation of Ureteral Jets
Recently, Indigo Carmine and Methylene Blue have been the standard agents to visualize ureteral jets during intraoperative cystoscopy.
- Trial name
- NCT03432572
- Testing
- Pyridium, Riboflavin, Thiamine
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Bacterial Infections
Development and Evaluation of AI Program for Predicting Bacterial Species From Urine Gram Stain Specimens
The purpose of this research is to develop an AI that estimates bacterial species from Gram staining images of urine specimens, and to evaluate the accuracy and labor reduction effect of Gram staining Automation system equipped…
- Trial name
- NCT06554145
- Where
- Japan
- Volunteers
- 15,000 people
- Sponsor
- GramEye
Tumor, Brain, Tumor, Breast
Microscopy Imaging of Whole-mount Stained Human Tissues
The goal of this clinical trial is to develop an imaging platform for intraoperative tumor margin delineation in 250 cases of tumor-suffered patients.
- Conditions
- Tumor, Brain, Tumor, Breast, Tumor Skin
- Trial name
- NCT05689112
- Where
- Taiwan
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Tooth Staining, Periodontitis
Impact of a Newly Formulated Toothpaste in Tooth Staining Associated With Chlorhexidine Rinses
Dental staining may interfere with compliance with chlorhexidine mouth rinse use Thus, developing strategies to control tooth staining associated with chlorhexidine use may be relevant for improving compliance.
- Trial name
- PaSTaining (NCT05354986)
- Testing
- Toothpaste with hexametaphosphate, tripolyphosphate and polyvinylpyrrolidone (PVP), Toothpaste without hexametaphosphate, tripolyphosphate and polyvinylpyrrolidone (PVP)
- Where
- Spain
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Tooth Discoloration
Safety and Efficacy of the ToothWave Powered Toothbrush for Extrinsic Stain Reduction (Texas)
This study is a single blind, prospective study aimed to evaluate the safety and efficacy of the Silk'n ToothWave Powered Toothbrush for stains reduction and improvement of teeth shade.
- Trial name
- NCT04092062
- Testing
- ToothWave, powered toothbrush
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Home Skinovations Ltd.
Healthy Adult Participants, Tooth Stain
Oil Pulling Whitening Mouthwash
The goal of this study is to evaluate the tooth whitening efficacy of Oil Pulling oral rinse compared to a competitor's whitening mouthwash and a water-based mouthwash (placebo).
- Trial name
- NCT07667088
- Testing
- GuruNanda natural Oil Pulling oral rinse, Therabreath Whitening Mouthwash - Dazzling Mint, GuruNanda water-based non-whitening mouthwash
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Macular Pucker, Macular Hole
Membrane Blue Versus Infracyanine Green
To compare possible toxicities of membrane blue and infracyanine green in vivo by macular function and peripheral visual field.
- Trial name
- NCT00555269
- Volunteers
- 30 people
- Sponsor
- The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery